Abstract:
Novel 5-amino-5,6,7,8-tetrahydroquinolines and related compounds, intermediates and processes for the preparation thereof, and methods for relieving memory dysfunction utilizing compounds or compositions thereof are disclosed.
Abstract:
A method and apparatus for frequency shifting an optical beam where the frequency shifted beam remains both spatially and temporally coherent with no spread in frequency and can be continually tuned in frequency shift over a wide range without any change in beam pointing or beam quality with time. This is achieved by changing the effective optical path length of the resonant cavity of a laser by translating an optical wedge, such as a prism, across the optical path in the direction of the wedge gradient. In a first embodiment, a rotating helical phase plate is used to linearly increase the optical path of a transmitted or reflected beam with time, thereby frequency shifting the exiting beam. In another embodiment, the rim of a wheel with a spirally increasing or decreasing radius is used in which the outer periphery of the wheel is a mirror. Spinning the wheel at a constant rotational speed increases or decreases the optical path of a reflected beam linearly with time, thereby frequency shifting the reflected beam. The helical phase plate can be used in either a transmissive mode or a reflective mode, whereas the spiral wheel is used primarily in a reflective mode.
Abstract:
A waveguide coupler comprises a curved end reflector mirror that images a waveguide exit back into the waveguide with an essentially exact reproduction of the waveguide output intensity distribution. The coupler also comprises a lens disposed near the waveguide exit at a point between the exit and the mirror, the lens providing a phase compensation to the beam passing therethrough such that the phase of the beam returned to the waveguide matches that of the exiting beam. Thus, coupling losses due to clipping of the returned beam at the exit/entrance to the waveguide bore and coupling losses due to a mismatch of the returning field phase to that of the waveguide mode are made essentially zero. Other embodiments of the coupler are presented wherein the phase compensating lens is positioned at locations other than adjacent to the waveguide exit, or wherein no inversion of the imaged field field distribution occurs, or wherein the beam is not caused to be focused at the center of a lens, or wherein one waveguide is coupled to another waveguide having a similar sized or a dissimilar sized bore.
Abstract:
This invention forces a multi-spectral line laser to operate on a single spectral line by modifying the gain of the medium instead of the standard approach of modifying the loss of the cavity. The spectral line selected by the system of the present invention is always the same identical spectral line. There are no ambiguities in knowing which line has been selected as there are with other methods. The invention involves a system for using more than one type of gain media within the laser cavity. Each medium gives rise to a distinct set of spectral line frequencies at which it has gain. Only occassional coincidences will occur at which spectral lines from two or more media fall within a linewidth of each other. Where these coincidences do not occur, the gain for a spectral line is only proportional to the amount of the individual medium present and will be below threshold. Where the coincidences do occur, the total gain is proportional to the total amount of gain for all of the involved media and the line will lase. Spectral lines that are within one operating linewidth of one another may be achieved by the use of two different types of gain media within the laser cavity. The most promising embodiment of the present invention is to use the same type of gain media but with different isotopes, which would, in many but not all cases, allow a physical mixing of the media within the resonant cavity. Each medium or isotope gives rise to a different and distinct set of spectral line frequencies at which the system has gain. Only occasional coincidences will occur at which spectral lines from two or more media fall within a linewidth of each other. Where these coincidences do not occur, the gain for a spectral line is only proportional to the amount of the individual medium present and will be below threshold. Where the coincidences do occur, the total gain is proportional to the total amount of all the involved media and the line will lase.
Abstract:
A method for providing access to operation information relating to a digital signal, including providing a digital signal encoded, in accordance with a layered encoding scheme, in a plurality of layers, and extracting operation information from a first layer of encoding within the digital signal, and placing the extracted information in a data section in a second layer of encoding within the digital signal. Related methods and apparatus are also described.
Abstract:
A wound dressing apparatus includes a wound dressing member dimensioned for positioning relative to a wound bed. The wound dressing member including an internal vacuum reservoir and has a port in communication with the vacuum reservoir for applying subatmospheric pressure to the vacuum reservoir to facilitate removal of fluid from the wound bed. The wound dressing member includes a visual pressure indicator associated therewith for indicating a level of pressure within the vacuum reservoir. The visual pressure indicator includes color indicia having a plurality of colors corresponding to a condition of the pressure within the vacuum reservoir. The wound dressing member includes a lower absorbent member positionable adjacent the wound bed and an upper member which at least partially defines the vacuum reservoir. At least one of the top member and the lower absorbent member has the visual pressure indicator mounted thereto.
Abstract:
A method for switching from playing a first compressed data segment to playing a second compressed recorded data segment, the method including playing an uncompressed copy of a start of the second compressed recorded data segment upon switching from playing the first compressed data segment, decoding the second compressed recorded data segment from a preceding random access point, the preceding random access point preceding, in the second compressed recorded data segment, a point at which playing is to be switched to the second compressed recorded data segment, stopping the decoding of the second compressed recorded data segment when reaching a point beyond a point currently being played in the uncompressed copy, and switching to playing the second compressed recorded data segment when playing the uncompressed copy of a start of the second compressed recorded data segment reaches the point at which the decoding of the second compressed recorded data segment was stopped. Related apparatus and methods are also provided.
Abstract:
The invention relates to heterocyclic substituted carbonyl derivatives that display selective binding to dopamine D3 receptors. In another aspect, the invention relates to a method for treating central nervous system disorders associated with the dopamine D3 receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders. The subject invention is also directed towards processes for the preparation of the compounds described herein as well as methods for making and using the compounds as imaging agents for dopamine D3 receptors.