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公开(公告)号：US20240082324A1
公开(公告)日：2024-03-14
申请号：US18501174
申请日：2023-11-03
发明人： Eiji KOBATAKE , Toshihide KABUKI
IPC分类号： A61K35/747 , A23L33/195
CPC分类号： A61K35/747 , A23L33/195 , C12R2001/225
摘要： A method to stimulate β-defensin production in oral epithelial cells of a subject in need thereof, that includes administering a food or drink containing Lactobacillus helveticus cells to a subject in need of stimulating β-defensin production in oral epithelial cells.
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公开(公告)号：US20190269763A1
公开(公告)日：2019-09-05
申请号：US16416770
申请日：2019-05-20
发明人： Aiko OHMACHI , Hiroaki MATSUYAMA , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA , Hiroshi UENO , Hiroshi URAZONO
摘要： A powdered milk product that includes angiogenin and/or angiogenin hydrolysate in an amount of 1.4 to 24 mg/15 g, and cystatin and/or cystatin hydrolysate in a mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.03 to 1.3.
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公开(公告)号：US20190124945A1
公开(公告)日：2019-05-02
申请号：US16082784
申请日：2017-03-07
发明人： Shojiro TAMAKI , Akira TOMIZAWA , Mayumi SHIBA , Makoto TAKANO , Hiroshi IMAI
摘要： A method for fractionating whey proteins, including: preparing a solution including a first whey protein and a second whey protein and separating the first whey protein and the second whey protein with a membrane; wherein the first whey protein forms a complex with at least one of carbonate ion, hydrogen carbonate ion, a light metal ion, and a transition metal ion; and the second whey protein satisfies at least one of the following (1) and (2): (1) the second whey protein forms no complex with any of the carbonate ion and the hydrogen carbonate ion; (2) the second whey protein forms no complex with any of the light metal ions and the transition metal ions.
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公开(公告)号：US20190091304A1
公开(公告)日：2019-03-28
申请号：US16204155
申请日：2018-11-29
发明人： Aiko OHMACHI , Hiroaki MATSUYAMA , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA
摘要： The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate hi an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.
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公开(公告)号：US09861687B2
公开(公告)日：2018-01-09
申请号：US15684175
申请日：2017-08-23
发明人： Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa
IPC分类号： A61K38/54 , A61K38/46 , A23L33/18 , A23L33/17 , A23K50/40 , A23K20/189 , A23K20/142 , A23K20/147 , A23L2/66 , A61K38/44 , A61K38/18
CPC分类号： A61K38/54 , A23K20/142 , A23K20/147 , A23K20/189 , A23K50/40 , A23L2/66 , A23L33/17 , A23L33/18 , A23V2002/00 , A23V2200/00 , A61K38/1891 , A61K38/44 , A61K38/465 , C12Y111/01007 , C12Y301/27 , A61K2300/00 , A23V2200/306
摘要： The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and lactoperoxidase and/or lactoperoxidase hydrolysate, in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.3 to 20.
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公开(公告)号：US20170325472A1
公开(公告)日：2017-11-16
申请号：US15665927
申请日：2017-08-01
发明人： Aiko OHMACHI , Hiroaki MATSUYAMA , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA , Hiroshi UENO , Hiroshi URAZONO
CPC分类号： A23C19/09 , A23C19/053 , A23C19/0688 , A23C19/082 , A23L33/18 , A23V2002/00 , A23V2200/00 , A23V2200/306 , A23V2250/55 , A61K35/20 , A61K38/465 , A61K38/57 , C12Y301/27
摘要： The invention relates to a cheese includes angiogenin and/or angiogenin hydrolysate in an amount of 6.5 mg/100 g to 160 mg/100 g, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.02 to 1.6.
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公开(公告)号：US09763868B2
公开(公告)日：2017-09-19
申请号：US14863477
申请日：2015-09-24
发明人： Hiroshi Ueno , Yoshikazu Morita , Aiko Ono , Ken Katoh , Noriko Ueda
IPC分类号： A61K8/64 , A61K8/67 , A61Q19/00 , A61K38/18 , A23L2/66 , A61Q19/08 , A23L2/02 , A23L2/52 , A61K38/01 , A23L33/17 , A23L33/175 , A23L33/18 , A23L33/19
CPC分类号： A61K8/64 , A23L2/02 , A23L2/52 , A23L2/66 , A23L33/17 , A23L33/175 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K8/676 , A61K38/018 , A61K38/1841 , A61K2800/592 , A61K2800/74 , A61Q19/00 , A61Q19/007 , A61Q19/08 , A23V2200/318 , A23V2250/54
摘要： A problem of the present invention is to provide a skin collagen production-promoting agent without safety problems. Another problem of the present invention is to provide a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product containing such a substance. TGF-β and/or a TGF-β degradation product, which is acquired by degrading TGF-β with a protease such as pepsin, pancreatin, etc., are used as a skin collagen production-promoting agent or the active ingredient of a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product. The aforementioned TGF-β and/or TGF-β degradation product have an effect of increasing the collagen content of the skin.
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公开(公告)号：US20170173082A1
公开(公告)日：2017-06-22
申请号：US15450596
申请日：2017-03-06
发明人： Aiko OHMACHI , Hiroaki MATSUYAMA , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA , Hiroshi UENO , Hiroshi URAZONO
CPC分类号： A61K35/20 , A23C9/1213 , A23C9/1307 , A23C9/1315 , A23C9/1322 , A23C9/1465 , A23L2/38 , A23V2002/00 , A61K38/443 , A61K38/465 , C12Y111/01007 , C12Y301/27 , A23V2200/306
摘要： The invention relates to provide a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
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公开(公告)号：US09629878B2
公开(公告)日：2017-04-25
申请号：US14418285
申请日：2012-07-31
申请人： Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
发明人： Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
CPC分类号： A61K35/20 , A23C9/1213 , A23C9/1307 , A23C9/1315 , A23C9/1322 , A23C9/1465 , A23L2/38 , A23V2002/00 , A61K38/443 , A61K38/465 , C12Y111/01007 , C12Y301/27 , A23V2200/306
摘要： The invention relates to provide a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
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公开(公告)号：US20150343030A1
公开(公告)日：2015-12-03
申请号：US14418261
申请日：2012-07-31
申请人： Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
发明人： Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
CPC分类号： A61K38/465 , A23C9/1465 , A23C9/1512 , A23C9/1526 , A23L2/52 , A23V2002/00 , A61K38/44 , C12Y111/01007 , C12Y301/27 , A23V2200/306
摘要： The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/100 ml and not more than 150 mg/100 ml, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
摘要翻译： 本发明涉及一种饮料，其含量大于0.8mg / 100ml且不超过150mg / 100ml的血管生成素和/或血管生成素水解产物，以及与血管生成素的质量比的乳过氧化物酶和/或乳过氧化物酶水解产物和/ 或血管生成素水解物为0.3〜23。
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