公开(公告)号：US20160083768A1

公开(公告)日：2016-03-24

申请号：US14952467

申请日：2015-11-25

Applicant: DexCom, Inc.

Inventor： Robert J. Boock ,  Monica A. Rixman ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: C12Q1/00 ,  A61B5/1486 ,  A61B5/145

CPC classification number: C12Q1/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  A61B5/14865 ,  C12Q1/006

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

公开(公告)号：US09173607B2

公开(公告)日：2015-11-03

申请号：US14169033

申请日：2014-01-30

Applicant: DexCom, Inc.

Inventor： Robert Boock ,  Monica Rixman Swinney ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/145 ,  G01N27/40 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  C12Q1/00

CPC classification number: A61B5/14865 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/72 ,  A61B5/7475 ,  B33Y70/00 ,  C12Q1/006 ,  G01N27/40

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

公开(公告)号：US20150289788A1

公开(公告)日：2015-10-15

申请号：US14250320

申请日：2014-04-10

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Bohm ,  Michael J. Estes ,  Jeff Jackson ,  Jason Mitchell ,  Jack Pryor ,  Daiting Rong ,  Sean T. Saint ,  Disha B. Sheth ,  Shanger Wang

IPC: A61B5/1473 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14532

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

Abstract translation: 提供包括可溶组织穿刺尖端的传感器装置。 传感器装置可与可配置用于将传感器装置插入到主机中的可溶解针结合使用。 还提供用于加强传感器装置上的膜的硬化剂。 还提供了使用和制造传感器装置的方法。

公开(公告)号：US08954128B2

公开(公告)日：2015-02-10

申请号：US14058154

申请日：2013-10-18

Applicant: DexCom, Inc.

Inventor： Robert J. Boock ,  Monica A. Rixman ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/1468 ,  C12Q1/00 ,  G01N27/40 ,  A61B5/1473 ,  A61B5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7203 ,  B33Y70/00 ,  C12Q1/006 ,  G01N27/40

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

Abstract translation: 描述了用于提供分析物浓度的连续测量的装置和方法。 在一些实施例中，该装置具有感测机构和感测膜，其包括至少一个含表面活性基团的聚合物并且位于感测机构上方。 感测膜可以具有生物保护层，其被配置为基本上阻挡非恒定噪声产生物质的影响和/或影响。

公开(公告)号：US20140046158A1

公开(公告)日：2014-02-13

申请号：US14058154

申请日：2013-10-18

Applicant: DexCom, Inc.

Inventor： Robert J. Boock ,  Monica A. Rixman ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7203 ,  B33Y70/00 ,  C12Q1/006 ,  G01N27/40

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

Abstract translation: 描述了用于提供分析物浓度的连续测量的装置和方法。 在一些实施例中，该装置具有感测机构和感测膜，其包括至少一个含表面活性基团的聚合物并且位于感测机构上方。 感测膜可以具有生物保护层，其被配置为基本上阻挡非恒定噪声产生物质的影响和/或影响。

公开(公告)号：US20140046149A1

公开(公告)日：2014-02-13

申请号：US14058091

申请日：2013-10-18

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Apurv Ullas Kamath ,  Matthew D. Wightlin ,  Michael J. Estes

IPC: A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C3/10

Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

Abstract translation: 提供了用于连续测量分析物浓度的装置和方法。 该装置可以包括具有多个传感器元件的传感器，每个传感器元件具有与装置的其它传感器不同的至少一个特性。 在一些实施例中，多个传感器元件各自被调谐以测量分析物浓度的不同范围，从而为器件提供在生理学相关范围内实现基本一致的测量精度水平的能力。 在其他实施例中，该装置包括多个传感器元件，每个传感器元件在插入或植入之后的不同时间期间被调整以测量，从而为传感器提供在宽范围的时间段内连续且精确地测量分析物浓度的能力。 例如，传感器系统180被提供有具有包括第一传感器元件102的第一工作电极150和包括第二传感器元件104的第二工作电极160以及用于提供用于测量工作电极电位的参考值的参考电极108 的传感器元件102,104。

公开(公告)号：US20240415430A1

公开(公告)日：2024-12-19

申请号：US18740396

申请日：2024-06-11

Applicant: Dexcom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv U Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Davis ,  Daiting Rong ,  Disha Sheth ,  Peter C Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/01 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/172 ,  G16Z99/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US12011266B2

公开(公告)日：2024-06-18

申请号：US18145220

申请日：2022-12-22

Applicant: Dexcom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Apurv Ullas Kamath ,  Matthew D. Wightlin ,  Michael J. Estes

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/1473 ,  B05C3/02 ,  B05C3/10 ,  B05C3/12 ,  B23K26/362 ,  B05C5/02 ,  B05D1/18 ,  B05D3/06 ,  B23K26/08 ,  C23C2/00

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  B05C3/02 ,  B05C3/10 ,  B05C3/125 ,  B23K26/362 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C5/0241 ,  B05D1/18 ,  B05D3/06 ,  B23K26/0823 ,  B29C2791/009 ,  C23C2/00

Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

公开(公告)号：US20240049998A1

公开(公告)日：2024-02-15

申请号：US18494559

申请日：2023-10-25

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Bohm ,  Michael J. Estes ,  Jeff Jackson ,  Jason Mitchell ,  Jack Pryor ,  Daiting Rong ,  Sean T. Saint ,  Disha B. Sheth ,  Shanger Wang

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/00 ,  A61B17/34

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/6848 ,  A61B5/4839 ,  A61B17/3468 ,  A61B2017/00004

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

公开(公告)号：US20240000352A1

公开(公告)日：2024-01-04

申请号：US18217338

申请日：2023-06-30

Applicant: Dexcom, Inc.

Inventor： Robert Boock ,  Monica Rixman Swinney ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/1486 ,  A61B5/1473 ,  A61B5/145 ,  G01N27/40 ,  A61B5/1468 ,  C12Q1/00

CPC classification number: A61B5/14865 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14546 ,  G01N27/40 ,  A61B5/1468 ,  A61B5/14532 ,  C12Q1/006 ,  B33Y70/00

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.