公开(公告)号：US08357652B2

公开(公告)日：2013-01-22

申请号：US12623162

申请日：2009-11-20

Applicant: Shu-Mei Liang ,  Chi-Ming Liang

Inventor： Shu-Mei Liang ,  Chi-Ming Liang

IPC: A61K35/12 ,  A61K38/00

CPC classification number: A61K38/385 ,  A61K38/162 ,  A61K38/38 ,  A61K45/06 ,  A61K47/643 ,  A61N5/10 ,  C07K14/765 ,  C12N7/00 ,  C12N2770/32133

Abstract: Fibrillar human serum albumin was shown to be effective in the treatment of various types of cancers. Methods and compositions are disclosed for using fibrillar human serum albumin as a medicament to treat subjects having cancer.

Abstract translation: 纤维素人血清白蛋白显示有效治疗各种类型的癌症。 公开了使用原纤维人血清白蛋白作为治疗患有癌症的受试者的药物的方法和组合物。

公开(公告)号：US08354234B2

公开(公告)日：2013-01-15

申请号：US11487823

申请日：2006-07-17

Applicant: Yu-Ju Chen ,  Po-Chiao Lin ,  Chun-Cheng Lin ,  Shu-Hua Chen ,  Po-Hung Chou ,  Hsin-Kai Liao

Inventor： Yu-Ju Chen ,  Po-Chiao Lin ,  Chun-Cheng Lin ,  Shu-Hua Chen ,  Po-Hung Chou ,  Hsin-Kai Liao

IPC: G01N33/53 ,  G01N33/543 ,  G01N33/553

CPC classification number: B82Y15/00 ,  B82Y30/00 ,  G01N33/54333 ,  G01N33/6851

Abstract: The present invention provides methods, compositions, and systems for mass spectrometric analysis of magnetic nanoparticles displaying ligands on their surface. For example, the present invention provides methods of screening a sample for the presence of at least one analyte using ligand conjugated magnetic nanoparticles, magnetic separation, and mass spectrometric analysis. The present invention also relates to MALDI matrix compositions comprising ligand conjugated magnetic nanoparticles.

Abstract translation: 本发明提供了在其表面上显示配体的磁性纳米颗粒的质谱分析的方法，组合物和系统。 例如，本发明提供了使用配体共轭磁性纳米颗粒筛选样品以存在至少一种分析物的方法，磁分离和质谱分析。 本发明还涉及包含配体缀合的磁性纳米颗粒的MALDI基质组合物。

公开(公告)号：US08354127B2

公开(公告)日：2013-01-15

申请号：US12378263

申请日：2009-02-12

Applicant: Chi-Huey Wong ,  Wen-Bin Yang ,  Ting-Jen Cheng ,  Yves Shang-Yi Hsieh ,  Cheng Chien ,  Chih-Chien Lin ,  Hao-Yu Wen ,  Jim-Min Fang

Inventor： Chi-Huey Wong ,  Wen-Bin Yang ,  Ting-Jen Cheng ,  Yves Shang-Yi Hsieh ,  Cheng Chien ,  Chih-Chien Lin ,  Hao-Yu Wen ,  Jim-Min Fang

IPC: A61K36/00 ,  A61K31/715

CPC classification number: A61K36/8984

Abstract: Compositions and methods are disclosed relating to use of fractions, polysaccharides, and oligosaccharides of Dendrobium huoshanense. The fractions, polysaccharides, and oligosaccharides are able to effect an increase in beneficial cytokines and chemokines.

公开(公告)号：US20130001415A1

公开(公告)日：2013-01-03

申请号：US13534449

申请日：2012-06-27

Applicant: Chung-Hsuan CHEN ,  I-Chung LU ,  Ming-Lee CHU

Inventor： Chung-Hsuan CHEN ,  I-Chung LU ,  Ming-Lee CHU

IPC: H01J49/36 ,  H01J49/04 ,  H01J49/18 ,  H01J49/16 ,  H01J49/14

CPC classification number: H01J49/4225 ,  H01J49/429

Abstract: An ion trap mass spectrometer and methods for obtaining a mass spectrum of ions by scanning an RF frequency applied to the linear ion trap for mass selective ejection of the ions by using two power amplifiers to apply opposite phases of the RF to x and y electrodes.

Abstract translation: 一种离子阱质谱仪和通过扫描施加到线性离子阱的RF频率来获得离子的质谱的方法，用于通过使用两个功率放大器将RF的相反相施加到x和y电极来质量选择性地喷射离子。

公开(公告)号：US20130001089A1

公开(公告)日：2013-01-03

申请号：US13170624

申请日：2011-06-28

Applicant: Lain-Jong Li ,  Ching-Yuan Su

Inventor： Lain-Jong Li ,  Ching-Yuan Su

IPC: C25D9/04 ,  C25D5/50 ,  C25D5/48 ,  C25D7/00 ,  B82Y40/00 ,  B82Y99/00

CPC classification number: B82Y30/00 ,  B82Y40/00 ,  C01B32/19 ,  C01B2204/32 ,  C25B1/00 ,  Y10S977/845

Abstract: A method of preparing graphene sheets. The method includes: immersing a portion of a first electrode and a portion of a second electrode in a solution containing an acid, an anionic surfactant, a salt, an oxidizing agent, or any combination thereof as an electrolyte, the immersed portion of the first electrode including a first carbon material and the immersed portion of the second electrode including a second carbon material or a metal; causing a potential to exist between the first and second electrodes; and recovering, from the solution, graphene sheets exfoliated from the carbon material(s). Also disclosed is a method of preparing a graphene film electrode. The method includes: dissolving graphene sheets in an organic solvent to form a solution, applying the solution on a substrate, adding deionized water to the solution on the substrate so that a graphene film is formed, and drying the graphene film.

Abstract translation: 制备石墨烯片的方法。 该方法包括：将第一电极和第二电极的一部分浸入含有酸，阴离子表面活性剂，盐，氧化剂或其任何组合的溶液中作为电解质，第一 包括第一碳材料的电极和包括第二碳材料或金属的第二电极的浸没部分; 导致在第一和第二电极之间存在潜力; 并从溶液中回收从碳材料剥离的石墨烯片。 还公开了制备石墨烯膜电极的方法。 该方法包括：将石墨烯片溶解在有机溶剂中以形成溶液，将溶液涂布在基材上，向基板上的溶液中加入去离子水，形成石墨烯膜，并干燥石墨烯膜。

公开(公告)号：US20120328646A1

公开(公告)日：2012-12-27

申请号：US13568510

申请日：2012-08-07

Applicant: Chi-Huey Wong ,  Chung-Yi Wu ,  Alice L. Yu ,  John Yu

Inventor： Chi-Huey Wong ,  Chung-Yi Wu ,  Alice L. Yu ,  John Yu

IPC: A61K39/385 ,  A61P35/00 ,  C07K14/33 ,  C07K14/00 ,  C07K14/34

CPC classification number: A61K39/0011 ,  A61K2039/55511 ,  A61K2039/6037 ,  A61K2039/6081 ,  A61K2039/627 ,  C12N15/1137 ,  C12N2310/14

Abstract: An immunogenic composition containing a glycan conjugate including a carrier protein, and a glycan including Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4 (SSEA-4), wherein the glycan is conjugated with the carrier protein through a linker.

Abstract translation: 含有载体蛋白的聚糖缀合物和包含Globo H，其免疫原性片段或阶段特异性胚胎抗原-4（SSEA-4）的聚糖的免疫原性组合物，其中所述聚糖通过接头与载体蛋白质缀合 。

公开(公告)号：US08329413B2

公开(公告)日：2012-12-11

申请号：US13053192

申请日：2011-03-21

Applicant: Chi-Huey Wong ,  Tsui-Ling Hsu ,  Sarah R Hanson ,  Masaaki Sawa

Inventor： Chi-Huey Wong ,  Tsui-Ling Hsu ,  Sarah R Hanson ,  Masaaki Sawa

IPC: G01N33/53

CPC classification number: G01N33/582 ,  G01N1/30 ,  G01N2400/00

Abstract: Methods are provided for labeling cellular glycans bearing azide groups via fluorescent labeling comprising Cu(I)-catalyzed [3+2] cycloaddition of a probe comprising alkynyl group. Generation of fluorescent probes from a nonfluorescent precursor, 4-ethynyl-N-ethyl-1,8-naphthalimide, by Cu(I)-catalyzed [3+2] cycloaddition of the alkyne group of the probe to an azido-modified sugar are provided. Incorporation of azido-containing fucose analog into glycoconjugates via the fucose salvage pathway are disclosed. Fluorescent visualization of fucosylated cells by flow cytometry of cells treated with 6-azidofucose labeled with click-activated fluorogenic probe or biotinylated alkyne is disclosed. Visualization of intracellular location of fucosylated glycoconjugates by fluorescence microscopy are disclosed.

Abstract translation: 提供了通过含有包含炔基的探针的Cu（I）催化的[3 + 2]环加成的荧光标记来标记携带叠氮基的细胞聚糖的方法。 通过Cu（I）催化的[3 + 2]环加成的探针的炔基与叠氮改性的糖，从非荧光前体4-乙炔基-N-乙基-1,8-萘二甲酰亚胺生成荧光探针是 提供。 公开了通过岩藻糖补救途径将叠氮基岩藻糖类似物掺入糖缀合物。 公开了通过用用点击激活的荧光探针或生物素化的炔标记的6-叠氮基聚糖处理的细胞的流式细胞术的岩藻糖基化细胞的荧光可视化。 公开了通过荧光显微镜观察岩藻糖基化糖缀合物的细胞内位置。

公开(公告)号：US20120297218A1

公开(公告)日：2012-11-22

申请号：US13468209

申请日：2012-05-10

Applicant: Pi-Cheng Hsiu ,  Chun-Han Lin ,  Cheng-Kang Hsieh

Inventor： Pi-Cheng Hsiu ,  Chun-Han Lin ,  Cheng-Kang Hsieh

IPC: G06F1/32 ,  G09G5/10

CPC classification number: G06F1/3265 ,  G09G3/3406 ,  G09G2330/021 ,  Y02D10/153

Abstract: A cloud-based energy-saving service system and method are disclosed. The service system and method of this invention use the strong computation capabilities of the cloud computing technology and systems to determine the power consumption policies of the mobile devices and provide the policies to the mobile devices, whereby the mobile devices implement the power consumption policies to save its power consumptions. In one aspect, the invented system and method calculate and determine the backlight level polices for a particular video stream, then provide the policies information to the mobile devices for implementation. The policies information may be provided to the mobile devices independently or along with the video stream. The calculation of the backlight illumination levels may be done in advance or on remand.

Abstract translation: 公开了一种基于云的节能服务体系和方法。 本发明的服务系统和方法使用云计算技术和系统的强大的计算能力来确定移动设备的功耗策略，并向移动设备提供策略，由此移动设备实现功耗策略来保存 其功耗。 一方面，本发明的系统和方法计算并确定特定视频流的背光级别策略，然后向移动设备提供策略信息以供实现。 策略信息可以独立地或与视频流一起提供给移动设备。 背光照明水平的计算可以提前进行还是还原。

公开(公告)号：US20120287505A1

公开(公告)日：2012-11-15

申请号：US13468602

申请日：2012-05-10

Applicant: Yia-Chung Chang ,  Li-Chuan Tang

Inventor： Yia-Chung Chang ,  Li-Chuan Tang

IPC: G02B27/22

CPC classification number: G02B27/2214 ,  H04N13/302

Abstract: An auto-stereoscopic display and three-dimensional imaging double-sided mirror array being low-loss and nearly dispersion-less. The double-sided mirror array for auto-stereoscopic display and three-dimensional (3D) imaging comprises a display panel, a slab and an array. The display panel comprises multiple display pixels. The slab is in close contact with the display panel. The array comprises at least two vertical mirror strips, at least one vertical blinds and a spacing. Each vertical mirror strip is inserted into the slab. Each vertical blind is shorter than the vertical mirror strip and is inserted into the slab between two vertical mirror strips. The spacing is between the vertical mirror strip and the vertical blind and is chosen to match the width of the display pixels exactly.

Abstract translation: 自动立体显示和三维成像双面镜阵列是低损耗和几乎不分散的。 用于自动立体显示和三维（3D）成像的双面镜阵列包括显示面板，平板和阵列。 显示面板包括多个显示像素。 平板与显示面板紧密接触。 该阵列包括至少两个垂直镜条，至少一个垂直百叶窗和间隔。 每个垂直镜条被插入板中。 每个垂直盲板比垂直镜片条短，并且在两个垂直镜带之间插入板坯。 间隔在垂直镜片条和垂直百叶窗之间，并被选择为精确地匹配显示像素的宽度。

公开(公告)号：US08222297B2

公开(公告)日：2012-07-17

申请号：US12008512

申请日：2008-01-11

Applicant: Tsann-Long Su ,  Ting-Chao Chou

Inventor： Tsann-Long Su ,  Ting-Chao Chou

IPC: A61K31/17 ,  C07C275/40

CPC classification number: C07D219/10 ,  C07C275/42 ,  C07D215/233 ,  C07D215/42

Abstract: New aniline or phenol N-mustards linked to DNA-affinity carriers (such as 9-anilinoacridines, acridines and quinolines), aminobenzamides or aminophenol ethers by a urea, carbamic acid, carbanic acid ester, hydrazineurea, hydrazinecarbamic acid ester, phenoxyurea, phenoxycarbamic acid ester linkage with improved chemical stability and anti-tumor therapeutic efficacy are provided.

Abstract translation: 新的苯胺或苯酚N-氮芥与尿素，氨基甲酸，碳酸酯，肼脲，肼氨基甲酸酯，苯氧基脲，苯氧基氨基甲酸 提供了具有改善的化学稳定性和抗肿瘤治疗功效的酯连接。