公开(公告)号：US20130234313A1

公开(公告)日：2013-09-12

申请号：US13414902

申请日：2012-03-08

Applicant: James Cooper Wainerdi ,  Luigi Colombo ,  John Paul Tellkamp ,  Robert Reid Doering

Inventor： James Cooper Wainerdi ,  Luigi Colombo ,  John Paul Tellkamp ,  Robert Reid Doering

IPC: H01L23/34 ,  H01L23/48 ,  H01L21/78 ,  H01L21/56 ,  B82Y40/00 ,  B82Y99/00

CPC classification number: H01L23/373 ,  B82Y10/00 ,  C09J163/00 ,  H01L21/563 ,  H01L23/3107 ,  H01L23/49513 ,  H01L23/49541 ,  H01L23/49568 ,  H01L24/29 ,  H01L24/32 ,  H01L24/73 ,  H01L24/83 ,  H01L24/92 ,  H01L2224/29076 ,  H01L2224/291 ,  H01L2224/2919 ,  H01L2224/29193 ,  H01L2224/2929 ,  H01L2224/2939 ,  H01L2224/32245 ,  H01L2224/331 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/48472 ,  H01L2224/73265 ,  H01L2224/83104 ,  H01L2224/83139 ,  H01L2224/8314 ,  H01L2224/83141 ,  H01L2224/83191 ,  H01L2224/83192 ,  H01L2224/83193 ,  H01L2224/83862 ,  H01L2224/83897 ,  H01L2224/83951 ,  H01L2224/83986 ,  H01L2224/858 ,  H01L2224/85801 ,  H01L2224/8585 ,  H01L2224/85899 ,  H01L2224/9205 ,  H01L2924/10253 ,  H01L2924/12042 ,  H01L2924/15724 ,  H01L2924/181 ,  H01L2924/351 ,  H01L2924/00014 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2924/014

Abstract: An article of manufacture includes a semiconductor die (110) having an integrated circuit (105) on a first side of the die (110), a diffusion barrier (125) on a second side of the die (110) opposite the first side, a mat of carbon nanotubes (112) rooted to the diffusion barrier (125), a die attach adhesive (115) forming an integral mass with the mat (112) of the carbon nanotubes, and a die pad (120) adhering to the die attach adhesive and (115) and the mat (112) of carbon nanotubes for at least some thermal transfer between the die (110) and the die pad (120) via the carbon nanotubes (112). Other articles, integrated circuit devices, structures, and processes of manufacture, and assembly processes are also disclosed.

Abstract translation: 一种制造方法包括在管芯（110）的第一侧上具有集成电路（105）的半导体管芯（110），在与第一侧相对的管芯（110）的第二侧上的扩散阻挡层（125） 基于所述扩散阻挡层（125）的碳纳米管（112）垫，与所述碳纳米管的所述垫（112）形成整体的芯片附接粘合剂（115）和粘附到所述模具 附着粘合剂和（115）和碳纳米管的垫（112），以经由碳纳米管（112）在管芯（110）和管芯焊盘（120）之间进行至少一些热转移。 还公开了其它制品，集成电路器件，结构以及制造工艺和组装工艺。

公开(公告)号：US20130217658A1

公开(公告)日：2013-08-22

申请号：US13879652

申请日：2011-10-19

Applicant: Anthony William James Cooper ,  Paul Martin Gore ,  David House

Inventor： Anthony William James Cooper ,  Paul Martin Gore ,  David House

IPC: A61K31/415 ,  A61K45/06 ,  A61K31/4439 ,  C07D231/40 ,  C07D401/12

CPC classification number: A61K31/415 ,  A61K31/4439 ,  A61K45/06 ,  C07D231/40 ,  C07D401/12

Abstract: The present invention relates to pyrazole amide derivatives pharmaceutical compositions containing these compounds and to their use in therapy.

Abstract translation: 本发明涉及含有这些化合物的吡唑酰胺衍生物药物组合物及其在治疗中的用途。

公开(公告)号：US20130212269A1

公开(公告)日：2013-08-15

申请号：US13371633

申请日：2012-02-13

Applicant: Jussi KUOSA ,  Hannu VALTONEN ,  Hannu MAARANEN ,  Janne PÄNKÄLÄ ,  Kuan Eeik TAN ,  Jarkko KONOLA ,  Sami TIKKA ,  Jari SUKANEN ,  Pirkka PALOMÄKI ,  James COOPER

Inventor： Jussi KUOSA ,  Hannu VALTONEN ,  Hannu MAARANEN ,  Janne PÄNKÄLÄ ,  Kuan Eeik TAN ,  Jarkko KONOLA ,  Sami TIKKA ,  Jari SUKANEN ,  Pirkka PALOMÄKI ,  James COOPER

IPC: G06F15/173

CPC classification number: G06F21/6218 ,  G06F21/6272 ,  G06F2221/2103

Abstract: A method of data storage management. A server receives a data upload request from a remote client, the upload request including information identifying the data to be uploaded. The server determines that a duplicate of the data is stored at a data storage device. The server receives proof of possession information derived by the client from the data using additional information known to the server. On the basis of the received information, the server determines whether to allow the client or a user associated with the client to subsequently access the duplicate data stored at the data storage device.

Abstract translation: 一种数据存储管理方法。 服务器从远程客户端接收数据上传请求，上载请求包括识别要上传的数据的信息。 服务器确定数据副本存储在数据存储设备中。 服务器使用服务器已知的附加信息从数据中收到由客户端导出的占有信息的证明。 基于接收到的信息，服务器确定是否允许客户端或与客户端相关联的用户随后访问存储在数据存储设备中的重复数据。

公开(公告)号：US08207176B2

公开(公告)日：2012-06-26

申请号：US11908440

申请日：2006-03-24

Applicant: James F. Callahan ,  Jeffrey C. Boehm ,  Anthony William James Cooper ,  Stefano Livia ,  Paul Bamborough ,  Neysa Nevins ,  Zehong Wan ,  Beth A. Norton ,  Xichen Lin

Inventor： James F. Callahan ,  Jeffrey C. Boehm ,  Anthony William James Cooper ,  Stefano Livia ,  Paul Bamborough ,  Neysa Nevins ,  Zehong Wan ,  Beth A. Norton ,  Xichen Lin

IPC: C07D471/04 ,  A61K31/519 ,  A61P29/00 ,  C07D409/06

CPC classification number: C07D487/04

Abstract: The present invention is directed to novel substituted 2,4,8-trisubstituted 8H-pyrido[2,3-d]pyrimidin-7-one containing compounds, compositions, and use in therapy as CSBP/RK/p38 kinase inhibitors of Formulas (V) and (Va) wherein inter alia, G5 and G6 are nitrogen and CH, provided that only one of G5 or G6 is nitrogen and the other is CH; R1 is C(Z)N(R10′)(CR10R20)vRb, C(Z)O(CR10R20)vRb, N(R10′)C(Z)(CR10R20)vRb, N(R10′)C(Z)N(R10′)(CR10R20)vRb, or N(R10′)OC(Z)(CR10R20)vRb; R1′ is independently selected at each occurrence from halogen, C1-4 alkyl, halo-substituted-C1-4 alkyl, cyano, nitro, (CR10R20)v′NRdRd′, (CR10R20)v′C(O)R12, SR5, S(O)R5, S(O)2R5, or (CR10R20)v′OR13; Rb is hydrogen, C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-10 alkyl, aryl, arylC1-10alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic, or heterocyclylC1-10 alkyl moiety, which moieties, excluding hydrogen, may all be optionally substituted; X is R2, OR2′, S(O)mR2′, (CH2)n′N(R10′)S(O)mR2′, (CH2)n′N(R10′)C(O)R2′, (CH2)n′NR4R14, (CH2)n′N(R2′)(R2″), or N(R10′)RhNH—C(═N—CN)NRqRq′; and R3 is a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-10 alkyl, aryl, arylC1-10 alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic or a heterocyclylC1-10 alkyl moiety, and wherein each of these moieties may be optionally substituted.

Abstract translation: 本发明涉及新型取代的2,4,8-三取代8H-吡啶并[2,3-d]嘧啶-7-酮，其含有化合物，组合物和用于治疗作为CSBP / RK / p38激酶抑制剂的式 V）和（Va）其中G5和G6特别是氮和CH，条件是G5或G6中只有一个是氮，另一个是CH; R1是C（Z）N（R10'）（CR10R20）vRb，C（Z）O（CR10R20）vRb，N（R10'）C（Z）（CR10R20）vRb，N（R10'）C（Z） （R10'）（CR10R20）vRb或N（R10'）OC（Z）（CR10R20）vRb; 卤素，C 1-4烷基，卤素取代的C 1-4烷基，氰基，硝基，（CR 10 R 20）v'NR d R d'，（CR 10 R 20）v'C（O）R 12，SR 5， S（O）R 5，S（O）2 R 5或（CR 10 R 20）v'OR 13; R b是氢，C 1-10烷基，C 3-7环烷基，C 3-7环烷基C 1-10烷基，芳基，芳基C 1-10烷基，杂芳基，杂芳基C 1-10烷基，杂环基或杂环基C 1-10烷基部分， 可以任选地被取代; X是R2，OR2'，S（O）mR2'，（CH2）n'N（R10'）S（O）mR2'，（CH2）n'N（R10'）C（O）R2' ）n'NR4R14，（CH2）n'N（R2'）（R2“）或N（R10'）RhNH-C（= N-CN）NRqRq' 并且R 3是C 1-10烷基，C 3-7环烷基，C 3-7环烷基C 1-10烷基，芳基，芳基C 1-10烷基，杂芳基，杂芳基C 1-10烷基，杂环基或杂环基C 1-10烷基部分， 这些部分可以任选被取代。

公开(公告)号：US20120112500A1

公开(公告)日：2012-05-10

申请号：US12744197

申请日：2008-11-21

Applicant: Timothy Graham Rundle ,  Lauren Mary Grace Van Uden ,  Andrew Bissett ,  Gavin Edward Balasingam ,  Mitchell Hughes ,  Kerry Alan Reeves ,  Victoria Anne Bamford ,  Matthew James Cooper ,  Glen Wilson Porter ,  Stephen Lee Kim ,  Leslie Rae Witt ,  Stacey Hsu-Wen Chang ,  Jeremy John Sutherland ,  Daniel McLaughlin

Inventor： Timothy Graham Rundle ,  Lauren Mary Grace Van Uden ,  Andrew Bissett ,  Gavin Edward Balasingam ,  Mitchell Hughes ,  Kerry Alan Reeves ,  Victoria Anne Bamford ,  Matthew James Cooper ,  Glen Wilson Porter ,  Stephen Lee Kim ,  Leslie Rae Witt ,  Stacey Hsu-Wen Chang ,  Jeremy John Sutherland ,  Daniel McLaughlin

IPC: B60N2/01 ,  A47B83/02 ,  A47C7/72

CPC classification number: B64D11/00 ,  B64D11/06 ,  B64D11/0601 ,  B64D11/0638 ,  B64D11/0643

Abstract: The invention comprises a vehicle and seating arrangement having a central hub with four sides surrounded by four seats. The seats are arranged adjacent a respective side of the hub and facing substantially parallel to the side of the hub. In at least one embodiment, the arrangement provides access for each passenger to the aisle.

Abstract translation: 本发明包括车辆和座椅装置，其具有四个侧面被四个座椅包围的中心轮毂。 所述座位布置在所述轮毂的相应侧部附近并且基本上平行于所述轮毂的侧面。 在至少一个实施例中，该布置为每个乘客提供通向通道的通道。

公开(公告)号：US20110132811A1

公开(公告)日：2011-06-09

申请号：US12967637

申请日：2010-12-14

Applicant: James Cooper Wainerdi ,  Robert Reid Doering ,  Luigi Colombo

Inventor： James Cooper Wainerdi ,  Robert Reid Doering ,  Luigi Colombo

IPC: B03C1/00 ,  B03C1/005 ,  B03C1/02 ,  B03C1/025

CPC classification number: C01B31/0266 ,  B03C1/005 ,  B03C1/0335 ,  B03C1/035 ,  B03C2201/20 ,  B03C2201/22 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/172 ,  C01B2202/02 ,  C01B2202/22 ,  Y10S977/751 ,  Y10S977/845

Abstract: A process of sorting metallic single wall carbon nanotubes (SWNTs) from semiconducting types by disposing the SWNTs in a dilute fluid, exposing the SWNTs to a dipole-inducing magnetic field which induces magnetic dipoles in the SWNTs so that a strength of a dipole depends on a conductivity of the SWNT containing the dipole, orienting the metallic SWNTs, and exposing the SWNTs to a magnetic field with a spatial gradient so that the oriented metallic SWNTs drift in the magnetic field gradient and thereby becomes spatially separated from the semiconducting SWNTs. An apparatus for the process of sorting SWNTs is disclosed.

公开(公告)号：US07943651B2

公开(公告)日：2011-05-17

申请号：US11736606

申请日：2007-04-18

Applicant: Keith Biggadike ,  Anthony William James Cooper ,  David House ,  Iain McFarlane McLay

Inventor： Keith Biggadike ,  Anthony William James Cooper ,  David House ,  Iain McFarlane McLay

IPC: C07D231/56 ,  A01N43/56

CPC classification number: C07D403/10 ,  C07D231/56

Abstract: The present invention provides compounds of formula (I): pharmaceutical compositions comprising the compounds and the use of the compounds for the manufacture of a medicament, particularly for the treatment of inflammation and/or allergic conditions.

Abstract translation: 本发明提供式（I）化合物：包含该化合物的药物组合物和该化合物在制备药物中的用途，特别是用于治疗炎症和/或过敏性疾病。

公开(公告)号：US20100040380A1

公开(公告)日：2010-02-18

申请号：US12518767

申请日：2007-12-17

Applicant: Andrew Charles Lewin ,  David Arthur Orchard ,  Martin James Cooper

Inventor： Andrew Charles Lewin ,  David Arthur Orchard ,  Martin James Cooper

IPC: H04B10/00

CPC classification number: G06K9/74 ,  G06E3/00 ,  H04Q11/0005 ,  H04Q2011/003 ,  H04Q2011/0032 ,  H04Q2011/0035

Abstract: An optical correlation apparatus is described which forms first and second parallel optical signals in response to a serial input data stream. The first parallel optical signal is arranged to have bright pulses represent binary 1 and the second parallel optical signal is arranged to have bright pulses represent binary 0. A channel select means, such as an optical switch or amplitude modulators deselects or blocks channels in the first parallel optical signal which correspond to binary 1 in a reference data string and also deselects or blocks channels in the second parallel optical signal which correspond to binary 0 in the reference data string. The remaining optical signals are combined at one or more detectors. Where the input data matches the reference data string each bright pulse in the first and second parallel optical signals is deselected and the detector registers zero intensity. However when there is any mismatch at least one channel will pass a bright pulse to the detector. An instance of zero intensity can therefore be used as an indication of pattern match.

Abstract translation: 描述了一种光学相关装置，其响应于串行输入数据流而形成第一和第二并行光信号。 第一并行光信号被布置成具有表示二进制1的亮脉冲，并且第二并行光信号被布置为具有表示二进制0的亮脉冲。诸如光开关或幅度调制器之类的通道选择装置在第一 平行光信号，其对应于参考数据串中的二进制1，并且还取消选择或阻止与参考数据串中的二进制0对应的第二并行光信号中的信道。 剩余的光信号在一个或多个检测器处组合。 在输入数据与参考数据串匹配的情况下，取消选择第一和第二并行光信号中的每个亮脉冲，并且检测器记录零强度。 然而，当存在任何失配时，至少一个通道将通过明亮的脉冲到检测器。 因此，零强度的实例可以用作模式匹配的指示。

公开(公告)号：US20100016331A1

公开(公告)日：2010-01-21

申请号：US12444719

申请日：2007-10-10

Applicant: Keith Biggadike ,  Anthony William James Cooper ,  David House ,  Iain McFarlane McLay

Inventor： Keith Biggadike ,  Anthony William James Cooper ,  David House ,  Iain McFarlane McLay

IPC: A61K31/497 ,  C07D231/56 ,  A61K31/415 ,  C07D403/08 ,  C07D401/08 ,  A61K31/445

CPC classification number: C07D231/56 ,  A61K45/06 ,  C07D401/10 ,  C07D403/10 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

Abstract: The present invention provides compounds of formula (I): a process for their preparation, pharmaceutical compositions comprising the compounds and the preparation of said compositions, intermediates and use of the compounds for the manufacture of a medicament for therapeutic treatment, particularly for the treatment of inflammation, allergy and/or skin disease.

公开(公告)号：US07528148B2

公开(公告)日：2009-05-05

申请号：US10540371

申请日：2003-12-19

Applicant: David George Allen ,  Diane Mary Coe ,  Caroline Mary Cook ,  Anthony William James Cooper ,  Michael Dennis Dowle ,  Christopher David Edlin ,  Julie Nicole Hamblin ,  Martin Redpath Johnson ,  Paul Spencer Jones ,  Mika Kristian Lindvall ,  Charlotte Jane Mitchell ,  Alison Judith Redgrave

Inventor： David George Allen ,  Diane Mary Coe ,  Caroline Mary Cook ,  Anthony William James Cooper ,  Michael Dennis Dowle ,  Christopher David Edlin ,  Julie Nicole Hamblin ,  Martin Redpath Johnson ,  Paul Spencer Jones ,  Mika Kristian Lindvall ,  Charlotte Jane Mitchell ,  Alison Judith Redgrave

IPC: C07D471/02 ,  C07D491/02 ,  C07D498/02 ,  C07D513/02 ,  C07D515/02 ,  A01N43/42 ,  A61K31/44

CPC classification number: C07D471/04

Abstract: The invention relates to a compound of formula (I) or a salt thereof: wherein: R1 is C1-4alkyl, C1-3fluoroalkyl or —(CH2)2OH; R2 is a hydrogen atom (H), methyl or C1fluoroalkyl; R3a is a hydrogen atom (H) or C1-3alkyl; R3 is optionally substituted branched C3-6alkyl, optionally substituted C3-8cycloalkyl, optionally substituted mono-unsaturated-C5-7cycloalkenyl, optionally substituted phenyl, or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc): in which n1 and n2 independently are 1 or 2; and Y is O, S, SO2, or NR4; and wherein Het is of sub-formula (i), (ii), (iii), (iv) or (v): The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.

Abstract translation: 本发明涉及式（I）化合物或其盐：其中：R 1为C 1-4烷基，C 1-3氟烷基或 - （CH 2）2 OH; R2是氢原子（H），甲基或C1-4烷基; R3a是氢原子（H）或C1-3烷基; R 3是任选取代的支链C 3-6烷基，任选取代的C 3-8环烷基，任选取代的单不饱和C 5-7环烯基，任选取代的苯基或任选取代的亚式（aa），（bb）或（cc） 其中n1和n2独立地为1或2; Y是O，S，SO 2或NR 4; 并且其中Het为亚式（i），（ii），（iii），（iv）或（v）：所述化合物是磷酸二酯酶（PDE）抑制剂，特别是PDE4抑制剂。 还提供了式（I）化合物或其药学上可接受的盐在制备用于治疗和/或预防哺乳动物例如人的炎性和/或过敏性疾病的药物中的用途， 例如慢性阻塞性肺疾病（COPD），哮喘或过敏性鼻炎。