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    Stable three-phased emulsions
    44.
    发明授权
    Stable three-phased emulsions 有权
    稳定的三相乳液

    公开(公告)号：US08691248B2

    公开(公告)日：2014-04-08

    申请号：US12253624

    申请日：2008-10-17

    申请人： Amit Patel

    发明人： Amit Patel

    IPC分类号： A61K8/60 ,  A61K8/06 ,  A61K47/08

    CPC分类号： A61K8/064 ,  A61K8/066 ,  A61K8/585 ,  A61K8/73 ,  A61K8/891 ,  A61K8/895 ,  A61K9/0014 ,  A61K47/24 ,  A61K47/36 ,  A61K2800/30 ,  A61K2800/49 ,  A61K2800/596 ,  A61Q1/02 ,  A61Q1/12 ,  A61Q19/00 ,  A61Q19/008 ,  B01F17/0071

    摘要： Disclosed is a three-phase emulsion comprising an aqueous-gel outer phase; and a water-in-oil inner phase, wherein the emulsion is stable. The aqueous-gel outer phase can include 10% to 50% by weight of the total weight of the emulsion. This phase can also include 70% to 95% by weight of water based on the total weight of the aqueous-gel outer phase, a gelling agent, and an emulsifier having a hydrophilic-lipophilic balance (HLB) value of 10 to 19. The water-in-oil inner phase can include 50% to 95% by weight based on the total weight of the three-phase emulsion. This phase can also include 50% to 80% by weight of water based on the total weight of the water-in-oil inner phase, 20% to 50% by weight of oil based on the total weight of the water-in-oil inner phase, and an emulsifier.

    摘要翻译： 公开了包含水凝胶外相的三相乳液; 和油包水内相，其中乳液是稳定的。 水凝胶外相可以包含乳液总重量的10重量％至50重量％。 基于水性凝胶外相的总重量，胶凝剂和亲水亲油平衡（HLB）值为10〜19的乳化剂，该相也可以包含70〜95重量％的水。 油包水内相可以包含基于三相乳液的总重量的50重量％至95重量％。 该相还可以包括基于油包水内相的总重量的50重量％至80重量％的水，基于油包水的总重量为20重量％至50重量％的油 内相和乳化剂。

    QUANTIFICATION OF CIRCULATING STEM AND PROGENITOR CELLS AS A MEANS OF ASSESSING EFFICACY OF NATUROPATHIC INTERVENTIONS
    46.
    发明申请
    QUANTIFICATION OF CIRCULATING STEM AND PROGENITOR CELLS AS A MEANS OF ASSESSING EFFICACY OF NATUROPATHIC INTERVENTIONS 审中-公开
    循环干细胞和祖细胞的定量作为评估自然疗法干预效果的手段

    公开(公告)号：US20130252257A1

    公开(公告)日：2013-09-26

    申请号：US13621702

    申请日：2012-09-17

    申请人： Amit Patel ,  Annette M. Marleau

    发明人： Amit Patel ,  Annette M. Marleau

    IPC分类号： G01N33/569

    CPC分类号： G01N33/56966

    摘要： Disclosed are tests, correlations and “theranostic” interventions aimed at optimizing general health through quantification of cells with regenerative potential in circulation. Some embodiments include use of circulating endothelial progenitor cell (EPC) testing as a means of quantifying general health status in a patient. The combination of EPC testing together with a naturopathic intervention, wherein the selection and dosage of said naturopathic intervention is tailored based on said quantitative test is provided. In other embodiments, regenerative cells are selected from the group comprising of very small embryonic like cells (VSEL), CD34 cells with hematopoietic potential, and circulating mesenchymal stem cells (MSC). Naturopathic interventions include recommendations of lifestyle modification, dietary supplements, intravenous vitamins, detoxification, acupuncture, and guided imagery.

    摘要翻译： 公开了旨在通过定量循环中具有再生潜力的细胞来优化总体健康的测试，相关性和“神经性”干预。 一些实施方案包括使用循环内皮祖细胞（EPC）测试作为量化患者的一般健康状况的手段。 提供EPC测试与自然疗法干预的组合，其中基于所述定量测试定制所述自然疗法干预的选择和剂量。 在其他实施方案中，再生细胞选自非常小的胚胎样细胞（VSEL），具有造血潜能的CD34细胞和循环间充质干细胞（MSC）的组。 自然疗法干预措施包括改善生活方式的建议，膳食补充剂，静脉注射维生素，解毒，针灸和引导图像。

    METHODS AND COMPOSITIONS FOR THE CLINICAL DERIVATION OF AN ALLOGENIC CELL AND THERAPEUTIC USES
    47.
    发明申请
    METHODS AND COMPOSITIONS FOR THE CLINICAL DERIVATION OF AN ALLOGENIC CELL AND THERAPEUTIC USES 审中-公开
    用于临床衍生的同种异体细胞和治疗用途的方法和组合物

    公开(公告)号：US20130216505A1

    公开(公告)日：2013-08-22

    申请号：US13732204

    申请日：2012-12-31

    申请人： Amit Patel

    发明人： Amit Patel

    IPC分类号： C12N5/071 ,  A61K35/48

    CPC分类号： C12N5/0682 ,  A61K35/51 ,  C12N5/0605 ,  C12N5/0653 ,  C12N5/0654 ,  C12N5/0655 ,  C12N5/0657 ,  C12N5/0665

    摘要： Various cells, stem cells, and stem cell components, including associated methods of generating and using such cells are provided. In one aspect, for example, an isolated cell that is capable of self-renewal and culture expansion and is obtained from a subepithelial layer of a mammalian umbilical cord tissue. Such an isolated cell expresses at least three cell markers selected from CD29, CD73, CD90, CD166, SSEA4, CD9, CD44, CD146, or CD105, and does not express at least three cell markers selected from CD45, CD34, CD14, CD79, CD106, CD86, CD80, CD19, CD117, Stro-1, or HLA-DR.

    摘要翻译： 提供了各种细胞，干细胞和干细胞组分，包括产生和使用这些细胞的相关方法。 在一个方面，例如，能够进行自我更新和培养扩增并从哺乳动物脐带组织的上皮下层获得的分离的细胞。 这样的分离的细胞表达选自CD29，CD73，CD90，CD166，SSEA4，CD9，CD44，CD146或CD105的至少三种细胞标志物，并且不表达选自CD45，CD34，CD14，CD79， CD106，CD86，CD80，CD19，CD117，Stro-1或HLA-DR。

    Adjusting ad costs using document performance or document collection performance
    48.
    发明授权
    Adjusting ad costs using document performance or document collection performance 有权
    使用文档性能或文档收集性能调整广告费用

    公开(公告)号：US08494900B2

    公开(公告)日：2013-07-23

    申请号：US10880972

    申请日：2004-06-30

    申请人： Brian Axe ,  Doug Beeferman ,  Amit Patel ,  Nathan Stoll ,  Hal Varian

    发明人： Brian Axe ,  Doug Beeferman ,  Amit Patel ,  Nathan Stoll ,  Hal Varian

    IPC分类号： G06Q30/00

    CPC分类号： G06Q30/0275 ,  G06Q30/02 ,  G06Q30/0247 ,  G06Q30/0273

    摘要： Documents or document sets may be scored to reflect a value of an action, such as a selection for example, when an ad is served with the document (or a document belonging to a document set). A cost associated with the action with respect to an ad that was served with a document may then be adjusted using the score. For example, ad scores may be accepted or determined, and a document may be scored using the ad scores when served with the document and ad scores across a collection of documents to generate a document score. Each of the ad scores may indicate a value of an action with respect to an ad, such as a conversion rate, or a return on investment for an ad selection for example. Document scores used in this way may help advertisers get a more consistent cost per conversion, or return on investment, without requiring them to enter and manage various offers for various documents and/or various ad serving systems having various conversion rates or returns on investment.

    摘要翻译： 可以对文档或文档集进行评分，以反映动作的价值，例如当向文档（或属于文档集合的文档）投放广告时的选择。 然后可以使用分数调整与为文档提供的广告相关的操作费用。 例如，可以接受或确定广告得分，并且当通过文档集合提供的广告分数和文档集合中的广告分数来生成文档分数时，可以使用广告分数来评分文档。 每个广告分数可以指示关于广告的动作的值，例如转化率，或者例如广告选择的投资回报率。 以这种方式使用的文档分数可以帮助广告客户获得更加一致的每次转化成本或投资回报，而不需要他们输入和管理各种文档和/或具有各种转换率或投资回报的各种广告服务系统的各种报价。