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公开(公告)号：US10124090B2
公开(公告)日：2018-11-13
申请号：US14678525
申请日：2015-04-03
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise , Wendy Graczyk
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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公开(公告)号：US20180110527A1
公开(公告)日：2018-04-26
申请号：US15847745
申请日：2017-12-19
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael Constant , Terrance Tran , Joseph Gulachenski
CPC classification number: A61B17/1219 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B17/12168 , A61L31/00 , A61L31/022 , A61L31/041 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/145 , A61L31/146 , A61L2400/04 , C08L71/02
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
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公开(公告)号：US20180085487A1
公开(公告)日：2018-03-29
申请号：US15719197
申请日：2017-09-28
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Xinping Wu , Gloria Hincapie , Yue Wu
IPC: A61L24/00 , A61K31/555 , A61K47/69 , A61K31/4745 , A61L24/06 , C08F220/56
CPC classification number: A61L24/0015 , A61B17/12109 , A61B17/12113 , A61B17/12181 , A61B2017/00004 , A61K31/4745 , A61K31/555 , A61K47/6927 , A61L24/0042 , A61L24/06 , A61L26/0014 , A61L26/0061 , A61L26/009 , A61L31/048 , A61L31/148 , A61L2300/204 , A61L2300/224 , A61L2400/06 , A61L2430/36 , C08F220/56 , C08F236/20 , C08L33/08 , C08L33/10 , C08L33/12 , C08L33/26
Abstract: Described are polymers and methods of forming and using same.
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公开(公告)号：US09724103B2
公开(公告)日：2017-08-08
申请号：US14990676
申请日：2016-01-07
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Terrance Tran
CPC classification number: A61B17/1219 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B17/12168 , A61L31/00 , A61L31/022 , A61L31/041 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/145 , A61L31/146 , A61L2400/04 , C08L71/02
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
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公开(公告)号：US09655989B2
公开(公告)日：2017-05-23
申请号：US14736145
申请日：2015-06-10
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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Patent Agency Ranking
公开(公告)号：US09546236B2
公开(公告)日：2017-01-17
申请号：US14491776
申请日：2014-09-19
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Gloria Hincapie , Clayton Harris
IPC: C08F220/56 , C08F220/38 , C08F222/10 , C08F222/38 , C08F222/40
CPC classification number: C08F220/38 , A61K9/0029 , A61K9/1635 , A61L24/001 , A61L24/06 , A61L31/048 , A61L2430/36 , C08F220/56 , C08F222/1006 , C08F222/385 , C08F2220/382 , C08F2222/408 , Y10T428/2982 , C08L33/08
Abstract: Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.
Abstract translation: 描述了可生物降解的交联聚合物颗粒栓塞及其制备方法。 颗粒栓塞可用作栓塞剂。
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77.发明授权Acrylic hydrogels with deprotonated amine groups that undergo volumetric expansion in response to changes in environmental pH 有权具有脱质子胺基的丙烯酸水凝胶，其响应于环境pH的变化而经历体积膨胀公开(公告)号：US08734834B2
公开(公告)日：2014-05-27
申请号：US13898250
申请日：2013-05-20
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant
IPC: A61F2/02
CPC classification number: C08F22/385 , A61K9/0024 , A61K49/0457 , A61L31/145
Abstract: Hydrogels are described that expand volumetrically in response to a change in their environment and as well as their methods of manufacture and use.
Abstract translation: 水凝胶被描述为响应于其环境的变化以及它们的制造和使用方法而以体积方式膨胀。
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78.发明申请公开(公告)号：US20130274362A1
公开(公告)日：2013-10-17
申请号：US13898250
申请日：2013-05-20
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant
IPC: A61L31/14
CPC classification number: C08F22/385 , A61K9/0024 , A61K49/0457 , A61L31/145
Abstract: Hydrogels are described that expand volumetrically in response to a change in their environment and as well as their methods of manufacture and use.
Abstract translation: 水凝胶被描述为响应于其环境的变化以及它们的制造和使用方法而以体积方式膨胀。
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公开(公告)号：US20130253087A1
公开(公告)日：2013-09-26
申请号：US13899357
申请日：2013-05-21
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Terrance T. Tran
IPC: A61B17/12
CPC classification number: A61B17/12113 , A61B17/12181 , A61B90/39 , A61B2017/00004 , A61B2017/1205 , A61B2090/3966 , A61K49/0404 , A61L24/001 , A61L24/0031 , A61L24/046 , A61L27/16 , A61L27/18 , A61L27/56 , A61L31/048 , A61L31/06 , A61L31/146 , A61L31/18 , A61L2430/36 , C08L39/06 , C08L71/02
Abstract: Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or malformation. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.
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公开(公告)号：US20130131716A1
公开(公告)日：2013-05-23
申请号：US13745258
申请日：2013-01-18
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Terrance Tran
IPC: A61B17/12
CPC classification number: A61B17/1219 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B17/12168 , A61L31/00 , A61L31/022 , A61L31/041 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/145 , A61L31/146 , A61L2400/04 , C08L71/02
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
Abstract translation: 用于闭塞体腔的装置，例如血管动脉瘤栓塞等，以及制造和使用这些装置的方法。 这些装置可以由新颖的膨胀材料，新颖的基础设施设计或两者组成。 所提供的设备是非常灵活的，并且能够对身体组织，导管，空腔等进行减少或不损坏的部署。
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