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公开(公告)号：US20060084152A1
公开(公告)日：2006-04-20
申请号：US11239674
申请日：2005-09-28
摘要： Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MP genes in this organism.
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72.发明申请Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins 审中-公开谷氨酸棒杆菌基因编码应激，抗性和耐受性蛋白质公开(公告)号：US20060078884A1
公开(公告)日：2006-04-13
申请号：US10703799
申请日：2003-11-07
申请人： Markus Pompejus , Burkhard Kroger , Hartwig Schroder , Oskar Zelder , Gregor Haberhauer , Heung-Shick Lee , Hyung-Joon Kim
发明人： Markus Pompejus , Burkhard Kroger , Hartwig Schroder , Oskar Zelder , Gregor Haberhauer , Heung-Shick Lee , Hyung-Joon Kim
CPC分类号： C12P13/04 , C07K14/34 , C07K2319/00 , C12N9/00 , C12N9/18 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
摘要： Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新SRT蛋白的分离的核酸分子，称为SRT核酸分子。 本发明还提供反义核酸分子，含有SRT核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。 本发明还进一步提供了基于该生物体中SRT基因的遗传工程的分离的SRT蛋白，突变的SRT蛋白，融合蛋白，抗原肽以及用于从谷氨酸棒状病毒从谷氨酸棒状杆菌生产所需化合物的方法。
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公开(公告)号：US20050260707A1
公开(公告)日：2005-11-24
申请号：US11055822
申请日：2005-02-11
IPC分类号： G01N33/53 , C07H21/04 , C07K20060101 , C07K14/34 , C12N20060101 , C12N1/15 , C12N1/19 , C12N1/20 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/18 , C12N9/90 , C12N15/09 , C12N15/31 , C12N15/61 , C12N15/74 , C12P20060101 , C12P13/04 , C12P13/08 , C12P21/02 , C12P21/06 , C12Q20060101 , C12Q1/68 , C12R1/15 , G01N33/566 , G01N33/569
CPC分类号： C12N9/18 , C07K14/34 , C12N9/00 , C12N9/1096 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/24 , C12Y206/01005
摘要： Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MP genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MP蛋白的分离的核酸分子，称为MP核酸分子。 本发明还提供反义核酸分子，含有MP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。 本发明还进一步提供分离的MP蛋白，突变的MP蛋白，融合蛋白，抗原肽和用于基于该生物体中MP基因的遗传工程改进谷氨酸棒球菌产生所需化合物的方法。
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74.发明申请公开(公告)号：US20050191733A1
公开(公告)日：2005-09-01
申请号：US11061298
申请日：2005-02-17
IPC分类号： C07H21/04 , C12N1/12 , C12N1/20 , C12N1/21 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/00 , C12N15/74 , C12P1/04 , C12P13/04 , C12P21/06
CPC分类号： C12N9/1205 , C07K14/34 , C12N9/00 , C12N9/1223 , C12P1/04 , C12P13/04 , C12R1/15 , C12Y207/01069
摘要： Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of PTS genes in this organism.
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75.发明申请公开(公告)号：US20070231259A1
公开(公告)日：2007-10-04
申请号：US11505101
申请日：2006-08-15
CPC分类号： C12N9/18 , C07K14/34 , C07K2319/00 , C12N9/00 , C12N9/90 , C12P7/18 , C12P7/40 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24 , C12P19/00 , C12P19/34 , C12Y301/01031
摘要： Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SMP proteins, mutated SMP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SMP genes in this organism.
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公开(公告)号：US20070099213A1
公开(公告)日：2007-05-03
申请号：US11507097
申请日：2006-08-17
CPC分类号： C07K14/34 , C07H21/02 , C07H21/04 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
摘要： Isolated nucleic acid molecules, designated MCP nucleic acid molecules, which encode novel MCP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MCP proteins, mutated MCP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MCP genes in this organism.
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公开(公告)号：US20070042474A1
公开(公告)日：2007-02-22
申请号：US11092052
申请日：2005-03-28
CPC分类号： C07K14/34 , C07H21/02 , C07H21/04 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
摘要： Isolated nucleic acid molecules, designated MCP nucleic acid molecules, which encode novel MCP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MCP proteins, mutated MCP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MCP genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MCP蛋白质的分离的核酸分子，命名为MCP核酸分子。 本发明还提供反义核酸分子，含有MCP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。 本发明还进一步提供了分离的MCP蛋白，突变的MCP蛋白，融合蛋白，抗原肽和用于根据该生物体中MCP基因的遗传工程改进从谷氨酸棒球菌生产所需化合物的方法。
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78.发明申请公开(公告)号：US20050277115A1
公开(公告)日：2005-12-15
申请号：US10454437
申请日：2003-06-04
摘要： Isolated nucleic acid molecules, designated HA nucleic acid molecules, which encode novel HA proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HA nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated HA proteins, mutated HA proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of HA genes in this organism.
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公开(公告)号：US20050153402A1
公开(公告)日：2005-07-14
申请号：US11006098
申请日：2004-12-06
IPC分类号： C07K14/34 , C12N9/00 , C12N9/18 , C12N9/90 , C12P13/04 , C07H21/04 , C12N1/21 , C12N15/74 , C12Q1/68
CPC分类号： C12P7/6472 , C07K14/34 , C07K2319/00 , C12N9/00 , C12N9/18 , C12N9/90 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P13/04 , C12P17/10
摘要： Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MR proteins, mutated MR proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MR genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MR蛋白质的分离的核酸分子，命名为MR核酸分子。 本发明还提供反义核酸分子，含有MR核酸分子的重组表达载体和已经引入表达载体的宿主细胞。 本发明还进一步提供了分离的MR蛋白，突变的MR蛋白，融合蛋白，抗原肽以及用于基于该生物体中MR基因的遗传工程改进谷氨酸棒球菌的所需化合物生产的方法。
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公开(公告)号：US20050014235A1
公开(公告)日：2005-01-20
申请号：US10495291
申请日：2002-11-11
申请人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corrina Klopprogge , Gregor Haberhauer
发明人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corrina Klopprogge , Gregor Haberhauer
CPC分类号： C12N9/0006 , C07K14/415
摘要： Isolated nucleic acid molecule, coding for a polypeptide having the amino acid sequence referred to in each case in Table 1/column 2, wherein the nucleic acid molecule in the amino acid position indicated in Table 1/column 4 encodes a proteinogenic amino acid different from the particular amino acid indicated in Table 1/column 5 in the same row.
摘要翻译： 分离的核酸分子，编码具有表1 /栏2中各种情况的氨基酸序列的多肽，其中表1 /第4列所示氨基酸位置的核酸分子编码不同于 在同一行的表1 /列5中所示的特定氨基酸。
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