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    Microfluidic device and microfluidic analysis equipment
    2.
    发明授权
    Microfluidic device and microfluidic analysis equipment 有权
    微流控装置和微流体分析设备

    公开(公告)号：US08440148B2

    公开(公告)日：2013-05-14

    申请号：US12562058

    申请日：2009-09-17

    申请人： Dong-Ho Shin ,  Minsuk Jeong ,  Kyu Ho Song ,  HyeYoon Kim ,  JuHyun Jeon ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Dong-Ho Shin ,  Minsuk Jeong ,  Kyu Ho Song ,  HyeYoon Kim ,  JuHyun Jeon ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： B01L99/00 ,  G01N21/01

    CPC分类号： G01N21/645 ,  B01L3/50273 ,  B01L3/502792 ,  B01L2200/0673 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/089 ,  B01L2300/161 ,  B01L2400/043 ,  B01L2400/0475 ,  B01L2400/0688

    摘要： Provided are a microfluidic device and a microfluidic analysis equipment. The microfluidic device includes guides disposed along both edges, a lower plate including a flow path defined between the guides, and a movable upper plate moved along the guides on the lower plate and having a length less than that the flow path. A fluid flow can be simply accurately controlled by adjusting a position of the movable upper plate. As a result, the fluid can sufficiently react in the detection part and the reaction part. Therefore, effective reaction and detection can be realized using only a small amount of fluid, thereby improving sensitivity. In addition, due to the improved sensitivity, a washing process for removing materials that are not consumed in the reaction can be omitted. Also, the movable upper plate can be manually moved using a user's finger.

    摘要翻译： 提供了微流体装置和微流体分析设备。 微流体装置包括沿着两个边缘布置的引导件，下板包括限定在引导件之间的流路，以及沿着下板上的引导件移动并且具有小于流动路径的长度的可移动上板。 可以通过调节可动上板的位置来简单地精确地控制流体流动。 结果，流体可以在检测部分和反应部分中充分反应。 因此，仅使用少量流体即可实现有效的反应和检测，从而提高灵敏度。 此外，由于提高的灵敏度，可以省略用于除去反应中不消耗的材料的洗涤方法。 此外，可以使用用户的手指来手动移动可动上板。

    MICROFLUIDIC DILUTION DEVICE
    3.
    发明申请
    MICROFLUIDIC DILUTION DEVICE 审中-公开
    微流体稀释装置

    公开(公告)号：US20100159573A1

    公开(公告)日：2010-06-24

    申请号：US12534012

    申请日：2009-07-31

    申请人： Kwang Hyo CHUNG ,  JuHyun Jeon ,  Dae-Sik Lee ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Kwang Hyo CHUNG ,  JuHyun Jeon ,  Dae-Sik Lee ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： C12M1/00 ,  B01L3/00 ,  G01N33/48

    CPC分类号： G01N1/38

    摘要： Provided is a microfluidic dilution device that uses capillary force to dilute first and second fluids in a predetermined ratio. The microfluidic dilution device includes a channel plate, a cover plate, fluid chambers, and a confluence chamber. The fluid chambers are filled with first and second fluids in a predetermined ratio. First and second fluids flowing to the confluence chamber are diluted in a predetermined ratio.

    摘要翻译： 提供了使用毛细管力以预定比例稀释第一和第二流体的微流体稀释装置。 微流体稀释装置包括通道板，盖板，流体室和汇合室。 流体室以预定比例填充有第一和第二流体。 流入合流室的第一和第二流体以预定比例稀释。

    PS-SPCL SEARCHING APPARATUS AND METHOD USING SURFACE PLASMON RESONANCE
    6.
    发明申请
    PS-SPCL SEARCHING APPARATUS AND METHOD USING SURFACE PLASMON RESONANCE 审中-公开
    PS-SPCL搜索设备和使用表面等离子体共振的方法

    公开(公告)号：US20100267570A1

    公开(公告)日：2010-10-21

    申请号：US12746992

    申请日：2008-04-17

    申请人： Yo Han Choi ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Yo Han Choi ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： C40B30/00 ,  C40B60/12

    CPC分类号： G01N33/54373 ,  C40B30/00 ,  G01N21/553

    摘要： A Positional Scanning—Synthetic Peptide Combinatorial Library (PS-SPC) searching apparatus and method using Surface Plasmon Resonance (SPR) are provided. The method includes spotting and fixing each of a plurality of peptide pools to a top of one thin metal film, inputting specific materials to the top of the thin metal film, applying a TM-mode light to a bottom of the thin metal film and exciting SPR for the thin metal film, and detecting a TM mode reflected light reflected from the thin metal film and displaying the detected light as a two-dimensional image.

    摘要翻译： 提供了使用表面等离子体共振（SPR）的位置扫描合成肽组合库（PS-SPC）搜索装置和方法。 该方法包括将多个肽池中的每一个点样并固定到一个薄金属膜的顶部，将特定材料输入到金属薄膜的顶部，向薄金属膜的底部施加TM模式的光，并激发 SPR，并且检测从薄金属膜反射的TM模式反射光，并将检测到的光显示为二维图像。

    Portable digital reader for urinalysis
    7.
    发明授权
    Portable digital reader for urinalysis 有权
    便携式数字读取器用于尿液分析

    公开(公告)号：US08991238B2

    公开(公告)日：2015-03-31

    申请号：US13390596

    申请日：2010-03-05

    申请人： Dae Sik Lee ,  Hyun Woo Song ,  Byoung Goo Jeon ,  Min Joon Kim ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Dae Sik Lee ,  Hyun Woo Song ,  Byoung Goo Jeon ,  Min Joon Kim ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： G01N21/00 ,  G01N33/493 ,  G01N21/84 ,  G01N15/06

    CPC分类号： G01N33/493 ,  G01N15/06 ,  G01N21/8483 ,  G01N2201/0221

    摘要： The present invention relates to a portable digital reader for urinalysis. The portable digital reader for reading an analysis target chip including a plurality of test areas, comprises: a main body including a light emitting section having light emitting elements for radiating light, an integral optical splitter for uniformly distributing the light from the light emitting section to each test area of the analysis target chip, a light receiving section for receiving light reflected from the each test area so as to convert the same to electric signals, and a measuring section for measuring concentration according to the electric signals obtained from the light receiving section; a main supporting body having the analysis target chip and assembled with the main body; and an auxiliary supporting body assembled between the analysis target chip and the main supporting body, including a groove for assembling the analysis target chip, and assembled with the main supporting body to be exchanged after use. Therefore, it is possible to prevent the reader from being contaminated with superfluous urine by forming a portion contacting a strip chip to be exchangeable and disposing a moisture absorption material to a portion for introducing the strip chip.

    摘要翻译： 本发明涉及用于尿分析的便携式数字读取器。 用于读取包括多个测试区域的分析目标芯片的便携式数字读取器包括：主体，包括具有用于发光的发光元件的发光部分，用于将来自发光部分的光均匀分布的整体光分路器 分析目标芯片的每个测试区域，用于接收从每个测试区域反射的光以将其转换为电信号的光接收部分;以及根据从光接收部分获得的电信号来测量浓度的测量部分 ; 具有分析目标芯片并与主体组装的主支撑体; 以及组装在分析对象芯片和主支撑体之间的辅助支撑体，包括用于组装分析对象芯片的凹槽，并且与使用后要更换的主支撑体组装在一起。 因此，可以通过形成与条形芯片接触的部分来防止读取器被多余的尿污染，并且将吸湿材料设置在引导带状芯片的部分。

    PORTABLE DIGITAL READER FOR URINALYSIS
    8.
    发明申请
    PORTABLE DIGITAL READER FOR URINALYSIS 有权
    便携式数字读数器

    公开(公告)号：US20120152002A1

    公开(公告)日：2012-06-21

    申请号：US13390596

    申请日：2010-03-05

    申请人： Dae Sik Lee ,  Hyun Woo Song ,  Byoung Goo Jeon ,  Min Joon Kim ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Dae Sik Lee ,  Hyun Woo Song ,  Byoung Goo Jeon ,  Min Joon Kim ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： G01N21/00

    CPC分类号： G01N33/493 ,  G01N15/06 ,  G01N21/8483 ,  G01N2201/0221

    摘要： The present invention relates to a portable digital reader for urinalysis. The portable digital reader for reading an analysis target chip including a plurality of test areas, comprises: a main body including a light emitting section having light emitting elements for radiating light, an integral optical splitter for uniformly distributing the light from the light emitting section to each test area of the analysis target chip, a light receiving section for receiving light reflected from the each test area so as to convert the same to electric signals, and a measuring section for measuring concentration according to the electric signals obtained from the light receiving section; a main supporting body having the analysis target chip and assembled with the main body; and an auxiliary supporting body assembled between the analysis target chip and the main supporting body, including a groove for assembling the analysis target chip, and assembled with the main supporting body to be exchanged after use. Therefore, it is possible to prevent the reader from being contaminated with superfluous urine by forming a portion contacting a strip chip to be exchangeable and disposing a moisture absorption material to a portion for introducing the strip chip.

    摘要翻译： 本发明涉及用于尿分析的便携式数字读取器。 用于读取包括多个测试区域的分析目标芯片的便携式数字读取器包括：主体，包括具有用于发光的发光元件的发光部分，用于将来自发光部分的光均匀分布的整体光分路器 分析目标芯片的每个测试区域，用于接收从每个测试区域反射的光以将其转换为电信号的光接收部分;以及根据从光接收部分获得的电信号来测量浓度的测量部分 ; 具有分析目标芯片并与主体组装的主支撑体; 以及组装在分析对象芯片和主支撑体之间的辅助支撑体，包括用于组装分析对象芯片的凹槽，并且与使用后要更换的主支撑体组装在一起。 因此，可以通过形成与条形芯片接触的部分来防止读取器被多余的尿污染，并且将吸湿材料设置在引导带状芯片的部分。

    Method of manufacturing hollow microneedle structures
    9.
    发明授权
    Method of manufacturing hollow microneedle structures 有权
    制造中空微针结构的方法

    公开(公告)号：US08202434B2

    公开(公告)日：2012-06-19

    申请号：US12621594

    申请日：2009-11-19

    申请人： Dae Sik Lee ,  Hyun Woo Song ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Dae Sik Lee ,  Hyun Woo Song ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： B44C1/22

    CPC分类号： A61M37/0015 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C33/3842 ,  B29L2031/7544 ,  B29L2031/756 ,  B81B2201/055 ,  B81C1/00111

    摘要： Provided is a method of manufacturing a hollow microneedle structure. The method includes forming an injection mold having a through hole, filling the injection mold with a photoresist formed of a viscous material, and extruding the photoresist from the injection mold through the through hole, solidifying the extruded photoresist to form a needle-type photoresist structure, forming a seed layer on the surface of the photoresist structure, forming a metal plated layer on the seed layer, inclining an end tip of the photoresist structure having the metal plated layer, and removing the photoresist from the metal plated layer to form a hollow. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. The hollow microneedle structure can be combined with an apparatus for detecting a biomaterial or injecting cosmetic substances or medicines, and variously applied.

    摘要翻译： 提供一种制造中空微针结构的方法。 该方法包括形成具有通孔的注射模具，用由粘性材料形成的光致抗蚀剂填充注射模具，并且通过通孔从注射模具中挤出光致抗蚀剂，固化挤出的光致抗蚀剂以形成针型光致抗蚀剂结构 在光致抗蚀剂结构的表面上形成种子层，在种子层上形成金属镀层，使具有金属镀层的光致抗蚀剂结构的末端倾斜，从金属镀层除去光致抗蚀剂，形成中空 。 因此，可以制造中空微针结构以具有使疼痛最小化的直径，长度，硬度和倾斜角度。 中空微针结构可以与用于检测生物材料或注射化妆品物质或药物的装置组合，并进行各种应用。