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公开(公告)号:US20090123519A1
公开(公告)日:2009-05-14
申请号:US12291622
申请日:2008-11-12
CPC分类号: A61K9/1641 , A61K9/2031 , A61K47/00 , A61L27/26 , A61L27/50 , A61L27/52
摘要: The invention provides biocompatible polymeric hydrogel matrices having excellent durability and swellability. The matrices are formed from a macromer and photo-polymer combination. The matrices can be used in association with a medical device or alone. In some methods the polymeric matrix is placed or formed at a target site in which the matrix swells and occludes the target area.
摘要翻译: 本发明提供具有优异耐久性和溶胀性的生物相容性聚合物水凝胶基质。 基质由大分子单体和光聚合物组合形成。 矩阵可以与医疗装置或单独使用。 在一些方法中,聚合物基质被放置或形成在其中基质膨胀并封闭目标区域的靶位点。
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公开(公告)号:US6007833A
公开(公告)日:1999-12-28
申请号:US121248
申请日:1998-07-23
IPC分类号: A61K9/00 , A61K9/16 , A61K9/50 , A61K35/12 , A61K38/00 , A61K38/18 , A61K38/42 , A61K38/44 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/42 , A61L24/00 , A61L24/04 , A61L27/00 , A61L27/34 , A61L29/00 , A61L29/08 , A61L31/00 , A61L31/14 , C08B37/08 , C08F251/00 , C08F251/02 , C08F290/00 , C08L51/02 , A61K47/30 , C08J3/28 , C08J7/18 , C12N11/08
CPC分类号: C08B37/0072 , A61K38/1875 , A61K9/1641 , A61K9/1647 , A61L24/0031 , A61L24/0042 , A61L24/046 , A61L27/34 , A61L29/085 , A61L31/148 , C08F251/00 , C08F251/02 , C08F290/00 , C08L51/02 , A61K2035/128 , A61K47/32 , A61K47/34 , A61K9/0024 , Y10S522/904 , Y10S522/905
摘要: A crosslinkable macromer system that includes two or more polymer-pendent polymerizable groups and one or more polymer-pendent initiator groups. The polymerizable groups and the initiator group(s) can be pendent on the same or different polymeric backbones. The macromer system provides advantages over the use of polymerizable macromers and separate, low molecular weight initiators, including advantages with respect to such properties as nontoxicity, efficiency, and solubility.
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