公开(公告)号：US11801231B2

公开(公告)日：2023-10-31

申请号：US16226122

申请日：2018-12-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. Wlaschin ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. Oxman ,  Jie Yang

IPC: A61K31/164 ,  A61K9/00 ,  A61K9/107 ,  A61K47/02 ,  A61K47/10 ,  A61P1/02 ,  A61K47/26 ,  A61K47/44

CPC classification number: A61K31/164 ,  A61K9/0053 ,  A61K9/107 ,  A61K47/02 ,  A61K47/10 ,  A61K47/26 ,  A61K47/44 ,  A61P1/02

Abstract: Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition

HOCH2—(CHOH)n—CH2NR1R2  (I)

wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.

公开(公告)号：US11696879B2

公开(公告)日：2023-07-11

申请号：US16302394

申请日：2017-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jie Yang ,  Richard P. Rusin ,  Petra L. Kohler Riedi ,  Joel D. Oxman ,  Jodi L. Connell

IPC: A61K8/25 ,  A61K8/24 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00

CPC classification number: A61K8/25 ,  A61K8/24 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00 ,  A61K2800/87 ,  A61K2800/88

Abstract: Dental pastes are provided which include: (i) a compound of Formula (I), (ii) a compound of Formula (II) or a pharmaceutically acceptable salt thereof, and (iii) a dental abrasive.

公开(公告)号：US11666523B2

公开(公告)日：2023-06-06

申请号：US16644415

申请日：2018-08-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Carola A. Carrera Vidal ,  Joel D. Oxman ,  Jennifer J. Post ,  Paul R. Klaiber

IPC: A61K8/81 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00

CPC classification number: A61K8/8147 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00 ,  A61K2800/5426 ,  A61K2800/56

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patients tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

公开(公告)号：US20220211603A1

公开(公告)日：2022-07-07

申请号：US17594914

申请日：2020-05-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Jie Yang ,  Petra L. Kohler Riedi ,  Jodi L. Connell ,  Ingo Haeberlein ,  Hannah C. Cohen ,  Katie F. Wlaschin ,  Paul R. Klaiber ,  Yizhong Wang ,  Joel D. Oxman ,  Tiffany T. Ton ,  Roxanne A. Boehmer

IPC: A61K8/60 ,  A61K8/04 ,  A61Q11/00

Abstract: A composition comprising from 1 wt-% to 3 wt-% total of glucosamine a derivative of glucosamine, or a combination thereof based on the total weight of the composition, and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula (I): HOCH2—(OHOH)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3 and SO2R4 with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group and an aralkyl group, wherein n is an integer from 2 to 5.

公开(公告)号：US20220192953A1

公开(公告)日：2022-06-23

申请号：US17594878

申请日：2020-05-20

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Jie Yang ,  Petra L. Kohler Riedi ,  Jodi L. Connell ,  Ingo Haeberlein ,  Katie F. Wlaschin ,  Hannah C. Cohen ,  Tiffany T. Ton ,  Paul R. Klaiber ,  Yizhong Wang ,  Joel D. Oxman

IPC: A61K8/44 ,  A61K8/60 ,  A61Q11/00

Abstract: A composition comprising: from 0.2 wt-% to 3 wt-% total of arginine, glycine, or a combination thereof based on the total weight of the composition; and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula I: HOCH2—(CHOH)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5.

公开(公告)号：US11319440B2

公开(公告)日：2022-05-03

申请号：US16946253

申请日：2020-06-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Sheng Ye ,  Junting Li ,  Yizhong Wang ,  Joel D. Oxman ,  Susan E. DeMoss ,  Jonathan D. Zook

IPC: C08L81/02 ,  B64D45/02 ,  C08G18/04 ,  C08G75/02 ,  C09J181/02 ,  C08L81/00 ,  C08G75/00 ,  B05D3/02 ,  C08F8/34

Abstract: Compositions that are curable to polythioether polymers are provided, comprising: a) a dithiol monomer; b) a diene monomer; c) a radical cleaved photoinitiator; d) a peroxide; and e) an amine; where the peroxide and amine together are a peroxide-amine redox initiator. In some embodiments, the amine is a tertiary amine. In some embodiments, the amine is selected from the group consisting of dihydroxyethyl-p-toluidine, N,N-diisopropylethylamine, and N, N, N′, N″, N″-pentamethyl-diethylenetriamine. In some embodiments, the peroxide is selected from the group consisting of di-tert-butyl peroxide, methyl ethyl ketone peroxide, and benzoyl peroxide. In some embodiments, the composition may additionally comprise a polythiol monomer having three or more thiol groups.

公开(公告)号：US20220080019A1

公开(公告)日：2022-03-17

申请号：US17419516

申请日：2019-12-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Hannah C. Cohen ,  Katie F. Wlaschin ,  Yizhong Wang ,  Amanda C. Engler ,  Jie Yang ,  Tiffany T. Ton ,  Joel D. Oxman

IPC: A61K36/886 ,  A61K9/00 ,  A61K47/44 ,  A61K47/42 ,  A61K47/36 ,  A61K31/519 ,  A61K31/728 ,  A61K31/198 ,  A61K31/205 ,  A61K31/355 ,  A61K31/714 ,  A61K31/4425 ,  A61K31/155 ,  A61K45/06 ,  A61K47/02

Abstract: Articles that include not greater than 60 wt-% of one or more plant based oil that is solid at 25° C. (room temperature), the weight percent based on the total weight of the article; and from 4 wt-% to 10 wt-% of gelatin, from 0.8 to 5 wt-% of agar, or a combination thereof, the weight percent based on the total weight of the article, wherein the article is solid set and homogeneous. Methods of using the articles and compositions for forming the articles are also disclosed.

公开(公告)号：US20220079976A1

公开(公告)日：2022-03-17

申请号：US17419527

申请日：2019-12-27

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Hannah C. Cohen ,  Katie F. Wlaschin ,  Yizhong Wang ,  Amanda C. Engler ,  Jie Yang ,  Tiffany T. Ton ,  Joel D. Oxman

IPC: A61K33/00 ,  A61K8/25 ,  A61K8/92

Abstract: Articles that include from 70 wt-% to 99 wt-% of one or more plant based oil that is solid at 25° C., the weight percent based on the total weight of the article; and from 0.5 wt-% to 10 wt-% of fumed silica, the weight percent based on the total weight of the article. Methods of use of the articles are also included.

公开(公告)号：US20220062157A1

公开(公告)日：2022-03-03

申请号：US17419397

申请日：2019-12-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Amanda C. ENGLER ,  Katie F. WLASCHIN ,  Hannah C. COHEN ,  Yizhong Wang ,  Tiffany T. TON ,  Jie Yang ,  Joel D. Oxman ,  Emily M. Wollmuth

IPC: A61K8/92 ,  A61K8/02 ,  A61Q11/00

Abstract: Articles that include from 20 wt-% to 45 wt-% of one or more plant based oils based on the total weight of the article; from 50 wt-% to 70 wt-% of one or more polymer film formers based on the total weight of the article; and from 5 wt-% to 15 wt-% of one or more humectants based on the total weight of the article. Further articles comprises this combination of oil, film former and humectant as a first layer adjacent to which a second layer comprises a mucoadhesive polymer. The articles may be used to prevent formation or maintenance of biofilm in an oral tissue, affect hydration loss in an oral tissue, affect lubricity or lubriciousness in an oral tissue or treat xerostomia or dry mouth. Preferred polymer film formers include pullulan, xanthan gum, HP guar, ethyl cellulose and carrageenan.

公开(公告)号：US11111320B2

公开(公告)日：2021-09-07

申请号：US16591055

申请日：2019-10-02

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： William H. Moser ,  Ann R. Fornof ,  Guy D. Joly ,  Serkan Yurt ,  Larry R. Krepski ,  Ahmed S. Abuelyaman ,  Afshin Falsafi ,  Bradley D. Craig ,  Joel D. Oxman ,  Babu N. Gaddam

IPC: C08F22/10 ,  C07F7/18 ,  C09J4/06 ,  C08F292/00 ,  A61K6/62 ,  A61K6/71 ,  A61K6/887 ,  C09D7/61 ,  C07C69/602 ,  C07F9/09 ,  C09D4/00 ,  C08K3/36

Abstract: Novel stress-reducing crosslinking oligomers that have application in dental restoratives, thin films, hardcoats, composites, adhesives, and other uses subject to stress reduction are described. The addition-fragmentation process of crosslinking results in a chain-transfer event that provides novel polymers that may be further functionalized. In addition, the addition-fragmentation oligomer comprises pendent functional groups that bond to a substrate by forming an ionic or covalent bond, or etch the substrate by chemically removing some material from the substrate.