摘要:
The present invention is a compound and pharmaceutical composition comprising a compound of formula (I): wherein R1 is a 4-(lower) alkyl-imidazol-1-yl or a 4,5-di(lower) alkyl-imidazol-1-yl group, R2 is a hydrogen atom or a lower alkyl group, and R3 is a fluorenyl group. The compound of formula (I) includes pharmaceutically acceptable salts: The compound of formula (I) and salts thereof have 5-HT antagonism activity.
摘要:
A piperazine compound of the formula: ##STR1## wherein: X is carbonyl or sulfonyl; Y is a direct bond or lower alkylene; and R.sub.1, R.sub.2, R.sub.3, R.sub.4 are as defined herein. The compounds are advantageously used as Tachykinin antagonists in the treatment of respiratory diseases, ophthalmic diseases and inflammatory diseases, for example.
摘要:
A first carrier signal generator (15) generates a carrier signal (S1) at a first frequency to modulate a preset identification code (S). A second carrier signal generator (16) generates a carrier signal (S2) at a second frequency, distinct from the first frequency. A modulator (14) affixes the identification code (S) to the carrier signal (S2), and outputs the carrier signal (S2) to a light-emitting circuit (17). When a "smart" or "learning" remote controller, of the type that demodulates frequency, receives the identification code (S), the carrier signal (Sw) of the second frequency is demodulated at the first frequency, compressed and stored in memory. The carrier signal (S2) set at the second frequency can cause the memory capacity of the remote controller to overflow, thereby preventing the identification code (S) from being stored in the learning remote controller.
摘要:
A television signal and ATM cell switching system for switching ATM cells of data other than television signals and for supplying one channel among a plurality of channels of television signals transmitted from a source to a subscriber to carry out one-way communication of the television signals from the source to the subscribers and two-way communication of the data other than the television signals between the network and the subscribers comprising, a television signal transmitting unit for transmitting television signals in the form of ATM cells, an ATM switching unit for switching ATM cell data other than the television signals, a television signal cell inserting circuit for receiving a plurality of channels of the television signals from the television signal transmitting unit, and for receiving ATM cell data other than the television signals after being switched by the ATM switching unit, the television signal inserting circuit comprising, a demultiplexing circuit for demultiplexing the output of the ATM switching unit to provide a plurality of outputs corresponding to respective subscribers, and a plurality of multiplexing circuits each for multiplexing the demultiplexed ATM cell received from one corresponding output of the demultiplexing circuit and one channel of the ATM cells selected in accordance with a request from the corresponding subscriber.
摘要:
A compound of the formula: ##STR1## wherein R.sup.1 is aryl, or a group of the formula: ##STR2## wherein X is CH or N, and Z is O or N--R.sup.5,in which R.sup.5 is hydrogen or lower alkyl,R.sup.2 is hydroxy or lower alkoxy,R.sup.3 is hydrogen or lower alkyl which may have suitable substituent(s),R.sup.4 is ar(lower)alkyl which may have suitable substituent(s),A is carbonyl or sulfonyl, andY is a bond or lower alkenylene,and pharmaceutically acceptable salt thereof. The disclosed compounds are useful for treating respiratory diseases such as bronchaedema.
摘要翻译:下式的化合物:其中R 1是芳基或下式的基团:其中X是CH或N,Z是O或N-R 5,其中R 5是氢或低级烷基,R 2 R 3为氢或可具有合适取代基的低级烷基,R 4为可具有合适取代基的芳(低级)烷基,A为羰基或磺酰基,Y为键或低级 亚烯基及其药学上可接受的盐。 所公开的化合物可用于治疗呼吸系统疾病如支气管哮喘。
摘要:
Peptide compounds having Substance P antagonism of the formula: ##STR1## wherein R.sup.1 is lower alkyl, aryl, arylamino, pyridyl, pyrrolyl, pyrazolopyridyl, quinolyl, or a group of the formula: ##STR2## wherein the symbol of a line and dotted line is a single bond or a double bond; X is CH or N; Z is O, S or NH; R.sup.2 is hydrogen or lower alkyl; R.sup.3 is hydrogen or hydroxy; R.sup.4 is lower alkyl which may have suitable substituent(s); R.sup.5 is ar(lower)alkyl which may have suitable substituent(s) or pyridyl(lower)alkyl, or R.sup.4 and R.sup.5 are linked together to form benzene-condensed lower alkylene; A is an amino acid residue excepting D-Trp, which may have suitable substituent(s); and Y is bond, lower alkylene or lower alkenylene;and their pharmaceutically acceptable salts are disclosed.
摘要:
An inspecting method and device for inspecting an object or objects such as photomasks having a plurality of identical patterns, to detect defects of the patterns, wherein the object is placed such that the patterns lie in the same plane, and an inspection mask having a plurality of translucent apertures is placed such that the inspection mask is adjacent and parallel to the object. The inspection mask and the object are moved relative to each other whereby each aperture is positioned opposite to mutually corresponding portions of the patterns. The object and inspection mask are irradiated with rays of light emitted in a direction substantially normal to the plane of relative movements thereof. The rays of light transmitted through the apertures and the object are converted into electric signals, and the electric signals associated with the corresponding portions of the patterns are compared with each other, prior to obtaining the electric signals of all of the plurality of patterns. If the electric signals of the corresponding portions of the patterns differ from each other, these portions are determined to be defective.
摘要:
A fuel injection nozzle is disclosed, which comprises a nozzle body provided with an injection hole. A nozzle needle is slidably fitted into the nozzle body, to open or close the injection hole of the nozzle body. The nozzle needle is provided with a needle pin which is insertable into the injection hole. The needle pin involves a taper section which is progressively slenderized toward the combustion chamber of an internal combustion engine. A plurality of axially extending flattened surface portions are formed on the outer peripheral wall of the taper section of the needle pin. As a result, the annular gap region defined between the outer peripheral wall of the needle pin and the inner peripheral wall of the injection hole entails wider and narrower gap sections.
摘要:
Provided are a method of generating a low-capacity model capable of identifying an object with high accuracy, and creating an image database using the model, a processing program for executing the method, and a processing apparatus that executes the process. The method for compiling an image database that is used for a three-dimensional object recognition includes a steps of extracting vectors as local descriptors from a plurality of images each image showing a three-dimensional object as seen from different viewpoints, a model creating step of evaluating the degree of contribution of each local descriptor to identification of the three-dimensional object, and creating a three-dimensional object model systematized to ensure approximate nearest neighbor search using the individual vectors which satisfy criteria, and a registration step of adding an object identifier to the created object model and registering the object model into an image database. In the model creating step, the local descriptor to be used in the model is selected based on the contributions of the individual vectors which are evaluated in such a way that when a vector extracted from one image of one three-dimensional object is an approximate nearest neighbor to another vector relating to an image of the three-dimensional object seen from a different viewpoint, the vector has a positive contribution, whereas when the vector is an approximate nearest neighbor to another vector relating to a different three-dimensional object, the vector has a negative contribution. The processing program is designed to execute the method, and the processing apparatus executes the process.