利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

87 条记录 (耗时 0.034 秒)

    Cuffed endoluminal prosthesis
    51.
    发明授权
    Cuffed endoluminal prosthesis 有权
    袖口内腔假体

    公开(公告)号：US06592614B2

    公开(公告)日：2003-07-15

    申请号：US09726431

    申请日：2000-12-01

    申请人： Jay A. Lenker ,  Brian J. Cox ,  Michael A. Evans ,  Steven Weinberg

    发明人： Jay A. Lenker ,  Brian J. Cox ,  Michael A. Evans ,  Steven Weinberg

    IPC分类号： A61F206

    CPC分类号： A61F2/90 ,  A61F2/07 ,  A61F2/844 ,  A61F2/89 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0071

    摘要： The present invention provides controlled expansion endoluminal prostheses and methods for their deployment and expansion. The present stent-grafts generally comprise a radially expansible tubular frame and a plastically expansible liner on the frame. Either the frame or the liner includes a reinforcing element which limits expansion of the stent-graft at a predetermined expanded size. In some embodiments, the reinforcing element restrains the frame, for example, by limiting the circumferential diagonals of perforations on a perforate frame structure. Generally, however, the reinforcing element is included in the liner as circumferentially oriented yarn. A particularly advantageous liner includes composite circumferential yarns having inexpansible fibers wrapped around an expansible fiber, such as a partially oriented yarn, PTFE, or the like.

    摘要翻译： 本发明提供受控的扩张腔内假体及其部署和扩张的方法。 本发明的支架移植物通常包括径向可膨胀的管状框架和框架上的塑性可膨胀的衬垫。 框架或衬里都包括限制扩张器移植物以预定的扩大尺寸的扩张的增强元件。 在一些实施例中，增强元件例如通过限制穿孔框架结构上的穿孔的周向对角线来限制框架。 然而，通常，增强元件作为圆周取向的纱线包括在衬套中。 特别有利的衬里包括具有缠绕在可膨胀纤维（例如部分取向纱线，PTFE等）上的不可消耗纤维的复合周向纱线。

    Vibrating catheter
    55.
    发明授权
    Vibrating catheter 失效
    振动导管

    公开(公告)号：US5713848A

    公开(公告)日：1998-02-03

    申请号：US483071

    申请日：1995-06-07

    申请人： Will R. Dubrul ,  Michael A. Evans

    发明人： Will R. Dubrul ,  Michael A. Evans

    IPC分类号： A61B17/22 ,  A61B19/00 ,  A61F2/06 ,  A61F2/84 ,  A61M29/02 ,  A61B17/32

    CPC分类号： A61M25/104 ,  A61B17/22 ,  A61B17/22012 ,  A61B2017/22067 ,  A61B2017/22084 ,  A61B90/39 ,  A61F2/958 ,  A61M2025/1052 ,  A61M2025/1093

    摘要： The present invention describes a catheter suitable for introduction into a tubular tissue for dissolving blockages in such tissue. The catheter is particularly useful for removing thrombi within blood vessels. In accordance with the preferred embodiments, a combination of vibrating motion and injection of a lysing agent is utilized to break up blockage in vessels. The vessels may be veins, arteries, ducts, intestines, or any lumen within the body that may become blocked from the material that flows through it. As a particular example, dissolution of vascuIar thrombi is facilitated by advancing a catheter through the occluded vessel, the catheter causing a vibrating, stirring action in and around the thrombus usually in combination with the dispensing of a thrombolytic agent such as urokinase into the thrombus. The catheter has an inflatable or expandable member near the distal tip which, when inflated or expanded, prevents the passage of dislodged thrombus around the catheter. The dislodged portions of thrombus are directed through a profusion channel in the catheter, where they are removed by filtration means housed within the perfusion channel before the blood exits the tip of the catheter. Catheters that allow both low frequency (1-1000 Hz) vibratory motion and delivery of such agents to a blockage and a method for using such catheters are disclosed.

    摘要翻译： 本发明描述了一种适于引入管状组织中以将阻塞物溶解在这种组织中的导管。 导管特别适用于去除血管内的血栓。 根据优选实施例，利用振动运动和溶解剂注入的组合来分解血管中的阻塞。 血管可以是静脉，动脉，管道，肠道或身体内可能被流过其的物质阻塞的任何内腔。 作为一个具体实例，血管血栓的溶解通过使导管穿过闭塞的血管而促进，导管通常结合血栓溶解剂如尿激酶分配到血栓中而引起血栓内和周围的振动，搅动作用。 导管在远侧末端附近具有可膨胀或可扩张的构件，当充气或膨胀时，其可以防止移位的血栓在导管周围通过。 血栓的移出部分被引导通过导管中的扩张通道，在血液离开导管末端之前，通过过滤装置将血液从血管中取出。 公开了允许低频（1-1000Hz）振动运动和这种试剂传递到阻塞的导管，以及使用这种导管的方法。

    Vibrating catheter
    57.
    发明授权
    Vibrating catheter 失效
    振动导管

    公开(公告)号：US5380273A

    公开(公告)日：1995-01-10

    申请号：US65470

    申请日：1993-05-19

    申请人： Will R. Dubrul ,  Michael A. Evans

    发明人： Will R. Dubrul ,  Michael A. Evans

    IPC分类号： A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/22084

    摘要： The present invention describes a catheter suitable for introduction into a tubular tissue for dissolving blockages in such tissue. The catheter is particularly useful for removing thrombi within blood vessels. In accordance with the preferred embodiments, a combination of vibrating motion and injection of a lysing agent is utilized to break up blockages in vessels. The vessels may be veins, arteries, ducts, intestines, or any lumen within the body that may become blocked from the material that flows through it. As a particular example, dissolution of vascular thrombi is facilitated by advancing a catheter through the occluded vessel, the catheter causing a vibrating, stirring action in and around the thrombus usually in combination with the dispensing of a thrombolytic agent such as urokinase into the thrombus. The catheter has an inflatable or expandable member near the distal tip which, when inflated or expanded, prevents the passage of dislodged thrombus around the catheter. The dislodged portions of thrombus are directed through a perfusion channel in the catheter, where they are removed by filtration means housed with the perfusion channel before the blood exits the tip of the catheter. Catheters that allow both low frequency (1-1000 Hz) vibratory motion and delivery of such agents to a blockage and a method for using such catheters are disclosed.

    摘要翻译： 本发明描述了一种适于引入管状组织中以将阻塞物溶解在这种组织中的导管。 导管特别适用于去除血管内的血栓。 根据优选实施方案，利用振动运动和裂解剂注射的组合来分解血管中的阻塞。 血管可以是静脉，动脉，管道，肠道或身体内可能被流过其的物质阻塞的任何内腔。 作为一个具体实例，通过使导管穿过闭塞的血管来促进血管血栓的溶解，导管通常结合血栓溶解剂（例如尿激酶）分配到血栓中而引起血栓内和周围的振动，搅动作用。 导管在远侧末端附近具有可膨胀或可扩张的构件，当充气或膨胀时，其可以防止移位的血栓在导管周围通过。 血栓的移出部分被引导通过导管中的灌注通道，在血液离开导管末端之前，通过过滤装置将血液从血管中取出。 公开了允许低频（1-1000Hz）振动运动和这种试剂传递到阻塞的导管，以及使用这种导管的方法。

    APPARATUS AND METHODS FOR CLOT DISSOLUTION
    60.
    发明申请
    APPARATUS AND METHODS FOR CLOT DISSOLUTION 有权
    装置解决方案的装置和方法

    公开(公告)号：US20120283699A1

    公开(公告)日：2012-11-08

    申请号：US13548338

    申请日：2012-07-13

    申请人： Michael A. Evans ,  Denise Demarais ,  Dino De Cicco ,  Kelvin Ning ,  Alexander Khairkhahan ,  Tyler Jon Strang

    发明人： Michael A. Evans ,  Denise Demarais ,  Dino De Cicco ,  Kelvin Ning ,  Alexander Khairkhahan ,  Tyler Jon Strang

    IPC分类号： A61M25/00 ,  A61M1/00 ,  A61M25/10

    CPC分类号： A61M25/0021 ,  A61B17/22 ,  A61B17/320725 ,  A61B17/320758 ,  A61B2017/22067 ,  A61B2017/22084 ,  A61M25/007 ,  A61M25/0105

    摘要： Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.

    摘要翻译： 使用具有注入溶栓剂，抽吸凝块和流体并允许导丝通过的能力的导管实现凝块破裂和溶解。 任选地，导管还可以包括用于在溶栓剂存在下进一步破坏凝块的机械搅拌器。 导管中的流阻器提供输注和/或抽吸主要集中在血管中的凝块治疗区域，同时还提供可选的输液和/或远离治疗区域的抽吸。 在一些实施例中，输注，抽吸和导丝通过共同内腔。 血栓溶解剂如tPA，链激酶或尿激酶在搅拌器与凝块接合的位置处直接释放到凝块中。 以这种方式，药剂的溶栓活性增强，并且凝块的溶解得到改善。