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公开(公告)号:US20050184385A1
公开(公告)日:2005-08-25
申请号:US10784756
申请日:2004-02-23
申请人: John Brennan , Joseph Freund , Sujal Shah , Richard Shanaman
发明人: John Brennan , Joseph Freund , Sujal Shah , Richard Shanaman
IPC分类号: H01L23/10 , H01L23/12 , H01L23/34 , H01L23/367
CPC分类号: H01L23/3677 , H01L2924/0002 , H01L2924/10158 , H01L2924/00
摘要: A semiconductor device includes a substrate and an active region formed in the substrate proximate an upper surface of the substrate. The active region includes at least one circuit element formed therein. At least one channel is formed in a back surface of the substrate opposite the upper surface of the substrate, the channel being formed proximate the active region. The channel is substantially filled with one or more layers of a thermally conductive material and configured so as to provide a thermal conduction path for conducting heat away from the active region.
摘要翻译: 半导体器件包括衬底和形成在衬底中的靠近衬底的上表面的有源区。 有源区包括形成在其中的至少一个电路元件。 在衬底的与衬底的上表面相对的背表面中形成至少一个沟道,该沟道靠近有源区形成。 通道基本上填充有一层或多层导热材料,并且构造成提供用于将热量从有源区域传导出来的热传导路径。
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公开(公告)号:US20050109270A1
公开(公告)日:2005-05-26
申请号:US10611505
申请日:2003-06-30
申请人: John Brennan , Michael Price , Juergen Tinz , Liming Wang
发明人: John Brennan , Michael Price , Juergen Tinz , Liming Wang
IPC分类号: C30B29/12 , C30B1/00 , C30B9/00 , C30B11/00 , C30B17/00 , C30B21/02 , C30B28/06 , C30B33/00 , C30B33/02
CPC分类号: C30B33/00 , C30B29/12 , Y10T117/10 , Y10T117/1016 , Y10T117/1024
摘要: A method of making below 250-nm UV light transmitting optical fluoride lithography crystals includes applying heat along a shortest path of conduction of a selected optical fluoride crystal, heating the optical fluoride crystal to an annealing temperature, holding the temperature of the optical fluoride crystal at the annealing temperature, and gradually cooling the optical fluoride crystal to provide a low-birefringence optical fluoride crystal for transmitting below 250-nm UV light.
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公开(公告)号:US20050053954A1
公开(公告)日:2005-03-10
申请号:US10698492
申请日:2003-11-03
申请人: John Brennan , Nicholas Rupcich
发明人: John Brennan , Nicholas Rupcich
CPC分类号: B01J19/0046 , B01J2219/00387 , B01J2219/00527 , B01J2219/00596 , B01J2219/00644 , B01J2219/00659 , B01J2219/00725 , C40B40/10 , C40B60/14 , G01N33/5436
摘要: The present invention involves a multicomponent protein microarray comprising two or more components of a protein-based system entrapped within spots of a biomolecule compatible matrix arranged on a surface. Also included are methods of using the microarray for multicomponent analysis along with kits and machinery comprising the microarray.
摘要翻译: 本发明涉及一种多组分蛋白微阵列,其包含位于表面上的生物分子相容性基质的斑点内的基于蛋白质的系统的两种或多种组分。 还包括使用微阵列进行多组分分析的方法以及包含微阵列的试剂盒和机械。
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公开(公告)号:US06691746B2
公开(公告)日:2004-02-17
申请号:US10353007
申请日:2003-01-29
申请人: John Brennan , Roger Matthews , Stephen Metcalf
发明人: John Brennan , Roger Matthews , Stephen Metcalf
IPC分类号: B65B304
CPC分类号: B65B31/003
摘要: A filling apparatus for, a filling system for and a method of introducing into a container a suspension or solution of a substance, in particular a pharmaceutical substance, in a propellant under pressure, the filling apparatus comprising: a main body (4) including a passageway (20) for communicating, in use, with a valve stem (144) extending from a head (141) of a body (139) of a container (138); a fill actuator (7) comprising a filling valve assembly (29) in communication with the passageway (20) for selectively introducing thereinto propellant under pressure containing a substance in a suspension or solution; an exhaust actuator (10) comprising an exhaust valve assembly (48) in communication with the passageway (20) for selectively exhausting therefrom propellant under pressure containing substance; and a container-engaging body (16) in communication with the passageway (20) for receiving, in use, the head (141) of the body (139) of the container (138), the container-engaging body (16) including a chamber (116) of greater radial dimension than the valve stem (144) of the container (138) into which, in use, extends the valve stem (144) of the container (138) and a conduit (126) in communication with the chamber (116) for feeding a pressurised fluid thereto.
摘要翻译: 一种用于填充装置的灌装装置,以及一种在压力下向推进剂中引入物质特别是药物的悬浮液或溶液的容器的方法,所述填充装置包括:主体(4),包括: 通道(20),用于在使用中与从容器(138)的主体(139)的头部(141)延伸的阀杆(144)连通; 填充致动器(7)包括与所述通道(20)连通的填充阀组件(29),用于在包含悬浮液或溶液中的物质的压力下选择性地将推进剂引入其中; 排气致动器(10),包括与所述通道(20)连通的排气阀组件(48),用于在包含物质的压力下选择性地排出其中的推进剂; 以及与所述通道(20)连通的容器接合体(16),用于在使用中容纳所述容器(138)的主体(139)的头部(141),所述容器接合体(16)包括 具有比所述容器(138)的阀杆(144)更大的径向尺寸的腔室(116),其中在使用中延伸所述容器(138)的阀杆(144)和与所述容器(138)连通的导管(126) 用于将加压流体供给到其的腔室(116)。
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公开(公告)号:US5537538A
公开(公告)日:1996-07-16
申请号:US166969
申请日:1993-12-15
申请人: Joseph P. Bratt , John Brennan , Peter Y. Hsu , Chandra S. Joshi , William A. Huffman , Monica R. Nofal , Paul Rodman , Joseph T. Scanlon , Man K. Tang
发明人: Joseph P. Bratt , John Brennan , Peter Y. Hsu , Chandra S. Joshi , William A. Huffman , Monica R. Nofal , Paul Rodman , Joseph T. Scanlon , Man K. Tang
IPC分类号: D06M13/46 , C11D1/04 , C11D1/62 , C11D1/645 , C11D1/65 , C11D1/72 , C11D1/835 , C11D3/00 , D06M20060101 , D06M13/02 , D06M13/184 , D06M13/188 , D06M13/322 , D06M13/463 , G06F9/38 , G06F11/36 , G06F11/34 , G06F9/30
CPC分类号: G06F11/3664 , G06F9/3836 , G06F9/3838 , G06F9/3857 , G06F9/3861 , G06F9/3867 , G06F9/3885
摘要: A processor system that is switchable between a normal mode of operation without precise floating point exceptions and a debug mode of operation with precise floating point exceptions. The processor system includes a dispatch for dispatching integer and floating point instructions, an integer unit having a multi-stage integer pipeline for executing the integer instructions, and a floating point unit having a multi-stage floating point pipeline for executing the floating point instructions. The system begins operation in the normal mode, and upon receipt of an instruction to "switch to debug mode," the processor switches to the debug mode of operation with precise exceptions. In the debug mode, once a floating point instruction has been dispatched, all other instructions are prevented from being committed until the system determines whether the floating point instruction generates an exception. Thus, permitting the system to signal precise exceptions when not in the normal mode.
摘要翻译: 处理器系统,可在正常操作模式之间切换,无需精确的浮点异常,以及具有精确浮点异常的调试操作模式。 处理器系统包括调度整数和浮点指令的调度,具有用于执行整数指令的多级整数流水线的整数单元,以及具有用于执行浮点指令的多级浮点流水线的浮点单元。 系统在正常模式下开始运行,并且在接收到“切换到调试模式”的指令时,处理器切换到调试操作模式,具有精确的例外。 在调试模式下,一旦调度了浮点指令,就会阻止所有其他指令被提交,直到系统确定浮点指令是否产生异常。 因此,允许系统在不处于正常模式时发出精确异常。
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56.
公开(公告)号:US20130330754A1
公开(公告)日:2013-12-12
申请号:US13912662
申请日:2013-06-07
申请人: John Brennan , Zakir Hossain
发明人: John Brennan , Zakir Hossain
IPC分类号: C12Q1/34
CPC分类号: C12Q1/34 , G01N2333/938
摘要: The present application is directed to a novel approach for rapid, selective and sensitive detection of heavy metals using a solid-phase bioactive lab-on-paper sensor that is ink-jet printed with sol-gel entrapped reagents to allow colorimetric visualization of the enzymatic activity. The bioactive paper assay is able to detect a range of heavy metals, either alone or as mixtures, in as little as 10 min. The paper-based assay was immune to interferences from non-toxic metal ions such as Na+ or K+, could be used to detect heavy metals that were spiked into tap water or lake water, and provided quantitative data that was in agreement with values obtained by atomic absorption. The paper-based sensor is of value for rapid, on-site screening of trace levels of heavy metals in resource limited areas and developing countries.
摘要翻译: 本申请涉及一种用于使用固相生物活性实验室纸传感器快速,选择性和灵敏检测重金属的新方法,其中喷墨印刷有溶胶 - 凝胶夹带的试剂,以允许酶的比色可视化 活动。 生物活性纸测定能够在短短10分钟内单独或作为混合物检测一系列重金属。 基于纸张的测定法免于来自无毒金属离子(如Na +或K +)的干扰,可用于检测掺入自来水或湖泊水中的重金属,并提供与通过以下方法获得的值相符的定量数据: 原子吸收。 基于纸张的传感器对于资源有限的地区和发展中国家的痕量重金属进行快速,现场筛选是有价值的。
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公开(公告)号:US20130074142A1
公开(公告)日:2013-03-21
申请号:US13233032
申请日:2011-09-15
IPC分类号: H04L9/32
CPC分类号: H04L63/20 , G06F21/31 , G06F21/6218 , G06F21/6245 , H04L63/105
摘要: Policies are applied to specific data rather than to an entire computing device that contains the specific data. Access to the specific data is controlled by the policies utilizing various password or other authentication credential requirements, selective data caching, data transmission, temporary data storage, and/or pre-defined conditions under which the specific data is to be erased or rendered inaccessible. Policies may be defined by an administrator and pushed to a mobile computing device, whereat the policies are enforced.
摘要翻译: 策略应用于特定数据,而不是包含特定数据的整个计算设备。 使用各种密码或其他认证凭证要求,选择性数据缓存,数据传输,临时数据存储和/或预定义条件来控制特定数据的访问,特定数据将被删除或呈现为不可访问的条件。 策略可以由管理员定义,并被推送到移动计算设备,在这些设备上执行策略。
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公开(公告)号:US20120157424A1
公开(公告)日:2012-06-21
申请号:US13408760
申请日:2012-02-29
申请人: John Brennan , Earl E. Sands , Rex Horton , Zurab Bebia
发明人: John Brennan , Earl E. Sands , Rex Horton , Zurab Bebia
CPC分类号: A61K31/565 , A61K9/0014 , A61K9/06 , A61K31/56
摘要: Described are estradiol-containing pharmaceutical compositions and, and methods using the same to alleviate menopause-related symptoms, such as hot flushes, by topically administering estradiol at low effective doses.
摘要翻译: 描述的是含雌二醇的药物组合物,以及使用该组合物的方法,通过以低有效剂量局部施用雌二醇来减轻更年期相关症状,例如热潮红。
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公开(公告)号:US07918773B2
公开(公告)日:2011-04-05
申请号:US12081579
申请日:2008-04-17
申请人: John Brennan , Edward Charles Leach
发明人: John Brennan , Edward Charles Leach
IPC分类号: A63B21/04
CPC分类号: A63B21/04 , A63B21/0724 , A63B21/4035 , A63B21/4043 , A63B23/03525 , A63B23/12 , A63B23/1209 , A63B2069/068 , A63B2208/0204 , A63B2208/0233 , A63B2209/08 , A63B2210/50
摘要: An exercise device, comprising an elongate member which has a pair of end regions with a pair of opposed end portions. Each end portion has a body wherein each body has one of a pair of opposed first end faces and at least a pair of first weighted segments. Each of the weighted segments is removably attachable to the elongate member and/or a corresponding end portion in an operative position. Each first weighted segment also has a second end face which abuts the first end face in the operative position. Each body has a first exterior surface region including and anchor portion for attaching thereto at least one elongate resilient portion at one end of the resilient portion and to a fixed object at the opposing end. A method for using the device is also provided.
摘要翻译: 一种锻炼装置,包括细长构件,该细长构件具有一对具有一对相对端部的端部区域。 每个端部具有主体,其中每个主体具有一对相对的第一端面和至少一对第一加权段中的一个。 每个加权段可移除地附接到细长构件和/或在可操作位置的相应端部。 每个第一加权段还具有在操作位置邻接第一端面的第二端面。 每个主体具有包括第一外表面区域和锚定部分,用于在弹性部分的一端附接至少一个细长的弹性部分,并在相对的端部与固定物体相连。 还提供了一种使用该装置的方法。
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公开(公告)号:US07672411B2
公开(公告)日:2010-03-02
申请号:US10291984
申请日:2002-11-12
CPC分类号: H04B1/16 , H03D1/04 , H03D1/06 , H03D1/2245 , H03D3/007
摘要: A radio receiver comprising: an antenna for receiving a radio frequency signal amplitude modulated with an audio frequency signal; a digitizer for periodically sampling the radio frequency signal and generating a digital reception signal representative of the amplitude of the radio frequency signal; and a demodulator for demodulating the digital reception signal to generate a representation of the audio frequency signal.
摘要翻译: 一种无线电接收机,包括:用于接收用音频信号幅度调制的射频信号的天线; 数字转换器,用于周期性地对射频信号进行采样并产生表示射频信号振幅的数字接收信号; 以及用于解调数字接收信号以产生音频信号的表示的解调器。
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