公开(公告)号：US06849656B1

公开(公告)日：2005-02-01

申请号：US10070484

申请日：2000-09-15

申请人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani

发明人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani

IPC分类号： C07D209/12 ,  C07F9/24 ,  C07F9/572 ,  A61K31/404

CPC分类号： C07F9/247 ,  C07D209/12 ,  C07F9/5728

摘要： Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as prodrugs, may well prove to be tumor selective vascular targeting and destruction chemotherapeutic agents or to have anti-angiogenesis activity resulting in the selective prevention and/or destruction of tumor cell vasculature.

摘要翻译： 已经发现了三甲氧基苯基取代的吲哚配体，其表现出令人印象深刻的细胞毒性以及抑制微管蛋白聚合的显着能力。 这些化合物以及相关衍生物是用于治疗人类癌症的优异临床候选物。 此外，作为前药的这些配体中的某些可以很好地证明是肿瘤选择性血管靶向和破坏化学治疗剂，或具有抗血管生成活性，导致选择性预防和/或破坏肿瘤细胞脉管系统。

公开(公告)号：US06613874B1

公开(公告)日：2003-09-02

申请号：US09537789

申请日：2000-03-29

申请人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

发明人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

IPC分类号： C07K750

CPC分类号： C07K14/685 ,  A61K38/00 ,  C07K14/68

摘要： Disclosed are cyclic peptide analogs that are MC-4 and/or MC-3 receptor ligands, the analogs having a structure according to Formula (I): wherein B, X, E, Z, D, G, M′, W, R, R1, R1′, R11, m, n, p and q are as described in the specification. The peptide analogs are useful in treating diseases that are mediated by the MC-4 and/or the MC-3 receptor. As such, the invention is directed to methods of treating body weight disorders, such as obesity, anorexia, and cachexia. The invention also relates to the treatment of CNS depression, behavior-related disorders, memory-related disorders, cardiovascular function, inflammation, sepsis, septic shock, cardiogenic shock, hypovolemic shock, sexual dysfunction, erectile dysfunction, muscle atrophy, diseases associated with nerve growth and repair, and intrauterine fetal growth. Also disclosed are pharmaceutical compositions comprising the peptide analogs of Formula (I).

摘要翻译： 公开了作为MC-4和/或MC-3受体配体的环肽类似物，该类似物具有式（I）的结构：其中B，X，E，Z，D，G，M'，W，R ，R1，R1'，R11，m，n，p和q如说明书中所述。 肽类似物可用于治疗由MC-4和/或MC-3受体介导的疾病。 因此，本发明涉及治疗体重障碍，例如肥胖症，厌食症和恶病质的方法。 本发明还涉及CNS抑郁症，行为相关障碍，记忆相关障碍，心血管功能，炎症，败血症，败血症休克，心源性休克，血容量不足休克，性功能障碍，勃起功能障碍，肌肉萎缩，与神经相关的疾病 生长和修复，宫内胎儿生长。 还公开了包含式（I）的肽类似物的药物组合物。

公开(公告)号：US06473265B1

公开(公告)日：2002-10-29

申请号：US09572664

申请日：2000-05-16

申请人： Yuming Zhou ,  Feng Wang ,  Jim Giusti ,  Juan Fernandez-de-Castro

发明人： Yuming Zhou ,  Feng Wang ,  Jim Giusti ,  Juan Fernandez-de-Castro

IPC分类号： G11B531

CPC分类号： G11B5/313 ,  G11B5/127 ,  G11B5/3116 ,  G11B5/40 ,  G11B33/14

摘要： A magnetic recording head has an air bearing surface and a magnetic core having a height and a width. The magnetic core is formed in part of a plurality of narrow slices having a plurality of insulating channels interspersed therein along the width of the magnetic core. Each of the plurality of narrow slices extends essentially along the height of the magnetic core.

摘要翻译： 磁记录头具有空气轴承表面和具有高度和宽度的磁芯。 磁芯形成在多个窄片的一部分中，该多个窄片具有沿着磁芯的宽度分布在其中的多个绝缘通道。 多个窄片中的每一个基本上沿着磁芯的高度延伸。

公开(公告)号：US09449851B2

公开(公告)日：2016-09-20

申请号：US14833407

申请日：2015-08-24

申请人： Dillon Wong ,  Jairo Velasco, Jr. ,  Long Ju ,  Salman Kahn ,  Juwon Lee ,  Chad E. Germany ,  Alexander K. Zettl ,  Feng Wang ,  Michael F. Crommie

发明人： Dillon Wong ,  Jairo Velasco, Jr. ,  Long Ju ,  Salman Kahn ,  Juwon Lee ,  Chad E. Germany ,  Alexander K. Zettl ,  Feng Wang ,  Michael F. Crommie

IPC分类号： H01L21/20 ,  H01L21/326 ,  H01L21/479 ,  H01L21/225 ,  H01L29/16 ,  H01L21/02

CPC分类号： H01L21/326 ,  H01L21/02381 ,  H01L21/02488 ,  H01L21/02502 ,  H01L21/02527 ,  H01L21/02568 ,  H01L21/2254 ,  H01L21/2256 ,  H01L21/479 ,  H01L22/14 ,  H01L29/1606

摘要： This disclosure provides systems, methods, and apparatus related to locally doping two-dimensional (2D) materials. In one aspect, an assembly including a substrate, a first insulator disposed on the substrate, a second insulator disposed on the first insulator, and a 2D material disposed on the second insulator is formed. A first voltage is applied between the 2D material and the substrate. With the first voltage applied between the 2D material and the substrate, a second voltage is applied between the 2D material and a probe positioned proximate the 2D material. The second voltage between the 2D material and the probe is removed. The first voltage between the 2D material and the substrate is removed. A portion of the 2D material proximate the probe when the second voltage was applied has a different electron density compared to a remainder of the 2D material.

摘要翻译： 本公开提供了与局部掺杂二维（2D）材料有关的系统，方法和装置。 在一个方面中，形成包括衬底，设置在衬底上的第一绝缘体，设置在第一绝缘体上的第二绝缘体和设置在第二绝缘体上的2D材料的组件。 在2D材料和衬底之间施加第一电压。 通过施加在2D材料和衬底之间的第一电压，在2D材料和位于2D材料附近的探针之间施加第二电压。 去除2D材料和探头之间的第二电压。 去除2D材料和衬底之间的第一电压。 当施加第二电压时，靠近探针的2D材料的一部分与2D材料的其余部分具有不同的电子密度。

公开(公告)号：US09364692B2

公开(公告)日：2016-06-14

申请号：US14269094

申请日：2014-05-03

申请人： Feng Wang ,  Wayne Li ,  Yunhua Hu

发明人： Feng Wang ,  Wayne Li ,  Yunhua Hu

IPC分类号： A62B1/22 ,  B64D25/00 ,  A62B1/02 ,  B64D17/00 ,  B64D1/14

CPC分类号： A62B1/22 ,  A62B1/02 ,  B64D1/14 ,  B64D17/00 ,  B64D25/00

摘要： An inflatable lifesaving device is designed to provide a user with an apparatus to escape a high rise building in emergency situations in a sufficiently rapid manner. It is simply composed of a hemisphere including a plurality of independent cell airbags, internal hoses, and check valves, a parachute integrated with the hemisphere, an air supply system, an external hose, a quick release hose coupler, a harness mounted on the body of the user, a connection rope that connects the harness to the inside of the building, a rope quick release to separate the connection rope, a descent rope, a backpack. To operate the inflatable lifesaving device, the user wearing the harness with the backpack exits a window or a balcony with the harness connected to the inside of the building through the connection rope with the release device. The air supply system is then turned on and high pressure air inflates and opens up the hemisphere and the parachute so that they are gradually formed from the back of the user to the front, and eventually the user is surrounded by them. after that, the external hose and the connection rope are released. As a result, the user will move down with the hemisphere and the parachute.

摘要翻译： 一种充气救生装置被设计成为用户提供一种在紧急情况下以足够快的方式逃离高层建筑物的装置。 它简单地由包括多个独立的电池安全气囊，内部软管和止回阀的半球组成，与半球集成的降落伞，空气供应系统，外部软管，快速释放软管联接器，安装在主体上的线束 用于将线束连接到建筑物内部的连接绳索，绳索快速释放以分离连接绳索，下降绳索，背包。 为了操作充气救生装置，用背包戴着线束的使用者通过带有释放装置的连接绳将出口通过连接到建筑物内部的线束离开窗户或阳台。 空气供给系统然后被打开，高压空气充气并打开半球和降落伞，使得它们从使用者的后部逐渐形成到前面，并且最终使用者被它们包围。 之后，外部软管和连接绳松开。 因此，用户将会与半球和降落伞一起向下移动。

公开(公告)号：US09354000B2

公开(公告)日：2016-05-31

申请号：US13463066

申请日：2012-05-03

申请人： Feng Wang ,  Jianlong Jiang ,  Xiaohui Wu ,  Qiang Gao ,  Linjie Huang

发明人： Feng Wang ,  Jianlong Jiang ,  Xiaohui Wu ,  Qiang Gao ,  Linjie Huang

IPC分类号： F28F13/06 ,  F24F13/08 ,  F28D1/04 ,  F28B1/06 ,  F28F17/00 ,  F28F9/22

CPC分类号： F28F13/06 ,  F24F13/08 ,  F28B1/06 ,  F28D1/0426 ,  F28D1/047 ,  F28F17/005 ,  F28F2009/222

摘要： A heat-exchange device comprises a first heat exchanger defining an upper end and a lower end. A second heat exchanger defines an upper end connected to the upper end of the first heat exchanger and a lower end spaced apart from the lower end of the first heat exchanger in a substantially longitudinal direction such that a predetermined angle between the first heat exchanger and second heat exchanger is between about 0 and 180°. A wind-guide member is disposed between the first heat exchanger and second heat exchanger for guiding wind toward the first heat exchanger and second heat exchanger.

摘要翻译： 热交换装置包括限定上端和下端的第一热交换器。 第二热交换器限定连接到第一热交换器的上端的上端和在第一热交换器的大致纵向方向上与第一热交换器的下端间隔开的下端，使得第一热交换器和第二热交换器之间的预定角度 热交换器在约0和180°之间。 导风构件设置在第一热交换器和第二热交换器之间，用于向第一热交换器和第二热交换器引导风。

公开(公告)号：US20150314142A1

公开(公告)日：2015-11-05

申请号：US14269094

申请日：2014-05-03

申请人： Feng Wang ,  Wayne Li ,  Yunhua Hu

发明人： Feng Wang ,  Wayne Li ,  Yunhua Hu

IPC分类号： A62B1/22 ,  B64D1/14 ,  B64D17/00 ,  B64D25/00 ,  A62B1/02

CPC分类号： A62B1/22 ,  A62B1/02 ,  B64D1/14 ,  B64D17/00 ,  B64D25/00

摘要： An inflatable lifesaving device is designed to provide a user with an apparatus to escape a high rise building in emergency situations in a sufficiently rapid manner. It is simply composed of a hemisphere including a plurality of independent cell airbags, internal hoses, and check valves, a parachute integrated with the hemisphere, an air supply system, an external hose, a quick release hose coupler, a harness mounted on the body of the user, a connection rope that connects the harness to the inside of the building, a rope quick release to separate the connection rope, a descent rope, a backpack. To operate the inflatable lifesaving device, the user wearing the harness with the backpack exits a window or a balcony with the harness connected to the inside of the building through the connection rope with the release device. The air supply system is then turned on and high pressure air inflates and opens up the hemisphere and the parachute so that they are gradually formed from the back of the user to the front, and eventually the user is surrounded by them. after that, the external hose and the connection rope are released. As a result, the user will move down with the hemisphere and the parachute.

摘要翻译： 一种充气救生装置被设计成为用户提供一种在紧急情况下以足够快的方式逃离高层建筑物的装置。 它简单地由包括多个独立的电池安全气囊，内部软管和止回阀的半球组成，与半球集成的降落伞，空气供应系统，外部软管，快速释放软管联接器，安装在主体上的线束 用于将线束连接到建筑物内部的连接绳索，绳索快速释放以分离连接绳索，下降绳索，背包。 为了操作充气救生装置，用背包戴着线束的使用者通过带有释放装置的连接绳将出口通过连接到建筑物内部的线束离开窗户或阳台。 空气供给系统然后被打开，高压空气充气并打开半球和降落伞，使得它们从使用者的后部逐渐形成到前面，并且最终使用者被它们包围。 之后，外部软管和连接绳松开。 因此，用户将会与半球和降落伞一起向下移动。

公开(公告)号：US08968453B2

公开(公告)日：2015-03-03

申请号：US13583282

申请日：2011-01-14

申请人： Xiaojun Peng ,  Tao Liu ,  Jinhe Wu ,  Rong Zhang ,  Jingyue Wang ,  Feng Wang ,  Shaolei Li ,  Jianzhou Zhang ,  Zhengru Yang

发明人： Xiaojun Peng ,  Tao Liu ,  Jinhe Wu ,  Rong Zhang ,  Jingyue Wang ,  Feng Wang ,  Shaolei Li ,  Jianzhou Zhang ,  Zhengru Yang

IPC分类号： C09D11/02 ,  C09B5/14 ,  C09D11/328 ,  C09D11/037 ,  C09B62/04 ,  C09B62/465 ,  C09B62/503

CPC分类号： C09D11/328 ,  C09B5/14 ,  C09B62/04 ,  C09B62/465 ,  C09B62/503 ,  C09D11/037

摘要： The present invention relates to a class of compounds of general formula (I) or their salts of general formula (II): In formula (I)-(II), the substituents (A)p and (SO3H)n on the benzene ring are at the ortho, meta or para position, n is 0-2, and p is 0-3; M is selected from Li+, Na+, K+, NH4+ or organic ammonium salt N+R1R2R3R4, where R1, R2, R3, R4 are the same or different H, C1-18 alkyl groups, cyclohexyl groups, CH2CH2OH, CH(CH3)CH2OH or benzyl groups; where p>0, A stands for the same or different groups selected from: H, CN, NO2, NH2, F, Cl, Br, C1-18 alkyl group, cyclohexyl group, phenyl group, benzyl group, phenoxy group, C1-18 alkoxy group, C1-18 alkylthio group, SO2CH═CH2, SO2CH2CH2A1, NR6COR5 or NR6SO2R5.

摘要翻译： 本发明涉及一类通式（I）的化合物或其通式（Ⅱ）的盐：在式（I） - （II）中，苯环上的取代基（A）p和（SO 3 H）n 在邻位，间位或对位，n为0-2，p为0-3; M选自Li +，Na +，K +，NH4 +或有机铵盐N + R1R2R3R4，其中R1，R2，R3，R4是相同或不同的H，C1-18烷基，环己基，CH2CH2OH，CH（CH3）CH2OH 或苄基; 其中p> 0，A代表选自以下的相同或不同的基团：H，CN，NO 2，NH 2，F，Cl，Br，C 1-18烷基，环己基，苯基，苄基，苯氧基， 18烷氧基，C1-18烷硫基，SO2CH = CH2，SO2CH2CH2A1，NR6COR5或NR6SO2R5。

公开(公告)号：US08849924B2

公开(公告)日：2014-09-30

申请号：US12756230

申请日：2010-04-08

申请人： Sanjay H. Ramaswamy ,  GuangSheng Bao ,  Yingtao Dong ,  Yun-Rui SiMa ,  Feng Wang

发明人： Sanjay H. Ramaswamy ,  GuangSheng Bao ,  Yingtao Dong ,  Yun-Rui SiMa ,  Feng Wang

IPC分类号： G06F15/16 ,  H04L29/08 ,  H04L12/24 ,  H04L12/751

CPC分类号： H04L29/08315 ,  H04L41/082 ,  H04L41/12 ,  H04L41/20 ,  H04L41/22 ,  H04L41/5058 ,  H04L45/02

摘要： Network infrastructure management may be provided. First, administrative tools associated with a plurality of network topologies may be provided in a management console. Providing the administrative tools may comprise providing a first set of tools associated with a first network topology in the console. The first network topology may be an on-premises topology. Providing the administrative tools may also comprise providing a second set of tools associated with a second network topology in the console. The second network topology may be a cloud topology. Next, communications for the plurality of network topologies may be established to manage the plurality of network topologies through the management console. Establishing the communications for the plurality of network topologies may comprise establishing a first communications channel between the first network topology and the console. In addition, establishing the communications may comprise establishing a second communications channel between the second network topology.

摘要翻译： 可以提供网络基础架构管理。 首先，可以在管理控制台中提供与多个网络拓扑结构相关联的管理工具。 提供管理工具可以包括提供与控制台中的第一网络拓扑相关联的第一组工具。 第一个网络拓扑可以是本地拓扑。 提供管理工具还可以包括提供与控制台中的第二网络拓扑相关联的第二组工具。 第二个网络拓扑可以是云拓扑。 接下来，可以建立用于多个网络拓扑的通信，以通过管理控制台管理多个网络拓扑。 建立用于多个网络拓扑的通信可以包括在第一网络拓扑和控制台之间建立第一通信信道。 此外，建立通信可以包括在第二网络拓扑之间建立第二通信信道。

公开(公告)号：US20140146660A1

公开(公告)日：2014-05-29

申请号：US14131200

申请日：2012-07-30

申请人： Feng Wang

发明人： Feng Wang

IPC分类号： H04L12/707

CPC分类号： H04L45/22 ,  H04L41/0672

摘要： A method and a network device for preventing service disruption during a restart of a line card. The line card including a CPU control system and a forwarding system. Information on the CPU control system is stored in a predetermined storage and a flag is set prior to the restart of the line card. The stored information includes configuration information of the forwarding system and protocol state information of the CPU control system. The CPU control system is restarted while the forwarding system is maintained in a state of providing forwarding service. Upon detecting the flag is set during the restart of the CPU control system, the stored information is restored on the CPU control system.

摘要翻译： 一种用于在线卡重启期间防止服务中断的方法和网络设备。 线卡包括CPU控制系统和转发系统。 关于CPU控制系统的信息存储在预定的存储器中，并且在线卡的重新启动之前设置了标志。 所存储的信息包括转发系统的配置信息和CPU控制系统的协议状态信息。 当转发系统处于提供转发服务的状态时，重新启动CPU控制系统。 在CPU控制系统重新启动时检测到标志被置位时，CPU控制系统上恢复存储的信息。