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    Object separating
    43.
    发明授权
    Object separating 有权

    公开(公告)号：US11554377B2

    公开(公告)日：2023-01-17

    申请号：US16606869

    申请日：2018-01-29

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Viktor Shkolnikov ,  Daixi Xin

    IPC: B03C5/02 ,  B01D17/06

    Abstract: An object separator may include a substrate, a fluid channel supported by the substrate, a pair of electrodes along the fluid channel to form a dielectrophoretic force to interact with an object entrained in a fluid and an inertial pump supported by the substrate to move the fluid along the fluid channel.

    Three dimensional volume imaging
    45.
    发明授权
    Three dimensional volume imaging 有权

    公开(公告)号：US11481964B2

    公开(公告)日：2022-10-25

    申请号：US16605949

    申请日：2018-04-27

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Yang Lei ,  Viktor Shkolnikov ,  Daixi Xin

    IPC: G06T15/00 ,  G06T15/20 ,  G06T17/00

    Abstract: A three-dimensional volume modeling method may include rotating a three-dimensional biological object having a translucent outer surface to different angular positions, capturing different two-dimensional images of the three-dimensional biological object, each of the different two-dimensional images being at a different angular position, and modeling an exterior of the three-dimensional biological object based upon the different two-dimensional images. The method may further involve identifying a point of an internal structure of the three-dimensional biological object each of the two-dimensional images and modeling the internal structure of the three-dimensional biological object in three-dimensional space relative to the exterior of the three-dimensional biological object by triangulating the point amongst the different two-dimensional images using a three-dimensional volumetric template of the three-dimensional biological object.

    CELL TRAPPING ARRAYS WITH SELECTIVE EJECTION
    46.
    发明申请
    CELL TRAPPING ARRAYS WITH SELECTIVE EJECTION 有权

    公开(公告)号：US20220143594A1

    公开(公告)日：2022-05-12

    申请号：US17415161

    申请日：2019-07-25

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Alexander Govyadinov ,  Viktor Shkolnikov

    IPC: B01L3/02 ,  B01L3/00 ,  G01N15/14

    Abstract: In example implementations, a cell trapping array is provided. The cell trapping array includes a plurality of plates coupled along adjacent edges to form a channel. A plurality of orifices are formed in a first plate of the plurality of plates of the channel. The plurality of orifices is shaped to create a meniscus of a fluid in the channel in the plurality of orifices that is to attract a single cell from cells flowing through the channel in the fluid. The cell trapping array includes a selective ejection system coupled to a second plate located opposite the first plate of the channel. The selective ejection system is to selectively eject the single cell from one of the plurality of orifices.

    BLOOD CIRCULATION FOR CULTURE GROWTH
    47.
    发明申请
    BLOOD CIRCULATION FOR CULTURE GROWTH 有权

    公开(公告)号：US20220081667A1

    公开(公告)日：2022-03-17

    申请号：US17420040

    申请日：2019-01-18

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Milo Overbay ,  Viktor Shkolnikov

    IPC: C12M1/00 ,  C12M1/34 ,  C12M1/36

    Abstract: Blood being circulated to mimic the environment it naturally inhabits increases growth of cultures including bacteria for analysis. The present disclosure presents examples of a device, method, computer-readable medium, and other techniques for simulating a natural environment for blood. The techniques may include a channel with a hydrophobic interior surface and a fluid mover to encourage continuous fluid flow through the channel. The techniques may further include a gas exchange opening of the channel that exposes a fluid to gas outside of the channel.

    CELL MARKING SYSTEMS
    49.
    发明申请
    CELL MARKING SYSTEMS 有权

    公开(公告)号：US20220072550A1

    公开(公告)日：2022-03-10

    申请号：US17417344

    申请日：2019-02-01

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Alexander Govyadinov ,  Viktor Shkolnikov

    IPC: B01L3/00

    Abstract: In one example in accordance with the present disclosure, a cell marking system is described. The cell marking system includes a microfluidic channel to serially feed individual cells from a volume of cells into at least one marking chamber. The at least one marking chambers hold an individual cell to be marked. The cell marking system also includes a marker application device per marking chamber to selectively apply a marker to the individual cell disposed within a respective marking chamber.

    Nucleic acid separation
    50.
    发明授权
    Nucleic acid separation 有权

    公开(公告)号：US11253857B2

    公开(公告)日：2022-02-22

    申请号：US16605927

    申请日：2018-03-27

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Viktor Shkolnikov ,  Alexander Govyadinov

    IPC: B01L3/00 ,  B01L7/00

    Abstract: An example system includes an input channel to flow nucleic segments therethrough, a mixing portion coupled to the input channel, a separation chamber in fluid communication with the second end of the input channel, at least two output channels coupled to the chamber, and an integrated pump to facilitate flow through the separation chamber. The mixing portion is to include at least two different categories of beads having different sizes from each other and having a probe to attach to a corresponding nucleic acid segment. The separation chamber has a passive separation structure including an array of columns spaced apart to facilitate separation of the different categories of beads and attached corresponding nucleic acid segment into at least two flow paths based on a size of the category of the beads. Each output channel is to receive separated categories of beads and attached nucleic acid segments.

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