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    System and method for generating an adjusted fluid responsiveness metric
    41.
    发明授权
    System and method for generating an adjusted fluid responsiveness metric 有权

    公开(公告)号：US11317821B2

    公开(公告)日：2022-05-03

    申请号：US15702112

    申请日：2017-09-12

    Applicant: Covidien LP

    Inventor： Paul Stanley Addison ,  Rui Wang ,  Scott McGonigle ,  James N. Watson

    IPC: A61B5/02 ,  A61B5/0295 ,  A61B5/022 ,  A61B5/08 ,  A61B5/1455

    Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient includes an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue. The monitor also includes a perfusion status indicator indicating a perfusion status of the PPG signal, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP value based on a respiratory variation of the PPG signal. The FRP calculator applies a correction factor based on the perfusion status indicator.

    METHODS AND SYSTEMS FOR DETERMINING FLUID RESPONSIVENESS
    45.
    发明申请
    METHODS AND SYSTEMS FOR DETERMINING FLUID RESPONSIVENESS 审中-公开
    用于确定流体响应的方法和系统

    公开(公告)号：US20160073965A1

    公开(公告)日：2016-03-17

    申请号：US14846590

    申请日：2015-09-04

    Applicant: Covidien LP

    Inventor： Paul Stanley Addison ,  Scott McGonigle ,  James Nicholas Watson ,  Rui Wang ,  Peter Doyle

    IPC: A61B5/00 ,  A61B5/091 ,  A61B5/08

    CPC classification number: A61B5/091 ,  A61B5/02028 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/14551 ,  A61B5/4848

    Abstract: Methods and systems are provided for determining fluid responsiveness based on a physiological signal. The system may determine fluid responsiveness based on the physiological signal and receive or determine respiration information of the subject. The system may correct the fluid responsiveness based on the respiration information. In some embodiments, the system may determine a correction factor to correct the fluid responsiveness values based on a relationship between fluid responsiveness and the respiration information. In some embodiments, the system may correct the measured fluid responsiveness based on an error between the fluid responsiveness measure and another measure such as pulse pressure variation, where there is a relationship between the error and the respiration information.

    Abstract translation: 提供了用于基于生理信号确定流体响应性的方法和系统。 系统可以基于生理信号确定流体响应性，并且接收或确定对象的呼吸信息。 该系统可以基于呼吸信息来校正流体响应性。 在一些实施例中，系统可以基于流体响应性和呼吸信息之间的关系来确定校正因子以校正流体响应性值。 在一些实施例中，系统可以基于流体响应度测量和诸如脉冲压力变化的另一措施之间的误差校正所测量的流体响应性，其中误差和呼吸信息之间存在关系。

    APNEA ANALYSIS SYSTEM AND METHOD
    46.
    发明申请
    APNEA ANALYSIS SYSTEM AND METHOD 有权
    APNEA分析系统与方法

    公开(公告)号：US20150190088A1

    公开(公告)日：2015-07-09

    申请号：US14590609

    申请日：2015-01-06

    Applicant: Covidien LP

    Inventor： Bo Chen ,  Michael L. Mestek ,  Ron J. Kadlec ,  Niranjan Maharajh ,  Mark E. Kolnsberg ,  Corinne H. Johnson ,  James P. Ochs ,  Paul Stanley Addison ,  James N. Watson

    IPC: A61B5/00 ,  A61B5/1455 ,  A61B7/00 ,  A61B5/0205

    CPC classification number: A61B5/4818 ,  A61B5/02055 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/0836 ,  A61B5/087 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7235 ,  A61B5/7253 ,  A61B5/7264 ,  A61B5/7278 ,  A61B5/7282 ,  A61B7/003

    Abstract: An apnea analysis system may include a photoplethysmographic (PPG) sub-system, a breath detection sub-system, and an apnea analysis module. An apnea analysis system includes a photoplethysmographic (PPG) sub-system, a breath detection sub-system, and an apnea analysis module. The PPG sub-system is configured to be operatively connected to an individual and output a PPG signal from the individual. The breath detection sub-system is configured to be operatively connected to the individual and output a breath signal from the individual. The apnea analysis module is in communication with the PPG sub-system and the breath detection sub-system. The apnea analysis module analyzes the breath signal and a respiratory component of the PPG signal and, based on the analysis, identifies a presence of apnea, differentiates between obstructive apnea and central apnea, and provides an indication of the identified apnea.

    Abstract translation: 呼吸暂停分析系统可以包括光电体积描记术（PPG）子系统，呼吸检测子系统和呼吸暂停分析模块。 呼吸暂停分析系统包括光电体积描记术（PPG）子系统，呼吸检测子系统和呼吸暂停分析模块。 PPG子系统被配置为可操作地连接到个体并从个体输出PPG信号。 呼吸检测子系统被配置为可操作地连接到个体并从个体输出呼吸信号。 呼吸暂停分析模块与PPG子系统和呼吸检测子系统进行通信。 呼吸暂停分析模块分析呼吸信号和PPG信号的呼吸成分，并且基于分析，识别呼吸暂停的存在，区分阻塞性呼吸暂停和中枢性呼吸暂停，并且提供所识别的呼吸暂停的指示。

    SYSTEM AND METHOD FOR GENERATING AN ADJUSTED FLUID RESPONSIVENESS METRIC
    47.
    发明申请
    SYSTEM AND METHOD FOR GENERATING AN ADJUSTED FLUID RESPONSIVENESS METRIC 有权
    用于产生调节流体响应度的系统和方法

    公开(公告)号：US20140323822A1

    公开(公告)日：2014-10-30

    申请号：US14258141

    申请日：2014-04-22

    Applicant: COVIDIEN LP

    Inventor： Paul Stanley Addison ,  Rui Wang ,  Scott McGonigle ,  James N. Watson

    IPC: A61B5/00

    CPC classification number: A61B5/0295 ,  A61B5/022 ,  A61B5/0816 ,  A61B5/14551

    Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient includes an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue. The monitor also includes a perfusion status indicator indicating a perfusion status of the PPG signal, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP value based on a respiratory variation of the PPG signal. The FRP calculator applies a correction factor based on the perfusion status indicator.

    Abstract translation: 本发明涉及生理信号处理，特别涉及用于处理生理信号以预测患者的流体反应性的方法和系统。 用于监测患者的医疗监视器包括接收表示患者组织的光吸收的光谱体积描记图（PPG）信号的输入。 该监视器还包括指示PPG信号的灌注状态的灌注状态指示器和被编程为基于PPG信号的呼吸变化计算FRP值的流体响应性预测器（FRP）计算器。 FRP计算器根据灌注状态指示器应用校正因子。

    SYSTEM AND METHOD FOR DETERMINING REPETITIVE AIRFLOW REDUCTIONS
    49.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING REPETITIVE AIRFLOW REDUCTIONS 审中-公开
    用于确定重复减少气流的系统和方法

    公开(公告)号：US20140275938A1

    公开(公告)日：2014-09-18

    申请号：US13826164

    申请日：2013-03-14

    Applicant: COVIDIEN LP

    Inventor： Paul Stanley Addison ,  James Nicholas Watson

    IPC: A61B5/087 ,  A61B5/08

    CPC classification number: A61B5/0873 ,  A61B5/0826 ,  A61B5/14551 ,  A61B5/7214

    Abstract: Certain embodiments of the present disclosure provide a system and method for determining a repetitive airflow reduction of an individual. The system may include a photoplethysmogram (PPG) detection module configured to detect a PPG signal of a patient. The PPG signal may include a pulsatile AC component superimposed on a DC baseline. The system may also include a PPG baseline analysis module configured to analyze the DC baseline of the PPG signal to detect one or more threshold crossings with respect to an acceptable threshold correlated to normal breathing. The system may also include a repetitive airflow reduction determination module configured to determine an occurrence of the repetitive airflow reduction through an analysis of the one or more threshold crossings.

    Abstract translation: 本公开的某些实施例提供了一种用于确定个体的重复气流减少的系统和方法。 该系统可以包括被配置为检测患者的PPG信号的光电体积描记图（PPG）检测模块。 PPG信号可以包括叠加在DC基线上的脉动AC分量。 该系统还可以包括PPG基线分析模块，其被配置为分析PPG信号的DC基线，以检测相对于与正常呼吸相关的可接受阈值的一个或多个阈值交叉。 该系统还可以包括重复性气流减少确定模块，其被配置为通过分析一个或多个阈值交叉来确定重复气流减少的发生。

    Methods and Systems for Determining a Probe-Off Condition in a Medical Device
    50.
    发明申请
    Methods and Systems for Determining a Probe-Off Condition in a Medical Device 审中-公开
    用于确定医疗器械中的探针状态的方法和系统

    公开(公告)号：US20140275882A1

    公开(公告)日：2014-09-18

    申请号：US13797832

    申请日：2013-03-12

    Applicant: COVIDIEN LP

    Inventor： Paul Stanley Addison ,  James Nicholas Watson ,  Paul Mannheimer

    IPC: A61B5/1495 ,  A61B5/0205 ,  A61B5/1455

    CPC classification number: A61B5/1495 ,  A61B5/0205 ,  A61B5/02108 ,  A61B5/02416 ,  A61B5/14551

    Abstract: A physiological monitoring system may use one or more characteristics of an ambient signal to determine a probe-off condition. A physiological sensor may be used to emit one or more wavelengths of light. A light signal may be received that includes an ambient light component and one or more components corresponding to the emitted light. One or more characteristics (e.g., baseline characteristics) of the ambient light component may be determined and compared to one or more thresholds. The system may determine whether the physiological sensor is properly positioned based on the comparison.

    Abstract translation: 生理监测系统可以使用环境信号的一个或多个特性来确定探测条件。 可以使用生理传感器来发射一个或多个波长的光。 可以接收包括环境光分量和对应于发射光的一个或多个分量的光信号。 可以确定环境光分量的一个或多个特征（例如，基线特性）并将其与一个或多个阈值进行比较。 该系统可以基于比较来确定生理传感器是否正确定位。

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