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    System for in vivo biosensing based on the optical response of electronic polymers
    71.
    发明授权
    System for in vivo biosensing based on the optical response of electronic polymers 失效
    基于电子聚合物的光学响应的​​体内生物传感系统

    公开(公告)号：US08326389B2

    公开(公告)日：2012-12-04

    申请号：US12517966

    申请日：2007-12-05

    申请人： Arthur J. Epstein ,  Louis R. Nemzer

    发明人： Arthur J. Epstein ,  Louis R. Nemzer

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14735 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/14865 ,  A61B5/681

    摘要： A system for continuous in vivo biosensing of specific analyte molecule concentrations based on the dynamic optical properties of electronic polymers is disclosed. The biosensor system includes at least one implant member subcutaneously exposed to the interstitial fluid of the subject, and a reader member at least temporarily positioned over the implant member to probe it with light of specific wavelengths through the skin. The system has many potential applications, including the real-time monitoring of blood glucose levels in diabetics as a method to supplement or replace conventional capillary blood testing.

    摘要翻译： 公开了一种基于电子聚合物的动态光学性质的特定分析物分子浓度的连续体内生物传感的系统。 生物传感器系统包括皮下暴露于受试者的间质液体的至少一个植入物构件，以及读取器构件，其至少临时定位在植入构件上方，以通过皮肤的特定波长的光探测它。 该系统具有许多潜在应用，包括实时监测糖尿病患者的血糖水平，作为补充或替代常规毛细血管血液检测的方法。

    ADJUSTABLE INTRAOCULAR LENS
    72.
    发明申请
    ADJUSTABLE INTRAOCULAR LENS 审中-公开
    可调节内窥镜

    公开(公告)号：US20120268710A1

    公开(公告)日：2012-10-25

    申请号：US13537939

    申请日：2012-06-29

    申请人： Vincent D. McGinniss ,  Steven M. Risser ,  Cynthia J. Roberts

    发明人： Vincent D. McGinniss ,  Steven M. Risser ,  Cynthia J. Roberts

    IPC分类号： G02C7/04 ,  C08F120/18 ,  C08F126/02

    CPC分类号： A61F2/1627 ,  A61F2/1635 ,  A61F2/1659 ,  A61F2002/16965 ,  A61L27/50 ,  A61L2430/16 ,  G02B1/043

    摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

    摘要翻译： 公开了用于改变诸如人工晶状体的透镜的功率的方法和装置。 在一种方法中，透镜包含含有可交联侧基的单一聚合物基质，其中当交联时聚合物基体的体积增加。 镜头不含有游离单体。 当暴露于紫外线辐射时，交联使得透镜的暴露部分体积增加，导致折射率增加。 在另一种方法中，透镜包含含有可光漂白的发色团的聚合物基质。 在紫外线照射下，光漂白导致曝光部分的折射率降低，透镜厚度没有变化。 这些方法避免了等待发生扩散以改变透镜形状的需要，并且避免了第二次暴露于辐射以锁定透镜变化的需要。

    Assessment device
    74.
    发明授权
    Assessment device 有权
    评估装置

    公开(公告)号：US08284070B2

    公开(公告)日：2012-10-09

    申请号：US12600123

    申请日：2008-05-14

    申请人： Ajit Chaudhari ,  Christopher McKenzie

    发明人： Ajit Chaudhari ,  Christopher McKenzie

    IPC分类号： G08B21/00

    CPC分类号： G01C9/00 ,  A61B5/1071 ,  A61B5/746 ,  A61B2505/03 ,  A61B2562/0219 ,  G01C25/00

    摘要： An assessment device is provided which allows for measurement of a position of interest, e.g., a body part, while a subject is in a functional position, such as may be required for the demands of an activity of interest without also requiring a lengthy setup time, tethered connection to other equipment external to the subject or tedious manual measurements. Moreover, an indicator such as an alarm or other output may be provided for receiving immediate, real time feedback, such as when a functional activity falls outside a tolerance or threshold.

    摘要翻译： 提供了一种评估装置，其允许测量感兴趣的位置，例如身体部位，而受试者处于功能位置，例如对感兴趣活动的需求可能需要，而不需要漫长的建立时间 ，连接到对象外部的其他设备或繁琐的手动测量。 此外，可以提供诸如报警或其他输出的指示器，用于接收即时的实时反馈，例如当功能活动超出容限或阈值时。

    Prothioconazole tolerant Cryptococcus flavescens strains for biological control of fusarium head blight
    80.
    发明授权
    Prothioconazole tolerant Cryptococcus flavescens strains for biological control of fusarium head blight 有权
    丙硫菌唑耐受性Cryptococcus flavescens菌株用于镰刀菌枯萎病的生物防治

    公开(公告)号：US08241889B2

    公开(公告)日：2012-08-14

    申请号：US12511275

    申请日：2009-07-29

    申请人： David A. Schisler ,  Michael J. Boehm

    发明人： David A. Schisler ,  Michael J. Boehm

    IPC分类号： C12N1/16 ,  A01N63/04

    CPC分类号： A01N63/04 ,  C12N1/14 ,  C12R1/645 ,  A01N43/653 ,  A01N2300/00

    摘要： Strains of Cryptococcus flavescens which are superior antagonists of F. graminearum for suppression and control of FHB in cereals, particularly in wheat and barley, are described. The strains are prothioconazole tolerant variants of previously described C. flavescens OH 182.9 (NRRL Y-30216). Moreover, these prothioconazole tolerant variants exhibit significantly increased efficacy against F. graminearum in comparison to the parent strain OH 182.9.

    摘要翻译： 描述了作为禾谷镰刀菌的优良拮抗剂的葡萄球菌菌株用于抑制和控制谷物中的FHB，特别是在小麦和大麦中。 该菌株是先前描述的C.flavescens OH 182.9（NRRL Y-30216）的丙硫菌唑耐受变体。 此外，与亲本菌株OH 182.9相比，这些丙硫菌唑耐受性变体表现出对禾谷镰刀菌的显着增加的功效。