公开(公告)号：US07412991B2

公开(公告)日：2008-08-19

申请号：US11270595

申请日：2005-11-10

申请人： Keiichi Takimoto ,  Ikuo Ueda ,  Masakazu Murakami

发明人： Keiichi Takimoto ,  Ikuo Ueda ,  Masakazu Murakami

IPC分类号： D21F7/08 ,  D03D25/00

CPC分类号： D21F1/0036 ,  Y10T442/3195

摘要： In an industrial two-layer fabric, either one of an upper side binding yarn and a lower surface binding yarn constituting a pair to be woven with an upper surface weft and a lower side weft passes under one lower surface weft and then passes over a plurality of lower surface wefts. A warp on one adjacent side of the one of the upper and lower surface binding yarns has a similar design thereto and passes over and under the same lower surface wefts. The design of a set of the two warps adjacent to each other is shifted and arranged one after another to form a complete design of the lower surface fabric and a lower surface weft has a design in which the weft passes over two successive warps and then passes under a plurality of warps to form a long crimp on the lower surface.

摘要翻译： 在工业双层织物中，构成一对上面纬纱和下侧纬纱的上侧粘合纱和下表面捆扎纱中的任一个在一个下表面纬纱下通过，然后通过多个 的下表面纬纱。 上表面和下表面装订纱之一的一个相邻侧上的经线具有类似的设计，并且在相同的下表面纬纱下方经过。 相邻的两个经线的设计被一个接一个地移位和排列，以形成下表面织物的完整设计，并且下表面纬纱具有其中纬纱经过两个连续经线然后通过的设计 在多个经纱下，在下表面形成长卷曲。

公开(公告)号：US07357157B2

公开(公告)日：2008-04-15

申请号：US11451560

申请日：2006-06-13

申请人： Ikuo Ueda

发明人： Ikuo Ueda

IPC分类号： D21F7/08 ,  D03D25/00

CPC分类号： D21F1/0036 ,  Y10S162/903

摘要： In a repeating unit of a two-layer fabric, a first upper surface side warp forms a first upper surface side warp design. A second upper surface side warp forms a latent portion in which the second upper surface side warp passes between the two layers of the fabric. A first lower warp binding yarn and a second lower warp binding yarn form first and second knuckles respectively by passing over one or two upper surface side wefts at a position not adjacent to two knuckles of the second upper surface side warp in the latent portion. The first and second knuckles are formed at different positions. The first lower warp binding yarn, second upper surface side warp and second lower warp binding yarn cooperatively form a second upper surface side warp design similar to the first upper surface side warp design.

摘要翻译： 在双层织物的重复单元中，第一上表面侧翘曲形成第一上表面侧翘曲设计。 第二上表面侧翘曲形成潜在部分，第二上表面侧经线在织物的两层之间经过。 第一下经纱装订纱线和第二下经纱装订纱线分别通过在潜在部分中不邻近第二上表面侧翘曲的两个指关节的位置上穿过一个或两个上表面侧纬纱而形成第一和第二转向节。 第一和第二关节形成在不同的位置。 第一下部经向结合纱线，第二上部表面侧经纱和第二下部经向结合纱线协同地形成类似于第一上部表面侧经纱设计的第二上部表面侧经纱设计。

公开(公告)号：US07108019B2

公开(公告)日：2006-09-19

申请号：US10443061

申请日：2003-05-22

申请人： Hiroyuki Nagura ,  Ikuo Ueda ,  Shigenobu Fujisawa

发明人： Hiroyuki Nagura ,  Ikuo Ueda ,  Shigenobu Fujisawa

IPC分类号： D03D11/00

CPC分类号： D21F1/0036 ,  Y10S162/90 ,  Y10S162/902

摘要： An industrial two-layer fabric comprises an upper layer fabric having upper surface side warps and upper surface side wefts and a lower layer fabric having lower surface side warps and lower surface side wefts. The upper layer fabric and the lower layer fabric are bound at least one spot in a repeating unit where an upper surface side warp weaves a lower surface side weft without weaving an upper surface side weft which should have been woven by the upper surface side warp based on the fabric structure, and where a lower surface side warp weaves the upper surface side weft which should have been woven by the upper surface side warp, without weaving the lower surface side weft which should have been woven by the lower surface side warp.

公开(公告)号：US5340725A

公开(公告)日：1994-08-23

申请号：US13204

申请日：1993-02-01

申请人： Ikuo Ueda ,  Mineo Niwa ,  Yoshimasa Saito ,  Yoshinori Ishii ,  Tadashi Hitaguchi

发明人： Ikuo Ueda ,  Mineo Niwa ,  Yoshimasa Saito ,  Yoshinori Ishii ,  Tadashi Hitaguchi

IPC分类号： C07K14/59 ,  C07K14/65 ,  C12N15/70 ,  C12N15/00 ,  C12N5/00

CPC分类号： C12N15/70 ,  C07K14/59 ,  C07K14/65 ,  C07K2319/00 ,  C07K2319/35 ,  C07K2319/75

摘要： Two-cistronic Met-IGF-I expression vector, in which the first cistron encodes a protective peptide with a molecular weight of about 500-50,000 and the second cistron encodes IGF-I, was provided. Also provided is a process for preparing Met-IGF-I, which comprises transforming E. coli with said vector and growing the resultant transformant, followed by the lysis of the cell culture and isolation of Met-IGF-I.

摘要翻译： 提供了两顺反子Met-IGF-1表达载体，其中第一顺式编码分子量为约500-50,000的保护性肽，第二顺反子编码IGF-I。 还提供了制备Met-IGF-1的方法，其包括用所述载体转化大肠杆菌并生长所得转化体，随后细胞培养物的裂解和Met-IGF-I的分离。

公开(公告)号：US5019500A

公开(公告)日：1991-05-28

申请号：US217885

申请日：1988-07-11

申请人： Ikuo Ueda ,  Mineo Niwa ,  Yoshimasa Saito ,  Susumu Sato ,  Hiroki Ono ,  Tadashi Kitaguchi

发明人： Ikuo Ueda ,  Mineo Niwa ,  Yoshimasa Saito ,  Susumu Sato ,  Hiroki Ono ,  Tadashi Kitaguchi

IPC分类号： C07K1/12 ,  C07K14/00 ,  C07K14/57 ,  C07K14/575 ,  C07K14/65 ,  C07K19/00 ,  C12N1/21 ,  C12N15/09 ,  C12N15/71 ,  C12P21/02 ,  C12R1/19

CPC分类号： C07K14/57 ,  C07K14/65 ,  C12N15/71 ,  C07K2319/00 ,  C07K2319/35 ,  C07K2319/75

摘要： IGF-I fused with a protective peptide, in which the protective peptide is a protein peptide and is used for the protection of IGF-I from degradation by protease in cells of E. coli is disclosed. Also disclosed are genes coding for the fused IGF-I's, plasmids containing the genes, and E. coli microorganisms transformed with the plasmids.

摘要翻译： IGF-I与保护性肽融合，其中保护性肽是蛋白质肽，并且用于保护IGF-1免受大肠杆菌细胞中的蛋白酶降解。 还公开了编码融合的IGF-I，含有这些基因的质粒和用质粒转化的大肠杆菌微生物的基因。

公开(公告)号：US4767780A

公开(公告)日：1988-08-30

申请号：US42299

申请日：1987-04-24

申请人： Ikuo Ueda ,  Youichi Shiokawa ,  Takashi Manabe ,  Yousuke Katsura

发明人： Ikuo Ueda ,  Youichi Shiokawa ,  Takashi Manabe ,  Yousuke Katsura

IPC分类号： C07D311/22 ,  A61K31/415 ,  A61K31/4162 ,  A61K31/435 ,  A61K31/47 ,  A61K31/4745 ,  A61P7/10 ,  A61P9/02 ,  A61P9/08 ,  A61P9/12 ,  A61P19/06 ,  C07D215/22 ,  C07D215/233 ,  C07D215/38 ,  C07D311/56 ,  C07D471/04 ,  C07D491/04 ,  C07D491/052 ,  A61K31/35 ,  C07D487/04

CPC分类号： C07D215/233 ,  C07D311/56 ,  C07D471/04 ,  C07D491/04

摘要： This invention provides a benezene-fused heterocyclic compound of the formula: ##STR1## wherein R.sup.1 is halogen, nitro, amino, hydroxy, lower alkyl, lower alkoxy substituted by carboxy or protected carboxy, acylamino which may have lower alkyl on the amino moiety, or aryloxy which may have halogen,R.sup.2 is hydrogen or halogen,X is --O-- or ##STR2## in which R.sup.3 is hydrogen, lower alkyl or acyl and A is a group of the formula: ##STR3## in which R.sup.4 is hydrogen, lower, alkenyl, lower alkynyl or alkyl which may have suitable substituent(s) selected from the groups consisting of hydroxy, acyl, lower alkoxy, di(lower)alkylamino, carboxy, protected carboxy and aryl; orR.sup.1 is hydrogen or lower alkoxy,R.sup.2 is hydrogen,X is ##STR4## in which R.sub.a.sup.3 is lower alkanoyl and A is a group of the formula: ##STR5## and pharmaceutically acceptable salts thereof. This compound possesses diuretic activity, uricosuric activity and vasodilative activity and are useful as a diuretic agent, uricosuric agent and anti-hypertensive agent. The invention further relates to processes for the preparation of this compound and pharmaceutical composition comprising compound of the above formula.

公开(公告)号：US4703046A

公开(公告)日：1987-10-27

申请号：US72990

申请日：1979-09-06

申请人： Ikuo Ueda ,  Masakazu Kobayashi ,  Tadashi Kitaguchi

发明人： Ikuo Ueda ,  Masakazu Kobayashi ,  Tadashi Kitaguchi

IPC分类号： A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D501/04 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36

CPC分类号： C07D277/587

摘要： This invention concerns antibiotic cephalosporins of the formula ##STR1## wherein R.sup.1 is amino or protected amino; R.sup.2 is halogen; R.sup.3 is alkyl; and R.sup.6 is carboxy or protected carboxy.

摘要翻译： 本发明涉及式IMA的抗生素头孢菌素，其中R1是氨基或被保护的氨基; R2是卤素; R3是烷基; 并且R 6是羧基或被保护的羧基。

公开(公告)号：US4613608A

公开(公告)日：1986-09-23

申请号：US731893

申请日：1985-05-08

申请人： Ikuo Ueda ,  Daizo Morino ,  Koichi Takimoto

发明人： Ikuo Ueda ,  Daizo Morino ,  Koichi Takimoto

IPC分类号： A61K31/44 ,  A61K31/4402 ,  A61K31/4409 ,  A61K31/4418 ,  A61P9/08 ,  A61P9/10 ,  C07D213/30 ,  C07D213/61 ,  C07D213/53

CPC分类号： C07D213/30 ,  C07D213/61

摘要： Compounds of the formula ##STR1## are disclosed whereinR.sup.1 is hydrogen or lower alkyl, one of R.sup.2 and R.sup.3 is mono (or di)-nitroxy(lower)alkyl and the otherR.sup.2 and R.sup.3 is hydrogen and pharmaceutically acceptable salts thereof.Also disclosed are vasodilating compositions containing the above.

公开(公告)号：US4608375A

公开(公告)日：1986-08-26

申请号：US622881

申请日：1984-06-21

申请人： Ikuo Ueda ,  Masayuki Kato

发明人： Ikuo Ueda ,  Masayuki Kato

IPC分类号： A61K31/505 ,  A61K31/517 ,  A61P37/08 ,  C07D239/95 ,  C07D239/96 ,  C07D243/00 ,  C07D243/08 ,  C07D403/06 ,  C07D403/12 ,  A61K31/445 ,  C07D239/82

CPC分类号： C07D403/06 ,  C07D239/95 ,  C07D239/96 ,  C07D243/08 ,  C07D403/12 ,  Y10S514/826

摘要： The present invention relates to novel quinazolinone derivatives and pharmaceutically acceptable salts thereof. More particularly, it relates to novel quinazolinone derivatives and pharmaceutically acceptable salts thereof which have antiallergic activities, to processes for the preparation thereof, to pharmaceutical composition comprising the same, and to a method of using the same therapeutically in the treatment of allergic symptoms in human being and animals.

摘要翻译： 本发明涉及新颖的喹唑啉酮衍生物及其药学上可接受的盐。 更具体地说，本发明涉及具有抗过敏活性的新颖的喹唑啉酮衍生物及其药学上可接受的盐，其制备方法，包含其的药物组合物，以及在治疗人类过敏症状中的治疗用途的方法 存在和动物。

公开(公告)号：US4563455A

公开(公告)日：1986-01-07

申请号：US587981

申请日：1984-03-09

申请人： Ikuo Ueda ,  Masayuki Kato ,  Masanobu Nagano ,  Atsushi Akahane

发明人： Ikuo Ueda ,  Masayuki Kato ,  Masanobu Nagano ,  Atsushi Akahane

IPC分类号： A61K31/415 ,  A61P1/04 ,  C07D235/10 ,  C07D235/12 ,  C07D401/06 ,  C07D403/06 ,  C07D417/06 ,  C07D471/04 ,  C07D521/00 ,  A61K31/53

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D235/10 ,  C07D235/12 ,  C07D249/08 ,  C07D401/06 ,  C07D403/06 ,  C07D417/06 ,  C07D471/04

摘要： New fused imidazole compounds of the formula: ##STR1## wherein A is lower alkylene,R.sup.1 is hydrogen, lower alkyl, lower alkoxy or halogen,R.sup.2 is hydrogen, lower alkyl, cyclo(lower)alkyl, pyridyl, ar(lower)alkyl which may be substituted with halogen, or aryl which may be substituted with lower alkyl, lower alkoxy, hydroxy or halogen,R.sup.3 is N-containing unsaturated heterocyclic group which may be substituted with lower alkyl or amino, andY is .dbd.C-- or .dbd.N--,and pharmaceutically acceptable salts thereof, and processes for preparation thereof and pharmaceutical composition comprising the same.These derivatives and salts thereof are useful as antiulcer agents.

摘要翻译： 其中A为低级亚烷基，R 1为氢，低级烷基，低级烷氧基或卤素，R 2为氢，低级烷基，环（低级）烷基，吡啶基，Ar（低级）烷基， 可以被卤素取代，或可以被低级烷基，低级烷氧基，羟基或卤素取代的芳基，R3是可被低级烷基或氨基取代的含N不饱和杂环基，Y是=或= N - 及其药学上可接受的盐，及其制备方法和包含其的药物组合物。 这些衍生物和其盐可用作抗溃疡剂。