A METHOD FOR DISTINGUISHING BETWEEN MORE THAN ONE FLUORESCENT SPECIES PRESENT IN A SAMPLE

    公开(公告)号:US20210334513A1

    公开(公告)日:2021-10-28

    申请号:US16322742

    申请日:2017-08-03

    Inventor: Antony Orth

    Abstract: Methods and systems are provided for distinguishing between more than one fluorescent species present in a sample in fluorescence microscopy. The method involves illuminating the sample with at least one light source. More than two images of the illuminated sample are recorded over a period of time, each image comprising a plurality of pixels, wherein each pixel corresponds to a location in the sample and records a degree of fluorescence at the location in the sample at a particular point in time. A photostability characteristic of the degree of fluorescence at each pixel over the period of time over which the more than two images were recorded is determined and used to distinguish between the more than one fluorescent species present in the sample.

    Memristor device and a method of fabrication thereof

    公开(公告)号:US10985318B2

    公开(公告)日:2021-04-20

    申请号:US15778776

    申请日:2016-11-23

    Abstract: A memristor device is disclosed comprising: a first electrode; a second electrode; a cathode metal layer disposed on a surface of the first electrode; and an active region disposed between and in electrical contact with the second electrode and the cathode metal layer, the active region comprising at least one layer of an amorphous metal oxide, wherein when a switching voltage is applied between the first and second electrodes, the active region exhibits a resistive switching behaviour. A method of fabricating a memristor device is also disclosed.

    MULTICORE FIBER IMAGING
    64.
    发明申请

    公开(公告)号:US20210048660A1

    公开(公告)日:2021-02-18

    申请号:US16965513

    申请日:2019-01-25

    Inventor: Antony ORTH

    Abstract: The invention relates to multicore fiber imaging, such as used in endoscopy. Methods are described for processing images captured with such systems to achieve an improved depth of field image or extract 3D information concerning the images, without requiring the addition of additional optical components. One method for generating an image from light received by an imager via a multiplicity of waveguides includes receiving a digital image containing a plurality of pixels, the digital image including a plurality of regions within it wherein each of said regions corresponds to a waveguide core. Each region includes a plurality of pixels, and a first subset of pixels within each region is defined which at least partly correlates with light having been received at a corresponding core in a first spatial arrangement, the subset including less than all of the pixels within a region. A first image is generated from the first subset of pixels from said regions, combined to form an image over the whole waveguide array. The first spatial arrangement may correspond to a measure of angular dimension of the incident light for that region. In addition to increased depth of field, the modified images provided by the invention allow 3D visualisation of objects, eg. using stereographs or depth mapping techniques.

    SENSOR ARRAY SYSTEM
    67.
    发明申请
    SENSOR ARRAY SYSTEM 审中-公开
    传感器阵列系统

    公开(公告)号:US20160166178A1

    公开(公告)日:2016-06-16

    申请号:US14903663

    申请日:2014-07-09

    Abstract: A sensor grid is provided which is able to provide signals of the magnitude and location on the grid of applied pressure. In the prime application of gait analysis, the sensor in the sole of a shoe provides over time a signal indicative of the magnitude and movement of the centre of pressure. This may be presented as a visual signal showing the location of the centre of pressure on the outline of the sole with pressure values coded in colour. Alternatively the location may be represented as pitch of an audio signal and the magnitude by sound volume. Such a signal can be used to provide feedback to a patient to correct their gait by modifying their gait to produce a desirable signal. The analysis software uses an algorithm to identify the location, speed and distribution of the centre of pressure (COP) and additionally to assess the fractal dimension of the COP. Other attributes such as location of hotspots and pressure impulses can be used to augment the biofeedback signals. The sensor system may be used in other sensing applications such as measuring impacts in sports or pressure points in patients confined to sitting or prone positions.

    Abstract translation: 提供传感器网格,其能够提供施加压力网格上的幅度和位置的信号。 在步态分析的主要应用中,鞋底中的传感器随时间提供指示压力中心的大小和运动的信号。 这可以作为视觉信号来表示,其中压力值以彩色编码,示出了鞋底轮廓上的压力中心的位置。 或者,位置可以表示为音频信号的音高和音量的大小。 这样的信号可以用于通过修改其步态以产生期望的信号来向患者提供反馈以校正其步态。 分析软件使用算法来识别压力中心(COP)的位置,速度和分布,另外评估COP的分形维数。 可以使用诸如热点位置和压力​​脉冲的其他属性来增加生物反馈信号。 传感器系统可用于其他感测应用,例如测量受限于坐姿或俯卧位的患者的运动或压力点的影响。

    Apparatus for addressing wells within a microarray plate

    公开(公告)号:US12275039B2

    公开(公告)日:2025-04-15

    申请号:US16771947

    申请日:2018-12-11

    Abstract: An apparatus, including at least one piezoelectric chip having a working surface, and an opposing at least substantially parallel transducer surface; and at least one interdigital transducer applied to the transducer surface of the chip for generating acoustic energy within the chip in response to an application of an electrical signal to the interdigital transducer; wherein the working surface of the chip is, when in use, in contact with a fluid receptacle to thereby acoustically actuate fluid accommodated within said fluid receptacle, the chip being directly in contact with the receptacle or in contact with a fluid coupling medium that is in contact with the receptacle.

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