公开(公告)号：US08055351B2

公开(公告)日：2011-11-08

申请号：US12090583

申请日：2006-10-20

Applicant: Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Eldelstein ,  Parag V. Karmarkar

Inventor： Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Eldelstein ,  Parag V. Karmarkar

IPC: A61N1/00

CPC classification number: A61N1/06 ,  A61N1/056 ,  A61N1/086

Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli The devices can include at least one electrode.

Abstract translation: 一些实施例涉及MRI / RF兼容医疗介入装置。 多个间隔开的高阻抗电路段被配置为在高频范围内具有高阻抗，并且在低频率范围内具有低阻抗。高阻抗电路段可以包括共绕线圈电感器并且可以减少，阻塞或 在暴露于与高磁铁MRI系统相关联的RF的同时，沿着引导系统（20）抑制RJ-传输，同时置换低频生理信号，治疗和/或刺激的通过。该装置可以包括至少一个电极。

公开(公告)号：US20110257516A1

公开(公告)日：2011-10-20

申请号：US13087621

申请日：2011-04-15

Applicant: Haydar Celik ,  Ergin Atalar

Inventor： Haydar Celik ,  Ergin Atalar

IPC: A61B5/055

CPC classification number: A61B5/062 ,  A61B5/055

Abstract: In a method for detecting rotational orientation and position tracking of an inductively coupled RF (ICRF) coil using a transmit array system, a conventional body birdcage coil is used, but the quadrature hybrid is eliminated to use the two excitation-channels separately. The transmit array system provides RF excitations such that the body birdcage coil creates linearly polarized and circulating RF pulses instead of a conventional rotational forward polarized excitation. Inductively coupled RF (ICRF) coils can be constructed on catheters for detecting rotational orientation and tracking purposes. The modifications on anatomy and ICRF coil images are different due to the RF excitation scheme such that the ICRF coil can be separated from the anatomy in real-time. After separating the ICRF coil from the anatomy, a color-coded image can be reconstructed, for example.

Abstract translation: 在使用发射阵列系统检测电感耦合RF（ICRF）线圈的旋转取向和位置跟踪的方法中，使用常规的身体鸟笼线圈，但是消除正交混合以分别使用两个激励信道。 发射阵列系统提供RF激励，使得主体鸟笼线圈产生线性偏振和循环RF脉冲，而不是传统的旋转正向偏振激励。 电感耦合RF（ICRF）线圈可以构建在用于检测旋转取向和跟踪目的的导管上。 解剖和ICRF线圈图像的修改由于RF激励方案而不同，使得ICRF线圈可以与解剖结构实时分离。 在将ICRF线圈与解剖结构分开之后，例如可以重建颜色编码的图像。

公开(公告)号：US20110257515A1

公开(公告)日：2011-10-20

申请号：US13086577

申请日：2011-04-14

Applicant: Ergin Atalar ,  Nikolay V. Visksenko

Inventor： Ergin Atalar ,  Nikolay V. Visksenko

IPC: A61B5/055

CPC classification number: A61B5/055 ,  G01R33/34084

Abstract: A radio-frequency (RF) coil for obtaining magnetic resonance data for imaging the cervical region of a patient has a loop coil contained in a housing of an applicator assembly that is adapted for placement against the cervix of the patient, and a loopless antenna contained in a tandem applicator of the assembly, that is adapted for intracorporeal placement in the cervix of the patient.

Abstract translation: 用于获得用于对患者的颈部区域成像的磁共振数据的射频（RF）线圈具有包含在施加器组件的壳体中的环形线圈，其适于放置抵靠患者的子宫颈，并且包含无孔天线 在组件的串联施放器中，其适于体内放置在患者的子宫颈中。

公开(公告)号：US07848788B2

公开(公告)日：2010-12-07

申请号：US10123065

申请日：2002-04-11

Applicant: Steve Tulley ,  Albert C. Lardo ,  Parag Karmarkar ,  Elliot McVeigh ,  Henry R. Halperin ,  Christine Enger McNamara ,  Paul A. Bottomley ,  Ergin Atalar ,  Xiaoming Yang

Inventor： Steve Tulley ,  Albert C. Lardo ,  Parag Karmarkar ,  Elliot McVeigh ,  Henry R. Halperin ,  Christine Enger McNamara ,  Paul A. Bottomley ,  Ergin Atalar ,  Xiaoming Yang

IPC: A61B5/055

CPC classification number: G01R33/34084 ,  A61M25/09 ,  G01R33/287 ,  G01R33/34053 ,  G01R33/3657 ,  H01Q1/36 ,  H01Q1/362 ,  H01Q1/40 ,  H01Q1/42 ,  H01Q1/44 ,  H01Q11/08

Abstract: Herein is disclosed a magnetic resonance imaging probe, having a probe shaft including a magnetic resonance antenna, and a spring tip attached to a distal end of the antenna.

Abstract translation: 本文公开了一种磁共振成像探头，其具有包括磁共振天线的探针轴以及连接到天线远端的弹簧尖端。

公开(公告)号：US20100056900A1

公开(公告)日：2010-03-04

申请号：US12225198

申请日：2007-03-14

Applicant: Louis L. Whitcomb ,  Axel Krieger ,  Robert Charles Susil ,  Gabor Fichtinger ,  Ergin Atalar ,  Iulian I. Iordachita

Inventor： Louis L. Whitcomb ,  Axel Krieger ,  Robert Charles Susil ,  Gabor Fichtinger ,  Ergin Atalar ,  Iulian I. Iordachita

IPC: A61B5/055 ,  A61B5/00

CPC classification number: A61B5/064 ,  A61B5/055 ,  A61B6/12 ,  A61B8/12 ,  A61B10/0241 ,  A61B34/20 ,  A61B34/25 ,  A61B34/30 ,  A61B90/11 ,  A61B90/50 ,  A61B2017/00911 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378

Abstract: A device, system, and method for entering a medical device such as a needle into the body inside a medical imager such as a MRI scanner, CT, X-ray fluoroscopy, and ultrasound imaging, from within a body cavity (such as the rectum, vagina, or laparoscopically accessed cavity). A three degree-of-freedom mechanical device translates and rotates inside the cavity and enters a needle into the body, and steers the needle to a target point selected by the user. The device is guided by real-time images from the medical imager. Networked computers process the medical images and enable the clinician to control the motion of the mechanical device that is operated within the imager, outside of the imager or remotely from outside the imager.

Abstract translation: 一种用于将诸如针之类的医疗装置从医疗成像器（例如MRI扫描仪，CT，X射线透视和超声成像）内的体内进入体腔（例如直肠）的装置，系统和方法 ，阴道或腹腔镜腔）。 三自由度机械装置在空腔内平移和旋转，并将针进入身体，并将针转向由使用者选择的目标点。 该装置由来自医用成像器的实时图像引导。 联网的计算机处理医学图像并使临床医生能够控制在成像器内部，在成像器外部或远离成像仪外部操作的机械装置的运动。

公开(公告)号：US07599729B2

公开(公告)日：2009-10-06

申请号：US11136329

申请日：2005-05-24

Applicant: Ergin Atalar ,  Harald Hartmut Quick ,  Parag Karmarkar

Inventor： Ergin Atalar ,  Harald Hartmut Quick ,  Parag Karmarkar

IPC: A61B5/055

CPC classification number: G01R33/34084 ,  A61B1/273 ,  A61B1/303 ,  A61B1/307 ,  A61B1/31 ,  A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4381 ,  G01R33/285 ,  G01R33/34007 ,  G01R33/341 ,  H01Q1/36 ,  H01Q1/362 ,  H01Q1/40 ,  H01Q1/44 ,  H01Q11/08

Abstract: Systems and methods for the evaluation of the urethra and periurethral tissues may involve an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.

Abstract translation: 用于评估尿道和尿道周围组织的系统和方法可以包括适于插入到男性，女性或儿科尿道中的MRI线圈。 MRI线圈可以与由调谐匹配电路，去耦电路和平衡 - 不平衡转换电路组成的接口电路电连通。 接口电路也可以与MRI机器电连通。 在某些实践中，本发明提供了用于诊断和治疗涉及尿道和尿道周围组织的病症的方法，包括女性骨盆底部疾病，前列腺疾病和儿科骨盆异常。

公开(公告)号：US20080208034A1

公开(公告)日：2008-08-28

申请号：US12069865

申请日：2008-02-13

Applicant: Xiaoming Yang ,  Ergin Atalar ,  Christopher Yeung

Inventor： Xiaoming Yang ,  Ergin Atalar ,  Christopher Yeung

IPC: A61B5/055 ,  A61B18/18 ,  A61M25/10

CPC classification number: A61B18/1492 ,  A61B2018/00404 ,  A61B2018/144 ,  A61B2090/374 ,  A61B2218/002

Abstract: Featured are devices, systems and methods for localized heating of a vessel as well as devices, systems and methods for MR/NMR imaging of a vessel while locally heating a portion of the vessel. More particularly featured are such devices, systems and methods for use when administering or delivering therapeutic agents including genes and/or drugs to the tissues of the vessel. Such a method includes positioning a thermal energy delivery device proximal a target site within the vessel of a body and activating the thermal energy delivery device so as to heat the target site thereby locally increasing a temperature of tissue at the target site. In further embodiments, the method includes introducing a therapeutic medium to the target site over a predetermined time period, and wherein said activating occurs at least one of before, during or after said step of introducing.

Abstract translation: 特征是用于容器的局部加热的装置，系统和方法以及用于容器的MR / NMR成像的装置，系统和方法，同时局部加热容器的一部分。 更特别的特征是这样的装置，系统和方法，用于在向血管的组织施用或递送包括基因和/或药物的治疗剂时使用。 这种方法包括将热能输送装置定位在身体的容器内的靶部位附近，并激活热能递送装置，以便加热靶部位，从而局部增加靶部位的组织温度。 在另外的实施方案中，该方法包括在预定时间段内将治疗介质引入目标部位，并且其中所述激活发生在引入步骤之前，期间或之后的至少之一。

公开(公告)号：US07155271B2

公开(公告)日：2006-12-26

申请号：US10424093

申请日：2003-04-28

Applicant: Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

Inventor： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

IPC: A61B5/055

CPC classification number: A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

Abstract: A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.

公开(公告)号：US07078903B2

公开(公告)日：2006-07-18

申请号：US10850450

申请日：2004-05-21

Applicant: Vaishali Paliwal ,  Abdel-Monem El-Sharkawy ,  Ergin Atalar

Inventor： Vaishali Paliwal ,  Abdel-Monem El-Sharkawy ,  Ergin Atalar

IPC: G01V3/00

CPC classification number: G01R33/4804

Abstract: Disclosed is a method and system for steady state free precession based magnetic resonance thermometry that measures changes in temperature on a pixel by pixel basis. The method comprises generating an RF pulse sequence used to find the proton resonance frequency shift, which is proportional to temperature change, processing the resultant MRI data to measure the proton frequency shift, and converting the measured proton frequency shift into change in temperature data. Further disclosed is a method for identifying and compensating for temperature drifts due to core heating of the gradient magnet.

Abstract translation: 公开了一种用于基于逐个像素测量温度变化的基于稳态自由进动的磁共振测温法的方法和系统。 该方法包括产生用于找到与温度变化成比例的质子谐振频移的RF脉冲序列，处理所得到的MRI数据以测量质子频率偏移，并将测量的质子频移转换为温度数据变化。 进一步公开的是用于识别和补偿由于梯度磁体的核心加热引起的温度漂移的方法。

公开(公告)号：US06408202B1

公开(公告)日：2002-06-18

申请号：US09432960

申请日：1999-11-03

Applicant: Joao A. C. Lima ,  Kendrick A. Shunk ,  Ergin Atalar

Inventor： Joao A. C. Lima ,  Kendrick A. Shunk ,  Ergin Atalar

IPC: A61B505

CPC classification number: G01R33/34084 ,  G01R33/34 ,  G01R33/34053 ,  G01R33/3657

Abstract: A method of transesophageal magnetic resonance analysis of a patient, such as an animal or human, includes providing a loopless antenna formed from a flexible coaxial cable having an extended center conductor at the distal end thereof. A distal portion of the loopless antenna is secured within a Levin-type gastric tube. The gastric tube which receives the loopless antenna is inserted in the esophagus of the patient. A tuning, matching and decoupling circuit for the loopless antenna is employed external to the patient. The tuning, matching and decoupling circuit is electrically connected to a magnetic resonance imaging scanner. The magnetic resonance imaging scanner is employed to display an image of the aorta of the patient.

Abstract translation: 患者（例如动物或人）的经食管磁共振分析的方法包括提供由其远端具有延伸的中心导体的柔性同轴电缆形成的无孔天线。 无孔天线的远端部分固定在Levin型胃管内。 接收无腰天线的胃管插入患者的食道。 用于无孔天线的调谐，匹配和去耦电路在患者外部使用。 调谐，匹配和去耦电路电连接到磁共振成像扫描仪。 使用磁共振成像扫描器来显示患者的主动脉的图像。