公开(公告)号：US20150328402A1

公开(公告)日：2015-11-19

申请号：US14281766

申请日：2014-05-19

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Keith Nogueira ,  Pratik Agrawal ,  Brian T. Kannard ,  Xiaolong Li ,  Bradley C. Liang ,  Rajiv Shah ,  Yuxiang Zhong

IPC: A61M5/172 ,  G05B15/02 ,  G06F19/00

CPC classification number: G16H20/17 ,  A61M5/14244 ,  A61M5/1723 ,  A61M2205/3303 ,  A61M2230/201 ,  G05B15/02 ,  G06F19/00 ,  G06F19/3468

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining a filtered measurement indicative of a physiological condition of a user, determining a metric indicative of a characteristic of the filtered measurement based at least in part on one or more derivative metrics associated with the filtered measurement, and determining an output measurement indicative of the physiological condition of the user based at least in part on the filtered measurement, the metric, and a previous output measurement.

Abstract translation: 提供输液系统，输液装置和相关操作方法。 操作输注装置的示例性方法包括获得指示使用者的生理状况的滤波测量值，至少部分地基于与经滤波测量相关联的一个或多个导数度量来确定指示滤波测量的特性的度量， 以及至少部分地基于经滤波的测量，度量和先前的输出测量来确定指示用户的生理状况的输出测量。

公开(公告)号：US20150316499A1

公开(公告)日：2015-11-05

申请号：US14267739

申请日：2014-05-01

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Steven C. Jacks ,  Raghavendhar Gautham ,  Bradley C. Liang ,  Megan E. Little ,  Daniel E. Pesantez ,  Rajiv Shah

IPC: G01N27/327 ,  C23C28/00 ,  C25D3/52 ,  C25D5/18

CPC classification number: G01N27/416 ,  A61B5/1451 ,  A61B5/14532 ,  A61B2562/02 ,  A61B2562/125 ,  C23C28/00 ,  C25D3/52 ,  C25D3/567 ,  C25D5/18 ,  C25D7/00 ,  G01N27/30 ,  G01N27/327

Abstract: A physiological characteristic sensor, a method for forming a physiological characteristic sensor, and a method for forming a platinum deposit having a rough surface are presented here. The method for forming a physiological characteristic sensor includes immersing a sensor electrode in a platinum electrolytic bath. Further, the method includes performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode and applying a non-pulsed continuous signal to the sensor electrode to form a platinum deposit on the sensor electrode.

Abstract translation: 这里呈现生理特征传感器，形成生理特征传感器的方法和形成具有粗糙表面的铂沉积物的方法。 用于形成生理特征传感器的方法包括将传感器电极浸入铂电解槽中。 此外，该方法包括通过向传感器电极顺序施加脉冲信号并向传感器电极施加非脉冲连续信号以在传感器电极上形成铂沉积物来执行电沉积处理。

公开(公告)号：US20140275899A1

公开(公告)日：2014-09-18

申请号：US14247478

申请日：2014-04-08

Applicant: Medtronic MiniMed, Inc.

Inventor： Rebecca K. Gottlieb ,  Rajiv Shah ,  Eric A. Larson ,  Chia Chiu

IPC: A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/14532 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/6849 ,  C12Q1/006

Abstract: Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.

Abstract translation: 本发明的实施例提供了具有优化的元件和/或元件构造的分析物传感器以及用于制造和使用这种传感器的方法。 本发明的典型实施方案包括用于治疗糖尿病的葡萄糖传感器。

公开(公告)号：US20240345011A1

公开(公告)日：2024-10-17

申请号：US18735347

申请日：2024-06-06

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Keith Nogueira ,  Taly G. Engel ,  Xiaolong Li ,  Bradley C. Liang ,  Rajiv Shah ,  Jaeho Kim ,  Mike C. Liu ,  Andy Y. Tsai ,  Andrea Varsavsky ,  Fei Yu

IPC: G01N27/02 ,  G01N33/487 ,  G01N33/49

CPC classification number: G01N27/026 ,  G01N33/48707 ,  G01N33/49

Abstract: A method of optimizing operation of a glucose sensor includes performing an electrochemical impedance spectroscopy (EIS) procedure to obtain imaginary impedance values for an electrode of a glucose sensor, calculating a change value as a difference between a threshold reference for the imaginary impedance values and a most-recent imaginary impedance value, and obtaining measurements of the calibration factor for the glucose sensor. The method also includes comparing the change value to a first threshold and the calibration factor to a second threshold and determining, based on the comparison, whether sensor data from the glucose sensor is valid.

公开(公告)号：US11974844B2

公开(公告)日：2024-05-07

申请号：US16397156

申请日：2019-04-29

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Keith Nogueira ,  Taly G. Engel ,  Xiaolong Li ,  Bradley C. Liang ,  Rajiv Shah ,  Jaeho Kim ,  Mike C. Liu ,  Andy Y. Tsai

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/7221 ,  A61B5/1451 ,  A61B5/6848 ,  A61B5/6868 ,  A61B5/7225 ,  A61B5/742 ,  A61B2560/0204

Abstract: Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms.

公开(公告)号：US20220262475A1

公开(公告)日：2022-08-18

申请号：US17661674

申请日：2022-05-02

Applicant: Medtronic MiniMed, Inc.

Inventor： Keith Nogueira ,  Pratik J. Agrawal ,  Brian T. Kannard ,  Xiaolong Li ,  Bradley C. Liang ,  Rajiv Shah ,  Yuxiang Zhong

IPC: G16H20/17 ,  A61M5/172 ,  G05B15/02 ,  A61M5/142

Abstract: Disclosed herein are techniques related to adaptive signal processing. The techniques may involve: obtaining a plurality of unfiltered measurement values based on signals generated by a sensor; determining a plurality of filtered measurement values based on the plurality of unfiltered measurement values; determining, based on the plurality of filtered measurements, a first derivative metric for a current filtered measurement of the plurality of filtered measurements and a second derivative metric for the current filtered measurement; determining an output filtered measurement indicative of a physiological condition of a user based at least in part on the current filtered measurement, the first derivative metric, the second derivative metric, and a previous output measurement; and outputting the output filtered measurement.

公开(公告)号：US20220087578A1

公开(公告)日：2022-03-24

申请号：US17542655

申请日：2021-12-06

Applicant: Medtronic MiniMed, Inc.

Inventor： Rajiv Shah ,  Jesper Svenning Kristensen ,  Katherine T. Wolfe ,  Soren Aasmul ,  Anubhuti Bansal

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/1473 ,  G01N21/64 ,  G01N21/77 ,  G01N33/66 ,  A61M5/172

Abstract: A continuous glucose monitoring system may include a hand-held monitor, a transmitter, an insulin pump, and an orthogonally redundant glucose sensor, which may comprise an optical glucose sensor and a non-optical glucose sensor. The former may be a fiber optical sensor, including a competitive glucose binding affinity assay with a glucose analog and a fluorophore-labeled glucose receptor, which is interrogated by an optical interrogating system, e.g., a stacked planar integrated optical system. The non-optical sensor may be an electrochemical sensor having a plurality of electrodes distributed along the length thereof. Proximal portions of the optical and electrochemical sensors may be housed inside the transmitter and operationally coupled with instrumentation for, e.g., receiving signals from the sensors, converting to respective glucose values, and communicating the glucose values. The sensors' distal portions may be inserted into a user's body via a single delivery needle and may be co-located inside the user's body.

公开(公告)号：US11234624B2

公开(公告)日：2022-02-01

申请号：US16185700

申请日：2018-11-09

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Bradley C. Liang ,  Rajiv Shah

IPC: A61B5/1495 ,  G01N27/416 ,  A61B5/00 ,  A61M5/158 ,  A61B5/1486 ,  A61M5/142 ,  A61B5/1459 ,  G01R35/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/0537 ,  G01N33/66 ,  A61M5/172 ,  G01N27/02 ,  A61B5/0538 ,  G01N33/96 ,  G01N33/49

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US10905365B2

公开(公告)日：2021-02-02

申请号：US16171746

申请日：2018-10-26

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Rajiv Shah

IPC: A61B5/1495 ,  A61B5/00 ,  G01R35/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/053 ,  A61B5/1486 ,  G01N33/66 ,  G01N33/49 ,  G01N27/416 ,  A61M5/158 ,  A61M5/142 ,  A61B5/1459 ,  A61M5/172 ,  G01N27/02 ,  G01N33/96

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US20200237268A1

公开(公告)日：2020-07-30

申请号：US16853461

申请日：2020-04-20

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Jenn-Hann Larry Wang ,  Michael E. Miller ,  Raghavendhar Gautham ,  Yiwen Li ,  Rajiv Shah

IPC: A61B5/1495 ,  G01N27/416 ,  A61B5/00 ,  A61M5/158 ,  A61B5/1486 ,  A61M5/142 ,  A61B5/1459 ,  G01R35/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/053 ,  G01N33/66 ,  A61M5/172 ,  G01N27/02 ,  G01N33/96 ,  G01N33/49

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.