公开(公告)号：US5496359A

公开(公告)日：1996-03-05

申请号：US112587

申请日：1993-08-26

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： A61F2/00 ,  A61F2/06 ,  A61F2/30 ,  A61F2/38 ,  A61L27/04 ,  A61L27/30 ,  A61L27/50 ,  A61L29/10 ,  A61L31/02 ,  A61L31/08 ,  A61L33/02 ,  A61M1/10 ,  A61N1/04

CPC分类号： A61L27/306 ,  A61F2/0077 ,  A61F2/06 ,  A61F2/30767 ,  A61L27/047 ,  A61L27/507 ,  A61L29/106 ,  A61L31/022 ,  A61L31/088 ,  A61L33/027 ,  A61M1/10 ,  A61F2/38 ,  A61F2/958 ,  A61F2002/30107 ,  A61F2210/0009 ,  A61F2310/00089 ,  A61F2310/00634 ,  A61F2310/00892

摘要： Cardiovascular, vascular, and percutaneous implants, as well as catheters and other surgical instruments, fabricated from a core or substrate of a low modulus metal coated with blue to black zirconium oxide or zirconium nitride. The coating provides enhanced thrombogenicity, biocompatibility, blood compatibility, corrosion-resistance, friction and microfretting resistance, durability, and electrical insulation, where applicable. The coatings may be applied to low modulus metallic substrates by physical or chemical vapor deposition as well as other ion-beam assisted methods. Preferably, however, for optimizing attachment strength, the implants and surgical instruments are fabricated from zirconium or zirconium-containing alloys and the coatings are formed by oxidizing or nitriding through an in situ method that develops a coating from and on the metal surface of the implant or instrument, without need for depositing a coating on the metal surface.

摘要翻译： 由涂覆有蓝色至黑色氧化锆或氮化锆的低模量金属的芯或基底制成的心血管，血管和经皮植入物以及导管和其它手术器械。 如果适用，涂层可提供增强的血栓形成，生物相容性，血液相容性，耐腐蚀性，摩擦力和抗微生物抗性，耐久性和电绝缘性。 涂层可以通过物理或化学气相沉积以及其他离子束辅助方法施加到低模量金属基底上。 然而，优选地，为了优化附着强度，植入物和手术器械由含锆或锆的合金制成，并且涂层通过原位方法氧化或氮化形成，该方法从植入物的金属表面上形成涂层 或仪器，而不需要在金属表面上沉积涂层。

公开(公告)号：US5415704A

公开(公告)日：1995-05-16

申请号：US120287

申请日：1993-09-13

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： A61F2/00 ,  A61F2/24 ,  A61F2/30 ,  A61L27/04 ,  A61L27/06 ,  A61L27/30 ,  A61F2/02 ,  C22C14/00

CPC分类号： A61L27/306 ,  A61F2/30767 ,  A61L27/045 ,  A61L27/06 ,  A61F2002/30922 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00089 ,  A61F2310/00598 ,  A61F2310/00856

摘要： This invention provides surface hardened, abrasion resistant high strength, biocompatible metal medical implants, in particular, titanium alloy implants which do not include any elements which have been shown or suggested as having short term or long term potential adverse effect from a standpoint of biocompatibility. Further, the invention provides methods of strengthening and hardening the surfaces of other titanium, zirconium, and cobalt-based alloy implants with small concentrations of a metal solute such as zirconium, yttrium, tantalum, aluminum, silicon, chromium, or thorium via internal oxidation or nitridation. Alternatively, nitrogen, oxygen, or carbon can be diffused directly into the surface of the implants by interstitial hardening to further increase the surface abrasion resistance of these internally oxidized or internally nitridized implant metal or metal alloys.

摘要翻译： 本发明提供了表面硬化，耐磨损的高强度，生物相容性金属医疗植入物，特别是钛合金植入物，其不包括从生物相容性的角度已被显示或建议为具有短期或长期潜在不利影响的任何元素。 此外，本发明提供了通过内部氧化来强化和硬化具有小浓度的金属溶质如锆，钇，钽，铝，硅，铬或钍的其它钛，锆和钴基合金植入物的表面的方法 或氮化。 或者，氮，氧或碳可以通过间隙硬化直接扩散到植入物的表面，以进一步提高这些内部氧化或内部氮化的植入金属或金属合金的表面耐磨性。

公开(公告)号：US5370694A

公开(公告)日：1994-12-06

申请号：US5621

申请日：1993-01-19

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： A61F2/00 ,  A61F2/06 ,  A61F2/30 ,  A61F2/36 ,  A61F2/38 ,  A61F2/40 ,  A61F2/42 ,  A61F2/44 ,  A61F2/46 ,  A61L27/04 ,  A61L27/30 ,  A61L29/10 ,  A61L31/02 ,  A61L31/08 ,  A61L33/02 ,  A61F2/28 ,  A61F2/32

CPC分类号： A61F2/0077 ,  A61F2/06 ,  A61F2/30767 ,  A61F2/3609 ,  A61F2/40 ,  A61L27/047 ,  A61L27/306 ,  A61L29/106 ,  A61L31/022 ,  A61L31/088 ,  A61L33/027 ,  A61F2/38 ,  A61F2/3804 ,  A61F2/4059 ,  A61F2/4081 ,  A61F2/44 ,  A61F2002/30084 ,  A61F2002/30107 ,  A61F2002/30474 ,  A61F2002/30902 ,  A61F2002/365 ,  A61F2002/368 ,  A61F2002/4018 ,  A61F2002/4243 ,  A61F2210/0009 ,  A61F2220/0025 ,  A61F2310/00089 ,  A61F2310/00634 ,  A61F2310/00892

摘要： Medical implants of zirconium or zirconium-based alloy coated with blue or blue-black zirconium oxide or zirconium nitride to provide low friction, highly wear resistant coatings especially useful in hemiarthroplasty applications such as unipolar artificial joints, including unipolar hip joints or surface replacements, knee joints, shoulder joints, elbows, spinal segments, fingers, etc. The zirconium oxide or nitride coated prostheses also provide a barrier against implant corrosion caused by galvanic coupling with other metal components or in vivo ionization of the metal prosthesis.

摘要翻译： 涂覆有蓝色或蓝黑色氧化锆或氮化锆的锆或锆基合金的医疗植入物，以提供低摩擦，高度耐磨的涂层，特别适用于半关节成形术应用，如单极人工关节，包括单极髋关节或表面置换，膝盖 关节，肩关节，肘部，脊髓节段，手指等。氧化锆或氮化物涂覆的假体还提供了抵抗由与其他金属组分的电偶耦合引起的植入物腐蚀或金属假体的体内电离的屏障。

公开(公告)号：US5282850A

公开(公告)日：1994-02-01

申请号：US919932

申请日：1992-07-27

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： A61F2/00 ,  A61F2/06 ,  A61F2/30 ,  A61F2/38 ,  A61L27/04 ,  A61L27/30 ,  A61L27/50 ,  A61L29/10 ,  A61L31/02 ,  A61L31/08 ,  A61L33/02 ,  A61M1/10 ,  A61F2/02 ,  A01N1/02 ,  A61J1/05

CPC分类号： A61F2/30767 ,  A61F2/0077 ,  A61F2/06 ,  A61L27/047 ,  A61L27/306 ,  A61L27/507 ,  A61L29/106 ,  A61L31/022 ,  A61L31/088 ,  A61L33/027 ,  A61M1/10 ,  A61F2/38 ,  A61F2/958 ,  A61F2002/30107 ,  A61F2210/0009 ,  A61F2310/00089 ,  A61F2310/00634 ,  A61F2310/00892

摘要： The invention provides hard, wear resistant, biocompatible and blood compatible coatings for components of ventricular assist, external mechanical heart and blood flow assist devices and total heart implants that are exposed to conditions of wear in the body and that may be exposed to blood components. The components are fabricated from zirconium or the alloys of zirconium and the coatings comprise either blue-black or black zirconium oxide or zirconium nitride that are tightly adhered to the underlying metal substrate. In the event that the component is used under conditions which subject it to wear, then the coating should have a thickness that provides sufficient residual compressive stresses to withstand these conditions.

摘要翻译： 本发明提供用于心室辅助，外部机械心脏和血流辅助装置以及暴露于体内磨损状况并且可能暴露于血液成分的总心脏植入物的组分的硬，耐磨，生物相容性和血液相容性涂层。 组分由锆或锆的合金制成，并且涂层包括牢固粘附在下面的金属基底上的蓝黑色或黑色氧化锆或氮化锆。 如果组件在使其磨损的条件下使用，则涂层应具有提供足够的残余压应力以承受这些条件的厚度。

公开(公告)号：US5192330A

公开(公告)日：1993-03-09

申请号：US740723

申请日：1991-08-06

申请人： Fu-Kuo Chang ,  Kenneth Reifsnider ,  James A. Davidson ,  Frederick S. Georgette

发明人： Fu-Kuo Chang ,  Kenneth Reifsnider ,  James A. Davidson ,  Frederick S. Georgette

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61F2/36 ,  A61L27/44 ,  B29C70/46 ,  B29D99/00

CPC分类号： B29D99/0007 ,  A61F2/30965 ,  A61F2/36 ,  A61L27/443 ,  B29C70/46 ,  A61F2/3094 ,  A61F2002/30009 ,  A61F2002/3686 ,  A61F2250/0028 ,  B29L2031/7532

摘要： Orthopedic device of biocompatible polymer with oriented fiber reinforcement. There is provided a device such as a hip stem which has a longitudinally curved body. The reinforcing fibers are continuous filament fiber plies with parallel orienated fibers in each ply. The plies are curved longitudinally to approximately correspond to the curve of the body. In one embodiment, there are longitudinally oriented fiber plies at or near the surfaces of the device and plies with fibers offset at 5.degree.-40.degree. from the longitudinal axis between the surface layers. The fiber orientation is balanced by providing a ply of negatively angled offset fibers of a similar angle for each positively angled offset ply. The device is made by molding plies preimpregnated with polymer (prepregs) simultaneously, by molding a plurality of prepregs into segments which are then molded together, or by molding a segment and incrementally molding additional layers of prepregs thereto in a series of progressively larger molds.

摘要翻译： 具有定向纤维增强的生物相容性聚合物的矫形装置。 提供了具有纵向弯曲体的诸如髋部杆的装置。 增强纤维是在每个层中具有平行疏散纤维的连续长丝纤维层。 帘布层纵向弯曲成大致对应于身体的曲线。 在一个实施例中，在装置的表面处或附近存在纵向定向的纤维层，并且纤维在表面层之间的纵向轴线偏离5°-40°。 通过为每个成角度的偏移层提供具有相似角度的负角偏移光纤的层，来平衡纤维取向。 该装置是通过将多个预浸料坯模制成一起模制成段，然后通过模制一段并逐渐模制附加的一层预浸料到一系列逐渐变大的模具中，同时将聚合物（预浸料坯）预先浸渍的层压成型而成的。

公开(公告)号：US5064439A

公开(公告)日：1991-11-12

申请号：US5091

申请日：1987-01-20

申请人： Fu-Kuo Chang ,  Kenneth Reifsnider ,  James A. Davidson ,  Frederick S. Georgette

发明人： Fu-Kuo Chang ,  Kenneth Reifsnider ,  James A. Davidson ,  Frederick S. Georgette

IPC分类号： A61F2/02 ,  A61F2/00 ,  A61F2/30 ,  A61F2/36 ,  A61L27/00 ,  A61L27/44 ,  B29C70/46 ,  B29D99/00 ,  B32B27/12

CPC分类号： B29D99/0007 ,  A61F2/30965 ,  A61F2/36 ,  A61L27/443 ,  B29C70/46 ,  A61F2/3094 ,  A61F2002/30009 ,  A61F2002/3686 ,  A61F2250/0028 ,  B29L2031/7532 ,  Y10S623/911

摘要： Orthopedic device of biocompatible polymer with oriented fiber reinforcement. There is provided a device such as a hip stem which has a longitudinally curved body. The reinforcing fibers are continuous filament fiber plies with parallel oriented fibers in each ply. The plies are curved longitudinally to approximately correspond to the curve of the body. In one embodiment, there are longitudinally oriented fiber plies at or near the surfaces of the device and plies with fibers offset at 5.degree.-40.degree. from the longitudinal axis between the surface layers. The fiber orientation is balanced by providing a ply of negatively angled offset fibers of a similar angle for each positively angled offset ply. The device is made by molding plies preimpregnated with polymer (prepregs) simultaneously, by molding a plurality of prepregs into segments which are then molded together, or by molding a segment and incrementally molding additional layers of prepregs thereto in a series of progressively larger molds.

公开(公告)号：US4745833A

公开(公告)日：1988-05-24

申请号：US40850

申请日：1987-04-20

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： B26D1/30 ,  B26D5/42 ,  B26D7/01 ,  B26F1/38

CPC分类号： B26F1/3853 ,  B26D1/305 ,  B26D5/42 ,  B26D7/015 ,  Y10T83/576 ,  Y10T83/7507 ,  Y10T83/7513 ,  Y10T83/758 ,  Y10T83/817 ,  Y10T83/8743 ,  Y10T83/8799 ,  Y10T83/8805 ,  Y10T83/8828

摘要： Frame members of the apparatus mount cutter assemblies that are aligned by relative adjustive movement of the frame members with edges of a cutout that is to be cut from sheet material. The adjustive relative movement of the frame members additionally effects adjustment of the relative positions of the cutter assemblies and associated cam members also carried by the frame members. This in turn causes the cuts made by the cutter assemblies to be of the same length as the therewith aligned cutout edges. The apparatus preferably further includes clamping members that engages the sheet material during each cutting operation, and drive components for imparting desired motions to the various movable components of the apparatus.

摘要翻译： 装置安装刀具组件的框架构件，其通过框架构件与要从片材切割的切口的边缘的相对调节运动对准。 框架构件的调节相对运动另外实现了由框架构件承载的切割器组件和相关联的凸轮构件的相对位置的调整。 这又导致由切割器组件制成的切口与其对准的切口边缘具有相同的长度。 该装置优选地还包括在每个切割操作期间接合片材的夹紧构件以及用于将期望的运动传递给装置的各种可移动部件的驱动部件。

公开(公告)号：US08986374B2

公开(公告)日：2015-03-24

申请号：US13104648

申请日：2011-05-10

申请人： Hengchu Cao ,  Brian Conklin ,  Paul Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

发明人： Hengchu Cao ,  Brian Conklin ,  Paul Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415

摘要： Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

摘要翻译： 公开的假体瓣膜可以包括构造成将瓣膜固定到植入部位的缝合环。 一些公开的阀包括具有中性构型和折叠展开构型的弹性可折叠框架。 当从折叠部署配置释放时，一些公开的框架可以自扩展到中立配置。 折叠所公开的阀可以方便地进入缝合环，例如用于将瓣膜固定到植入部位，以及通过相对较小的手术切口插入瓣膜。

公开(公告)号：US20110276128A1

公开(公告)日：2011-11-10

申请号：US13104648

申请日：2011-05-10

申请人： Hengchu Cao ,  Brian Conklin ,  Paul Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

发明人： Hengchu Cao ,  Brian Conklin ,  Paul Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415

摘要： Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

摘要翻译： 公开的假体瓣膜可以包括构造成将瓣膜固定到植入部位的缝合环。 一些公开的阀包括具有中性构型和折叠展开构型的弹性可折叠框架。 当从折叠部署配置释放时，一些公开的框架可以自扩展到中立配置。 折叠所公开的阀可以方便地进入缝合环，例如用于将瓣膜固定到植入部位，以及通过相对较小的手术切口插入瓣膜。

公开(公告)号：US06443730B1

公开(公告)日：2002-09-03

申请号：US09870263

申请日：2001-05-30

申请人： James A. Davidson

发明人： James A. Davidson

IPC分类号： A61C502

摘要： A break-resistant composite comprising a plurality of fibers at least partially embedded in a polymer matrix forms a composite for making at least a portion of an endodonic instrument. At least a portion of the fibers are selected from a group consisting of partially twisted fibers and off-axis oriented fibers. The composite instrument can contain abrasive particulates to improve cutting and wear resistance for use in root canal procedures. The twisted fiber composite material allows for applied torque load response, improved flexibility within the root canal, and reduces or eliminates gross breakage of the instrument during use. The inventive composite can be molded or machined to make an endodnic instrument having certain desired diameters, tapers, helical recesses, and other design features.