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159 条记录 (耗时 0.029 秒)

    NUCLEIC ACID SEQUENCING
    72.
    发明申请
    NUCLEIC ACID SEQUENCING 有权
    核酸序列

    公开(公告)号：US20120046176A1

    公开(公告)日：2012-02-23

    申请号：US12860462

    申请日：2010-08-20

    申请人： Xing Su ,  Kai Wu ,  Liming Wang ,  Jianquan Liu ,  Grace M. Credo

    发明人： Xing Su ,  Kai Wu ,  Liming Wang ,  Jianquan Liu ,  Grace M. Credo

    IPC分类号： C40B20/00

    CPC分类号： C12Q1/6874 ,  C12Q2531/125 ,  C12Q2535/122 ,  C12Q2565/301 ,  C12Q2565/607

    摘要： Nucleic acid sequencing using concatemers of DNA is provided. Optionally, amplified reaction products from the repeated incorporation and excision of a nucleoside complementary to a nucleoside of the DNA to be sequenced onto primer molecules hybridized to the concatemers of DNA are detected. Nucleic acid sequencing using concatemers of DNA and non-natural oligonucleotides is also provided. Nucleic acid sequencing reactions are detected electronically and or optically using arrays of detectors.

    摘要翻译： 提供使用DNA连接子的核酸测序。 任选地，检测来自重复掺入和切除与待测序的DNA的核苷互补的核苷酸的扩增反应产物与DNA连接体杂交的引物分子上。 还提供了使用DNA和非天然寡核苷酸的并联体的核酸测序。 使用检测器阵列电子和/或光学检测核酸测序反应。

    Chemically induced optical signals and DNA sequencing
    73.
    发明申请
    Chemically induced optical signals and DNA sequencing 有权
    化学诱导光信号和DNA测序

    公开(公告)号：US20100330553A1

    公开(公告)日：2010-12-30

    申请号：US12459309

    申请日：2009-06-30

    申请人： Xing Su ,  Liming Wang ,  Jianquan Liu ,  Kai Wu

    发明人： Xing Su ,  Liming Wang ,  Jianquan Liu ,  Kai Wu

    IPC分类号： C12Q1/68 ,  C12M1/00 ,  G02B6/10

    CPC分类号： G02B6/1221 ,  C12Q1/6874 ,  C12Q2565/607 ,  C12Q2563/107 ,  C12Q2527/125

    摘要： Methods for sequencing nucleic acids are presented. Sequencing is accomplished through the chemical amplification of the products of DNA synthesis and the detection of the chemically amplified products. In embodiments of the invention, a substrate is provided having a plurality of molecules of DNA to be sequenced attached and a plurality of molecules capable of chelating pyrophosphate ions attached, the DNA molecules to be sequenced are primed, and a next complementary nucleotide is incorporated and excised a plurality of times leading to the buildup of pyrophosphate ions locally around the DNA molecule to be sequenced. Pyrophosphate ions are captured by the substrate-attached chelators and optically detected to determine the identity of the next complementary nucleic acid in the DNA molecule to be sequenced.

    摘要翻译： 介绍了核酸测序方法。 通过化学扩增DNA合成产物和化学扩增产物的检测来完成测序。 在本发明的实施方案中，提供了具有多个待测序的DNA分子的底物和能够螯合连接的焦磷酸根离子的多个分子，引入待测序的DNA分子，并且掺入下一个互补核苷酸， 切除多次导致待测序的DNA分子局部周围的焦磷酸盐离子的积聚。 焦磷酸根离子被底物附着的螯合剂捕获并光学检测以确定待测序的DNA分子中下一个互补核酸的同一性。

    Forming glass sheets with improved shape stability
    74.
    发明授权
    Forming glass sheets with improved shape stability 有权
    形成具有改善的形状稳定性的玻璃板

    公开(公告)号：US07818980B2

    公开(公告)日：2010-10-26

    申请号：US11606816

    申请日：2006-11-30

    申请人： Steven Roy Burdette ,  Longting He ,  Lewis Kirk Klingensmith ,  Liming Wang

    发明人： Steven Roy Burdette ,  Longting He ,  Lewis Kirk Klingensmith ,  Liming Wang

    IPC分类号： C03B17/00 ,  C03B17/06

    CPC分类号： C03B17/064 ,  C03B17/065 ,  Y10T428/24

    摘要： Systems, methods, apparatus and products relate to display glass from curved glass ribbons, to improve shape stability in glass ribbons, to creation of reduced stress glass ribbons, and to creation of improved shape stability and reduced stress of display glass, which may include forming slightly a curved glass ribbon in a fusion draw machine (FDM). One or more embodiments may include an isopipe having a desired curvature; an isopipe having a desired incline; an offset draw device operable to draw the glass ribbon in an inclined ribbon draw direction; one or more air jets or vacuum operable to apply air pressure to a first side of the glass ribbon, thereby creating a pressure differential on the first side; and/or one or more electrostatic force generators operable to apply electrostatic force to a first side of the glass ribbon, thereby generating an electric field differential across the glass ribbon.

    摘要翻译： 系统，方法，装置和产品涉及从弯曲的玻璃带展示玻璃，以改善玻璃带中的形状稳定性，产生减少应力的玻璃带，以及改善形状稳定性和降低显示玻璃的应力，这可能包括形成 在熔融拉丝机（FDM）中稍微弯曲的玻璃带。 一个或多个实施例可以包括具有期望曲率的等压槽; 具有期望倾斜度的等压槽; 偏移绘制装置，其可操作以将所述玻璃带拉伸成倾斜的带拉伸方向; 一个或多个空气喷嘴或真空可操作以将空气压力施加到玻璃带的第一侧，从而在第一侧上产生压力差; 和/或一个或多个静电力发生器可操作以将静电力施加到玻璃带的第一侧，由此在玻璃带上产生电场差。

    METHOD AND APPARATUS FOR CIPHERTEXT INDEXING AND SEARCHING
    75.
    发明申请
    METHOD AND APPARATUS FOR CIPHERTEXT INDEXING AND SEARCHING 审中-公开
    CIPHERTEXT索引和搜索的方法和装置

    公开(公告)号：US20100169321A1

    公开(公告)日：2010-07-01

    申请号：US12636493

    申请日：2009-12-11

    申请人： Liming Wang ,  Ye Tian ,  Toshikazu Fukushima ,  Hao Lei ,  Ke Zeng

    发明人： Liming Wang ,  Ye Tian ,  Toshikazu Fukushima ,  Hao Lei ,  Ke Zeng

    IPC分类号： G06F17/30

    CPC分类号： G06F21/6227 ,  G06F16/316

    摘要： The present invention provides a method and apparatus for ciphertext indexing and searching. Indices of multiple levels are created for the encrypted files. Each item in the primary index includes a primary index item identifier and the ciphertext of the primary indexing information of the related file. The primary indexing information each includes an identifier(s) of the related secondary index item identifier(s) and the corresponding decryption information. Each item in the secondary index includes a secondary index item identifier and the ciphertext of the secondary indexing information. Information necessary for obtaining a file is included in the corresponding secondary indexing information. With the decryption information of the secondary indexing information in the decrypted primary indexing information, the ciphertext of the related secondary indexing information is decrypted so as to obtain information such as the decryption key of the file.

    摘要翻译： 本发明提供了一种用于密文索引和搜索的方法和装置。 为加密文件创建多个级别的索引。 主索引中的每个项目都包含主索引项标识符和相关文件的主索引信息的密文。 主索引信息每个包括相关次要索引项标识符的标识符和对应的解密信息。 次要索引中的每个项目包括次索引项标识符和次索引信息的密文。 获得文件所需的信息被包括在相应的次索引信息中。 通过解密的主索引信息中的二次索引信息的解密信息，解密相关二次索引信息的密文，以获得诸如文件的解密密钥的信息。

    Optical lithography fluoride crystal annealing furnace
    80.
    发明授权
    Optical lithography fluoride crystal annealing furnace 失效
    光刻氟化物晶体退火炉

    公开(公告)号：US07198673B2

    公开(公告)日：2007-04-03

    申请号：US11059980

    申请日：2005-02-16

    申请人： John H. Brennan ,  Michael W. Price ,  Juergen Tinz ,  Liming Wang

    发明人： John H. Brennan ,  Michael W. Price ,  Juergen Tinz ,  Liming Wang

    IPC分类号： C30B11/00

    CPC分类号： C30B33/00 ,  C30B29/12 ,  Y10T117/10 ,  Y10T117/1016 ,  Y10T117/1024

    摘要： A method of making below 250-nm UV light transmitting optical fluoride lithography crystals includes applying heat along a shortest path of conduction of a selected optical fluoride crystal, heating the optical fluoride crystal to an annealing temperature, holding the temperature of the optical fluoride crystal at the annealing temperature, and gradually cooling the optical fluoride crystal to provide a low-birefringence optical fluoride crystal for transmitting below 250-nm UV light.

    摘要翻译： 制造低于250nm的UV光透射​​光学氟化物光刻晶体的方法包括沿着所选择的氟化物晶体的最短导通路径施加热量，将氟化物晶体加热到退火温度，将氟化物晶体的温度保持在 退火温度，并逐渐冷却光氟化物晶体，以提供低于250nm紫外光的低双折射氟化物晶体。