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公开(公告)号:US11639240B2
公开(公告)日:2023-05-02
申请号:US17481605
申请日:2021-09-22
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin , Jeremy K. Larsen , Patrick L. Draper , Brandon M. Knudsen
Abstract: A fluid manifold system includes a first manifold having portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. The fluid flow path of the first manifold includes: a primary flow path communicating with the fluid inlet of the first manifold; and a plurality of spaced apart secondary flow paths that branch off of the primary flow path. Each secondary flow path has a first end communicating with the primary flow path and an opposing second end, each secondary flow path having a diameter that is smaller than a diameter of the primary flow path. The fluid manifold system also includes a plurality of tubular connectors with each tubular connector being secured to the first manifold at the second end of a corresponding one of the secondary flow paths.
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公开(公告)号:US20220033753A1
公开(公告)日:2022-02-03
申请号:US17450812
申请日:2021-10-13
Applicant: Life Technologies Corporation
Inventor: Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
Abstract: A system for oxygenating a biological culture includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween; a tubular member projecting into the compartment of the container and terminating at a terminal end; a gas supply coupled with the tubular member and being configured to blow gas through the tubular member; and a mixing element disposed within compartment of the container at a location between the terminal end of the tubular member and the bottom wall of the container, the mixing element being configured to mix the liquid.
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公开(公告)号:US20210069654A1
公开(公告)日:2021-03-11
申请号:US16953066
申请日:2020-11-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin , Nephi D. Jones , Derik R. West
Abstract: A container assembly includes a flexible bag having an interior surface bounding a chamber and an opposing exterior surface. The bag has a bottom end wall that includes a first sparger and a second sparger. The first sparger and the second sparger each have a flexible first sheet overlying a flexible second sheet, the first sheet and the second sheet being secured together so as to form a sparging area bounded between the first sheet and the second sheet, at least a portion of the first sheet overlying the sparging area being gas permeable so that gas can pass from the sparging area, through the first sheet, and into the chamber.
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公开(公告)号:US20200231922A1
公开(公告)日:2020-07-23
申请号:US16715087
申请日:2019-12-16
Applicant: Life Technologies Corporation
Inventor: Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
Abstract: A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween. A tube has a first end and an opposing second end, the first end of the tube being disposed within the compartment of the container. A nozzle is disposed within the compartment of the container and has at least one outlet, the nozzle being coupled with the tube so that a gas can be passed through the tube and out the at least one outlet of the nozzle. The nozzle is sufficiently buoyant so that when a fluid is disposed within the compartment of the container, the nozzle floats on the fluid.
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公开(公告)号:US10711233B2
公开(公告)日:2020-07-14
申请号:US15374689
申请日:2016-12-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Clinton C. Staheli , Nephi D. Jones , Michael E. Goodwin
IPC: C12M3/00 , C12N1/00 , C12M1/00 , B01D5/00 , B01F3/04 , B01F7/00 , B01F7/16 , B01F7/18 , B01F15/00 , C12M1/06 , C12M1/12 , F28F21/06 , B01D47/05 , C12N1/10 , C12N1/12 , C12N1/14 , C12N1/20 , C12N5/00 , C12N5/04 , B01F7/22 , B01F15/06 , C12M1/02 , F28B1/02 , F28F3/12 , C12N5/10 , F28D21/00
Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.
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公开(公告)号:US20180321089A1
公开(公告)日:2018-11-08
申请号:US16034122
申请日:2018-07-12
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin
Abstract: A container system includes a flexible bag, a probe port, and a probe. The probe port includes an elongated tubular member having an interior surface bounding a first passageway extending between a first end and an opposing second end, the tubular member being made of a polymeric or elastomeric material and being flexible. The probe port also includes a flange coupled to the tubular member and radially outwardly projecting therefrom, the flange being secured to the flexible bag so that the first end of the tubular member projects into a chamber of the flexible bag while the second end of the first passageway of the tubular member is accessible from outside of the flexible bag. The probe can be received within the first passageway of the probe port.
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公开(公告)号:US20180187809A1
公开(公告)日:2018-07-05
申请号:US15863031
申请日:2018-01-05
Applicant: Life Technologies Corporation
Inventor: Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
IPC: F16L33/207 , F16L33/22
Abstract: A method for coupling a tube to a tube fitting includes radially outwardly expanding a tubular compression collar from a constricted state to an expanded state, the compression collar having a throughway extending there through and being made of a resiliently flexible material. An end of the tube is inserted within the throughway of the expanded compression collar, the tube bounding a passageway. A tube fitting is inserted within the passageway of the tube. The compression collar is allowed to resiliently rebound back towards the constricted state so that the compression collar pushes the tube against the tube fitting.
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公开(公告)号:US20170307447A1
公开(公告)日:2017-10-26
申请号:US15645549
申请日:2017-07-10
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin
CPC classification number: G01K1/14 , B01F2215/0073 , C12M1/26 , C12M1/28 , C12M23/14 , C12M23/26 , C12M23/46 , C12M27/02 , C12M29/06 , C12M33/00 , C12M41/12 , G01N1/10 , G01N2001/1037 , Y10T137/86292 , Y10T137/863
Abstract: A container system includes a flexible bag, a probe port, and a probe. The probe port includes an elongated tubular member having an interior surface bounding a first passageway extending between a first end and an opposing second end, the tubular member being made of a polymeric or elastomeric material and being flexible. The probe port also includes a flange coupled to the tubular member and radially outwardly projecting therefrom, the flange being secured to the flexible bag so that the first end of the tubular member projects into a chamber of the flexible bag while the second end of the first passageway of the tubular member is accessible from outside of the flexible bag. The probe is received within the first passageway of the probe port.
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公开(公告)号:US09726551B2
公开(公告)日:2017-08-08
申请号:US14450102
申请日:2014-08-01
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin
CPC classification number: G01K1/14 , B01F2215/0073 , C12M1/26 , C12M1/28 , C12M23/14 , C12M23/26 , C12M23/46 , C12M27/02 , C12M29/06 , C12M33/00 , C12M41/12 , G01N1/10 , G01N2001/1037 , Y10T137/86292 , Y10T137/863
Abstract: A container system includes a flexible bag bounding a chamber. A probe port includes an elongated tubular member having an interior surface bounding a first passageway and extending between a first end and an opposing second end, the first passageway being closed at the first end and open at the second end; and a flange encircling and radially outwardly projecting from the tubular member at or toward the second end thereof, the flange being secured to the flexible bag so that the first end of the elongated tubular member projects into the chamber of the flexible bag while the open second end of the elongated tubular member is accessible from outside of the flexible bag. A probe is received within the first passageway of the probe port.
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公开(公告)号:US20170088806A1
公开(公告)日:2017-03-30
申请号:US15376362
申请日:2016-12-12
Applicant: LIFE TECHNOLOGIES CORPORATION , Baxalta Incorporated , Baxalta GmbH
Inventor: Kurt T. Kunas , Robert V. Oakley , Fauad F. Hasan , Michael E. Goodwin , Jeremy K. Larsen , Nephi D. Jones
CPC classification number: C12M23/14 , B01F7/001 , B01F7/1695 , B01F7/22 , B01F15/00006 , B01F15/00831 , B01F15/0085 , B01F2215/0073 , C12M23/00 , C12M23/06 , C12M23/26 , C12M23/28 , C12M27/02 , C12M29/06 , Y10T29/49826
Abstract: A reactor system includes a support housing having an interior surface bounding a chamber, the chamber having a vertically extending central longitudinal axis. A flexible bag is disposed within the chamber of the support housing and has an interior surface bounding a compartment. A mixing element is disposed within the compartment of the flexible bag. A drive element, such as a drive shaft, is secured the mixing element, wherein the mixing element is laterally offset from and/or is angled relative to the vertically extending central longitudinal axis of the support housing.
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