公开(公告)号：US08321141B2

公开(公告)日：2012-11-27

申请号：US12291999

申请日：2008-11-14

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N33/48

CPC分类号： G01N33/02 ,  A47G19/2205 ,  A47G21/02 ,  A47G21/04 ,  A47G21/103

摘要： A system may include utensil means for portioning a foodstuff into a first portion and a second portion, a means for detecting a first portion size for the first portion with the utensil means, a means for detecting a second portion size for the second portion with the utensil means, and a means for determining a cumulative amount of portioned foodstuff based upon the first portion size and the second portion size.

公开(公告)号：US08285488B2

公开(公告)日：2012-10-09

申请号：US12313027

申请日：2008-11-14

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N33/48

CPC分类号： G01G19/40 ,  G01G19/56 ,  G01G23/3735

摘要： A system may include utensil means for portioning a foodstuff into a first portion and a second portion, a means for detecting a first portion size for the first portion with the utensil means, a means for detecting a second portion size for the second portion with the utensil means, and a means for determining a cumulative amount of portioned foodstuff based upon the first portion size and the second portion size.

公开(公告)号：US08784368B2

公开(公告)日：2014-07-22

申请号：US12590856

申请日：2009-11-13

申请人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61M5/30

CPC分类号： A61K31/192 ,  A61B5/1116 ,  A61B5/112 ,  A61B5/1126 ,  A61B5/4528 ,  A61K31/195 ,  A61M37/0015 ,  A61M2005/3022 ,  A61M2037/0007 ,  A61M2037/0023 ,  A61M2037/0061

摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more sheaths configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more applicators supported by the one or more sheaths and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.

摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括构造成接触哺乳动物受试者的关节骨的一个或多个关节附近的一个或多个身体轮廓的一个或多个护套; 一个或多个传感器被配置为检测所述一个或多个关节的一个或多个生理状况; 以及由所述一个或多个护套支撑并且被配置为通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应所述一个或多个传感器的一个或多个施用器。

公开(公告)号：US08926584B2

公开(公告)日：2015-01-06

申请号：US12660112

申请日：2010-02-19

申请人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61M31/00 ,  A61K31/192 ,  A61K31/195

CPC分类号： A61K31/192 ,  A61K31/195

摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more substrates configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to monitor movement of the one or more body contours; and one or more applicators supported by the one or more substrates and configured to respond to the movement of the one or more body contours by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.

摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括被配置为接触靠近哺乳动物受试者的关节骨的一个或多个关节的一个或多个身体轮廓的一个或多个基底; 一个或多个传感器被配置为监测所述一个或多个身体轮廓的运动; 以及一个或多个施用器，由一个或多个基底支撑并且构造成通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应一个或多个身体轮廓的移动。

公开(公告)号：US08888761B2

公开(公告)日：2014-11-18

申请号：US12590858

申请日：2009-11-13

申请人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61K9/22 ,  A61K31/195 ,  A61K31/192

CPC分类号： A61K31/192 ,  A61B5/1116 ,  A61B5/112 ,  A61B5/1126 ,  A61B5/4528 ,  A61K31/195 ,  A61M37/0015 ,  A61M2005/3022 ,  A61M2037/0007 ,  A61M2037/0023 ,  A61M2037/0061

摘要： A device, a system, or a method is described for treating a disease or condition of one or more joints of articulating bone in a mammalian subject. A device is described which includes one or more substrates configured to contact one or more body contours at one or more joints of articulating bone of a mammalian subject; and an applicator supported by the one or more substrates and configured to inject one or more medicaments to one or more joint tissues of the mammalian subject.

摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 描述了一种装置，其包括被配置为接触哺乳动物受试者的关节骨的一个或多个关节处的一个或多个身体轮廓的一个或多个基底; 以及由所述一个或多个基底支撑并且构造成将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织的施用器。

公开(公告)号：US08444622B2

公开(公告)日：2013-05-21

申请号：US12660110

申请日：2010-02-19

申请人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Philip A. Eckhoff ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61M31/00

CPC分类号： A61B5/1126 ,  A61B5/01 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/112 ,  A61B5/441 ,  A61B5/4528 ,  A61B5/4866 ,  A61B5/6843 ,  A61B6/505 ,  A61B8/0875 ,  A61B8/4472 ,  A61M5/14248 ,  A61M37/0015 ,  A61M2005/3022 ,  A61M2037/0023 ,  A61M2037/0061

摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes an enclosure including one or more sensors, a controller, and one or more applicators configured to surround one or more joints of articulating bone of a mammalian subject, wherein the one or more sensors are configured to detect one or more physiological conditions of the one or more joints of the mammalian subject, and the controller, configured to communicate with the one or more sensors, is configured to activate the one or more applicators, and wherein the one or more applicators are configured to inject one or more medicaments to one or more joint tissues of the mammalian subject.

公开(公告)号：US08392125B2

公开(公告)日：2013-03-05

申请号：US12313025

申请日：2008-11-14

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N33/48

CPC分类号： A47G21/00 ,  G01G19/4146 ,  G01G23/3735 ,  G01N33/02

摘要： A system may include utensil means for portioning a foodstuff into a first portion and a second portion, a means for detecting a first portion size for the first portion with the utensil means, a means for detecting a second portion size for the second portion with the utensil means, and a means for determining a cumulative amount of portioned foodstuff based upon the first portion size and the second portion size.

公开(公告)号：US08386185B2

公开(公告)日：2013-02-26

申请号：US12313006

申请日：2008-11-14

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N33/48

CPC分类号： A47G21/04 ,  A47G23/12

摘要： A system may include utensil means for portioning a foodstuff into a first portion and a second portion, a means for detecting a first portion size for the first portion with the utensil means, a means for detecting a second portion size for the second portion with the utensil means, and a means for determining a cumulative amount of portioned foodstuff based upon the first portion size and the second portion size.

公开(公告)号：US09617157B2

公开(公告)日：2017-04-11

申请号：US12322367

申请日：2009-01-30

申请人： Mahalaxmi Gita Bangera ,  Ed Harlow ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Mahalaxmi Gita Bangera ,  Ed Harlow ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： B82Y40/00 ,  C01B31/02 ,  B82Y30/00

CPC分类号： C07K16/32 ,  A61K38/1703 ,  A61K38/1732 ,  A61K47/60 ,  A61K47/6871 ,  A61K47/6901 ,  B82Y5/00 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B21/0648 ,  C01B32/168 ,  C01B32/174 ,  C01B2202/02 ,  C01B2202/34 ,  C01B2202/36 ,  C01P2004/13 ,  Y02A50/473 ,  Y10S977/743 ,  Y10S977/75 ,  Y10S977/762 ,  Y10S977/788 ,  Y10S977/795 ,  Y10S977/848 ,  Y10S977/896 ,  Y10S977/915

摘要： Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.

公开(公告)号：US20120035440A1

公开(公告)日：2012-02-09

申请号：US13136680

申请日：2011-08-05

申请人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Thomas J. Nugent, JR. ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y. H. Wood

发明人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Thomas J. Nugent, JR. ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y. H. Wood

IPC分类号： A61B5/07

CPC分类号： A61B1/041 ,  A61B1/00156 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/0071 ,  A61B5/01 ,  A61B5/02007 ,  A61B5/0215 ,  A61B5/026 ,  A61B5/03 ,  A61B5/062 ,  A61B5/07 ,  A61B5/073 ,  A61B5/076 ,  A61B5/082 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4064 ,  A61B5/411 ,  A61B5/418 ,  A61B5/4839 ,  A61B5/6852 ,  A61B7/00 ,  A61B10/0045 ,  A61B10/04 ,  A61B17/22 ,  A61B17/22012 ,  A61B18/20 ,  A61B34/73 ,  A61B2010/0077 ,  A61B2010/0225 ,  A61B2017/00022 ,  A61B2017/00345 ,  A61F2/82 ,  A61N1/406 ,  A61N7/00 ,  G06F19/00 ,  G16H40/67

摘要： Methods of controlling the operation of a device traveling in a body tube tree, including sensing parameters from possible directions of travel and selecting the direction of travel based on the sensed parameters, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.

摘要翻译： 控制在体管树中行进的装置的操作的方法，包括从可能的行进方向感测参数以及基于所感测的参数来选择行进方向，所述方法由部分地或完全位于流明行进装置上的控制系统实现。 可以通过该设备执行各种动作，例如医疗或治疗目的。 还描述了包括用于执行方法的指令的机器可读介质。