Photonic crystal Raman sensors and methods including the same
    41.
    发明授权
    Photonic crystal Raman sensors and methods including the same 有权
    光子晶体拉曼传感器和方法包括相同

    公开(公告)号:US07466407B2

    公开(公告)日:2008-12-16

    申请号:US11413877

    申请日:2006-04-27

    IPC分类号: G01J3/44

    CPC分类号: G01J3/44 G01N21/658

    摘要: Raman-enhancing structures include a photonic crystal having a resonant cavity and at least one waveguide coupled to the resonant cavity. A nanostructure comprising a Raman-enhancing material is disposed proximate the resonant cavity of the photonic crystal. Raman-enhancing structures include a microdisk resonator, at least one waveguide coupled to the microdisk resonator, and a nanostructure comprising a Raman-enhancing material disposed proximate the microdisk resonator. Methods for performing Raman spectroscopy include generating radiation, guiding the radiation through a waveguide to a resonant cavity in a photonic crystal or a microdisk resonator, resonating the radiation in the resonant cavity or microdisk resonator, providing an analyte proximate the resonant cavity or microdisk resonator, subjecting the analyte to the resonating radiation, and detecting Raman scattered radiation.

    摘要翻译: 拉曼增强结构包括具有谐振腔和耦合到谐振腔的至少一个波导的光子晶体。 包含拉曼增强材料的纳米结构设置在光子晶体的谐振腔附近。 拉曼增强结构包括微盘谐振器,耦合到微盘谐振器的至少一个波导和包括靠近微盘谐振器设置的拉曼增强材料的纳米结构。 用于执行拉曼光谱的方法包括产生辐射,将辐射通过波导引导到光子晶体或微盘谐振器中的谐振腔,谐振谐振腔或微盘谐振器中的辐射,提供靠近谐振腔或微盘谐振器的分析物, 对分析物进行共振辐射,并检测拉曼散射辐射。

    Systems and methods for detection of Raman scattered photons
    42.
    发明授权
    Systems and methods for detection of Raman scattered photons 有权
    用于检测拉曼散射光子的系统和方法

    公开(公告)号:US07405822B2

    公开(公告)日:2008-07-29

    申请号:US11584020

    申请日:2006-10-20

    IPC分类号: G01J3/44 G01N21/65

    CPC分类号: G01J3/44 G01N21/658

    摘要: Raman spectroscopy systems include an analyte, a radiation source configured to emit incident radiation having a wavelength, and a detector that is capable of detecting only radiation having wavelengths within a detectable range that includes at least one wavelength corresponding to hyper Raman scattered radiation scattered by the analyte. The wavelength of the incident radiation is outside the detectable range. In particular systems, all wavelengths of radiation that are scattered in the direction of the detector impinge on the detector. Raman spectroscopy methods include providing an analyte and irradiating the analyte with incident radiation having a wavelength, providing a detector capable of detecting only wavelengths of radiation within a detectable range that does not include the wavelength of the incident radiation, and detecting Raman scattered radiation scattered by the analyte. A continuous path free of radiation filters may be provided between the analyte and the detector.

    摘要翻译: 拉曼光谱系统包括分析物,被配置为发射具有波长的入射辐射的辐射源,以及检测器,其能够仅检测波长在可检测范围内的辐射,所述波长包括对应于由所述波长散射的超拉曼散射辐射的至少一个波长 分析物。 入射辐射的波长在可检测范围之外。 在特定系统中,在检测器的方向上散射的所有辐射波长都照射在检测器上。 拉曼光谱方法包括提供分析物并用具有波长的入射辐射照射分析物,提供检测器,该检测器仅能够检测不包括入射辐射波长的可检测范围内的辐射波长,并且检测散射的拉曼散射辐射 分析物。 可以在分析物和检测器之间提供不含辐射过滤器的连续路径。

    Integrated modular system and method for enhanced Raman spectroscopy
    44.
    发明授权
    Integrated modular system and method for enhanced Raman spectroscopy 有权
    用于增强拉曼光谱的集成模块化系统和方法

    公开(公告)号:US07385691B2

    公开(公告)日:2008-06-10

    申请号:US11044676

    申请日:2005-01-27

    IPC分类号: G01J3/44 G01N21/65

    摘要: Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device for performing Raman spectroscopy comprises a substrate and a laser source disposed on the substrate. The laser source may be configured for emanating a laser radiation, which may irradiate an analyte disposed on a Raman enhancement structure. The Raman enhancement structure may be disposed on the substrate or apart from the substrate. The molecular analysis device also include a radiation receiver disposed on the substrate and configured for receiving a Raman scattered radiation, which may be generated by the irradiation of the analyte and Raman enhancement structure.

    摘要翻译: 公开了用于增强拉曼光谱和超拉曼的装置,系统和方法。 用于执行拉曼光谱的分子分析装置包括设置在基板上的基板和激光源。 激光源可以被配置为发射激光辐射,其可照射设置在拉曼增强结构上的分析物。 拉曼增强结构可以设置在基板上或者离开基板。 分子分析装置还包括设置在基板上并被配置为用于接收可以通过分析物的照射和拉曼增强结构产生的拉曼散射辐射的辐射接收器。

    Wavelength-tunable excitation radiation amplifying structure and method
    45.
    发明授权
    Wavelength-tunable excitation radiation amplifying structure and method 有权
    波长可调激发辐射放大结构及方法

    公开(公告)号:US07307719B2

    公开(公告)日:2007-12-11

    申请号:US10941714

    申请日:2004-09-14

    IPC分类号: G01J3/44 G01J3/45

    CPC分类号: G01N21/658 G01J3/26

    摘要: Wavelength-tunable radiation amplifying structures for Raman spectroscopy are disclosed that include resonant cavities having Raman signal-enhancing structures disposed therein. Systems that include the amplifying structures and methods of performing spectroscopic analysis using the structures and systems are also disclosed.

    摘要翻译: 公开了用于拉曼光谱的波长可调辐射放大结构,其包括其中布置有拉曼信号增强结构的谐振腔。 还公开了包括放大结构的系统和使用该结构和系统进行光谱分析的方法。

    Nanochannel apparatus and method of fabricating
    46.
    发明申请
    Nanochannel apparatus and method of fabricating 审中-公开
    纳米通道装置及其制造方法

    公开(公告)号:US20070122313A1

    公开(公告)日:2007-05-31

    申请号:US11291019

    申请日:2005-11-30

    IPC分类号: B01L3/00

    摘要: A nanochannel apparatus and method of fabrication provide an array of nanochannels with distal open or exposed ends formed in situ through a permanent support. A nanofluidic system includes the nanochannel apparatus, a fluidic interface, and a component interfaced to the nanochannel apparatus. The method includes encasing an array of nanowires in a support, and forming the array of nanochannels in situ in locations of the nanowires, such that distal ends of the nanochannels are exposed.

    摘要翻译: 纳米通道装置和制造方法提供具有通过永久支撑原位形成的远端开放或暴露端的纳米通道阵列。 纳米流体系统包括纳米通道装置,流体界面和与纳米通道装置相连接的部件。 该方法包括将纳米线阵列包围在支撑体中,并且在纳米线的位置上原位形成纳米通道阵列,使得纳米通道的远端被暴露。

    Method and apparatus for molecular analysis using nanoelectronic circuits
    47.
    发明申请
    Method and apparatus for molecular analysis using nanoelectronic circuits 有权
    使用纳米电子电路进行分子分析的方法和装置

    公开(公告)号:US20060275778A1

    公开(公告)日:2006-12-07

    申请号:US11144586

    申请日:2005-06-03

    IPC分类号: C12Q1/68 C12M1/34

    摘要: Devices and methods for detecting the constituent parts of biological polymers are disclosed. A molecular analysis device comprises a molecule sensor and a molecule guide. The molecule sensor comprises a single electron transistor including a first terminal, a second terminal, and a nanogap or at least one quantum dot positioned between the first terminal and the second terminal. A nitrogenous material disposed on the at least one quantum dot is configured for an interaction with an identifiable configuration of a molecule. The molecule sensor develops an electronic effect responsive to the interaction. The molecule guide is configured for guiding at least a portion of the molecule substantially near the molecule sensor to enable the interaction.

    摘要翻译: 公开了用于检测生物聚合物的组成部分的装置和方法。 分子分析装置包括分子传感器和分子引导件。 分子传感器包括单电子晶体管,其包括位于第一端子和第二端子之间的第一端子,第二端子和纳米隙隙或至少一个量子点。 设置在至少一个量子点上的含氮材料被配置用于与分子的可识别构型的相互作用。 分子传感器产生响应于相互作用的电子效应。 分子引导件被配置用于基本上在分子传感器附近引导分子的至少一部分,以实现相互作用。

    Custom electrodes for molecular memory and logic devices
    49.
    发明申请
    Custom electrodes for molecular memory and logic devices 审中-公开
    用于分子存储器和逻辑器件的定制电极

    公开(公告)号:US20050164412A1

    公开(公告)日:2005-07-28

    申请号:US10995608

    申请日:2004-11-22

    摘要: A method for tailoring at least portions of an exposed non-planar layered surface of a conductive layer formed on a substrate having a first surface roughness to provide the exposed surface with a second surface roughness. The method includes: forming the conductive layer on the substrate; and tailoring at least portions of the exposed surface of the conductive layer in a plasma to at least smooth the exposed surface of the conductive layer, whereby the second surface roughness is essentially the same as the first surface roughness.

    摘要翻译: 一种用于调整形成在具有第一表面粗糙度的基底上的导电层的暴露的非平面层状表面的至少一部分以提供具有第二表面粗糙度的暴露表面的方法。 该方法包括:在基板上形成导电层; 以及在等离子体中定制导电层的暴露表面的至少部分,以至少平滑导电层的暴露表面,由此第二表面粗糙度基本上与第一表面粗糙度相同。