公开(公告)号：US20100093825A1

公开(公告)日：2010-04-15

申请号：US12654018

申请日：2009-12-08

申请人： Yasumichi Fukuda ,  Yoshikazu Asahina ,  Kohei Ohata ,  Kazuya Yokota ,  Koji Murakami ,  Toshiyuki Matsui

发明人： Yasumichi Fukuda ,  Yoshikazu Asahina ,  Kohei Ohata ,  Kazuya Yokota ,  Koji Murakami ,  Toshiyuki Matsui

IPC分类号： A61K31/40 ,  A61K31/4025 ,  A61P3/00 ,  A61P19/10 ,  A61P35/00

CPC分类号： C07D405/12 ,  C07D207/16 ,  Y02P20/55

摘要： SummaryNovel bicycloester derivatives and pharmaceutically acceptable salts thereof have high DPP-IV inhibitory activity.Solving MeansThe novel bicycloester derivatives are represented by the general formula (1): Pharmaceutically acceptable salts thereof are also included (Example: (2S,4S)-1-[[(N-(4-ethoxycarbonylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile)).

摘要翻译： 发明概述新型双环衍生物及其药学上可接受的盐具有高的DPP-IV抑制活性。 解决方法新型双环衍生物由通式（1）表示：其药学上可接受的盐也包括在实施例中：（2S，4S）-1 - [[（N-（4-乙氧羰基双环[2.2.2] 吡啶-1-基）氨基]乙酰基] -4-氟吡咯烷-2-腈））。

公开(公告)号：US20090124631A1

公开(公告)日：2009-05-14

申请号：US12209419

申请日：2008-09-12

申请人： Zuomei Li ,  Koji Murakami

发明人： Zuomei Li ,  Koji Murakami

IPC分类号： A61K31/506 ,  A61P35/00 ,  A61K31/4439 ,  A61K31/337 ,  A61K31/40 ,  A61K31/4468 ,  A61K31/496 ,  A61K31/427

CPC分类号： A61K45/06 ,  A61K31/337 ,  A61K31/402 ,  A61K31/4439 ,  A61K31/451 ,  A61K31/496 ,  A61K31/506 ,  A61K2300/00

摘要： The invention relates to the treatment of mammalian diseases manifested by abnormal cell growth and/or abnormal cell proliferation. More particularly, the invention relates to the use of combination therapies to control abnormal cell growth and/or abnormal cell proliferation. In particular, the invention relates to the use of isotype-selective inhibitors of histone deacetylases 1, 2 and/or 3 (HDACs 1-3), as well as isotype-selective inhibitors of HDAC1 and/or HDAC2, to potentiate therapeutic activity of microtubule-stabilization agents.

摘要翻译： 本发明涉及由异常细胞生长和/或异常细胞增殖所表现的哺乳动物疾病的治疗。 更具体地，本发明涉及组合疗法用于控制异常细胞生长和/或异常细胞增殖的用途。 特别地，本发明涉及组蛋白脱乙酰酶1,2和/或3（HDAC1-3）的同种型选择性抑制剂以及HDAC1和/或HDAC2的同种型选择性抑制剂在增强治疗活性中的用途 微管稳定剂。

公开(公告)号：US20080303338A1

公开(公告)日：2008-12-11

申请号：US12155246

申请日：2008-05-30

申请人： Kazuo Takeda ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kenji Fukuda ,  Kazuki Yamazaki

发明人： Kazuo Takeda ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kenji Fukuda ,  Kazuki Yamazaki

IPC分类号： B60B1/00

CPC分类号： B60B7/14

摘要： A wheel for vehicle includes a wheel body, a decorated member, and a visible space. The wheel body has a rim, a hub, and a plurality of spokes connecting the hub and the rim. The decorated member is made from resin, is disposed on a surface of at least one of the spokes, and is retained to the wheel body. The visible space is disposed between the decorated member and the one of the spokes at least, exhibits a height in an axial direction of the wheel body, and is visible from an axial outer side of the wheel body.

摘要翻译： 用于车辆的车轮包括轮体，装饰构件和可见空间。 轮体具有轮辋，轮毂和连接轮毂和轮辋的多个辐条。 装饰构件由树脂制成，设置在至少一个辐条的表面上，并被保持在轮体上。 所述可视空间至少设置在所述装饰构件和所述一个所述辐条之间，在所述车轮主体的轴向方向上具有高度，并且从所述车轮主体的轴向外侧可见。

公开(公告)号：US20050217798A1

公开(公告)日：2005-10-06

申请号：US11088211

申请日：2005-03-22

申请人： Akira Sugiyama ,  Shuhichi Kitamura ,  Koji Murakami ,  Daisuke Takahashi ,  Shohzoh Yoshimoto

发明人： Akira Sugiyama ,  Shuhichi Kitamura ,  Koji Murakami ,  Daisuke Takahashi ,  Shohzoh Yoshimoto

IPC分类号： H05H1/24 ,  C23C16/50 ,  C23F1/00 ,  H01J37/32 ,  H01L21/304 ,  H01L21/3065

CPC分类号： H01J37/32009 ,  H01J37/32082 ,  H01J37/32532

摘要： The plasma processing apparatus includes main electrodes 5, 31 opposed to each other with a plasma processing space 15 interposed therebetween. The plasma processing apparatus further has a side electrode 6 opposed to side faces 5B-1, 5B-2 of the main electrode 5, as well as a side electrode 32 opposed to side faces 31B-1, 31B-2 of the main electrode 31. Therefore, in addition to the plasma processing space 15 between the main electrode 5 and the main electrode 31, an electric field can be formed in spaces between the side faces of the main electrodes 5, 31 and the side electrodes 6, 32, the spaces serving as predischarge areas 16-1, 16-2. By this electric field, processing gas present in the predischarge areas 16-1, 16-2 can be transformed into plasma. Electrons and excitation species of the plasma generated in these predischarge areas 16-1, 16-2 can be supplied directly to the plasma processing space 15.

摘要翻译： 等离子体处理装置包括彼此相对的主电极5,31，其间插入等离子体处理空间15。 等离子体处理装置还具有与主电极5的侧面5B-B-B-B-B相对的侧面电极6以及与侧面31B-1，31B-2相对的侧面电极32 主电极31.因此，除了主电极5和主电极31之间的等离子体处理空间15之外，可以在主电极5,31的侧面与侧电极6之间的空间中形成电场 ，32，用作预充电区域16-1,16-2的空间。通过该电场，存在于预充电区域16-1,16-2中的处理气体可以转换成等离子体。 在这些预放电区域16-1,16-2中产生的等离子体的电子和激发物质可以直接供应到等离子体处理空间15。

公开(公告)号：US06730687B1

公开(公告)日：2004-05-04

申请号：US10049645

申请日：2002-02-25

申请人： Hiroyuki Miyachi ,  Masahiro Nomura ,  Takahiro Tanase ,  Koji Murakami ,  Masaki Tsunoda

发明人： Hiroyuki Miyachi ,  Masahiro Nomura ,  Takahiro Tanase ,  Koji Murakami ,  Masaki Tsunoda

IPC分类号： A61K31426

CPC分类号： C07D277/34

摘要： The invention provides novel substituted benzylthiazolidine-2,4-dione derivatives that bind to receptor to activate as ligands of human peroxisome proliferator-activated receptor (PPAR) and exhibit blood glucose-decreasing action and lipid-decreasing action, and processes for preparing them. It relates to substituted benzylthiazolidine-2,4-dione derivatives represented by the general formula (1) [wherein the bond mode of A denotes —CH2CONH—, —NHCONH—, —CH2CH2CO— or —NHCOCH2—, and B denotes a lower alkyl group with carbon atoms of 1 to 4, lower alkoxy group with carbon atoms of 1 to 3, halogen atom, trifluoromethyl group, trifluoromethoxy group, phenyl group which is unsubstituted or may have substituents, phenoxy group which is unsubstituted or may have substituents or benzyloxy group which is unsubstituted or may have substituents], their medicinally acceptable salts, their hydrates and processes for preparing them.

摘要翻译： 本发明提供了新的取代的苄基噻唑烷-2,4-二酮衍生物，其结合受体以作为人类过氧化物酶体增殖物激活受体（PPAR）的配体活化并显示出血糖降低作用和降脂作用，以及制备它们的方法。 它涉及由通式（1）表示的取代的苄基噻唑烷-2,4-二酮衍生物[其中A的键合模式表示-CH 2 CONH-，-NHCONH-，-CH 2 CH 2 CO-或-NHCOCH 2 - ，B表示低级烷基 具有1至4个碳原子的烷基，具有1至3个碳原子的低级烷氧基，卤素原子，三氟甲基，三氟甲氧基，未取代或可具有取代基的苯基，未被取代或可具有取代基的苯氧基或可具有取代基的苯氧基 未取代或可具有取代基的基团]，它们的药学上可接受的盐，它们的水合物及其制备方法。

公开(公告)号：US5902138A

公开(公告)日：1999-05-11

申请号：US599953

申请日：1996-02-14

申请人： Koji Murakami

发明人： Koji Murakami

IPC分类号： H01R9/24 ,  H01R31/08 ,  H02G3/16 ,  H05K1/00 ,  H05K1/02 ,  H05K3/00 ,  H05K3/20 ,  H05K3/30 ,  H05K3/40 ,  H01R9/09

CPC分类号： H05K3/306 ,  H01R9/2466 ,  H05K1/0263 ,  H01R12/59 ,  H01R31/08 ,  H05K1/0284 ,  H05K1/0393 ,  H05K2201/0352 ,  H05K2201/09045 ,  H05K2201/091 ,  H05K2201/09118 ,  H05K2201/10272 ,  H05K2201/10583 ,  H05K2201/10651 ,  H05K2203/167 ,  H05K3/0058 ,  H05K3/202 ,  H05K3/4084

摘要： A branch junction box containing a flexible printed circuit sheet includes circuit terminals and other parts which are easily mounted. A first insulation plate is provided on one of its faces, with a plurality of printed circuit terminals vertically fixed therethrough. On its other face, the first insulation plate carries a flexible printed circuit sheet, the printed circuit of which is electrically connected to the circuit terminals. The surface of the insulating plate facing the circuit terminals may be provided with bus bar wiring patterns and corresponding bus bar terminals. These circuit terminals and bus bar terminals are branch-connected to wiring harnesses in a proper and reliable way through connectors formed in the casing of the box.

摘要翻译： 包含柔性印刷电路板的分支接线盒包括电路端子和容易安装的其它部件。 第一绝缘板设置在其一个面上，多个印刷电路端子垂直固定在其中。 在另一面上，第一绝缘板带有柔性印刷电路板，其印刷电路电连接到电路端子。 面向电路端子的绝缘板的表面可以设置有母线布线图案和相应的母线端子。 这些电路端子和母线端子通过形成在盒的壳体中的连接器以适当且可靠的方式分支连接到线束。

公开(公告)号：US5750515A

公开(公告)日：1998-05-12

申请号：US737799

申请日：1996-11-26

申请人： Jiro Shibata ,  Konstanty Wierzba ,  Koji Murakami ,  Yuji Yamada ,  Koichi Shudo

发明人： Jiro Shibata ,  Konstanty Wierzba ,  Koji Murakami ,  Yuji Yamada ,  Koichi Shudo

IPC分类号： A61K31/192 ,  A61K31/196 ,  A61K31/695 ,  A61P35/04 ,  A61K31/19 ,  A61K31/20

CPC分类号： A61K31/695 ,  A61K31/192 ,  A61K31/196

摘要： The present invention relates to a cancer metastasis inhibitor comprising a benzoic acid derivative as an active ingredient represented by the formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and each represents hydrogen atom, hydroxyl group or trimethylsilyl group, or R.sub.3 and R.sub.4 are bonded to each other to form a tetramethylene group substituted with lower alkyl group, and X represents group --COCH.dbd.C(OH)--, group --NHCO-- or group --CONH--, provided that when R.sub.3 and R.sub.4 are bonded to each other to form a tetramethylene group substituted with lower alkyl group, X is group --COCH.dbd.C(OH)-- or group --CONH--, use of the benzoic acid derivative for preparing the cancer metastasis inhibitor and method of inhibiting cancer metastasis, characterized in that an effective amount of the benzoic acid derivative is administered to a mammalian animal for inhibiting metastasis of cancer. The benzoic acid derivative represented by the above formula (I) has extremely good metastasis inhibiting properties.

摘要翻译： PCT No.PCT / JP96 / 00980 Sec。 371日期1996年11月26日 102（e）1996年11月26日PCT PCT 1996年4月10日PCT公布。 第WO96 / 32101号公报 日期：1996年10月17日本发明涉及包含苯甲酸衍生物作为由式（I）表示的活性成分的癌症转移抑制剂，其中R1，R2，R3和R4相同或不同， 各自表示氢原子，羟基或三甲基甲硅烷基，或者R 3和R 4相互键合形成被低级烷基取代的四亚甲基，X表示-COCH = C（OH） - 基团，-NHCO-或基团 -CONH-，条件是当R 3和R 4彼此键合以形成被低级烷基取代的四亚甲基时，X是基团-COCH = C（OH） - 或基团-CONH-，使用苯甲酸衍生物 制备癌转移抑制剂和抑制癌转移的方法，其特征在于向哺乳动物施用有效量的苯甲酸衍生物以抑制癌转移。 上述式（I）表示的苯甲酸衍生物具有极好的转移抑制性质。

公开(公告)号：US5551912A

公开(公告)日：1996-09-03

申请号：US297509

申请日：1994-08-29

申请人： Takatoshi Takemoto ,  Tosikazu Chida ,  Noriaki Kano ,  Eizi Ito ,  Koji Murakami ,  Takasi Itagaki ,  Kozo Sekimoto ,  Masanori Suzuki

发明人： Takatoshi Takemoto ,  Tosikazu Chida ,  Noriaki Kano ,  Eizi Ito ,  Koji Murakami ,  Takasi Itagaki ,  Kozo Sekimoto ,  Masanori Suzuki

IPC分类号： B65G47/66 ,  G07D9/00 ,  G07D1/00 ,  B65G47/56

CPC分类号： G07D9/00 ,  B65G47/66 ,  Y10S193/01

摘要： The ending side of one coin conveying endless belt is made higher than the starting side of another adjacent coin conveying endless belt. Between the ending side of the one coin conveying belt and the starting side of the another coin conveying belt, there is provided a coin slide to let the coins, which have reached the ending side of the one coin conveying belt, slide down to the starting side of the another coin conveying belt. By using the coin slide, the transference of coins from the one coin conveying belt to the another coin conveying belt can be ensured.

摘要翻译： 输送环形带的一个硬币的终端被制成高于另一个相邻硬币输送环形带的起始侧。 在一个硬币输送带的结束侧和另一个硬币输送带的起始侧之间，设置有硬币滑块，以使已经到达一个硬币输送带的终止侧的硬币向下滑动到起始 另一个硬币传送带的一侧。 通过使用硬币滑块，可以确保硬币从一个硬币输送带转移到另一个硬币输送带。

公开(公告)号：US4641067A

公开(公告)日：1987-02-03

申请号：US774843

申请日：1985-09-11

申请人： Ryuji Iizawa ,  Koji Murakami

发明人： Ryuji Iizawa ,  Koji Murakami

IPC分类号： H02H3/00 ,  H02H7/085 ,  H02P7/00 ,  H02P1/22

CPC分类号： H02H7/0851 ,  H02P7/03 ,  H02H3/006

摘要： The present invention discloses a technique to avoid catching a foreign object in a power window by detecting overload of the window drive motor and stopping or reversing the rotation of the motor in response to said detection. The reference value for detecting overload is updated in accordance with a actual load of the motor in each predetermined time interval .DELTA.T but, in the present invention, when the start of an increase of overload is detected, the beginning of time period .DELTA.T is started again from that time, and thereby detection of overload is always carried out within the shortest period. Moreover, a variety of check mechanisms are also provided for ensuring the fail-safe function of the apparatus and for enhancing reliability of the protective apparatus.

摘要翻译： 本发明公开了一种通过检测窗驱动马达的过载并响应于所述检测停止或反转马达的旋转而避免在电动窗中卡住异物的技术。 根据每个预定时间间隔DELTA T中的电动机的实际负载来更新检测过载的参考值，但是在本发明中，当检测到过载增加的开始时，时间段DELTA T的开始是 从那时开始重新开始，从而在最短的时间内始终进行过载检测。 此外，还提供了各种检查机构，用于确保设备的故障安全功能并提高保护装置的可靠性。

公开(公告)号：US09325745B2

公开(公告)日：2016-04-26

申请号：US13123133

申请日：2009-10-16

申请人： Masashi Toyama ,  Koji Murakami ,  Yoshiko Sueda

发明人： Masashi Toyama ,  Koji Murakami ,  Yoshiko Sueda

IPC分类号： G06F15/16 ,  H04L29/06 ,  G06Q30/06 ,  H04L29/08

CPC分类号： H04L65/1069 ,  G06Q30/06 ,  H04L65/1006 ,  H04L65/4023 ,  H04L67/02 ,  H04L67/22

摘要： A service providing server collects call session information that identifies communication established between terminals and service usage IDs that identify the terminals for each terminal. Then, the service providing server identifies call session information pieces indicating the same communication and associates Web services with each other. When the service providing server provides the associated Web services to the terminals, the service providing server identifies service usage IDs that identify the terminals and control provision of the Web services so that each Web service is provided according to history information stored in a history information database in association with service usage IDs.

摘要翻译： 服务提供服务器收集标识终端之间建立的通信和识别每个终端的终端的服务使用ID的呼叫会话信息。 然后，服务提供服务器识别表示相同通信的呼叫会话信息，并将Web服务相互关联。 当服务提供服务器向终端提供关联的Web服务时，服务提供服务器识别标识终端的服务使用ID并控制Web服务的提供，使得根据历史信息数据库中存储的历史信息提供每个Web服务 与服务使用ID相关联。