公开(公告)号：US20050282211A1

公开(公告)日：2005-12-22

申请号：US11157629

申请日：2005-06-21

Applicant: Emile Nuwaysir ,  Roland Green ,  Rebecca Selzer ,  Todd Richmond ,  Mark McCormick ,  Steven Smith

Inventor： Emile Nuwaysir ,  Roland Green ,  Rebecca Selzer ,  Todd Richmond ,  Mark McCormick ,  Steven Smith

IPC: C12P19/34 ,  C12Q1/68

CPC classification number: C12Q1/6837 ,  C12Q1/6806

Abstract: The present invention provides methods for optimizing nucleic acid detection assays for use in basic research and clinical research. Specifically, the invention provides a method for empirically optimizing nucleic acid probes by testing them with samples containing genomic DNA with variations in copy number in different regions of the genome. The invention enables the optimization of probes for any hybridization based assay including microarrays, bead-based assays, genotyping assays and RNAi assays.

Abstract translation: 本发明提供用于优化用于基础研究和临床研究的核酸检测测定法的方法。 具体地，本发明提供了一种用于经验优化核酸探针的方法，通过用含有基因组不同区域中拷贝数变化的基因组DNA的样品进行测试。 本发明使得能够优化用于任何基于杂交的测定的探针，包括微阵列，基于珠的测定，基因分型测定和RNAi测定。

公开(公告)号：US20050223366A1

公开(公告)日：2005-10-06

申请号：US11092388

申请日：2005-03-29

Applicant: Steven Smith ,  Eric Schank ,  Brian Tyler

Inventor： Steven Smith ,  Eric Schank ,  Brian Tyler

IPC: G06F9/44

CPC classification number: G06F11/3495 ,  G06F11/3419 ,  G06F11/3433 ,  G06F11/3476 ,  G06F2201/86 ,  G06F2201/865 ,  G06F2201/87 ,  G06F2201/875 ,  G06F2201/88

Abstract: The disclosure is directed to an application server including memory including an instrumented computer executable application. The instrumented computer executable application includes a first application method including a first set of tracing instructions and first remote application access instructions. The first remote application access instructions include a transaction identification. The first remote application access instructions are configured to access a first remote application method located on a remote application server. The first remote application method is configured to access a second remote application method located on the remote application server. The instrumented computer executable application further includes a second application method including a first program segment including a second set of tracing instructions and instructions for accessing the first application method. The second application method further includes a second program segment including instructions configured to access the second remote application method.

Abstract translation: 本公开针对包括存储器的应用服务器，其包括仪表化的计算机可执行应用。 仪器化计算机可执行应用程序包括第一应用方法，其包括第一组跟踪指令和第一远程应用访问指令。 第一个远程应用程序访问指令包括事务标识。 第一个远程应用程序访问指令被配置为访问位于远程应用程序服务器上的第一个远程应用程序方法。 第一个远程应用程序方法被配置为访问位于远程应用程序服务器上的第二个远程应用程序方法。 仪器化计算机可执行应用还包括第二应用方法，其包括第一程序段，其包括第二组跟踪指令和用于访问第一应用方法的指令。 第二应用方法还包括包括被配置为访问第二远程应用方法的指令的第二程序段。

公开(公告)号：US20050185252A1

公开(公告)日：2005-08-25

申请号：US11118854

申请日：2005-04-28

Applicant: Bradley Haskett ,  John O'Connor ,  Steven Smith ,  Mark Miller ,  Ivan Kmecko ,  Jwei Liu ,  Edward Fisher ,  Frank Armstrong ,  Daniel Estabrook ,  Jeffrey Faris

Inventor： Bradley Haskett ,  John O'Connor ,  Steven Smith ,  Mark Miller ,  Ivan Kmecko ,  Jwei Liu ,  Edward Fisher ,  Frank Armstrong ,  Daniel Estabrook ,  Jeffrey Faris

IPC: G02B26/08 ,  G02B26/00

CPC classification number: G02B26/0841 ,  H01L2224/48091 ,  H01L2224/49175 ,  H01L2924/00014

Abstract: An improved window frame and window piece for a micromirror assembly is disclosed herein. The window frame includes a stress-relieving contour positioned in the middle of the frame that can absorb the mechanical stresses applied to the window frame from the ceramic base and from the window piece. The window frame may be comprised of a single piece of sheet metal that has been stamped to include a stress-relieving contour. The stress-relieving contour may be comprised of a variety of shapes, including a “U” shape, an inverted “U” shape, a curved step shape, or other combinations thereof.

Abstract translation: 本文公开了一种用于微镜组件的改进的窗框和窗件。 窗框包括位于框架中间的应力消除轮廓，其可以吸收从陶瓷基座和窗件施加到窗框的机械应力。 窗框可以由已经冲压以包括应力释放轮廓的单片金属片构成。 应力消除轮廓可以包括各种形状，包括“U”形，倒置的“U”形，弯曲的台阶形状或其它组合。

公开(公告)号：US20050157291A1

公开(公告)日：2005-07-21

申请号：US10943709

申请日：2004-09-17

Applicant: Carlos Bustamante ,  Steven Smith

Inventor： Carlos Bustamante ,  Steven Smith

IPC: G01B11/26 ,  G01N21/00 ,  G02B20060101

CPC classification number: G02B21/32 ,  G02B6/3578 ,  G02B27/62

Abstract: An alignment device and method for delivering a light beam to an optical application, such as an optical trap having a pair of lenses with overlapping focal regions for trapping a particle therein. The alignment device includes a light source for generating a beam of light, a support member, an optical fiber, a collimating lens, and actuators. The optical fiber includes an input end for receiving the beam of light, and a generally rigid portion extending from the support member and terminating in a delivery end for emitting the beam of light. The collimating lens collimates the emitted beam of light. The actuators exert forces on the generally rigid portion such that it pivots about a pivot point of the optical fiber at the support member. The collimated beam of light pivots about an optical pivot point as the optical fiber pivots about the pivot point.

Abstract translation: 一种用于将光束传送到光学应用的对准装置和方法，例如具有一对具有重叠聚焦区域的透镜的光阱，用于在其中捕获颗粒。 对准装置包括用于产生光束的光源，支撑构件，光纤，准直透镜和致动器。 光纤包括用于接收光束的输入端和从支撑构件延伸并终止于发射光束的输送端的大致刚性部分。 准直透镜准直发射的光束。 致动器在大致刚性部分上施加力，使得其在支撑构件处围绕光纤的枢转点枢转。 当光纤围绕枢转点枢转时，准直的光束绕光学枢轴点枢转。

公开(公告)号：US06745598B2

公开(公告)日：2004-06-08

申请号：US10264868

申请日：2002-10-04

Applicant: Simon Challis ,  Anura Fernando ,  Tilak Dias ,  William Cooke ,  Najmal Hassan Chaudhury ,  John Geraghty ,  Steven Smith

Inventor： Simon Challis ,  Anura Fernando ,  Tilak Dias ,  William Cooke ,  Najmal Hassan Chaudhury ,  John Geraghty ,  Steven Smith

IPC: D04B1548

CPC classification number: D04B15/56 ,  B65H51/205 ,  B65H2701/31 ,  D04B15/482

Abstract: A precision yarn (14) delivery system for the delivery of yarn from a yarn supply to a yarn utilising point, comprising a temporary yarn store (22) intermediate the supply and the utilisation point in which the yarn (14) is held under low tension and is fed from the store as required by the utilisation point.

Abstract translation: 一种用于将纱线从纱线供给到纱线利用点的精密纱线（14）输送系统，包括在纱线（14）在低张力下保持的供给和利用点之间的临时纱线存储器（22） 并根据利用点的要求从商店进货。

公开(公告)号：USD442773S1

公开(公告)日：2001-05-29

申请号：US29133620

申请日：2000-12-04

Applicant: Steven Smith

Designer： Steven Smith

公开(公告)号：USD440035S1

公开(公告)日：2001-04-10

申请号：US29131791

申请日：2000-10-27

Applicant: Steven Smith

Designer： Steven Smith

公开(公告)号：US06177012B1

公开(公告)日：2001-01-23

申请号：US09291053

申请日：1999-04-14

Applicant: David Lawler ,  Steven Smith

Inventor： David Lawler ,  Steven Smith

IPC: C02F334

CPC classification number: C12R1/07 ,  A23K10/16 ,  A23K20/189 ,  A23K30/18 ,  C02F3/342 ,  C12R1/125 ,  C12Y301/01003 ,  Y10S426/807 ,  Y10S435/821 ,  Y10S435/832

Abstract: This invention presents a newly discovered, novel strain of Bacillus bacteria that produces lipase enzymes for the degradation of oleaginous materials such as fats, greases and cooking oils, protease enzymes to degrade proteins and amylases to break down starch. This novel strain and the enzymes produced thereby have a number of applications, including wastewater treatments, agricultural uses, laundry and dish detergents, drain cleaners and spot removers, among others.

Abstract translation: 本发明提出了一种新发现的新型芽孢杆菌菌株，其产生用于降解含油物质如脂肪，油脂和食用油的蛋白酶，降解蛋白质和淀粉酶以分解淀粉的脂肪酶。 这种新型菌株和由此产生的酶具有许多应用，包括废水处理，农业用途，洗衣和洗涤剂，排水清洁剂和除斑剂等。

公开(公告)号：US06171847B2

公开(公告)日：2001-01-09

申请号：US09291055

申请日：1999-04-14

Applicant: David Lawler ,  Steven Smith

Inventor： David Lawler ,  Steven Smith

IPC: A23K110

CPC classification number: C12N9/2417 ,  A01N63/00 ,  A01N63/02 ,  A23K20/189 ,  C02F3/34 ,  C02F3/342 ,  C11D3/381 ,  C11D3/38627 ,  C12N9/20 ,  C12N9/54 ,  C12R1/125 ,  Y10S426/807 ,  Y10S435/832

Abstract: This invention presents a newly discovered, novel strain of Bacillus bacteria that produces lipase enzymes for the degradation of oleaginous materials such as fats, greases and cooking oils, protease enzymes to degrade proteins and amylases to break down starch. This novel strain and the enzymes produced thereby have a number of applications, including wastewater treatments, agricultural uses, laundry and dish detergents, drain cleaners and spot removers, among others.

Abstract translation: 本发明提出了一种新发现的新型芽孢杆菌菌株，其产生用于降解含油物质如脂肪，油脂和食用油的蛋白酶，降解蛋白质和淀粉酶以分解淀粉的脂肪酶。 这种新型菌株和由此产生的酶具有许多应用，包括废水处理，农业用途，洗衣和洗涤剂，排水清洁剂和除斑剂等。

公开(公告)号：US6162634A

公开(公告)日：2000-12-19

申请号：US291059

申请日：1999-04-14

Applicant: David Lawler ,  Steven Smith

Inventor： David Lawler ,  Steven Smith

IPC: A23K1/00 ,  A23K1/165 ,  A23K3/03 ,  A23L1/03 ,  C02F3/34 ,  C11D3/38 ,  C11D3/386 ,  B09B3/00 ,  C02F3/00 ,  C12N1/00 ,  C12N1/20

CPC classification number: C12R1/125 ,  A23K10/16 ,  A23K20/189 ,  A23K30/18 ,  A23L29/065 ,  C02F3/342 ,  C11D3/381 ,  C11D3/38627 ,  Y10S435/832 ,  Y10S435/839

Abstract: This invention presents a newly discovered, novel strain of Bacillus bacteria that produces lipase enzymes for the degradation of oleaginous materials such as fats, greases and cooking oils, protease enzymes to degrade proteins and amylases to break down starch. This novel strain and the enzymes produced thereby have a number of applications, including wastewater treatments, agricultural uses, laundry and dish detergents, drain cleaners and spot removers, among others.

Abstract translation: 本发明提出了一种新发现的新型芽孢杆菌菌株，其产生用于降解含油物质如脂肪，油脂和食用油的蛋白酶，降解蛋白质和淀粉酶以分解淀粉的脂肪酶。 这种新型菌株和由此产生的酶具有许多应用，包括废水处理，农业用途，洗衣和洗涤剂，排水清洁剂和除斑剂等。