Boxazomycin A and B, new antibiotics containing benzoxazole nucleus
    41.
    发明授权
    Boxazomycin A and B, new antibiotics containing benzoxazole nucleus 失效
    苯唑霉素A和B,含有苯并恶唑核的新型抗生素

    公开(公告)号:US4728612A

    公开(公告)日:1988-03-01

    申请号:US889525

    申请日:1986-07-25

    IPC分类号: C07D413/04 C12P17/16 C12N1/20

    摘要: The novel antibiotics boxazomycin A and B, which have the formula: ##STR1## wherein R is --CH.sub.2 OH for boxazomycin A; and R is --CH.sub.3 for boxazomycin B. These new antibiotics, which are produced by cultivating a novel strain of Pseudonocardia (ATCC 53205), inhibit growth of aerobic Gram-positive bacteria and anaerobes with enhanced activity observed in acidic medium.

    摘要翻译: 所述新型抗生素扑西他霉素A和B具有以下结构式:其中R为苯甲酰霉素A的-CH 2 OH; 并且对于烟曲霉素B,R是-CH 3。通过培养新的假诺卡氏菌菌株(ATCC 53205)产生的这些新的抗生素抑制在酸性介质中观察到增强活性的需氧革兰氏阳性菌和厌氧菌的生长。