公开(公告)号：US09272279B2

公开(公告)日：2016-03-01

申请号：US13468258

申请日：2012-05-10

Applicant: Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

Inventor： Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

IPC: G01N21/75 ,  B01L3/00 ,  G01N33/543 ,  G01N33/569 ,  B01J20/28

CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract translation: 本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。 该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许 降低这种液体的起始体积。 优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。 分配器和支撑件保持在一起以在膜周围形成一个信封。 在这样做时优选使用铰链，夹子和其它这样的装置。

公开(公告)号：US09217048B2

公开(公告)日：2015-12-22

申请号：US14183791

申请日：2014-02-19

Applicant: EMD Millipore Corporation

Inventor： Jad Jaber ,  Wilson Moya ,  James Hamzik ,  Arezki Boudif ,  Yu Zhang ,  Neil Soice ,  John Charkoudian ,  Nripen Singh

IPC: C08F126/00 ,  C08F126/02 ,  C07K1/30 ,  C07K1/32 ,  C08F8/00 ,  C08F8/02 ,  C07K16/00

CPC classification number: B01J41/14 ,  B01J41/13 ,  C07K1/30 ,  C07K1/32 ,  C07K16/00 ,  C07K2317/10 ,  C08F8/00 ,  C08F8/02 ,  C08F126/02 ,  C08F26/02

Abstract: The present invention provides novel and improved stimulus responsive polymers and methods of using the same for the purification of biomolecules.

Abstract translation: 本发明提供了新的和改进的刺激响应聚合物及其用于生物分子纯化的方法。

公开(公告)号：US09205955B2

公开(公告)日：2015-12-08

申请号：US13153804

申请日：2011-06-06

Applicant: Sebastien Cirou ,  Rene Reinbigler ,  Virginie Buisson ,  Jean-Louis Weissenbach

Inventor： Sebastien Cirou ,  Rene Reinbigler ,  Virginie Buisson ,  Jean-Louis Weissenbach

IPC: B65D33/00 ,  A61M1/36 ,  B01D61/18 ,  B01D61/20 ,  F04B43/08

CPC classification number: B65D33/00 ,  A61M1/36 ,  A61M2205/125 ,  A61M2209/088 ,  B01D61/18 ,  B01D61/20 ,  B01D2313/105 ,  B01D2313/125 ,  B01D2313/58 ,  F04B43/08

Abstract: The invention concerns a device comprising a base; a circuit comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed upright on a front face (5) of said base (2) and a second shell (17) mounted on said first shell (16), said first shell (16) and second shell (17) clamping said bag to form conduits; said bag comprising first through apertures on one side and said first shell (16) comprising hooking studs (106) on an upper part, which studs (106) pass through said first apertures.

Abstract translation: 本发明涉及一种包括基底的装置; 包括包括两个柔性膜和传送网络连接器的袋子的电路以及包括垂直设置在所述基座（2）的前面（5）上的第一壳体（16）和第二壳体（17）的压力机（9） 在所述第一壳体（16）上，所述第一壳体（16）和第二壳体（17）夹紧所述袋以形成导管; 所述袋包括在一侧上的第一通孔，所述第一壳体（16）包括在上部上的钩形螺柱（106），所述螺柱（106）穿过所述第一孔。

公开(公告)号：US09187240B2

公开(公告)日：2015-11-17

申请号：US14191499

申请日：2014-02-27

Applicant: EMD Millipore Corporation

Inventor： James Hobson ,  James Austin ,  Boris Pesakovich ,  Elias G. Noukas ,  Thomas Janko ,  Shaun McMahon

IPC: B65D5/36 ,  B65D3/00 ,  F16L3/08 ,  B65B67/12 ,  B65F1/06 ,  B65D88/20 ,  B65B69/00 ,  B65D90/04

CPC classification number: A61J1/10 ,  B65B69/0091 ,  B65D88/20 ,  B65D90/046 ,  B65D2203/10 ,  B65D2303/00 ,  B65F1/06 ,  Y10T29/49826

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract translation: 本发明是一种用于包含一个或多个端口的袋的对准装置。 对准装置附接到一个或多个端口或邻近一个或多个端口的袋。 该板具有指示器或独特的外边缘形状，其被设计成装配在保持器中相应的独特开口中，以确保袋和其端口在保持器中的适当对准。 板具有与袋的一个或多个端口相等并且对准的一系列孔，并且该端口延伸穿过板的孔。

公开(公告)号：US09043032B2

公开(公告)日：2015-05-26

申请号：US12739484

申请日：2008-11-20

Applicant: Christophe Paragot ,  Stephane Lemaire

Inventor： Christophe Paragot ,  Stephane Lemaire

IPC: G06F3/048 ,  H04L29/08 ,  G06Q50/22 ,  H04L12/58

CPC classification number: H04L67/025 ,  C02F2209/006 ,  C02F2209/008 ,  G06Q50/22 ,  H04L51/00 ,  H04L67/02 ,  H04L67/12 ,  H04L67/125 ,  H04L67/34

Abstract: A verification and control method for at least one water purification system is described, which includes a step of supplying, by a server embedded with the water purification system, an editing interface comprising a zone for selecting items of exploitation information representing physical quantities associated with the water purification system, a step of selecting, via the first remote browser, at least one item of exploitation information to constitute at least one exploitation interface page, a step of sending a request to access the exploitation page, by a second remote browser, to the server, a step of collecting the value of each physical quantity represented by a selected item of information to constitute the page, and a step of supplying, by the server, the page comprising each collected value.

Abstract translation: 描述了用于至少一个水净化系统的验证和控制方法，其包括由嵌入了水净化系统的服务器提供编辑界面的编辑界面，该编辑界面包括用于选择表示与 水净化系统，通过第一远程浏览器选择至少一个利用信息项以构成至少一个利用界面页面的步骤，通过第二远程浏览器发送访问开发页面的请求的步骤 服务器，收集由所选择的信息项表示的每个物理量的值以构成页面的步骤，以及由服务器提供包括每个收集的值的页面的步骤。

公开(公告)号：US09010545B2

公开(公告)日：2015-04-21

申请号：US13312491

申请日：2011-12-06

Applicant: Gabriel Tkacik ,  Philip Goddard ,  Willem Kools ,  Nitin Satav

Inventor： Gabriel Tkacik ,  Philip Goddard ,  Willem Kools ,  Nitin Satav

IPC: C07K1/34 ,  B01D71/34 ,  B01D61/14 ,  B01D67/00 ,  B01D69/12

CPC classification number: B01D69/12 ,  B01D61/145 ,  B01D67/0013 ,  B01D67/0016 ,  B01D67/0018 ,  B01D71/34 ,  B01D71/68 ,  B01D2323/12 ,  B01D2323/42 ,  B01D2325/022 ,  C07K1/34

Abstract: The present invention is an integral multilayered composite membrane having at least one ultrafiltration layer made by cocasting or sequentially casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a multilayered composite membrane having at least one ultrafiltration layer.

公开(公告)号：US08921096B2

公开(公告)日：2014-12-30

申请号：US13187698

申请日：2011-07-21

Applicant: Jean-Louis Weissenbach ,  Rene Reinbigler ,  Virginie Buisson ,  Christine Abouayad El Idrissi ,  Sebastien Cirou

Inventor： Jean-Louis Weissenbach ,  Rene Reinbigler ,  Virginie Buisson ,  Christine Abouayad El Idrissi ,  Sebastien Cirou

IPC: B01D15/14 ,  B01D65/00 ,  B62B1/00 ,  B62B5/00 ,  F04B23/00 ,  F04B53/22 ,  C12M1/12 ,  C12M1/34 ,  G01G19/02 ,  F04B17/06 ,  B01L9/00

CPC classification number: F04B17/06 ,  B01D65/00 ,  B01L9/54 ,  B62B5/00 ,  C12M1/12 ,  C12M29/00 ,  F04B23/00 ,  F04B53/22 ,  Y10T137/6851

Abstract: The invention concerns a pump cart for a biological liquid treatment installation, having a first lateral face (40), and a second lateral face (41) by which it is configured to be juxtaposed against a conveying network cart (1) of the installation and a front face (42) meeting the lateral faces (40, 41), and comprising at least one pump (414), a pump support (50) on which is mounted said pump (414), and a guide member for making said pump (414) movable in translation and on which said support (50) is mounted; said support (50) being movable in translation in a direction going from the first lateral face (40) towards the second lateral face (41); whereby said pump (414) is disposed at a predetermined location on said cart (2) depending on the type of treatment carried out.

Abstract translation: 本发明涉及一种用于生物液体处理装置的泵车，其具有第一侧面（40）和第二侧面（41），通过所述第二侧面（41），所述第一侧面（41）被构造成与所述装置的输送网络推车（1）并置， 与所述侧面（40,41）接合的前表面（42），并且包括至少一个泵（414），在其上安装有所述泵（414）的泵支撑件（50），以及用于使所述泵 （414），其可移动地平移并且其上安装有所述支撑件（50）; 所述支撑件（50）能够在从所述第一侧面（40）朝向所述第二侧面（41）的方向上平移移动; 由此所述泵（414）根据执行的处理类型而设置在所述推车（2）上的预定位置处。

公开(公告)号：US08916045B2

公开(公告)日：2014-12-23

申请号：US13430734

申请日：2012-03-27

Applicant: Rene Reinbigler ,  Jean-Louis Weissenbach ,  Cecile Delbos

Inventor： Rene Reinbigler ,  Jean-Louis Weissenbach ,  Cecile Delbos

IPC: B01D35/00 ,  B01D29/52 ,  C12M1/00 ,  C12M3/00 ,  B01D29/00

CPC classification number: C12M47/12 ,  C12M23/44

Abstract: The invention concerns an installation for treating biological liquid comprising a platform provided with an edge running front-to-back, a pump (105), a filtration assembly (111, 150), a pre-filtration assembly (114) having an inlet point and an outlet point respectively belonging to first and second T-shaped branching connectors (137, 156), two pre-filtration components (115a, 115b) aligned in a front-to-back direction on said platform along said front-to-back edge and each provided with inlet (157, 158) and outlet (159, 151) nozzles, said installation comprising first and second conduits (152, 153) connected to said first T-shaped connector and respectively to said inlet nozzles and third and fourth conduits (154, 155) connected to said second T-shaped connector and respectively to said outlet nozzles (159, 151), which inlet and outlet nozzles and conduits are on an opposite side of said pre-filtration components (105) to said front-to-back edge of said platform.

Abstract translation: 本发明涉及一种用于处理生物液体的装置，包括设置有前后运行的边缘的平台，泵（105），过滤组件（111,150），具有入口点的预过滤组件（114） 和分别属于第一和第二T形分支连接器（137,156）的出口点，沿着所述前后方向在所述平台上沿前后方向排列的两个预过滤部件（115a，115b） 边缘，每个具有入口（157,158）和出口（159,151）喷嘴，所述装置包括连接到所述第一T形连接器并分别连接到所述入口喷嘴的第一和第二导管（152,153），以及第三和第四 连接到所述第二T形连接器并且分别连接到所述出口喷嘴（159,151）的导管（154,155），所述入口喷嘴和出口喷嘴和导管在所述预过滤部件（105）的相对侧与所述前部 所述平台的后边缘。

公开(公告)号：US08883003B2

公开(公告)日：2014-11-11

申请号：US13950646

申请日：2013-07-25

Applicant: EMD Millipore Corporation

Inventor： Sebastien Cirou ,  Jean-Louis Weissenbach ,  Rene Reinbigler ,  Jean-Luc Beulay ,  Frans Mels ,  Cecile Delbos

IPC: B01D25/19 ,  B01D25/21 ,  B01D25/12 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08

CPC classification number: B23P19/04 ,  B01D25/127 ,  B01D25/14 ,  B01D25/164 ,  B01D25/19 ,  B01D61/18 ,  B01D61/20 ,  B01D63/082 ,  B01D2313/02 ,  B01D2313/06 ,  B01D2313/105 ,  B01D2313/125 ,  Y10T29/49826

Abstract: The invention concerns a filtration device comprising a manifold (3) providing fluid connection and mechanical connection comprising a clamping plate (4) movably mounted relative to the manifold (3) and adapted to compress at least one cassette (2) against the manifold (3), means for driving and guiding the clamping plate comprising a rod (6) extending between the manifold (3) and the plate (4), an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold (3), and the member carrying the rod (6) and driving the plate (4) via the rod (6) to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

Abstract translation: 本发明涉及一种过滤装置，其包括提供流体连接的歧管（3）和包括相对于歧管（3）可移动地安装并适于将至少一个盒（2）压靠在歧管（3）上的夹板 ），用于驱动和引导夹持板的装置，其包括在歧管（3）和板（4）之间延伸的杆（6），致动器，其设置有主体和相对于主体可移动的构件，该构件适于 在延伸位置和缩回位置之间移动预定行程，主体由歧管（3）承载，并且承载杆（6）并且通过杆（6）驱动板（4）的构件被夹紧 其中构件处于其相对于其延伸位置移动经过比预定行程更短的行程的中间缩回位置的位置。

公开(公告)号：US08858792B2

公开(公告)日：2014-10-14

申请号：US12718609

申请日：2010-03-05

Applicant: Yuanpang Samuel Ding ,  Ying-Cheng Lo ,  Joshua James Miller ,  Justin Rohde ,  Sujatha Karoor ,  Stephane Dupont

Inventor： Yuanpang Samuel Ding ,  Ying-Cheng Lo ,  Joshua James Miller ,  Justin Rohde ,  Sujatha Karoor ,  Stephane Dupont

IPC: B01D61/26 ,  B01D61/44 ,  B01D61/48 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28

CPC classification number: A61M1/1696 ,  A61M1/1674 ,  A61M1/28 ,  A61M1/284 ,  A61M1/287 ,  A61M2202/0014 ,  B01D61/243 ,  B01D61/44 ,  B01D61/58

Abstract: Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source and an electrodeionization unit. The carbon source and urease source can be in the form of removable cartridges.

Abstract translation: 提供了具有集成的电去离子能力的用于血液透析或腹膜透析的系统和方法。 在一个实施方案中，透析系统包括碳源，脲酶源和电去离子单元。 碳源和脲酶源可以是可移除的盒的形式。