公开(公告)号：US20100267570A1

公开(公告)日：2010-10-21

申请号：US12746992

申请日：2008-04-17

申请人： Yo Han Choi ,  Moon Youn Jung ,  Seon Hee Park

发明人： Yo Han Choi ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： C40B30/00 ,  C40B60/12

CPC分类号： G01N33/54373 ,  C40B30/00 ,  G01N21/553

摘要： A Positional Scanning—Synthetic Peptide Combinatorial Library (PS-SPC) searching apparatus and method using Surface Plasmon Resonance (SPR) are provided. The method includes spotting and fixing each of a plurality of peptide pools to a top of one thin metal film, inputting specific materials to the top of the thin metal film, applying a TM-mode light to a bottom of the thin metal film and exciting SPR for the thin metal film, and detecting a TM mode reflected light reflected from the thin metal film and displaying the detected light as a two-dimensional image.

摘要翻译： 提供了使用表面等离子体共振（SPR）的位置扫描合成肽组合库（PS-SPC）搜索装置和方法。 该方法包括将多个肽池中的每一个点样并固定到一个薄金属膜的顶部，将特定材料输入到金属薄膜的顶部，向薄金属膜的底部施加TM模式的光，并激发 SPR，并且检测从薄金属膜反射的TM模式反射光，并将检测到的光显示为二维图像。

公开(公告)号：US20100261244A1

公开(公告)日：2010-10-14

申请号：US12743340

申请日：2008-06-05

申请人： Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park ,  Hyun Sung Ko ,  Chul Huh ,  Kyung Hyun Kim ,  Jong Cheol Hong

发明人： Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park ,  Hyun Sung Ko ,  Chul Huh ,  Kyung Hyun Kim ,  Jong Cheol Hong

IPC分类号： C12N11/02 ,  C07F7/28 ,  C07H21/02 ,  C07H21/04 ,  C07K14/00

CPC分类号： G01N33/54346 ,  B82Y5/00 ,  B82Y15/00 ,  G01N33/54353 ,  G01N33/553

摘要： There is provided a method for immobilizing a bio-material on a surface of titanium dioxide nanoparticles (TiO2) as a highly reflective material to enhance sensitivity of a resonant reflection biosensor. The method for immobilizing a bio-material may be useful to easily immobilize bio-materials such as proteins, DNA, RNA and enzymes on surfaces of titanium dioxide (TiO2) nanoparticles using the chemical reaction, and significantly improve sensitivity of a resonant reflection biosensor by determining the antigen-antibody reaction in the resonant reflection biosensor using the immobilized secondary antien.

摘要翻译： 提供了将生物材料固定在作为高反射材料的二氧化钛纳米粒子（TiO 2）的表面上以提高共振反射生物传感器的灵敏度的方法。 用于固定生物材料的方法可用于使用化学反应容易地将生物材料如蛋白质，DNA，RNA和酶固定在二氧化钛（TiO 2）纳米颗粒的表面上，并且通过以下方式显着提高共振反射生物传感器的灵敏度 使用固定化的次级抗原测定共振反射生物传感器中的抗原 - 抗体反应。

公开(公告)号：US07403891B2

公开(公告)日：2008-07-22

申请号：US10777072

申请日：2004-02-13

申请人： Soo Jun Park ,  Tae Hyun Kim ,  Hyun Sook Lee ,  Hyun Chul Jang ,  Seon Hee Park

发明人： Soo Jun Park ,  Tae Hyun Kim ,  Hyun Sook Lee ,  Hyun Chul Jang ,  Seon Hee Park

IPC分类号： G06F17/27 ,  G06F17/21 ,  G06F7/00 ,  G06F17/30 ,  G10L15/00

CPC分类号： G06Q50/22 ,  G06F19/00 ,  Y10S707/99933 ,  Y10S707/99943

摘要： The present invention relates to an apparatus and method for recognizing biological named entity from biological literature based on united medical language system (UMLS). The apparatus and the method receives metathesaurus from the UMLS, constructs a concept name database, a single name database and a category keyterm database, which are language resources to be used recognize a named entity, receives each concept name stored in the concept name database, extracts features of each of the concept names by using data stored in the single name database and the category keyterm database, constructs a rule database by creating rules used to recognize the named entity and filtering the rules by using the extracted features, receives a biological literature, extracts nouns and noun phrases that are candidate named entities, applies the rules stored in the rule database to the nouns and the noun phrases, and recognizes the named entities. In the present invention, the biological named entities can be effectively extracted which can be used as important information individual in input literature.

摘要翻译： 本发明涉及一种基于联合医学语言系统（UMLS）从生物文献识别生物命名实体的装置和方法。 该装置和方法从UMLS接收metathesaurus，构建一个概念名称数据库，一个单一名称数据库和一个类别keyterm数据库，它们是用于识别命名实体的语言资源，接收存储在概念名称数据库中的每个概念名称， 通过使用存储在单个名称数据库和类别keyterm数据库中的数据来提取每个概念名称的特征，通过创建用于识别命名实体的规则并通过使用提取的特征来过滤规则来构建规则数据库，接收生物文献 提取作为候选名称实体的名词和名词短语，将存储在规则数据库中的规则应用于名词和名词短语，并识别命名实体。 在本发明中，可以有效地提取生物名称的实体，其可以用作输入文献中个体的重要信息。

公开(公告)号：US06377653B1

公开(公告)日：2002-04-23

申请号：US09498319

申请日：2000-02-04

申请人： Sooyeul Lee ,  Hyeon-Bong Pyo ,  Seunghwan Kim ,  Seon Hee Park

发明人： Sooyeul Lee ,  Hyeon-Bong Pyo ,  Seunghwan Kim ,  Seon Hee Park

IPC分类号： G01B1502

CPC分类号： A61B6/505 ,  A61B6/583

摘要： A method for calibrating a trabecular index with a sawtooth-shaped rack which corrects an error in the trabecular index due to the characteristics of an image input device or radiographic conditions of an x-ray image when a bone mineral density is measured by setting up the trabecular index with trabecular patterns of a simple x-ray image. The present invention includes a method for calibrating the trabecular index with a sawtooth-shaped rack, wherein bone mineral density is measured with the trabecular index calculated from an x-ray image and an error in the trabecular index is calibrated by a method of calibrating the trabecular index, the method includes the following steps. A first step is preparing an x-ray image by radiographing a bone and a sawtooth-shaped rack together. A second step is attaining trabecular indexes from the x-ray image of the rack and the bone. And, a third step is calibrating the trabecular index of the bone with the trabecular index of the rack.

摘要翻译： 一种用锯齿形齿条校准小梁索引的方法，其通过图像输入装置的特征或者通过设置骨密度来测量骨密度来测量X射线图像的特征时校正小梁指数的误差 小梁指数与小梁模式的简单x射线图像。 本发明包括用锯齿形齿条校准小梁指数的方法，其中用从X射线图像计算的小梁指数测量骨矿物质密度，并且通过校准所述小梁指数的方法来校准所述小梁指数的误差 小梁指数，该方法包括以下步骤。 第一步是通过将骨头和锯齿形架架放在一起来准备X射线图像。 第二步是从架子和骨骼的x射线图像获得小梁指数。 而且，第三步是用骨架的小梁指数校正骨小梁指数。

公开(公告)号：US09019097B2

公开(公告)日：2015-04-28

申请号：US12482792

申请日：2009-06-11

申请人： Jae Hun Choi ,  Myung Eun Lim ,  Sun Lee Bang ,  Dae Hee Kim ,  Soo Jun Park ,  Seon Hee Park

发明人： Jae Hun Choi ,  Myung Eun Lim ,  Sun Lee Bang ,  Dae Hee Kim ,  Soo Jun Park ,  Seon Hee Park

IPC分类号： G08B1/08 ,  G08B23/00 ,  G08B1/00 ,  G07F9/02 ,  A61J7/00 ,  A61J7/04 ,  G06F19/00 ,  G07F11/16 ,  G07F11/62 ,  G07F17/00

CPC分类号： G07F9/026 ,  A61J7/0084 ,  A61J7/0436 ,  A61J7/0481 ,  G06F19/00 ,  G06F19/3462 ,  G07F11/16 ,  G07F11/62 ,  G07F17/0092

摘要： An apparatus and method for assisting medication are disclosed. The apparatus includes a medication box and a medication service device. The medication box includes a plurality of containers each storing a paper bag of medication, and discharges a paper bag of medication from a corresponding one of the containers using a rotational force of an electric motor, and detects whether the stored paper bag of medication is present or is discharged. The medication service device includes a situation detector detecting a status of a user based on user identification and signal strength included in a radio frequency signal, and a status of the medication box, a situation recognizer recognizing a medication situation, and a service executor generating a service for medication. The user who has to regularly take a paper bag of medication for a long time can be assisted to take an accurate dose of medication on time.

摘要翻译： 公开了一种用于辅助药物的装置和方法。 该装置包括药盒和药物服务装置。 药盒包括多个容器，每个容器都存储药袋纸袋，并且使用电动机的旋转力从相应的一个容器中排出药袋纸，并且检测存储的药物袋是否存在 或者被排出。 药物服务装置包括：状况检测器，其基于包括在射频信号中的用户识别和信号强度以及药盒的状态，识别药物状况的情况识别器以及生成 服务服务。 需要长时间定期服用纸袋的用户可以及时准确地服用药物。

公开(公告)号：US08620993B2

公开(公告)日：2013-12-31

申请号：US12505566

申请日：2009-07-20

申请人： Min Ho Kim ,  Jae Won Jang ,  Ho Youl Jung ,  Sa Kwang Song ,  Soo Jun Park ,  Seon Hee Park

发明人： Min Ho Kim ,  Jae Won Jang ,  Ho Youl Jung ,  Sa Kwang Song ,  Soo Jun Park ,  Seon Hee Park

IPC分类号： G06F15/16

CPC分类号： H04L67/125 ,  A61B5/0002 ,  G05B15/02 ,  G06F19/00 ,  G06F19/3418 ,  H04L67/22

摘要： An activity monitoring system and method are disclosed to reduce the size of an activity sensor device to reduce its power consumption and smoothly transmit activity and occupancy information from the activity sensor device and an occupancy sensor device to an activity monitoring server to monitor an individual's activity and occupancy information. The activity monitoring system includes: an activity sensor device configured to detect a physical activity of a user, classify the detected physical activity, and transmit activity classification information as a result along with user identification information; one or more occupancy sensor devices configured to receive the activity classification information and the individual's identification information from the activity sensor device, and transmit the received information along with occupancy information; and an activity monitoring server configured to manage the activity classification information, the occupancy information, and the individual's identification information received from the occupancy sensor devices.

摘要翻译： 公开了一种活动监测系统和方法，以减少活动传感器装置的尺寸以减少其功率消耗，并将活动和占用信息从活动传感器装置和占用传感器装置平滑地传送到活动监测服务器以监测个体的活动， 占用信息。 活动监视系统包括：活动传感器装置，被配置为检测用户的身体活动，对检测到的身体活动进行分类，并且随着用户识别信息一起发送活动分类信息; 一个或多个占用传感器装置，被配置为从活动传感器装置接收活动分类信息和个体的识别信息，并将所接收的信息与占有信息一起发送; 以及活动监视服务器，被配置为管理从占用传感器装置接收的活动分类信息，占用信息和个人的识别信息。

公开(公告)号：US08585013B2

公开(公告)日：2013-11-19

申请号：US12872289

申请日：2010-08-31

申请人： Kwang Hyo Chung ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

发明人： Kwang Hyo Chung ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： F16K31/08

CPC分类号： F16K99/0001 ,  F16K99/0015 ,  F16K99/0026 ,  F16K99/0034 ,  F16K99/0046 ,  F16K2099/0078

摘要： There is provided a magnetic microvalve using a metal ball and a method of manufacturing the same. A magnetic microvalve using a metal ball according to an aspect of the invention may include: an upper substrate having a microchannel serving as a passage through which a fluid moves, a fluid inlet through which the fluid flows into the microchannel, and a fluid outlet through which the fluid, having passed through the microchannel, flows out of the microchannel; a lower substrate having a trench locally provided therein; a PDMS/metal ball combination having a metal ball and PDMS surrounding the metal ball so that the metal ball is located in a central portion thereof, the PDMS/metal ball combination being inserted into the trench provided in the lower substrate; and a magnet located above the microchannel, provided in the upper substrate, and generating magnetic force.

摘要翻译： 提供了使用金属球的磁性微型阀及其制造方法。 使用根据本发明的一个方面的金属球的磁性微型阀可以包括：具有作为流体移动通道的微通道的上基板，流体流入微通道的流体入口，以及流体出口通过 已经通过微通道的流体流出微通道; 具有局部设置在其中的沟槽的下基板; 具有围绕金属球的金属球和PDMS的PDMS /金属球组合，使得金属球位于其中心部分，PDMS /金属球组合插入设置在下基板中的沟槽中; 以及设置在上基板上的微通道上方的磁体，并产生磁力。

公开(公告)号：US08440148B2

公开(公告)日：2013-05-14

申请号：US12562058

申请日：2009-09-17

申请人： Dong-Ho Shin ,  Minsuk Jeong ,  Kyu Ho Song ,  HyeYoon Kim ,  JuHyun Jeon ,  Moon Youn Jung ,  Seon Hee Park

发明人： Dong-Ho Shin ,  Minsuk Jeong ,  Kyu Ho Song ,  HyeYoon Kim ,  JuHyun Jeon ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： B01L99/00 ,  G01N21/01

CPC分类号： G01N21/645 ,  B01L3/50273 ,  B01L3/502792 ,  B01L2200/0673 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/089 ,  B01L2300/161 ,  B01L2400/043 ,  B01L2400/0475 ,  B01L2400/0688

摘要： Provided are a microfluidic device and a microfluidic analysis equipment. The microfluidic device includes guides disposed along both edges, a lower plate including a flow path defined between the guides, and a movable upper plate moved along the guides on the lower plate and having a length less than that the flow path. A fluid flow can be simply accurately controlled by adjusting a position of the movable upper plate. As a result, the fluid can sufficiently react in the detection part and the reaction part. Therefore, effective reaction and detection can be realized using only a small amount of fluid, thereby improving sensitivity. In addition, due to the improved sensitivity, a washing process for removing materials that are not consumed in the reaction can be omitted. Also, the movable upper plate can be manually moved using a user's finger.

摘要翻译： 提供了微流体装置和微流体分析设备。 微流体装置包括沿着两个边缘布置的引导件，下板包括限定在引导件之间的流路，以及沿着下板上的引导件移动并且具有小于流动路径的长度的可移动上板。 可以通过调节可动上板的位置来简单地精确地控制流体流动。 结果，流体可以在检测部分和反应部分中充分反应。 因此，仅使用少量流体即可实现有效的反应和检测，从而提高灵敏度。 此外，由于提高的灵敏度，可以省略用于除去反应中不消耗的材料的洗涤方法。 此外，可以使用用户的手指来手动移动可动上板。

公开(公告)号：US08402629B2

公开(公告)日：2013-03-26

申请号：US12635480

申请日：2009-12-10

申请人： Dae Sik Lee ,  Yong Sun Yoon ,  Moon Youn Jung ,  Seon Hee Park

发明人： Dae Sik Lee ,  Yong Sun Yoon ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： B23P25/00 ,  B22D11/126 ,  A61M5/32 ,  B05D3/12

CPC分类号： A61M37/0015 ,  A61B5/14514 ,  A61B5/685 ,  A61M2037/0053 ,  Y10T29/49885 ,  Y10T29/4998 ,  Y10T156/1062

摘要： Provided is a method of manufacturing a hollow microneedle structure. The method includes coating a hollow core having a predetermined section and being long in a lengthwise direction with a coating solution, and solidifying the coating solution to form a coating layer, depositing a metal seed layer on the coating layer, plating the seed metal layer with a metal to form a plated layer, cutting the hollow core having the plated layer at an inclination angle with respect to the lengthwise direction for form a surface inclination, and removing the hollow core and the coating layer to form a hollow microneedle structure. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. By use of the hollow core, the microneedle structure can have vertical microneedles with a uniform inner diameter.

摘要翻译： 提供一种制造中空微针结构的方法。 该方法包括用涂布溶液涂布具有预定部分并在长度方向上长的中空芯，并固化涂布溶液以形成涂层，在涂层上沉积金属籽晶层，将种子金属层与 金属以形成镀层，切割具有相对于长度方向的倾斜角度的镀层的中空芯以形成表面倾斜，并且移除中空芯和涂层以形成中空微针结构。 因此，可以制造中空微针结构以具有使疼痛最小化的直径，长度，硬度和倾斜角度。 通过使用中空芯，微针结构可以具有均匀内径的垂直微针。

公开(公告)号：US08378812B2

公开(公告)日：2013-02-19

申请号：US12484302

申请日：2009-06-15

申请人： Jae Hun Choi ,  Myung Eun Lim ,  Dae Hee Kim ,  Sun Lee Bang ,  Soo Jun Park ,  Seon Hee Park

发明人： Jae Hun Choi ,  Myung Eun Lim ,  Dae Hee Kim ,  Sun Lee Bang ,  Soo Jun Park ,  Seon Hee Park

IPC分类号： G08B1/08 ,  G08B23/00

CPC分类号： A61J7/0409 ,  A61J7/0481 ,  A61J2200/30 ,  G06F19/00 ,  G06F19/3462 ,  G06Q20/3278 ,  G07F9/026 ,  G07F11/62

摘要： An apparatus and method for assisting medication are capable of assisting medication of users who have to regularly take medications in daily life. The apparatus includes a medication box having a plurality of containers, each of which stores a dose of medication to be taken at one time according to a medication schedule, a radio frequency (RF) transmitter carried on a user and transmitting an RF signal, an RF receiver receiving the RF signal from the RF transmitter, and a controller controlling medication assisting. Thus, the apparatus checks a spatial-temporal situation of the user, i.e. an medication, notification or information situation, using the received RF signal, and creating and providing medication service corresponding to the checked situation.

摘要翻译： 用于辅助药物的装置和方法能够帮助必须在日常生活中定期服用药物的使用者的药物。 该装置包括具有多个容器的药盒，每个容器根据药物计划一次存储一次剂量的药物，在用户身上携带的射频（RF）发射器，并发射RF信号， RF接收器从RF发射器接收RF信号，以及控制药物辅助的控制器。 因此，该装置使用接收到的RF信号来检查用户的时空情况，即药物，通知或信息情况，以及创建和提供与检查情况相对应的药物服务。