公开(公告)号：US06593088B1

公开(公告)日：2003-07-15

申请号：US09830401

申请日：2001-06-28

申请人： Isao Saito ,  Kenzo Fujimoto ,  Shigeo Matsuda

发明人： Isao Saito ,  Kenzo Fujimoto ,  Shigeo Matsuda

IPC分类号： C12Q168

CPC分类号： C07H21/00 ,  C07H19/06

摘要： As a novel technique, which gives selective photoligation in high yield and enables ligated site-specific photocleavage, as well as free and reversible control of photoligation and photocleavage, a reversible photoligating nucleic acid of the following formula (1): is used to control photoligation and photocleavage to and from biofunctional polymers freely.

摘要翻译： 作为一种新技术，其以高产率提供选择性光连接并且能够进行连接位点特异性光切割，以及游离和可逆控制光切割和光切割，使用下式（1）的可逆光致核酸来控制光连接 并自由地从生物官能聚合物进行光切割。

公开(公告)号：US06497611B2

公开(公告)日：2002-12-24

申请号：US09767881

申请日：2001-01-24

申请人： Toshimichi Sakurada ,  Yasutoshi Fujita ,  Masao Yamaguchi ,  Kazuo Orii ,  Isao Saito

发明人： Toshimichi Sakurada ,  Yasutoshi Fujita ,  Masao Yamaguchi ,  Kazuo Orii ,  Isao Saito

IPC分类号： B24B4900

CPC分类号： B24B53/017 ,  B24B37/048 ,  G11B5/3103 ,  G11B5/3116 ,  G11B5/3163

摘要： Disclosed is a method of polishing a magnetic head slider whereby a by-processed step can be easily reduced. An air bearing surface of the magnetic head slider is polished with setting a bar that includes the magnetic head slider where a thin film magnetic head element is formed to reciprocate in a radius direction of a polishing plate, as well as rotating the polishing plate having a polishing surface. Polishing steps include a first polishing step of performing a height polish while rotating the polishing plate at a first velocity, and a second polishing step of performing a finishing polish while rotating the polishing plate at a second velocity sufficiently lower than the first velocity. The second velocity at the second polishing step is set so that an average linear velocity in the direction of the rotation of the polishing plate is equal to or lower than 0.032 m/s (preferably equal to or lower than 0.008 m/s). Consequently, the by-processed step that is generated on the air bearing surface of the magnetic head slider is reduced.

公开(公告)号：US06383239B1

公开(公告)日：2002-05-07

申请号：US09522115

申请日：2000-03-09

申请人： Yasuyuki Suzuki ,  Tomohiro Kaku ,  Isao Saito ,  Kazuya Orii ,  Yasutoshi Fujita ,  Masao Yamaguchi ,  Masahiro Sasaki

发明人： Yasuyuki Suzuki ,  Tomohiro Kaku ,  Isao Saito ,  Kazuya Orii ,  Yasutoshi Fujita ,  Masao Yamaguchi ,  Masahiro Sasaki

IPC分类号： C09K314

CPC分类号： C09G1/02 ,  C09K3/1472

摘要： The present invention relates to a free abrasive slurry composition which is advantageously used in uniform grinding of a composite material composed of a plurality of materials each having different hardness, without causing selective grinding. The free abrasive slurry composition contains abrasive particles, an anti-abrasion agent as an anti-selective grinding agent and a dispersion medium and the anti-abrasive agent is a compound containing one or both of sulfur and phosphorus or hydroxyl group(s) in the molecular chain.

摘要翻译： 本发明涉及一种自由磨料浆料组合物，其有利地用于均匀研磨由多种具有不同硬度的材料组成的复合材料，而不会引起选择性研磨。 游离研磨剂浆料组合物含有磨料颗粒，作为抗选择性研磨剂的抗磨剂和分散介质，抗磨剂是含有硫和磷或羟基中的一个或两个的化合物 分子链。

公开(公告)号：US5276560A

公开(公告)日：1994-01-04

申请号：US711891

申请日：1991-06-07

申请人： Isao Saito ,  Keitaro Yamashita

发明人： Isao Saito ,  Keitaro Yamashita

IPC分类号： G11B20/12 ,  G11B5/008 ,  G11B27/032 ,  G11B27/036 ,  G11B27/28 ,  G11B27/30 ,  H04N5/783 ,  H04N5/928 ,  H04N5/93 ,  G11B5/02

CPC分类号： H04N5/928 ,  G11B27/036 ,  G11B27/3027 ,  G11B5/0086 ,  H04N5/93 ,  G11B2220/90 ,  G11B27/032 ,  H04N5/783

摘要： A video tape recording apparatus includes a rotary magnetic head for scanning skewed recording tracks on a video tape, a device for recording a video signal in each of the recording tracks by the rotary magnetic head, a device for providing a first guard band area in each of the recording tracks next to the video signal recorded in the respective recording track, a device for recording a first audio signal next to the first guard band area by the rotary magnetic head, a device for providing a second guard band area next to the first audio signal in each of the recording tracks with the second guard band area having a length different from the length of the first guard band area, a device for recording a second audio signal next to the second guard band area by the rotary magnetic head, and a device for recording an index signal in a longer one of the first and second guard band areas by the rotary magnetic head.

摘要翻译： 录像带记录装置包括用于扫描录像带上的倾斜记录磁道的旋转磁头，用于通过旋转磁头在每个记录磁道中记录视频信号的装置，用于在每个记录磁道中提供第一保护带区域的装置 记录在相应记录磁道中的视频信号旁边的记录磁迹，用于通过旋转磁头记录第一保护带区域旁边的第一音频信号的装置，用于提供第二保护带区域的设备， 每个记录道中的音频信号，其中第二保护带区具有与第一保护带区的长度不同的长度;用于通过旋转磁头记录第二保护带区旁边的第二音频信号的装置，以及 用于通过旋转磁头在第一和第二保护带区域的较长的一个区域中记录索引信号的装置。

公开(公告)号：US5196439A

公开(公告)日：1993-03-23

申请号：US825423

申请日：1992-01-24

申请人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Norio Karibe ,  Isao Saito ,  Kunizo Higurashi ,  Masahiro Yonaga ,  Takeru Kaneko ,  Takahiro Nakazawa ,  Masataka Ueno ,  Kiyomi Yamatsu ,  Kohshi Ueno ,  Masuhiro Ikeda

发明人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Norio Karibe ,  Isao Saito ,  Kunizo Higurashi ,  Masahiro Yonaga ,  Takeru Kaneko ,  Takahiro Nakazawa ,  Masataka Ueno ,  Kiyomi Yamatsu ,  Kohshi Ueno ,  Masuhiro Ikeda

IPC分类号： C07D211/14 ,  C07D211/18 ,  C07D211/32 ,  C07D211/46 ,  C07D211/58 ,  C07D223/04 ,  C07D401/12

CPC分类号： C07D401/12 ,  C07D211/14 ,  C07D211/18 ,  C07D211/32 ,  C07D211/46 ,  C07D211/58 ,  C07D223/04

摘要： A cyclic amine is defined by the formula: ##STR1## in which A is naphthyl, phenyl, quinolyl or alkyl, X is a group containing carbonyl, n is 2 or 3 and B is alkyl, halogen, phenyl or --YZ, Y being --O--, --CO-- or --NH--, Z being phenyl, naphthyl, pyridyl, alkyl or cycloalkyl. It is useful to treat mental symptoms associated with a cerebrovascular disease.

摘要翻译： 环胺由下式定义：其中A为萘基，苯基，喹啉基或烷基，X为含羰基的基团，n为2或3，B为烷基，卤素，苯基或-YZ ，Y为-O-，-CO-或-NH-，Z为苯基，萘基，吡啶基，烷基或环烷基。 治疗与脑血管病相关的精神症状是有用的。

公开(公告)号：US5010188A

公开(公告)日：1991-04-23

申请号：US167152

申请日：1988-03-16

申请人： Hiroshi Yamauchi ,  Isao Sugiyama ,  Isao Saito ,  Seiichiro Nomoto ,  Takashi Kamiya ,  Yoshimasa Machida ,  Shigeto Negi

发明人： Hiroshi Yamauchi ,  Isao Sugiyama ,  Isao Saito ,  Seiichiro Nomoto ,  Takashi Kamiya ,  Yoshimasa Machida ,  Shigeto Negi

IPC分类号： C07D471/08 ,  C07D501/46

CPC分类号： C07D471/08

摘要： Described herein is a cephem derivative represented by the general formula: ##STR1## wherein n stands for 1 or 2, Y stands for CH or nitrogen atom, R.sub.1 represents a lower hydrocarbon group or a carboxyl-substituted, a carbamoyl-substituted, or a cyclopropyl-substituted lower alkyl group, and R.sub.2 denotes hydroxyl group, a lower alkyl group, a hydroxy-substituted lower alkyl group, or carbamoyl group. The derivative is useful as an antibacterial composition. Also described herein are processes for the production of the derivative, antibacterial composition, intermediate of the derivative and process for the production thereof.

公开(公告)号：US5008260A

公开(公告)日：1991-04-16

申请号：US167153

申请日：1988-03-16

申请人： Hiroshi Yamauchi ,  Isao Sugiyama ,  Isao Saito ,  Seiichiro Nomoto ,  Takashi Kamiya ,  Yoshimasa Machida ,  Shigeto Negi

发明人： Hiroshi Yamauchi ,  Isao Sugiyama ,  Isao Saito ,  Seiichiro Nomoto ,  Takashi Kamiya ,  Yoshimasa Machida ,  Shigeto Negi

IPC分类号： C07D471/08 ,  C07D501/46

CPC分类号： C07D471/08

摘要： Described herein is a cephem derivative represented by the general formula: ##STR1## wherein n stands for 1 or 2, Y stands for CH or nitrogen atom, R.sub.1 represents a lower hydrocarbon group or a carboxyl-substituted, a carbamoyl-substituted, or a cyclopropyl-substituted lower alkyl group, and R.sub.2 denotes hydroxyl group, a lower alkyl group, a hydroxy-substituted lower alkyl group, or carbamoyl group. The derivative is useful as an antibacterial agent. Also described herein are processes for the production of the derivative, antibacterial composition, intermediate of the derivative and process for the production thereof.

公开(公告)号：US4900407A

公开(公告)日：1990-02-13

申请号：US355814

申请日：1989-05-17

申请人： Isao Saito ,  Teruo Matsuura ,  Hideyuki Ikehira

发明人： Isao Saito ,  Teruo Matsuura ,  Hideyuki Ikehira

IPC分类号： B01J19/12 ,  C07B31/00 ,  C07B37/06 ,  C07C1/20 ,  C07C67/00 ,  C07F7/18 ,  C07H19/16 ,  C25B3/04

CPC分类号： C07H19/16 ,  C07C1/20 ,  C25B3/04

摘要： In a method for deoxygenating the secondary and/or tertiary OH group(s) in an alcohol having such OH group(s), a characteristic feature thereof is that the alcohol having the OH group(s) is first converted into a substituted or unsubstituted benzoate derivative, and the benzoate derivative is then subjected to a photocatalytic reaction in the presence of an electron donor or to an electrode reaction in the presence of an electrolyte, whereby the desired compound in which the OH group(s) has (have) been selectively deoxygenated can be obtained in a high yield on an industrial scale.

摘要翻译： 在具有这种OH基团的醇中使二级和/或叔级OH基团脱氧的方法中，其特征在于具有OH基团的醇首先被转化为取代或未取代的 苯甲酸酯衍生物和苯甲酸酯衍生物在电子给体的存在下进行光催化反应或在电解质存在下进行电极反应，由此得到所需的OH基团所具有的化合物 可以以工业规模的高产率获得选择性脱氧。

公开(公告)号：US4402966A

公开(公告)日：1983-09-06

申请号：US252674

申请日：1981-04-09

申请人： Motosuke Yamanaka ,  Isao Saito ,  Kiyomi Yamatsu ,  Takako Fujimoto

发明人： Motosuke Yamanaka ,  Isao Saito ,  Kiyomi Yamatsu ,  Takako Fujimoto

IPC分类号： A61K31/415 ,  A61K31/445 ,  C07D233/54 ,  C07D233/56 ,  C07D233/60 ,  C07D233/61 ,  C07D521/00

CPC分类号： C07D233/64 ,  A61K31/415 ,  A61K31/445 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： An imidazole compound of the formula: ##STR1## wherein R.sub.1 is lower alkyl, R.sub.2 is hydrogen or lower alkyl, and R.sub.3, R.sub.4 and R.sub.5 are hydrogen, lower alkyl, trifluoromethyl, amino, mono- or di-lower alkylamino, heterocyclic amino, halogen or ##STR2## (in which R.sub.6 is hydrogen, lower alkyl or lower alkylsulfonyl, A is carbonyl or sulfonyl, and R.sub.7 is lower alkyl, halogenated lower alkyl, mono- or di-lower alkylamino, mono- or di-lower alkylaminoalkyl, unsubstituted phenyl or phenyl having halogen, lower alkyl, lower alkoxy or trifluoromethyl, phenylamino or phenylamino having halogen, lower alkyl, lower alkoxy or trifluoromethyl); and their pharmaceutically acceptable acid addition salts.The compounds are useful for treating patients suffering from depression.

摘要翻译： 下式的咪唑化合物：其中R1是低级烷基，R2是氢或低级烷基，R3，R4和R5是氢，低级烷基，三氟甲基，氨基，一或二低级烷基氨基，杂环氨基， 卤素或（其中R6是氢，低级烷基或低级烷基磺酰基，A是羰基或磺酰基，R7是低级烷基，卤代低级烷基，一或二低级烷基氨基，一或二低级烷基氨基烷基， 未取代的苯基或具有卤素，低级烷基，低级烷氧基或三氟甲基的苯基，苯基氨基或具有卤素，低级烷基，低级烷氧基或三氟甲基的苯基氨基）; 及其药学上可接受的酸加成盐。 该化合物可用于治疗患有抑郁症的患者。

公开(公告)号：US4285941A

公开(公告)日：1981-08-25

申请号：US142160

申请日：1980-04-14

申请人： Yoshimasa Machida ,  Isao Saito ,  Seiichiro Nomoto ,  Shigeto Negi ,  Takeo Kanai ,  Kyosuke Kitoh ,  Kanemasa Katsu ,  Yukio Ohya ,  Takeshi Nagasu

发明人： Yoshimasa Machida ,  Isao Saito ,  Seiichiro Nomoto ,  Shigeto Negi ,  Takeo Kanai ,  Kyosuke Kitoh ,  Kanemasa Katsu ,  Yukio Ohya ,  Takeshi Nagasu

IPC分类号： C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D311/22 ,  C07D501/36

CPC分类号： C07D311/22

摘要： Novel cephalosporin compounds of the general formula: ##STR1## wherein R.sub.1 represents a substituted or unsubstituted nitrogen-containing heterocyclic-thio group, R.sub.2 represents hydrogen or hydroxy, and R.sub.3, R.sub.4 and R.sub.5 each represents hydrogen, hydroxy or acyloxy, and their salts, and processes for the preparation thereof. The novel compounds and their salts have antibacterial activity.

摘要翻译： 新型头孢菌素化合物，其通式如下：其中R 1表示取代或未取代的含氮杂环硫基，R 2表示氢或羟基，R 3，R 4和R 5各自表示氢，羟基或酰氧基， 及其制备方法。 新化合物及其盐具有抗菌活性。