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公开(公告)号：US20210179598A1
公开(公告)日：2021-06-17
申请号：US17046996
申请日：2019-04-12
Inventor： Honglin LI , Yufang XU , Zhenjiang ZHAO , Lili ZHU
IPC: C07D413/10 , C07D401/14 , C07D405/14 , C07D213/73 , C07D401/04 , C07D401/10 , C07D487/04 , C07D471/04 , C07D401/12 , C07D417/04
Abstract: Provided is a selective JAK2 inhibitor and application thereof. In particular, it relates to the compound of the following Formula (I), and the use of the compound in the treatment of JAK2-mediated related diseases and in the preparation of the medicament for treating JAK2-mediated related diseases.
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62.发明授权公开(公告)号：US10598585B2
公开(公告)日：2020-03-24
申请号：US15324552
申请日：2015-06-15
Inventor： Hualin Wang , Yuan Huang , Yang Qiu , Pengbo Fu , Yanhong Zhang , Zhishan Bai , Qiang Yang , Fengqin He
Abstract: A method and a device for synchronous high-speed photographing of microparticle rotation in a liquid cyclone field and for determining the rotation velocity of a microparticle in a liquid cyclone field by using a combination of a synchronous high-speed photographing system and a transparent microparticle containing two centrosymmetrically arranged inner cores having the same diameter. The method comprises: using a transparent microparticle comprising two inner cores having the same diameter and arranged centrosymmetrically as a rotation test particle; acquiring synchronously two groups of two dimensional image series of microparticle motion in a liquid cyclone field using two orthogonally arranged high-speed digital cameras; and reconstructing a three dimensional motion trajectory of the microparticle from the two groups of synchronous image series, and determining a rotation velocity of the microparticle in the cyclone field at the same time.
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公开(公告)号：US10301516B2
公开(公告)日：2019-05-28
申请号：US15327920
申请日：2015-07-20
Applicant: KUNSHAN TIANYANG HOT MELT ADHESIVE CO., LTD. , SHANGHAI TIANYANG HOT MELT ADHESIVE CO., LTD. , EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventor： Zhelong Li , Wanyu Zhu , Heji Lei , Fangqun Wu , Zuoxiang Zeng
IPC: C09J167/02 , C09J11/06 , C08G63/672
Abstract: A method for preparation of a high-viscosity polyester hot-melt adhesive with a partially sensitive viscosity-temperature property is disclosed, including the steps of: i) subjecting terephthalic acid, isophthalic acid, dodecanedioic acid, adipic acid, butanediol, dipropylene glycol and hexanediol to an esterification reaction in the presence of tetrabutyl titanate serving as a catalyst; and ii) adding an antioxidant to a product resulting from step i) to conduct a polycondensation reaction under a reduced pressure so as to obtain the high-viscosity polyester hot-melt adhesive which has a low melting point of 130° C.-135° C. and a partially sensitive viscosity-temperature property.
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公开(公告)号：US10203536B2
公开(公告)日：2019-02-12
申请号：US15316429
申请日：2014-06-05
Inventor： Zhigang Zheng
IPC: C09K19/00 , G02F1/1333 , C09K19/52 , C09K19/54 , C09K19/58 , C09K19/60 , G02F1/137 , C09B31/12 , C09K11/06 , G02F1/1334
Abstract: A photo-tunable liquid crystal composition may include a polymer matrix and a liquid crystal mixture dispersed within the polymer matrix. The liquid crystal mixture may include at least one achiral nematic liquid crystal material, at least sine photo-active chiral dopant, at least one photo-inactive chiral dopant, and at least one emissive dye. The composition may be fabricated in the form of an emulsion, a wet film, or a dry film. The dry film may be used in a photo-tunable liquid crystal film laser. The output wavelength of the photo-tunable liquid crystal film laser may be tuned by exposing the dry film to illumination having at least one wavelength at one or more transition wavelengths.
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公开(公告)号：US10184126B2
公开(公告)日：2019-01-22
申请号：US14419106
申请日：2013-08-01
Inventor： Yi Yang , Xianjun Chen , Zhengcai Ma , Renmei Liu
Abstract: Provided is an optically controlled gene expression system of prokaryotic bacterium, comprising: a) a photosensitive recombinant transcription factor encoding gene, the photosensitive recombinant transcription factor is one fusion protein comprising a first polypeptide as the DNA bonding domain and a second polypeptide as the photosensitive domain; b) a target transcription unit comprising promoter or promoter-reaction element or reaction element-promoter containing at least one reaction element recognized/bound by the first polypeptide and the nucleic acid sequence to be transcribed. Also provided is a prokaryotic expression vector comprising said optically controlled gene expression system, and a method for regulating gene expression in a prokaryotic host cell by using the optically controlled gene expression system. Also provided is a reagent kit containing different components of the optically controlled gene expression system. The optically controlled gene expression system of prokaryotic bacterium has a quick, effective and powerful induction, is safer than other inducers, is of little or no toxicity, and can control gene expression both spatially and temporally, and can regulate many life processes of prokaryotic bacterium.
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Patent Agency Ranking
公开(公告)号：US10000448B2
公开(公告)日：2018-06-19
申请号：US15124397
申请日：2014-03-13
Inventor： Zhenshan Hou , Ran Zhang
CPC classification number: C07C269/04 , B01J21/00 , B01J23/10 , B01J23/14 , B01J23/34 , B01J23/83 , B01J23/92 , B01J23/94 , B01J2523/31 , B01J2523/3712 , B01J2523/60 , Y02P20/584 , C07C271/12
Abstract: Methods, systems and kits for preparing carbamates as well as catalysts for preparing the carbamates, are disclosed. The methods for preparing carbamate can include providing a catalyst comprising cerium oxide (CeO2) and at least one metal selected from the group consisting of iron (Fe), manganese (Mn), titanium (Ti), cobalt (Co), aluminum (Al), zinc (Zn), calcium (Ca), tin (Sn), indium (In), and any combination thereof; contacting the catalyst with at least one amine and at least one alcohol to form a mixture; and contacting the mixture with carbon dioxide under conditions sufficient to form the carbamate.
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公开(公告)号：US20180007898A1
公开(公告)日：2018-01-11
申请号：US15534906
申请日：2014-11-17
Inventor： Xiaping ZHOU
CPC classification number: A01N43/16 , A01N25/26 , A01N37/34 , A01N37/38 , A01N47/14 , A01N47/18 , A01N47/22 , A01N57/14 , A01N59/16 , A01N59/20
Abstract: Biopesticide compositions, and methods and kits for their preparation from lignin are disclosed. A biopesticide may include a modified lignin chelated with one or more pesticides, the one or more pesticides having at least one acidic pesticide. The modified lignin may have one or more functional groups. Methods of producing a biopesticide may include obtaining a lignin, contacting the lignin with one or more bacteria under conditions suitable for producing a modified lignin, and chelating the modified lignin with one or more pesticides, the one or more pesticides having at least one acidic pesticide.
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68.发明授权公开(公告)号：US09611339B2
公开(公告)日：2017-04-04
申请号：US14394269
申请日：2013-04-15
Inventor： Ning Zhao , Ruihua Cheng , Xuelian He , Zhen Liu , Boping Liu
IPC: C08F10/02
CPC classification number: C08F10/02 , C08F2410/04 , Y02P20/52 , C08F210/16 , C08F210/14 , C08F4/69 , C08F4/68
Abstract: The present invention relates to a carriered hybrid vanadium-chromium-based catalyst, characterized in the catalyst is carriered on a porous inorganic carrier and a V active site and an organic Cr active site are present on the porous inorganic carrier at the same time. The present invention further relates to a process for producing a carriered hybrid vanadium-chromium-based catalyst. The catalyst of the present invention can be used for producing ethylene homopolymers and ethylene/α-olefin copolymers. The hybrid vanadium-chromium-based catalyst can have high activity and produce polyethylene polymers having the properties of broad molecular weight distribution (Part of the products are bimodal distribution) and excellent α-olefin copolymerization characteristic.
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公开(公告)号：US20170088535A1
公开(公告)日：2017-03-30
申请号：US15310760
申请日：2014-05-14
Inventor： Zhenshan HOU , Baoning SONG
CPC classification number: C07D317/36 , B01J31/0239 , B01J31/0254 , B01J31/08 , B01J31/26 , B01J31/4007 , B01J31/4084 , B01J37/0036 , B01J37/04 , B01J38/00 , B01J38/48 , B01J2231/341 , C07D303/04 , C07D303/08 , C07D317/12
Abstract: Catalysts and methods for making cyclic carbonates are disclosed. The catalyst may include at least one polymer quaternary ammonium salt, at least one metal halide and silica gel. The method of making the cyclic carbonates may include forming a mixture that includes the catalyst and an epoxide, and contacting the mixture with carbon dioxide in a reactor under conditions to form the propylene carbonate.
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公开(公告)号：US09493351B2
公开(公告)日：2016-11-15
申请号：US13811835
申请日：2011-12-07
Applicant: Xinhua Zhong , Wenjin Zhang
Inventor： Xinhua Zhong , Wenjin Zhang
CPC classification number: C01B19/007 , C30B9/08 , C30B29/46 , C30B29/62
Abstract: Methods for the non-hot-injection synthesis of semiconductor nanocrystals are described. For example, a multi-podal cadmium selenide nanocrystal may be produced by a method including heating a degassed mixture comprising cadmium oxide, selenium, trioctylphosphine, and a carboxylic acid in a non-coordinating solvent from about room temperature to about 210° C., where the multi-podal cadmium selenide nanocrystal may be a tetrapodal cadmium selenide nanocrystal.
Abstract translation: 描述了非热注射合成半导体纳米晶体的方法。 例如，可以通过包括在约室温至约210℃的非配位溶剂中加热包含氧化镉，硒，三辛基膦和羧酸的脱气混合物的方法来制备多镉硒化镉纳米晶体， 其中多镉硒化镉纳米晶体可以是四节省硒化镉纳米晶体。
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