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公开(公告)号：US20050282214A1
公开(公告)日：2005-12-22
申请号：US11183914
申请日：2005-07-19
申请人： Olga Bandman , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Y. Tang , Purvi Shah
发明人： Olga Bandman , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Y. Tang , Purvi Shah
CPC分类号： C12N9/6424 , A61K38/00 , C07K16/40 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要： The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
摘要翻译： 本发明提供了人类蛋白酶分子（HUPM）和识别和编码HUPM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与HUPM表达相关的病症的方法。
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公开(公告)号：US20050256036A1
公开(公告)日：2005-11-17
申请号：US11046644
申请日：2005-01-27
申请人： Bryan Boyle , Walter Funk , Makoto Kakitani , Takeshi Oshima , Eun Park , Y. Tang , Mikio Yagi , Kazuma Tomizuka
发明人： Bryan Boyle , Walter Funk , Makoto Kakitani , Takeshi Oshima , Eun Park , Y. Tang , Mikio Yagi , Kazuma Tomizuka
IPC分类号： A01K67/027 , A61K38/18 , A61K48/00 , C07K14/475 , C12N15/85 , G01N33/50
CPC分类号： G01N33/5088 , A01K67/0275 , A01K2217/072 , A01K2227/105 , A01K2267/01 , A61K38/1709 , A61K48/005 , C07K14/475 , C12N15/8509 , C12N2799/022 , C12N2800/30
摘要： The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor (GIPF) polynucleotides and polypeptides. The invention further relates to the therapeutic use of GIPF to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
摘要翻译： 本发明涉及包含胃肠增生因子（GIPF）多核苷酸和多肽的药物组合物。 本发明还涉及GIPF用于预防或治疗与上皮粘膜变性相关的病症或病症的治疗用途。
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公开(公告)号：US20050239126A1
公开(公告)日：2005-10-27
申请号：US11167040
申请日：2005-06-27
申请人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
发明人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
摘要翻译： 本发明提供鉴定和编码PRTS的人类蛋白酶（PRTS）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与PRTS异常表达相关的疾病的方法。
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公开(公告)号：US20050214795A1
公开(公告)日：2005-09-29
申请号：US10974440
申请日：2004-10-26
申请人： Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
发明人： Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12P21/08 , C12Q1/68 , C07H21/04 , C12N9/22
CPC分类号： C07K14/4702 , A61K38/00
摘要： The invention provides human transcriptional regulator molecules (HTRM) and polynucleotides which identify and encode HTRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HTRM.
摘要翻译： 本发明提供了人转录调节分子（HTRM）和识别和编码HTRM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与HTRM表达相关的障碍的方法。
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公开(公告)号：US20050202474A1
公开(公告)日：2005-09-15
申请号：US11038257
申请日：2005-01-21
申请人： Mariah Baughn , Dyung Lu , Henry Yue , Y. Tang , Danniel Nguyen
发明人： Mariah Baughn , Dyung Lu , Henry Yue , Y. Tang , Danniel Nguyen
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P27/02 , A61P29/00 , A61P35/00 , A61P37/06 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/16 , C12N15/09 , C12Q1/02 , C12Q1/44 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C12N9/16 , A01K2217/05 , A61K38/00 , A61K48/00
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
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公开(公告)号：US20050186569A1
公开(公告)日：2005-08-25
申请号：US10491472
申请日：2002-10-29
申请人： Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
发明人： Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
CPC分类号： C07K14/4702 , C07K14/47
摘要： A Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050181415A1
公开(公告)日：2005-08-18
申请号：US11079743
申请日：2005-03-14
申请人： Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
发明人： Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
IPC分类号： A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , G01N33/68 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N15/85
CPC分类号： C12Y101/01001 , A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , C12Y205/01018 , G01N33/6893 , G01N2500/00
摘要： The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.
摘要翻译： 本发明提供了人类代谢酶（DME）和识别和编码DME的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与DME的异常表达相关的紊乱的方法。
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公开(公告)号：US20050181404A1
公开(公告)日：2005-08-18
申请号：US11045577
申请日：2005-01-27
申请人： Olga Bandman , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Y. Tang , Purvi Shah
发明人： Olga Bandman , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Y. Tang , Purvi Shah
CPC分类号： C12N9/6424 , A61K38/00 , C07K16/40 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要： The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
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公开(公告)号：US20050142600A1
公开(公告)日：2005-06-30
申请号：US11046868
申请日：2005-02-01
申请人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
发明人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
CPC分类号： C12N9/6421 , A01K2217/05 , A61K38/00 , C07H21/04 , C12N9/64
摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
摘要翻译： 本发明提供了鉴定和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与PMMM的异常表达相关的紊乱的方法。
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公开(公告)号：US20050130204A1
公开(公告)日：2005-06-16
申请号：US10986822
申请日：2004-11-15
申请人： Y. Tang , Preeti Lal , Olga Bandman , Henry Yue , Neil Corley , Karl Guegler , Gina Gorgone , Mariah Baughn , Chandra Patterson
发明人： Y. Tang , Preeti Lal , Olga Bandman , Henry Yue , Neil Corley , Karl Guegler , Gina Gorgone , Mariah Baughn , Chandra Patterson
IPC分类号： A61K38/00 , C07K14/47 , C12Q1/68 , C07H21/04 , C07K14/705
摘要： The invention provides human protein transport molecules (PTAM) and polynucleotides which identify and encode PTAM. The Invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of PTAM.
摘要翻译： 本发明提供鉴定和编码PTAM的人蛋白转运分子（PTAM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PTAM表达相关的障碍的方法。
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