摘要:
Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.
摘要:
A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.
摘要翻译:一种治疗伤口的方法和用于伤口护理管理的敷料,其包括由选自由P 2 O 5,SiO 2和B 2 O 3组成的组中的一种或多种玻璃形成剂的三维玻璃基纤维体; 纤维的至少约25重量%具有在约200nm至约4000nm之间的直径,以及至少约10的长宽宽比。在另一种形式中,所述玻璃呈软膏或 奶油适用于伤口。 在其它形式中,玻璃被用作形成用于封闭伤口的缝合线的纤维,或者作为封闭伤口的手术胶中的颗粒。
摘要:
An apparatus for promoting granulation and epithelialisation at a tissue site having a substantially gas impermeable, flexible mat. A plurality of projections extend from a surface of the substantially gas impermeable, flexible mat, and each projection has a first end connected to the surface and a second end opposing the first end. A flexible membrane is positioned adjacent the second end of at least a portion of the plurality of projections and the flexible membrane is sufficiently flexible to allow deformation of the flexible membrane by the at least the portion of the plurality of projections when a biasing force exerted on the substantially gas impermeable, flexible mat or the plurality of projections is greater than or equal to a threshold force.
摘要:
A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB.
摘要:
A dressing for promoting healing and pain relief of the body of a living organism having a pathologic condition has at least one layer of conductive material having a resistance no greater than 1000 Ω/cm2. When placed proximate a portion of the body of the living organism suffering from the pathologic condition, the dressing alters the electrodynamic processes occurring in conjunction with said pathologic condition to promote healing and pain relief in the living organism. When used as a wound dressing, the conductive material is placed in contact with tissue around the periphery of the wound and with the wound, lowering the electrical potential and resistance of the wound and increasing the wound current.
摘要翻译:用于促进具有病理状况的活体的身体的愈合和疼痛缓解的敷料具有至少一层电阻不大于1000和OHgr / cm 2的导电材料。 当放置在患有病理状况的活体的身体的一部分附近时,敷料改变与所述病理状况结合发生的电动过程,以促进活体中的愈合和疼痛缓解。 当用作伤口敷料时,导电材料与伤口周围的组织和伤口接触,降低伤口的电位和电阻并增加伤口电流。
摘要:
The present invention is directed to a composition comprising a plurality of small, liquid-expandable articles and their use to induce hemostasis when applied to bleeding wounds.
摘要:
An absorbent wound care device comprising a layer of an absorbent material, said layer having a wound contacting surface, wherein the wound contacting surface is provided with a wound contacting layer in the form of a layer of an elastic material in the form of fibre threads forming a uniform layer of intersecting fibre threads covering at least a part of the surface of the absorbent material provides a non/low-adhesive flexible, highly absorbent wound dressing being capable of absorbing large amounts of wound exudates without giving rise to gel blocking and/or maceration, pressure marks nor leaving residues of the dressing in the wound and does not cause damage to fragile skin when removing the dressing and allows for easy access for wound exudates and slough to an absorbent layer, which ensures a fast initial absorption of an absorbing dressing.
摘要:
Methods and devices for transmitting micromechanical forces locally to induce surface convolutions into tissues on the millimeter to micron scale for promoting wound healing are presented. These convolutions induce a moderate stretching of individual cells, stimulating cellular proliferation and elaboration of natural growth factors without increasing the size of the wound. Micromechanical forces can be applied directly to tissue, through biomolecules or the extracellular matrix. This invention can be used with biosensors, biodegradable materials and drug delivery systems. This invention will also be useful in pre-conditioned tissue-engineering constructs in vitro. Application of this invention will shorten healing times for wounds and reduce the need for invasive surgery.
摘要:
A coating composition is described for the anti-adhesive coating of wound dressings, comprising a nanosol that contains silica and at least one hydrophobic organic silicon compound, anti-adhesive layers prepared therefrom, coated wound dressings and methods for their manufacture.
摘要:
The present invention provides a new wound-covering material. The wound-covering material is produced by carbonizing a silk material at temperature of 500-1000° C., and a large number of microfine holes are formed in a surface of the silk carbonized body. By carbonizing at such low temperature, the silk carbonized body has flexibility of the silk material, a significant antibacterial property, a high water-absorbing property and a high water absorption rate, so that the silk carbonized body is suitable for the wound-covering material.