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    Spectrometer attachments and phosphorescence decay measurement
    41.
    发明申请
    Spectrometer attachments and phosphorescence decay measurement 失效
    光谱仪附件和磷光衰减测量

    公开(公告)号：US20040036871A1

    公开(公告)日：2004-02-26

    申请号：US10621648

    申请日：2003-07-17

    Inventor： Vanessa Mary Joy McCallum ,  Martin Kaselis ,  Hans Heinrich Egli

    IPC: G01J003/28

    CPC classification number: G01J3/4406 ,  G01J3/0275 ,  G01J3/0291 ,  G01J3/28

    Abstract: A spectrometry instrument with exchangeable accessories (34, 48, 50, 52) providing, for example, different sample presentation facilities. The accessories include a manually operable cam-lock facility (54, 68) for quick and easy attachment of an accessory to the instrument. The instrument also includes an electrical circuit (86-90), which is completed by a circuit portion (100) in an accessory when the accessory is attached to the instrument, for generating a unique identifying voltage (94) to thereby identify that accessory. This allows for automatic loading in a controlling computer of programs for setting up and running the instrument for measurement regimes using that accessory. The spectrometry instrument is preferably a spectrophotometer used for phosphorescence decay measurements in which sequential phosphorescence emission measurements data from each of a number of excitation cycles applied to a sample are taken and then reassembled into a correct time sequence to define a phosphorescence decay characteristic for the sample, that is, measured data points from a second (and subsequent) excitation cycle are interleaved with those from a first excitation cycle. This significantly reduces the time for establishing a phosphorescence decay characteristic.

    Abstract translation: 一种具有可交换附件（34,48,50,52）的光谱仪器，其提供例如不同的样品呈现设备。 附件包括一个可手动操作的凸轮锁定设备（54,68），用于将附件快速方便地附接到仪器上。 仪器还包括一个电路（86-90），当附件附接到仪器上时，该电路由附件中的电路部分（100）完成，用于产生唯一的识别电压（94），从而识别该附件。 这允许在控制计算机中自动加载用于使用该附件设置和运行用于测量方案的仪器的程序。 光谱仪器优选是用于磷光衰变测量的分光光度计，其中采用从施加到样品的多个激发循环中的每一个的顺序磷光发射测量数据，然后重新组装成正确的时间序列，以定义样品的磷光衰减特性 也就是说，来自第二激励周期（和随后）的测量数据点与来自第一激励周期的测量数据点交错。 这显着地减少了建立磷光衰变特性的时间。

    Accurate instrumetation for optical measurement of samples
    43.
    发明申请
    Accurate instrumetation for optical measurement of samples 有权
    准确测量样品的光学测量

    公开(公告)号：US20030048447A1

    公开(公告)日：2003-03-13

    申请号：US09947571

    申请日：2001-09-07

    Inventor： Raimo Harju ,  Christer Isaksson

    IPC: G01N021/25

    CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/76 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484

    Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more accurate instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument where there is an interface (218, 223, 233a, 233b, 238) for a changeable optical module (240), and excitation and/or emission beam is guided through an aperture of the optical module. This allows performing various types of measurements by changing an optical module without a problem lenses becoming unclean due to manual handling of the optical modules. The invention also makes possible to achieve an accurate measurement location and area within a sample.

    Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用于例如设备的改进和更精确的设备的功能。 荧光计，光度计和光度计。 本发明的目的是通过提供一种光学测量仪器实现的，其中存在用于可变光学模块（240）的界面（218,223,233a，233b，238），并且激发和/或发射光束被引导通过孔 的光模块。 这允许通过改变光学模块来执行各种类型的测量，而不会由于光学模块的手动处理而导致不透明的问题。 本发明还可以实现样品内的精确测量位置和面积。

    Coupling device for integrating and interfacing accessory modules with spectrometers for spectroscopic analysis
    44.
    发明授权
    Coupling device for integrating and interfacing accessory modules with spectrometers for spectroscopic analysis 失效
    用于将附件模块与光谱仪集成和连接的耦合装置进行光谱分析

    公开(公告)号：US6038022A

    公开(公告)日：2000-03-14

    申请号：US059959

    申请日：1998-04-14

    Applicant: George D. Jones ,  William B. DeSousa

    Inventor： George D. Jones ,  William B. DeSousa

    IPC: B01L9/00 ,  G01J3/02 ,  G01J3/28 ,  G01N21/01

    CPC classification number: G01J3/02 ,  B01L9/00 ,  G01J3/0275 ,  G01J3/0289 ,  G01J3/0291

    Abstract: A coupling mechanism for mounting a sample accessory assembly into a spectrometer. The accessory assembly, on which is mountable a sample to be analyzed by a spectrometer, has connecter ends which are insertable into stirrups on the sample compartment of the spectrometer. The connector ends and the stirrups have elements that ensure that the accessory assembly is properly aligned in the sample compartment of the spectrometer. The accessory assembly also has an electronic component, such as a circuit or programmable microchip, that is connected to the spectrometer when the accessory is mounted in the spectrometer. The electronic component provides information to the spectrometer identifying the accessory assembly being used so that a diagnostic test of the spectrometer can be performed to ascertain, for example, proper mounting of the accessory assembly in the spectrometer.

    Abstract translation: 用于将样品附件组件安装到光谱仪中的耦合机构。 附件组件可安装在由光谱仪分析的样品上，具有可插入光谱仪样品室上的马镫的连接端。 连接器端部并且箍筋具有确保附件组件在光谱仪样品室中正确对准的元件。 附件组件还具有电子部件，例如电路或可编程微芯片，当附件安装在光谱仪中时，其连接到光谱仪。 电子部件向光谱仪提供信息，以识别正在使用的附件组件，以便可以执行光谱仪的诊断测试，以确定例如将附件组件正确安装在光谱仪中。

    PORTABLE BIOSENSOR FOR AIR SAMPLE
    47.
    发明公开
    PORTABLE BIOSENSOR FOR AIR SAMPLE 审中-公开

    公开(公告)号：US20230296439A1

    公开(公告)日：2023-09-21

    申请号：US18123488

    申请日：2023-03-20

    Applicant: The United States of America, as represented by the Secretary of the Navy

    Inventor： Kin Chiu Ng ,  Subrata Sanyal

    IPC: G01J3/44 ,  G06V40/13 ,  G01J3/02

    CPC classification number: G01J3/4412 ,  G06V40/1318 ,  G01J3/0286 ,  G01J3/0272 ,  G01J3/0229 ,  G01J3/0202 ,  G01J3/0227 ,  G01J3/0275

    Abstract: Provided is a portable biosensor that includes a sample filter cartridge, a filter collector, an optical sphere, an electromagnetic radiation emitter, a photo-detector, a processor, a signal display, a vacuum pump, and a power supply. The sample filter cartridge selectively removes small molecules to minimize spectral interference in the detection signal. The sample is concentrated onto the filter collector and subjected to illumination by the electromagnetic radiation emitter, producing Raman-scattering. The optical sphere collects and distributes the Raman-scattering shifts, which then pass through a spectral filter to produce spectral filtered scattering, which is then reflected by the concave holographic flat-field grating onto the photo-detector. The data is displayed graphically to provide the Raman-scattering shift data. The data is compared with a database for sample identification. The device is contained within a housing that is small enough to be easily transported for field use.

    ELECTROMAGNETIC RADIATION SPECTRUM DETECTION SYSTEM
    48.
    发明公开
    ELECTROMAGNETIC RADIATION SPECTRUM DETECTION SYSTEM 审中-公开

    公开(公告)号：US20230288256A1

    公开(公告)日：2023-09-14

    申请号：US18007447

    申请日：2021-07-29

    Applicant: Politecnico di Milano ,  UNIVERSITÀ DEGLI STUDI ROMA TRE

    Inventor： Jacopo Frigerio ,  Giovanni Isella ,  Andrea Ballabio ,  Andrea De Iacovo ,  Lorenzo Colace

    IPC: G01J3/28

    CPC classification number: G01J3/2823 ,  G01J3/2803 ,  G01J2003/2826 ,  G01J3/0275

    Abstract: An electromagnetic radiation spectrum detection system including a sensor device and an electronic control and processing module. The sensor device may include two photodiodes. The sensor device may convert an incident electromagnetic radiation (EMR) into electrical current. The electronic control and processing module may store numerical calibration values representative of a responsivity matrix of the sensor device. The electronic control and processing module may selectively provide the sensor device with electrical control voltage values (VB). The electronic control and processing module may process the values of detected electric currents (Iph) and the numerical calibration values to obtain spectrum information related to incident electromagnetic radiation spectrums. The electronic control and processing module may determine power spectral density of incident electromagnetic radiation.

    System and method for non-invasive measurement of analytes in vivo
    49.
    发明授权
    System and method for non-invasive measurement of analytes in vivo 有权

    公开(公告)号：US11740128B2

    公开(公告)日：2023-08-29

    申请号：US16927804

    申请日：2020-07-13

    Applicant: Sanguis Corporation

    Inventor： Jeffrey Owen Katz

    IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65 ,  G01J3/06 ,  G01N33/49

    CPC classification number: G01J3/4412 ,  G01J3/021 ,  G01J3/0202 ,  G01J3/0218 ,  G01J3/0275 ,  G01J3/06 ,  G01N21/65 ,  G01N33/492 ,  G01J2003/062 ,  G01J2003/064

    Abstract: A system for non-invasively interrogating an in vivo sample for measurement of analytes comprises a pulse sensor coupled to the in vivo sample for detect a blood pulse of the sample and for generating a corresponding pulse signal, a laser generator for generating a laser radiation having a wavelength, power and diameter, the laser radiation being directed toward the sample to elicit Raman signals, a laser controller adapted to activate the laser generator, a spectrometer situated to receive the Raman signals and to generate analyte spectral data; and a computing device coupled to the pulse sensor, laser controller and spectrometer which is adapted to correlate the spectral data with the pulse signal based on timing data received from the laser controller in order to isolate spectral components from analytes within the blood of the sample from spectral components from analytes arising from non-blood components of the sample.

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