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    External activation of vaso-occlusive implants
    61.
    发明授权
    External activation of vaso-occlusive implants 失效
    血管闭塞植入物的外部激活

    公开(公告)号：US07789891B2

    公开(公告)日：2010-09-07

    申请号：US10669543

    申请日：2003-09-23

    申请人： Michael P. Wallace

    发明人： Michael P. Wallace

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12154 ,  A61B18/08 ,  A61B2017/005 ,  A61B2090/374

    摘要： A vaso-occlusive device is introduced in a cavity of a patient's vasculature, such as an aneurysm, after which an external energy source, such as a MRI machine is activated to heat the vaso-occlusive device to assist in forming a thrombus or embolism within the treatment site, to release and/or activate a diagnostic or therapeutic agent carried by the vaso-occlusive device, and/or to fuse together portions of the vaso-occlusive device to help stabilize the device in a three-dimensional shape.

    摘要翻译： 将血管闭塞装置引入患者脉管系统的腔中，例如动脉瘤，之后激活诸如MRI机器的外部能量源以加热血管闭塞装置以协助形成血栓或栓塞 治疗部位释放和/或激活由血管闭塞装置携带的诊断或治疗剂，和/或将血管闭塞装置的部分熔合在一起以帮助将装置稳定在三维形状。

    Vaso-occlusive device having pivotable coupling
    63.
    发明授权
    Vaso-occlusive device having pivotable coupling 失效
    具有可枢转耦合的血管闭塞装置

    公开(公告)号：US07608089B2

    公开(公告)日：2009-10-27

    申请号：US11022189

    申请日：2004-12-22

    申请人： Michael P. Wallace ,  Kamal Ramzipoor

    发明人： Michael P. Wallace ,  Kamal Ramzipoor

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/12054 ,  A61B2017/12063 ,  A61B2017/12095

    摘要： An assembly for occluding a vascular site (e.g., an aneurysm) of a human or veterinary patient includes a vaso-occlusive member, a pusher member having a distal end and a severable junction located proximal to the distal end, and a pivotable coupling that couples the pusher member to the occlusive member. A delivery catheter can be used to deliver the vaso-occlusive member to the vascular site. A method of using the assembly to occlude an aneurysm having an aneurysmal sac and an aneurysmal neck, includes locating the catheter within the aneurysmal neck, and manipulating the pusher member to place the vaso-occlusive member within the aneurysmal sac. The method further includes severing the severable junction to detach the vaso-occlusive member from the pusher member. As a result, an axial force is applied by the vaso-occlusive member in a proximal direction, which buckles the pivotable coupling to laterally deflect the axial force. The lateral deflection of the axial force caused by the buckling of the pivotable coupling prevents the catheter from being displaced from the aneurysmal neck by the axial force.

    摘要翻译： 用于闭塞人或兽医患者的血管部位（例如，动脉瘤）的组件包括血管闭塞构件，具有远端的推动器构件和位于远端附近的可分离接合部以及可枢转联接件 推动器构件到闭塞构件。 输送导管可用于将血管闭塞成员递送至血管部位。 一种使用组件闭塞具有动脉瘤囊和动脉瘤颈部的动脉瘤的方法，包括将导管定位在动脉瘤颈内，以及操纵推动器构件以将血管闭塞构件置于动脉瘤囊内。 该方法还包括切断可分开的连接处以将血管闭塞构件与推动器构件分离。 结果，轴向力由近端方向由血管闭塞构件施加，该近侧方向使可枢转联接器弯曲以横向偏转轴向力。 由可枢转联轴器的弯曲引起的轴向力的横向偏转防止导管通过轴向力从动脉瘤颈部移位。

    Vaso-occlusive coils with non-overlapping sections
    64.
    发明授权
    Vaso-occlusive coils with non-overlapping sections 失效
    具有非重叠部分的血管闭塞线圈

    公开(公告)号：US07488332B2

    公开(公告)日：2009-02-10

    申请号：US10791092

    申请日：2004-03-01

    申请人： Clifford Teoh ,  Michael P. Wallace

    发明人： Clifford Teoh ,  Michael P. Wallace

    IPC分类号： A61B17/24

    CPC分类号： A61B17/12113 ,  A61B17/12022 ,  A61B17/12145 ,  A61B2017/00526

    摘要： A vaso-occlusive implant has a primary helical-coil shape that defines a primary axis and a three-dimensional secondary shape. The secondary shape includes a substantially helical section and a second section having a plurality of non-overlapping loops or loop sections. Each loop defines a plane that is oriented at an angle from about 30-150 degrees relative to a plane defined by an immediately preceding or immediately succeeding loop along the primary axis. The coil sections or loops can be generally circular loops or other smooth shapes.

    摘要翻译： 血管闭塞植入体具有限定主轴线和三维二次形状的初级螺旋线圈形状。 次级形状包括基本上螺旋的部分和具有多个非重叠环或环部分的第二部分。 每个环限定了相对于由紧邻的前一个或紧随其后的环沿主轴定义的平面以大约30-150度的角度定向的平面。 线圈段或环可以是大体圆环或其它平滑形状。

    Modular steerable sheath catheters
    65.
    发明授权
    Modular steerable sheath catheters 有权
    模块化导向鞘导管

    公开(公告)号：US07481793B2

    公开(公告)日：2009-01-27

    申请号：US10733922

    申请日：2003-12-10

    申请人： Robert M. Abrams ,  Michael P. Wallace

    发明人： Robert M. Abrams ,  Michael P. Wallace

    IPC分类号： A61M5/178

    CPC分类号： A61M25/0662 ,  A61M25/10 ,  A61M2025/0006 ,  A61M2025/0293 ,  A61M2025/0681 ,  A61M2025/09125 ,  A61M2025/1063

    摘要： An apparatus for accessing a site within a body includes a cannula and an elongate member. The cannula has a proximal end, a distal end, and a lumen extending therebetween. The elongate member has a distal end configured for insertion into the lumen, wherein the distal end of the elongate member is attachable to and releasable from the distal end of the cannula. A method for accessing a site within a body includes inserting a distal end of an elongate member into a lumen of a cannula, detachably attaching the distal end of the elongate member to the cannula, and steering a distal end of the cannula to a desired site using the elongate member.

    摘要翻译： 用于进入体内部位的装置包括套管和细长构件。 套管具有近端，远端和在其间延伸的内腔。 细长构件具有构造成用于插入内腔的远端，其中细长构件的远端可附接到插管的远端并且可从插管的远端释放。 用于访问体内部位的方法包括将细长构件的远端插入套管的内腔，将细长构件的远端可拆卸地连接到套管上，并将套管的远端转向所需位置 使用细长构件。

    Method of stimulating fastigium nucleus to treat neurological disorders
    67.
    发明授权
    Method of stimulating fastigium nucleus to treat neurological disorders 有权
    刺激ium核治疗神经系统疾病的方法

    公开(公告)号：US07286879B2

    公开(公告)日：2007-10-23

    申请号：US10893076

    申请日：2004-07-16

    申请人： Michael P. Wallace

    发明人： Michael P. Wallace

    IPC分类号： A61N1/05

    CPC分类号： A61N1/36082 ,  A61N1/36103

    摘要： A method of treating a neurological disorder (such as acute stroke) in a patient is provided. The method comprises introducing an electrical stimulation lead within the patient's head, advancing the stimulation lead within an intracranial vascular body, such as a blood vessel or ventricle, placing the stimulation lead adjacent the fastigium nucleus of the patient's brain, and stimulating the fastigium nucleus with the stimulation lead to treat the neurological disorder.

    摘要翻译： 提供了治疗患者的神经障碍（例如急性中风）的方法。 该方法包括在患者头部内引入电刺激引线，将刺激引线推进到颅内血管体（例如血管或心室）内，将刺激引线放置在患者脑部的快速核附近，并用刺激引线刺激fastigium细胞核 刺激导致治疗神经系统疾病。

    Intravascular self-anchoring electrode body with arcuate springs, spring loops, or arms
    68.
    发明授权
    Intravascular self-anchoring electrode body with arcuate springs, spring loops, or arms 有权
    血管内自身锚定电极主体具有弧形弹簧，弹簧环或手臂

    公开(公告)号：US07231260B2

    公开(公告)日：2007-06-12

    申请号：US10841070

    申请日：2004-05-06

    申请人： Michael P. Wallace ,  Robert J. Garabedian ,  Wendelin C. Maners ,  Robert Abrams

    发明人： Michael P. Wallace ,  Robert J. Garabedian ,  Wendelin C. Maners ,  Robert Abrams

    IPC分类号： A61N1/00

    CPC分类号： A61N1/057 ,  A61N1/3787 ,  A61N2001/0585

    摘要： An expandable intravascular medical device comprises an arcuate spring configured to be expanded into contact with the inner surface of a blood vessel. Another medical device comprises an electrode support structure, e.g., a non-tubular arcuate structure or a cylindrical member, and a plurality of resilient spring loops laterally extending from the support structure. The contact created between the loops and a blood vessel is sufficient to anchor the medical device within the blood vessel. In another embodiment, the medical device comprises an elongated member and two resilient spring arms extending distally from the elongated member. The arms are configured to be laterally moved towards each other to place the medical device in a collapsed geometry, and configured to be laterally moved away from each into contact with an inner surface of a blood vessel to place the medical device an expanded geometry.

    摘要翻译： 可扩张血管内医疗装置包括弓形弹簧，其被构造成膨胀成与血管的内表面接触。 另一医疗装置包括电极支撑结构，例如非管状弓形结构或圆柱形构件，以及从支撑结构横向延伸的多个弹性弹簧环。 在环和血管之间产生的接触足以将医疗装置锚定在血管内。 在另一个实施例中，医疗装置包括细长构件和从细长构件向远侧延伸的两个弹性弹簧臂。 臂被配置为朝向彼此横向移动以将医疗装置放置在折叠的几何形状中，并且被构造成横向移动远离每个与血管的内表面接触，以将医疗装置放置成扩展的几何形状。

    Collapsible/expandable electrode leads
    69.
    发明授权
    Collapsible/expandable electrode leads 有权
    可折叠/可扩展电极引线

    公开(公告)号：US07177702B2

    公开(公告)日：2007-02-13

    申请号：US10799270

    申请日：2004-03-12

    申请人： Michael P. Wallace ,  Robert J. Garabedian ,  Alex Leynov

    发明人： Michael P. Wallace ,  Robert J. Garabedian ,  Alex Leynov

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0553 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0558

    摘要： A medical lead and method of treating a patient are provided. The medical lead comprises an electrically insulative membrane, a resilient spring element associated with the insulative membrane, and at least one electrode associated with the insulative membrane. The spring layer is configured to urge that insulative membrane into an expanded geometry. The medical lead is configured to be collapsed into a compact form for percutaneous delivery into the patient, thereby obviating the need to perform an invasive surgical procedure on the patient. The patient can be treated by placing the medical lead into a collapsed state by applying a compressive force to the medical lead, percutaneously delivering the collapsed medical lead into the patient adjacent tissue to be treated, and placing the medical lead into an expanded state by releasing the compressive force.

    摘要翻译： 提供医疗用铅和治疗患者的方法。 医用引线包括电绝缘膜，与绝缘膜相关联的弹性弹簧元件，以及与绝缘膜相关联的至少一个电极。 弹簧层构造成将绝缘膜推动成扩展的几何形状。 医疗用引线被构造成塌缩成紧密形式用于经皮输送到患者体内，从而避免了对患者执行侵入性外科手术的需要。 可以通过向医用引线施加压缩力将医用引线置于折叠状态来将患者放置在患者身体中，将经塌陷的医用导管经皮递送到邻近被治疗组织的患者中，并通过释放将医用引线放入扩张状态 压缩力。