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    Electrochemical test device and related methods
    52.
    发明授权
    Electrochemical test device and related methods 失效

    公开(公告)号：US07115362B2

    公开(公告)日：2006-10-03

    申请号：US11287522

    申请日：2005-11-23

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest

    IPC分类号： C12Q1/00

    CPC分类号： C12Q1/001 ,  C12Q1/004 ,  C12Q1/006 ,  Y10S435/817 ,  Y10S436/805 ,  Y10S436/806

    摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode. The test device electrodes can be constructed on a flexible film substrate, such as a polymeric film or a metal foil coated with a non-conductive coating.

    Device for determination of an analyte in a body fluid using small sample sizes
    54.
    发明授权
    Device for determination of an analyte in a body fluid using small sample sizes 失效
    用于使用小样本大小来测定体液中的分析物的装置

    公开(公告)号：US06544474B2

    公开(公告)日：2003-04-08

    申请号：US09755362

    申请日：2001-01-05

    申请人： Joel S. Douglas

    发明人： Joel S. Douglas

    IPC分类号： G01N2101

    CPC分类号： G01N33/528 ,  B01L3/5023 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/069 ,  B01L2300/0838 ,  B01L2400/0406 ,  G01N21/8483

    摘要： Devices and methods for utilizing dry chemistry dye indicator systems for body fluid analysis such as glucose level in whole blood are provided by incorporating an indicator in a bibulous matrix contained inside a hollow fiber capillary tube adapted to wick the fluid sample into the tube to wet the matrix and indicator system. The devices also enable visual or meter reading of the indicator by positioning the hollow fiber capillary tube in a housing having an optical opening adapted for receiving light form a source and directing the light to the capillary tube and for directing the light reflected therefrom to a detector. An advantage for the individual user is the small fluid, e.g., blood sample required, which enables the user to avoid using finger tip sticks for samples. Another aspect of the device provides a determination of and correction for hematocrit level in whole blood in combination with indicator indication of analyte concentration. The devices provided are low cost due to efficient manufacturing.

    摘要翻译： 使用干化学染料指示剂系统进行体液分析的装置和方法，例如全血中的葡萄糖水平，通过将指示剂并入包含在中空纤维毛细管内的吸水性基质中，适于将流体样品吸入管中来润湿 矩阵和指标体系。 所述装置还能够通过将中空纤维毛细管定位在具有光学开口的壳体中来使得能够对指示器进行视觉或抄表读取，该光学开口适于接收来自光源的光并将光引导到毛细管并将其从其反射的光引导到检测器 。 个体用户的优点是小的流体，例如所需的血液样本，这使得用户能够避免使用指尖棒来进行样品。 该装置的另一方面提供了全血中血细胞比容水平的确定和校正，并结合分析物浓度的指标指标。 所提供的设备由于高效的制造而成本低廉。