公开(公告)号：US4661474A

公开(公告)日：1987-04-28

申请号：US807485

申请日：1985-12-10

申请人： Hamao Umezawa ,  Sumio Umezawa ,  Tsutomu Tsuchiya ,  Yoshiaki Takahashi

发明人： Hamao Umezawa ,  Sumio Umezawa ,  Tsutomu Tsuchiya ,  Yoshiaki Takahashi

IPC分类号： C07H15/236 ,  A61K31/71 ,  C07H15/234

CPC分类号： C07H15/234 ,  Y02P20/55

摘要： New compounds, 2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives thereof, particularly 1-N-(DL- or L-3-amino-2-hydroxypropionyl)- and 1-N-(L-4-amino-2-hydroxybutyryl)-2',3'-dideoxy-2'-fluorokanamycins A are now provided, which are each useful as antibacterial agent. 2',3'-Dideoxy-2'-fluorokanamycin A is prepared by a process comprising condensing a 6-azido-4-O-protected-2,3,6-trideoxy-2-fluoro-.alpha.-D-ribo-hexopyranosyl bromide with the 4-hydroxyl group of a 6-O-(2',4',6'-tri-O-protected-3'-N-protected-3'-amino-3'-deoxy-.alpha.-D-glucopyranosyl)-1,3-bis-N-protected-2-deoxystreptamine, reducing the resulting condensation product to convert its azido group into an amino group, and removing the remaining amino-protecting and hydroxyl-protecting groups from the reduction product.

摘要翻译： 新化合物2'，3'-二脱氧-2'-氟卡那霉素A及其1-N-（α-羟基-ω-氨基烷酰基）衍生物，特别是1-N-（DL-或L-3-氨基-2- 羟基丙酰基） - 和1-N-（L-4-氨基-2-羟基丁酰基）-2'，3'-二脱氧-2'-氟吗啉霉素A，其各自可用作抗菌剂。 2'，3'-二脱氧-2'-氟卡那霉素A通过以下方法制备，该方法包括将6-叠氮基-4-O-保护的2,3,6-三脱氧-2-氟-α-D-吡喃六氟肉豆蔻基 溴化物与6-O-（2'，4'，6'-三-O-保护的3'-N-保护的-3'-氨基-3'-脱氧-α-D- D-吡喃葡萄糖基）-1,3-双-N-保护的2-脱氧链霉胺，将所得缩合产物还原，将其叠氮基转化为氨基，并从还原产物中除去剩余的氨基保护基和羟基保护基团。

公开(公告)号：US4631490A

公开(公告)日：1986-12-23

申请号：US683447

申请日：1984-12-19

申请人： Yoshiaki Takahashi

发明人： Yoshiaki Takahashi

IPC分类号： H03F3/68 ,  H03F3/181 ,  H03F3/72

CPC分类号： H03F3/72

摘要： An audio output amplifying device which is adapted for use in a plurality of audio output amplifying circuits. An audio signal to be amplified is supplied to a positive phase input of a first differential amplifier. The positive phase input of a second differential amplifier is selectively coupled either to a source of a reference voltage (ground) or the source of the audio signal. A feedback circuit is connected between the output of the first differential amplifier and the negative phase inputs of both the first and second differential amplifiers. A switch is provided to selectively couple the output of the first differential amplifier to ground in one position and to allow amplification by both differential amplifiers in a second position.

摘要翻译： 一种音频输出放大装置，适用于多个音频输出放大电路。 要放大的音频信号被提供给第一差分放大器的正相输入。 第二差分放大器的正相输入选择性地耦合到参考电压（地）的源或音频信号的源。 反馈电路连接在第一差分放大器的输出端和第一和第二差分放大器的负相位输入端之间。 提供开关以选择性地将第一差分放大器的输出耦合到一个位置的地，并允许在第二位置的两个差分放大器进行放大。

公开(公告)号：US08148504B2

公开(公告)日：2012-04-03

申请号：US12227861

申请日：2007-06-01

申请人： Yoshihiko Kobayashi ,  Yoshihisa Akiyama ,  Takeshi Murakami ,  Nobuto Minowa ,  Masaki Tsushima ,  Yukiko Hiraiwa ,  Shoichi Murakami ,  Mitsuhiro Abe ,  Kazushige Sasaki ,  Shigeru Hoshiko ,  Toshiaki Miyake ,  Yoshiaki Takahashi ,  Daishiro Ikeda

发明人： Yoshihiko Kobayashi ,  Yoshihisa Akiyama ,  Takeshi Murakami ,  Nobuto Minowa ,  Masaki Tsushima ,  Yukiko Hiraiwa ,  Shoichi Murakami ,  Mitsuhiro Abe ,  Kazushige Sasaki ,  Shigeru Hoshiko ,  Toshiaki Miyake ,  Yoshiaki Takahashi ,  Daishiro Ikeda

IPC分类号： C07H13/02

CPC分类号： C07H15/234 ,  C07H15/224

摘要： This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.

摘要翻译： 本发明涉及对细菌具有强力抗微生物活性的新型氨基糖苷类抗生素，其诱导感染性疾病，特别是MRSA，并且没有显着的肾毒性，以及生产它们的方法。 更具体地，本发明涉及由式（Ia）表示的化合物或其药理学上可接受的盐或溶剂合物或其非对映体混合物，包含它们的抗微生物剂及其制备方法。

公开(公告)号：US20100252822A1

公开(公告)日：2010-10-07

申请号：US12678081

申请日：2008-09-10

申请人： Yoshiaki Takahashi

发明人： Yoshiaki Takahashi

IPC分类号： H01L51/54 ,  H01L51/56 ,  C08F230/04

CPC分类号： C09K11/06 ,  C08F226/06 ,  C09K2211/1425 ,  C09K2211/1466 ,  C09K2211/185 ,  H01L51/004 ,  H01L51/0085 ,  H01L51/5016

摘要： Phosphorescent polymer compounds of the invention have high light-emitting efficiency and long luminescent life. Organic electroluminescence devices have the phosphorescent polymer compounds.The phosphorescent polymer compounds include a structural unit that is derived from a compound of Formula (1) below in which L1 and L2 are specific ligands and are selected to satisfy the specific condition.

摘要翻译： 本发明的磷光聚合物化合物发光效率高，发光寿命长。 有机电致发光器件具有磷光聚合物化合物。 磷光聚合物化合物包括衍生自下述式（1）的化合物的结构单元，其中L1和L2是特异性配体并且被选择以满足特定条件。

公开(公告)号：US07808576B2

公开(公告)日：2010-10-05

申请号：US11839656

申请日：2007-08-16

申请人： Yoshiaki Takahashi ,  Hiroshi Nakamoto ,  Hidehiro Hanada

发明人： Yoshiaki Takahashi ,  Hiroshi Nakamoto ,  Hidehiro Hanada

IPC分类号： G02F1/1335 ,  G02F1/1345

CPC分类号： G02F1/133615 ,  G02B6/0021 ,  G02B6/0038 ,  G02B6/0046 ,  G02B6/0068 ,  G02B6/0073 ,  G02B6/0083 ,  G02B6/0091 ,  G02F2001/133314

摘要： The present invention provides a backlight of a liquid crystal display device having an inclination surface on a light guide plate and preventing a breakage of a liquid crystal panel, wherein light which leaks from the inclination surface is made to return to the light guide plate and the adhesiveness of the light guide plate and a flexible printed circuit board is increased. In a liquid crystal display device having a backlight which radiates light to a liquid crystal panel, LEDs are formed on a light guide plate formed on the backlight as light emitting elements. Between the plurality of light emitting elements, a projecting portion of the light guide plate is formed, and a reflection member is formed on an adhesive sheet which adheres a projection member and a flexible printed circuit board to each other. By arranging the reflective member and the cushion member close to an inclination surface, light from the inclination surface is made to return to a light guide plate side, and an external force from the outside can be alleviated by a cushion member.

摘要翻译： 本发明提供一种在导光板上具有倾斜面的液晶显示装置的背光源，并且防止了液晶面板的破损，使得从倾斜面泄漏的光返回到导光板， 导光板和柔性印刷电路板的粘合性增加。 在具有向液晶面板照射光的背光源的液晶显示装置中，在作为发光元件的背光源上形成的导光板上形成LED。 在多个发光元件之间，形成导光板的突出部分，并且在将突出部件和柔性印刷电路板相互贴合的粘合片上形成反射部件。 通过将反射构件和缓冲构件配置成靠近倾斜面，使得来自倾斜面的光返回到导光板侧，并且可以通过缓冲构件减轻来自外部的外力。

公开(公告)号：US20100030421A1

公开(公告)日：2010-02-04

申请号：US12575212

申请日：2009-10-07

申请人： Kentaro YOSHIMURA ,  Kohei Sakurai ,  Nobuyasu Kanekawa ,  Yuichiro Morita ,  Yoshiaki Takahashi ,  Kenichi Kurosawa ,  Toshimichi Minowa ,  Masatoshi Hoshino ,  Yasuhiro Nakatsuka ,  Kotaro Shimamura ,  Kunihiko Tsunedomi ,  Shoji Sasaki

发明人： Kentaro YOSHIMURA ,  Kohei Sakurai ,  Nobuyasu Kanekawa ,  Yuichiro Morita ,  Yoshiaki Takahashi ,  Kenichi Kurosawa ,  Toshimichi Minowa ,  Masatoshi Hoshino ,  Yasuhiro Nakatsuka ,  Kotaro Shimamura ,  Kunihiko Tsunedomi ,  Shoji Sasaki

IPC分类号： B60W10/00

CPC分类号： B60W30/00 ,  B60K6/46 ,  B60K6/52 ,  B60L3/0023 ,  B60L3/003 ,  B60L3/0076 ,  B60L3/0092 ,  B60L15/2009 ,  B60L2240/12 ,  B60L2240/20 ,  B60L2240/24 ,  B60L2240/423 ,  B60L2250/26 ,  B60T7/12 ,  B60W10/04 ,  B60W10/06 ,  B60W10/08 ,  B60W10/10 ,  B60W10/18 ,  B60W10/20 ,  B60W20/00 ,  B60W40/08 ,  B60W40/10 ,  B60W50/02 ,  B60W50/0225 ,  B60W50/04 ,  B60W2510/20 ,  B60W2510/202 ,  B60W2520/14 ,  B60W2540/10 ,  B60W2540/12 ,  B60W2550/20 ,  B62D5/046 ,  B62D5/0481 ,  B62D6/00 ,  G06F11/0796 ,  Y02T10/6217 ,  Y02T10/6265 ,  Y02T10/6286 ,  Y02T10/645 ,  Y02T10/72 ,  Y02T10/7275 ,  Y02T90/16

摘要： A vehicle control system which can ensure high reliability, real-time processing, and expandability with a simplified ECU configuration and a low cost by backing up an error through coordination in the entire system without increasing a degree of redundancy of individual controllers beyond the least necessary level. The vehicle control system comprises a sensor controller for taking in sensor signals indicating a status variable of a vehicle and an operation amount applied from a driver, a command controller for generating a control target value based on the sensor signals taken in by the sensor controller, and an actuator controller for receiving the control target value from the command controller and operating an actuator to control the vehicle, those three controller being interconnected via a network. The actuator controller includes a control target value generating unit for generating a control target value based on the sensor signals taken in by the sensor controller and received by the actuator controller via the network when the control target value generated by the command controller is abnormal, and controls the actuator in accordance with the control target value generated by the control target value generating unit.

摘要翻译： 一种车辆控制系统，可以通过简化的ECU配置和低成本确保高可靠性，实时处理和可扩展性，通过整个系统中的协调备份错误，而不会增加单个控制器的冗余程度，超出最不必要的范围 水平。 车辆控制系统包括：传感器控制器，用于接收指示车辆的状态变量的传感器信号和从驾驶员施加的操作量;命令控制器，用于基于由传感器控制器接收的传感器信号产生控制目标值; 以及致动器控制器，用于从命令控制器接收控制目标值并操作致动器来控制车辆，这三个控制器经由网络互连。 执行器控制器包括控制目标值产生单元，用于当由指令控制器产生的控制目标值异常时，基于由传感器控制器接收并由致动器控制器经由网络接收的传感器信号产生控制目标值;以及 根据由控制目标值产生单元产生的控制目标值来控制致动器。

公开(公告)号：US20090209744A1

公开(公告)日：2009-08-20

申请号：US12378172

申请日：2009-02-11

申请人： Yoshiaki Takahashi ,  Masayuki Igarashi

发明人： Yoshiaki Takahashi ,  Masayuki Igarashi

IPC分类号： C07H19/06

CPC分类号： A61K31/7072 ,  A01N43/62

摘要： An antibacterial agent having high antibacterial activity against Mycobacterium avium subsp. paratuberculosis is provided. Specifically, the antibacterial agent of the present invention having high antibacterial activity against Mycobacterium avium subsp. paratuberculosis is a caprazamycin derivative represented, for example, by the following general formula (II): wherein Me is a methyl group; and R1 is a straight or substantially straight chain alkyl group having 5 to 21 carbon atoms, a straight or substantially straight chain alkenyl group having 5 to 21 carbon atoms, a cycloalkyl group having 5 to 12 carbon atoms, or a phenyl group substituted at the para-position with a straight chain alkyl group having 1 to 14 carbon atoms, a straight chain alkoxy group having 1 to 9 carbon atoms or a cycloalkyl group having 5 to 12 carbon atoms.

摘要翻译： 对鸟分枝杆菌亚种具有高抗菌活性的抗菌剂 提供副结核病。 具体地说，本发明的抗菌剂对鸟分枝杆菌属 副结核病是例如由以下通式（II）表示的卡拉霉素衍生物：其中Me是甲基; R1为碳原子数5〜21的直链或直链状的直链状烷基，碳原子数5〜21的直链或直链状的链烯基，碳原子数5〜12的环烷基， 具有1至14个碳原子的直链烷基的对位位置，具有1至9个碳原子的直链烷氧基或具有5至12个碳原子的环烷基。

公开(公告)号：US07570321B2

公开(公告)日：2009-08-04

申请号：US11481862

申请日：2006-07-07

申请人： Yoshiaki Takahashi ,  Masahiko Kurihara ,  Masayuki Mifune ,  Ken Kagabu

发明人： Yoshiaki Takahashi ,  Masahiko Kurihara ,  Masayuki Mifune ,  Ken Kagabu

IPC分类号： G02F1/1335 ,  F21V7/04

CPC分类号： G02B6/009 ,  G02B6/0018 ,  G02B6/0038 ,  G02B6/0083 ,  G02F1/133615 ,  G02F1/13452 ,  H05K1/189

摘要： A liquid crystal display device having includes a light guide plate having a surface thereof serving as an illuminating surface region opposite to a liquid crystal display panel, light sources mounted on a flexible printed-circuit board and provided on a side face of the light guide plate, an optical sheet member interposed between the liquid crystal display panel and the light guide plate. The side surfaces of the light guide plate with the light sources provided thereon have a ridge-like inclined surface formed thereon, when viewed from the illuminating surface, and the ridge-like inclined surfaces serve as a light-receiving surface with the light source arranged thereon.

摘要翻译： 一种液晶显示装置，包括：导光板，其表面用作与液晶显示面板相反的照明面区域，光源安装在柔性印刷电路板上，设置在导光板的侧面 插入在液晶显示面板和导光板之间的光学片构件。 设置有光源的导光板的侧面在从照明面观察时具有形成在其上的脊状倾斜面，并且脊状倾斜面用作光接收面，光源布置成 上。

公开(公告)号：US20090186841A1

公开(公告)日：2009-07-23

申请号：US12227861

申请日：2007-06-01

申请人： Yoshihiko Kobayashi ,  Yoshihisa Akiyama ,  Takeshi Murakami ,  Nobuto Minowa ,  Masaki Tsushima ,  Yukiko Hiraiwa ,  Shoichi Murakami ,  Mitsuhiro Abe ,  Kazushige Sasaki ,  Shigeru Hoshiko ,  Toshiaki Miyake ,  Yoshiaki Takahashi ,  Daishiro Ikeda

发明人： Yoshihiko Kobayashi ,  Yoshihisa Akiyama ,  Takeshi Murakami ,  Nobuto Minowa ,  Masaki Tsushima ,  Yukiko Hiraiwa ,  Shoichi Murakami ,  Mitsuhiro Abe ,  Kazushige Sasaki ,  Shigeru Hoshiko ,  Toshiaki Miyake ,  Yoshiaki Takahashi ,  Daishiro Ikeda

IPC分类号： A61K31/7036 ,  C07H15/234 ,  A61P31/04

CPC分类号： C07H15/234 ,  C07H15/224

摘要： This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.

摘要翻译： 本发明涉及对细菌具有强力抗微生物活性的新型氨基糖苷类抗生素，其诱导感染性疾病，特别是MRSA，并且没有显着的肾毒性，以及生产它们的方法。 更具体地，本发明涉及由式（Ia）表示的化合物或其药理学上可接受的盐或溶剂合物或其非对映体混合物，包含它们的抗微生物剂及其制备方法。

公开(公告)号：US20090059621A1

公开(公告)日：2009-03-05

申请号：US12198141

申请日：2008-08-26

申请人： Yoshiaki Takahashi ,  Masayuki Mifune ,  Hiroshi Nakamoto ,  Michihide Shibata ,  Akiyoshi Tobe

发明人： Yoshiaki Takahashi ,  Masayuki Mifune ,  Hiroshi Nakamoto ,  Michihide Shibata ,  Akiyoshi Tobe

IPC分类号： F21V7/04

CPC分类号： G02B6/0036 ,  G02B6/0028 ,  G02B6/0061 ,  G02B6/0068 ,  G02B6/0073

摘要： In a backlight which arranges light emitting diodes on a side surface of a light guide plate, irregularities of radiation light from the backlight can be decreased. In a liquid crystal display device having a backlight which radiates light to a liquid crystal panel, LEDs which constitute a light emitting element are mounted on a light guide plate formed on the backlight, and teardrop-shaped lenses are formed on a light radiation surface of the light guide plate. By changing the advancing directions of lights radiated from the light emitting element using the teardrop-shaped lenses, it is possible to decrease irregularities of a planar light source by scattering the radiation lights from the light guide plate.

摘要翻译： 在将发光二极管配置在导光板的侧面的背光源中，可以减少来自背光源的放射线的不规则性。 在具有向液晶面板照射光的背光的液晶显示装置中，构成发光元件的LED被安装在形成在背光源上的导光板上，并且泪珠状透镜形成在 导光板。 通过使用泪珠状透镜改变从发光元件辐射的光的前进方向，可以通过散射来自导光板的辐射光来减小平面光源的不规则性。