3-Oxo-pregna-1,14,17-trien-20-carboxylates and process
    65.
    发明授权
    3-Oxo-pregna-1,14,17-trien-20-carboxylates and process 失效
    3-氧代 - 前 - 1,14,17-三烯-20-羧酸酯和方法

    公开(公告)号:US4333880A

    公开(公告)日:1982-06-08

    申请号:US228177

    申请日:1981-01-26

    IPC分类号: C12P33/16 C07J9/00 C07J13/00

    CPC分类号: C07J13/007 C07J9/005

    摘要: A .DELTA..sup.1,4,17 -BNC compound having the formula: ##STR1## wherein X is a substituent selected from the group consisting of OH and OCH.sub.3 ; as well as its process of production by microbiological side-chain splitting of a 17-C-side-chain steroid with a defect mutant microorganism which gives a steroid with a 17-C-.alpha.-propionic acid substituent in the absence of inhibitors inhibiting either the cleavage of the steroid ring or microorganism growth, where the defect mutant microorganisms are grown under a reduced air supply whereby an enrichment of .DELTA..sup.1,4,17 -BNC occurs.

    摘要翻译: 具有下式的DELTA 1,4,17-BNC化合物:其中X是选自OH和OCH 3的取代基; 以及其通过17-C-侧链类固醇与缺失突变体微生物的微生物侧链裂解的生产过程,所述缺陷突变体微生物在不存在抑制剂的情况下给予具有17-C-α-丙酸取代基的类固醇 类固醇环或微生物生长的切割,其中缺陷突变体微生物在减少的空气供应下生长,从而发生DELTA 1,4,17-BNC的富集。

    Process for the enzymatic softening of furs
    67.
    发明授权
    Process for the enzymatic softening of furs 失效
    毛皮酶促软化的过程

    公开(公告)号:US4260686A

    公开(公告)日:1981-04-07

    申请号:US67512

    申请日:1979-08-17

    IPC分类号: C14C1/00

    CPC分类号: C14C1/00

    摘要: The present invention concerns a process for the softening of furs while at the same time taking the greatest possible care of the appearance of the hair. The process of this invention comprises contacting a fur with an acid aqueous liquor containing an acid protease from a fungus strain of the genus Rhizopus rhizopodiformis, said acid protease being effective in the pH range of from about 2.5 to 6.5.

    摘要翻译: 本发明涉及一种软化毛皮的方法,同时最大限度地保护毛发的外观。 本发明的方法包括使毛皮与含有根霉属根霉属真菌菌株的酸性蛋白酶的酸性水溶液接触,所述酸性蛋白酶在约2.5至6.5的pH范围内有效。

    Process for the manufacture of crystalline, crosslinked, elastomeric
epoxide resins
    69.
    发明授权
    Process for the manufacture of crystalline, crosslinked, elastomeric epoxide resins 失效
    制备结晶,交联,弹性体环氧树脂的方法

    公开(公告)号:US4101476A

    公开(公告)日:1978-07-18

    申请号:US828441

    申请日:1977-08-29

    IPC分类号: C08L63/00 F24J2/48 C08L91/00

    CPC分类号: F24J2/482 C08L63/00 Y02E10/40

    摘要: The invention relates to the manufacture of crystalline epoxide resins which exhibit a marked crystallite melt temperature. The formation of the crystallites is caused by molecule blocks which are derived from polyester-polycarboxylic acids, which contain aliphatic radicals in the chain. According to the invention, two aliphatic polyester-polycarboxylic acids (A and B) are reacted under very specific quantitative conditions with epoxide compounds which contain at least 2 epoxide groups and optionally with curing agents. The polyester-polycarboxylic acids A are purely n-aliphatic in character, whereas the polyester-polycarboxylic acids B are not. They contain radicals which are derived from dimerized mono- unsaturated or di- unsaturated fatty acids during the ester formation. These crystalline synthetic resins are particularly suitable for use as material for absorbing solar energy in solar energy collectors.

    摘要翻译: 本发明涉及显示出明显的微晶熔融温度的结晶环氧树脂的制造。 微晶的形成是由衍生自在链中含有脂族基团的聚酯多元羧酸的分子嵌段引起的。 根据本发明,两种脂族聚酯多元羧酸(A和B)在非常特定的定量条件下与含有至少2个环氧基团和任选地与固化剂的环氧化合物反应。 聚酯多元羧酸A的性质纯粹是正脂族的,而聚酯多元羧酸B不是。 它们含有在酯形成期间衍生自二聚单不饱和或不饱和脂肪酸的基团。 这些结晶合成树脂特别适用于太阳能收集器中吸收太阳能的材料。

    Process for the manufacturing of CRR inhibitors
    70.
    发明授权
    Process for the manufacturing of CRR inhibitors 有权
    制备CRR抑制剂的方法

    公开(公告)号:US08680280B2

    公开(公告)日:2014-03-25

    申请号:US13851547

    申请日:2013-03-27

    IPC分类号: A61K31/445 C07D211/68

    CPC分类号: C07D401/14

    摘要: The present invention relates to a process for preparing CCR3 inhibitors of formula 1, wherein R1 is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl; R2 is H, C1-6-alkyl; X is an anion selected from the group consisting of chloride or ½ dibenzoyltartrate j is 1 or 2.

    摘要翻译: 本发明涉及一种制备式1的CCR3抑制剂的方法,其中R 1是H,C 1-6 - 烷基,C 0-4 - 烷基-C 3-6环烷基,C 1-6 - 卤代烷基; R2是H,C1-6烷基; X是选自氯化物或½二苯甲酰酒石酸盐j为1或2的阴离子。