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    Targetry coupled separations
    52.
    发明申请
    Targetry coupled separations 审中-公开
    Targetry加分离

    公开(公告)号：US20160189816A1

    公开(公告)日：2016-06-30

    申请号：US14757683

    申请日：2015-12-23

    申请人： TerraPower, LLC

    发明人： Ken Czerwinski ,  Joshua C. Walter

    IPC分类号： G21G1/02 ,  G21G1/06

    CPC分类号： G21G1/02 ,  B01D11/0203 ,  B01D11/0403 ,  B01D15/40 ,  B01D2215/027 ,  G21C19/42 ,  G21G1/08 ,  G21G2001/0036 ,  Y02P20/544

    摘要： Targetry coupled separation refers to enhancing the production of a predetermined radiation product through the selection of a target (including selection of the target material and the material's physical structure) and separation chemistry in order to optimize the recovery of the predetermined radiation product. This disclosure describes systems and methods for creating (through irradiation) and removing one or more desired radioisotopes from a target and further describes systems and methods that allow the same target to undergo multiple irradiations and separation operations without damage to the target. In contrast with the prior art that requires complete dissolution or destruction of a target before recovery of any irradiation products, the repeated reuse of the same physical target allowed by targetry coupled separation represents a significant increase in efficiency and decrease in cost over the prior art.

    摘要翻译： 靶向偶联分离是指通过选择靶标（包括靶材料和材料的物理结构的选择）和分离化学物质来增强预定辐射产物的生产，以优化预定辐射产物的回收。 本公开描述了用于创建（通过照射）并从目标去除一个或多个所需放射性同位素的系统和方法，并且进一步描述允许相同目标经受多次照射和分离操作而不损害目标的系统和方法。 与在回收任何辐射产物之前需要完全溶解或破坏靶的现有技术相反，与目标物耦合分离所允许的相同物理目标的重复再利用代表了现有技术中效率的显着增加和成本的降低。

    Methods for recovering organic heteroatom compounds from hydrocarbon feedstocks
    55.
    发明授权
    Methods for recovering organic heteroatom compounds from hydrocarbon feedstocks 有权
    从烃原料中回收有机杂原子化合物的方法

    公开(公告)号：US08961780B1

    公开(公告)日：2015-02-24

    申请号：US14107471

    申请日：2013-12-16

    申请人： Saudi Arabian Oil Company

    发明人： Zaki Yusuf ,  Ahmad D. Hammad ,  Stamatios Souentie ,  Bandar Fadhel ,  Nayif Rasheedi

    IPC分类号： C10G21/12 ,  C07C7/10

    CPC分类号： C10G21/28 ,  B01D11/0403 ,  B01J3/008 ,  C07C7/10 ,  C07D207/00 ,  C10G21/08 ,  C10G2300/202 ,  C10G2300/205 ,  C10G2300/44

    摘要： Methods for recovering organic heteroatom compounds from a hydrocarbon feedstock include feeding into a contactor a hydrocarbon feedstock and an aqueous solvent to form an extraction mixture of the aqueous solvent with the hydrocarbon feedstock. The hydrocarbon feedstock includes a hydrocarbon and an organic heteroatom compound. The aqueous solvent includes an ionic liquid formed from pressurized carbon dioxide and water. A pressure and temperature of the extraction mixture may be established that together tune the aqueous solvent to selectively form a solvent complex with the at least one organic heteroatom compound. Then, the solvent complex is extracted to a recovery vessel from the extraction mixture in the contactor. By adjustment of a recovery temperature of the recovery vessel, a recovery pressure of the recovery vessel, or both, the solvent complex decomposes into carbon dioxide and the organic heteroatom compound. The organic heteroatom compound is then recovered from the recovery vessel.

    摘要翻译： 从烃原料中回收有机杂原子化合物的方法包括将烃原料和含水溶剂进料到接触器中以形成含水溶剂与烃原料的萃取混合物。 烃原料包括烃和有机杂原子化合物。 含水溶剂包括由加压二氧化碳和水形成的离子液体。 可以建立萃取混合物的压力和温度，其一起调节水性溶剂以选择性地与至少一种有机杂原子化合物形成溶剂配合物。 然后，将溶剂配合物从接触器中的萃取混合物中提取回收容器。 通过调节回收容器的回收温度，回收容器的回收压力或二者，溶剂配合物分解成二氧化碳和有机杂原子化合物。 然后从回收容器中回收有机杂原子化合物。

    Method For Producing Solid-Lipid Composite Drug Particles
    57.
    发明申请
    Method For Producing Solid-Lipid Composite Drug Particles 有权
    生产固体脂质复合药物颗粒的方法

    公开(公告)号：US20080286365A1

    公开(公告)日：2008-11-20

    申请号：US12124518

    申请日：2008-05-21

    申请人： Boris Y. Shekunov ,  Pratibhash Chattopadhyay ,  Robert W. Huff

    发明人： Boris Y. Shekunov ,  Pratibhash Chattopadhyay ,  Robert W. Huff

    IPC分类号： A61K9/14 ,  A61K47/00 ,  A61P43/00

    CPC分类号： A61K9/167 ,  A61K9/5123 ,  B01D11/0403 ,  B01D11/0407 ,  B01D11/0411 ,  B01D11/0484 ,  B01J13/02

    摘要： A method of producing solid composite lipid/drug nanoparticles that includes the steps of: (1) dissolving a lipid and a drug in a suitable organic solvent to form a solution; (2) emulsifying the solution in a liquid to form an emulsion having a discontinuous phase of micelles comprising the organic solvent, the drug and the lipid, and a continuous phase comprising the liquid; and (3) contacting the emulsion with a supercritical fluid under conditions suitable to keep the supercritical fluid in a supercritical state, whereby the supercritical fluid extracts the organic solvent from the micelles, causing them to precipitate as organic-solvent free solid composite lipid/drug nanoparticles suspended or dispersed in the liquid.

    摘要翻译： 一种生产固体复合脂质/药物纳米颗粒的方法，其包括以下步骤：（1）将脂质和药物溶解在合适的有机溶剂中以形成溶液; （2）将溶液乳化在液体中以形成具有包含有机溶剂，药物和脂质的胶束不连续相的乳液和包含液体的连续相; 和（3）在适合于使超临界流体处于超临界状态的条件下使乳液与超临界流体接触，由此超临界流体从胶束中提取有机溶剂，导致它们作为无机溶剂固体复合脂质/药物沉淀 悬浮或分散在液体中的纳米颗粒。

    Method and device for the extraction of substances from liquids or solids dispersions
    59.
    发明申请
    Method and device for the extraction of substances from liquids or solids dispersions 失效
    从液体或固体分散体中提取物质的方法和装置

    公开(公告)号：US20060000781A1

    公开(公告)日：2006-01-05

    申请号：US10526003

    申请日：2003-08-26

    申请人： Helmut Seidlitz ,  Eduard Lack

    发明人： Helmut Seidlitz ,  Eduard Lack

    IPC分类号： B01D11/00

    CPC分类号： B01D11/0407 ,  B01D11/0403 ,  B01D11/048

    摘要： In a method for extracting ingredients, particularly foreign substances, from liquids or solids dispersions by using compressed extraction agents such as, for instance, supercritical or liquid carbon dioxide, the liquid or dispersion is applied as a thin film in a pressure-tight reactor and the surface of the thin film is treated with the extraction agent, particularly carbon dioxide, wherein the surface of the thin film is constantly renewed over at least a portion of the layer thickness of the thin film by mechanically acting on said liquid or dispersion.

    摘要翻译： 在通过使用例如超临界或液体二氧化碳的压缩萃取剂从液体或固体分散体中提取成分，特别是异物的方法中，将液体或分散体作为薄膜施加在耐压反应器中， 用提取剂，特别是二氧化碳处理薄膜的表面，其中薄膜的表面通过机械作用在所述液体或分散体上而在薄膜的层厚度的至少一部分上不断更新。

    Particle formation
    60.
    发明申请
    Particle formation 审中-公开
    颗粒形成

    公开(公告)号：US20050085409A1

    公开(公告)日：2005-04-21

    申请号：US10753757

    申请日：2004-01-07

    申请人： Andreas Kordikowski ,  Darren Gilbert

    发明人： Andreas Kordikowski ,  Darren Gilbert

    IPC分类号： B01D11/04 ,  B01J2/04 ,  A61K38/00 ,  B29B9/00

    CPC分类号： B01J2/04 ,  B01D11/0403 ,  B01D11/0407 ,  B01D11/0411 ,  B01D11/0473 ,  B01D11/0484

    摘要： Method for preparing a target substance in particulate form, by introducing into a particle formation vessel, through separate first and second fluid inlets respectively, (a) a solution or suspension of the target substance in a fluid vehicle (the “target solution/suspension”) and (b) a compressed fluid anti-solvent for the substance, and allowing the anti-solvent to extract the vehicle from the target solution/suspension so as to form particles of the target substance, wherein the target solution/suspension enters the vessel downstream of the point of entry of the anti-solvent and at a point which lies on or close to the main axis of anti-solvent flow, and wherein the anti-solvent has a sub-sonic velocity as it enters the particle formation vessel.

    摘要翻译： 通过分别通过分开的第一和第二流体入口引入颗粒形成容器，（a）目标物质在流体载体中的溶液或悬浮液（“目标溶液/悬浮液”）的制备方法， ）和（b）用于该物质的压缩流体抗溶剂，并且允许反溶剂从目标溶液/悬浮液中提取载体以形成目标物质的颗粒，其中目标溶液/悬浮液进入容器 在反溶剂进入点的下游，位于或接近反溶剂流动主轴线的点处，并且其中反溶剂在其进入颗粒形成容器时具有次声速度。