摘要:
The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologs thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologs thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.
摘要:
Disclosed is a system for real-time detection and annunciation of blood associated with menstruation and surgical wounds. The system comprises a real-time, wide area blood detector, communication means for relay of blood detection information, and annunciation means to inform the user of the emanation of blood. Various system embodiments include local and remote as well as covert and non-covert annunciation to users or medical personnel, various forms of real-time blood detection sensors, blood analysis capability, and smart bandage telemetry.
摘要:
Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.
摘要:
The invention relates to a method for producing hydrophilic, aliphatic polyurethane foams. The invention further relates to special compositions for producing polyurethane foams either using the method according to the invention or using the polyurethane foams obtained from the compositions according to the invention, and to the use of the polyurethane foams as a wound dressing, cosmetic item, or incontinence product.
摘要:
The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.
摘要:
An apparatus for promoting granulation and epithelialisation at a tissue site having a substantially gas impermeable, flexible mat. A plurality of projections extend from a surface of the substantially gas impermeable, flexible mat, and each projection has a first end connected to the surface and a second end opposing the first end. A flexible membrane is positioned adjacent the second end of at least a portion of the plurality of projections and the flexible membrane is sufficiently flexible to allow deformation of the flexible membrane by the at least the portion of the plurality of projections when a biasing force exerted on the substantially gas impermeable, flexible mat or the plurality of projections is greater than or equal to a threshold force.
摘要:
The present invention relates to fiber compositions comprising gels or hydrogels. The invention further relates to the composition of a gel or hydrogel loaded biodegradable fiber and methods of fabricating such fibers. The present invention further provides tissue engineering and drug-delivery compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The invention also relates to methods of manipulating the rate of therapeutic agent release by changing both the biodegradable polymer properties as well as altering the properties of the incorporated gel or hydrogel.
摘要:
Provided is an individually-wrapped sanitary napkin N, in which a sanitary napkin 1 is folded lengthwise with a wrapping sheet 10 and wrapped individually, the sanitary napkin 1 including an inner surface sheet 3 that constitutes a skin-contacting surface layer and a pair of wing-like flaps W that have wing adhesive layers 9 for fixing the wing-like flaps W to the underwear. The wing-like flaps W are both folded to the skin-contacting surface side, and the wing adhesive layers 9, provided in the folded portions of the wing-like flaps W, are collectively covered by a wing separating sheet 12, and a functional chemical 20 having a specific function is contained in the inner surface sheet 3 in the area where the wing separating sheet 12 is layered.
摘要:
A seat protection pad to protect a seat against spilled liquids and other bodily fluids including human and animal fluids, including a base pad having a first side and a second side and a front portion, a mid-section portion and a rear portion, wherein the base pad includes a base pad opening located between the mid-section portion and the front portion, an upper pad having a first side and a second side and a front end and a rear end, wherein the upper pad is attached to the first side of the base pad at a location adjacent to the front portion of the base pad such that the second side of the upper pad is located adjacent to the first side of the base pad, an upper pad opening located between the front end of the upper pad and the front portion of the base pad such that the upper pad opening is aligned with the base pad opening to allow a seat belt buckle to be inserted through the base pad opening and the upper pad opening, a plurality of adhesive strips located on the second side of the base pad, wherein a first one of the plurality of adhesive strips is attached adjacent to the rear portion of the base pad, a second one of the plurality of adhesive strips is attached adjacent to the mid-section portion of the base pad and a third one of the plurality of adhesive strips is attached adjacent to the front portion of the base pad, and a plurality of stitches located on each of the plurality of adhesive strips for securing the plurality of adhesive strips to the base pad.
摘要:
Provided are: a glass composition for wound care, which promotes a wound healing process by providing a moist environment and nutrients necessary for growth of epidermal cells, and which has bactericidal properties for preventing critical fixing of bacteria to a wound surface and infection with bacteria; and a wound covering material that uses the glass composition. The glass composition contains, by mass % in terms of oxides, 5 to 70% of SiO2, 0 to 10% of Al2O3, 5 to 40.0% of B2O3, and 1 to 50% of CaO.