DERIVATE, PREPARATION METHOD AND USE OF 10-METHOXYCAMPTOTHECINE
    41.
    发明申请
    DERIVATE, PREPARATION METHOD AND USE OF 10-METHOXYCAMPTOTHECINE 有权
    衍生物,制备方法和使用10-甲氧基角蛋白

    公开(公告)号:US20140194458A1

    公开(公告)日:2014-07-10

    申请号:US14124570

    申请日:2012-06-15

    IPC分类号: C07D491/22

    CPC分类号: C07D491/22

    摘要: Provided is a 10-methoxycamptothecine derivate of formula (1), wherein R is selected from hydrogen, C1-6 alkyl, C1-6 haloalkyl, aryl substituted C1-6 alkyl, phosphate substituted C1-6 alkyl, amino-substituted C1-6 alkyl, carboxyl substituted C1-6 alkyl, hydroxyl substituted C1-6 alkyl, and amide- substituted C1-6 alkyl; R1 is selected from hydrogen and t-butoxycarbonyl substituted amino. Also provided in the present invention are the preparation method of the derivate and the use thereof in anti-tumor drug preparation.

    摘要翻译: 提供式(1)的10-甲氧基喜树碱衍生物,其中R选自氢,C 1-6烷基,C 1-6卤代烷基,芳基取代的C 1-6烷基,磷酸酯取代的C 1-6烷基,氨基取代的C 1-6 烷基,羧基取代的C 1-6烷基,羟基取代的C 1-6烷基和酰胺取代的C 1-6烷基; R1选自氢和叔丁氧基羰基取代的氨基。 本发明还提供了其在抗肿瘤药物制备中的衍生及其用途的制备方法。

    Cardiac flow quantification with volumetric imaging data
    43.
    发明授权
    Cardiac flow quantification with volumetric imaging data 有权
    心脏流量定量与体积成像数据

    公开(公告)号:US08696579B2

    公开(公告)日:2014-04-15

    申请号:US13151803

    申请日:2011-06-02

    IPC分类号: A61B8/00

    摘要: A method quantifies cardiac volume flow for an imaging sequence. The method includes receiving data representing three-dimensions and color Doppler flow data over a plurality of frames, constructing a ventricular model based on the data representing three-dimensions for the plurality of frames, the ventricular model including a sampling plane configured to measure the cardiac volume flow, computing volume flow samples based on the sampling plane and the color Doppler flow data, and correcting the volume flow samples for aliasing based on volumetric change in the ventricular model between successive frames of the plurality of frames.

    摘要翻译: 一种方法量化成像序列的心脏体积流量。 该方法包括在多个帧上接收表示三维和彩色多普勒流数据的数据,基于代表多个帧的三维的数据构建心室模型,心室模型包括被配置成测量心脏的采样平面 体积流量,基于采样平面和彩色多普勒流数据的计算体积流量样本,以及基于多个帧的连续帧之间的心室模型的体积变化来校正用于混叠的体积流量样本。

    Soybean event pDAB9582.814.19.1 detection method
    44.
    发明授权
    Soybean event pDAB9582.814.19.1 detection method 有权
    大豆事件pDAB9582.814.19.1检测方法

    公开(公告)号:US08632978B2

    公开(公告)日:2014-01-21

    申请号:US13558982

    申请日:2012-07-26

    IPC分类号: C12Q1/68 C07H21/04 C12P19/34

    CPC分类号: C12Q1/6895 C12Q2600/16

    摘要: Soybean Event pDAB9582.814.19.1 comprises genes encoding Cry1F, Cry1Ac (synpro), and PAT, affording insect resistance and herbicide tolerance to soybean crops containing the event, and enabling methods for crop protection and protection of stored products. The invention provides PCR event detection methods.

    摘要翻译: 大豆事件pDAB9582.814.19.1包含编码Cry1F,Cry1Ac(synpro)和PAT的基因,为含有该事件的大豆作物提供抗昆虫抗性和除草剂耐受性,以及对作物保护和保护储存产品的有效方法。 本发明提供PCR事件检测方法。

    Power converter with extremely low standby power consumption
    47.
    发明授权
    Power converter with extremely low standby power consumption 有权
    电源转换器具有极低的待机功耗

    公开(公告)号:US08199543B2

    公开(公告)日:2012-06-12

    申请号:US12502801

    申请日:2009-07-14

    IPC分类号: H02M7/00

    CPC分类号: H02M7/1623

    摘要: The present invention relates to a power converter with extremely low standby power consumption. The power converter comprises a rectification module having at least one unilateral switch which has a control terminal, an anode terminal and a cathode terminal. The control terminal is coupled to a control signal, wherein when the control signal issues a first level, the channel between the anode terminal and the cathode terminal is enabled to act as a unilateral switch; and when the control signal issues a second level, the channel between the anode terminal and the cathode terminal is open circuited.

    摘要翻译: 本发明涉及具有极低待机功耗的功率转换器。 功率转换器包括具有至少一个具有控制端子,阳极端子和阴极端子的单向开关的整流模块。 控制端子耦合到控制信号,其中当控制信号发出第一电平时,阳极端子和阴极端子之间的通道能够用作单向开关; 并且当控制信号发出第二电平时,阳极端子和阴极端子之间的通道开路。

    Distributed cache system
    48.
    发明授权
    Distributed cache system 有权
    分布式缓存系统

    公开(公告)号:US08175233B2

    公开(公告)日:2012-05-08

    申请号:US11053411

    申请日:2005-02-07

    IPC分类号: H04M1/64

    摘要: An integrated messaging system for performing various types of messaging across different types of networks, including integrated user interfaces and administrator interfaces. Embodiments include a communication server that couples among networks of different types, and an interface module that couples to the communication server. The interface module may be hosted on a messaging server of a network. The interface module pulls various user information from the messaging server, including information relevant to at least the network that includes the messaging server. A cache couples to the communication server and to the interface module to hold information from the communication server and/or the user information pulled from messaging server. The interface module directs a message from the messaging server and/or the cache to at least one device on the networks using the user information.

    摘要翻译: 一种用于在不同类型网络中执行各种类型的消息传递的集成消息系统,包括集成的用户界面和管理员界面。 实施例包括在不同类型的网络之间耦合的通信服务器和耦合到通信服务器的接口模块。 接口模块可以被托管在网络的消息传递服务器上。 接口模块从消息收发服务器提取各种用户信息,包括至少与包括消息收发服务器的网络相关的信息。 高速缓存耦合到通信服务器和接口模块以保存来自通信服务器的信息和/或从消息服务器提取的用户信息。 接口模块使用用户信息将消息从消息服务器和/或缓存引导到网络上的至少一个设备。

    ELECTRIC VEHICLE ROLLOVER DETECTION SYSTEM AND METHOD
    49.
    发明申请
    ELECTRIC VEHICLE ROLLOVER DETECTION SYSTEM AND METHOD 审中-公开
    电动车轮检测系统及方法

    公开(公告)号:US20120016544A1

    公开(公告)日:2012-01-19

    申请号:US12938047

    申请日:2010-11-02

    摘要: An apparatus for detecting change in orientation comprises a first position sensor and a second position sensor. The position sensors are in different orientations. The outputs of the position sensors are filtered to smooth out instantaneous and/or insignificant changes in orientation, or noise. A processor or logic circuitry is configured to determine a change in both outputs, and communicate such a change. Furthermore, the processor or logic circuitry is configured to electrically and/or physically de-couple batteries from a power delivery system in an EV.

    摘要翻译: 用于检测取向变化的装置包括第一位置传感器和第二位置传感器。 位置传感器处于不同的方向。 过滤位置传感器的输出以平滑方向或噪声的瞬时和/或微不足道的变化。 处理器或逻辑电路被配置为确定两个输出的变化,并且传达这样的改变。 此外,处理器或逻辑电路被配置为电动和/或物理地将电池从EV中的电力输送系统中去耦。

    BATTERY PACK ENUMERATION METHOD
    50.
    发明申请
    BATTERY PACK ENUMERATION METHOD 有权
    电池包计算方法

    公开(公告)号:US20120013290A1

    公开(公告)日:2012-01-19

    申请号:US12938277

    申请日:2010-11-02

    IPC分类号: H02J7/00

    摘要: A method of registering a plurality of Battery-Monitoring-Units (BMUs) in a battery pack with a Battery-Management-System (BMS), the method comprising: providing an indication to a user, wherein the indication prompts the user to register one of the BMUs with the BMS; the user performing an action on a communication-initiating mechanism on one of the BMUs, wherein the communication-initiating mechanism is configured to initiate the sending of a communication by the BMU to the BMS in response to the user performing the action; the BMU sending a communication to the BMS in response to the user performing the action on the communication-initiating mechanism; the BMS receiving the communication from the BMU; and the BMS registering the BMU in response to receiving the communication from the BMU.

    摘要翻译: 一种在具有电池管理系统(BMS)的电池组中登记多个电池监视单元(BMU)的方法,所述方法包括:向用户提供指示,其中所述指示提示用户注册一个 的BMU与BMS; 所述用户对所述BMU之一对通信发起机制执行动作,其中所述通信发起机制被配置为响应于所述用户执行所述动作而启动所述BMU向所述BMS发送通信; 响应于用户对通信发起机制执行动作,BMU向BMS发送通信; BMS从BMU接收通信; 并且BMS响应于接收到BMU的通信而注册BMU。