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90 条记录 (耗时 0.035 秒)

    Preparation for the prophylaxis of restenosis
    71.
    发明授权
    Preparation for the prophylaxis of restenosis 有权
    准备预防再狭窄

    公开(公告)号：US07750041B2

    公开(公告)日：2010-07-06

    申请号：US10472844

    申请日：2001-12-20

    申请人： Ulrich Speck ,  Brunn Scheller

    发明人： Ulrich Speck ,  Brunn Scheller

    IPC分类号： A61K31/337 ,  A61K31/517 ,  A61K2/02 ,  A61K31/00

    CPC分类号： A61L29/08 ,  A61K9/0019 ,  A61K9/5094 ,  A61K31/095 ,  A61K31/165 ,  A61K31/337 ,  A61K45/06 ,  A61K49/0433 ,  A61K49/0438 ,  A61K49/0447 ,  A61K49/0452 ,  A61K49/105 ,  A61K49/106 ,  A61K49/18 ,  A61L29/16 ,  A61L29/18 ,  A61L31/16 ,  A61L2300/416 ,  A61K2300/00

    摘要： The invention relates to a preparation for restenosis prevention. The preparations for restenosis prevention known as yet do not reach sufficient active agent concentrations in the affected sections of the vascular walls as higher doses cause undesirable side effects. The present invention is a preparation to which at least one antihyperplastic agent is added that has a distribution ratio between butanol and water ≧0.5. The lipophilic active agent is absorbed by the vascular wall fast and in sufficient quantity. The preparation may be a liquid that can pass through capillaries and may contain a contrast agent so that the active agent is transferred into the vascular wall without any additional effort while the usually required contrast radiograms are taken. The preparation may also be applied to a catheter.

    摘要翻译： 本发明涉及预防再狭窄的制剂。 已知的再狭窄预防制剂在血管壁的受影响部分中不能达到足够的活性剂浓度，因为较高剂量引起不期望的副作用。 本发明是一种具有至少一种抗高血压剂的制剂，其具有丁醇和水之间的分配比≥0.5。 亲脂性活性剂被血管壁快速且足够的量吸收。 该制剂可以是可以通过毛细血管并且可以含有造影剂的液体，使得活性剂在没有任何额外的努力的同时转移到血管壁中，而通常需要的对比度放射照相。 该制剂也可以应用于导管。

    Sterile tissue access system
    76.
    发明授权
    Sterile tissue access system 失效
    无菌组织接种系统

    公开(公告)号：US06899708B2

    公开(公告)日：2005-05-31

    申请号：US10250699

    申请日：2002-01-04

    申请人： Ulrich Speck ,  Norbert Hosten ,  Goran Lukic

    发明人： Ulrich Speck ,  Norbert Hosten ,  Goran Lukic

    IPC分类号： A61B18/00 ,  A61N5/06 ,  A61B18/24

    CPC分类号： A61N5/0601 ,  A61B2018/00029

    摘要： A tissue access system for tissue ablation without open surgery includes a distally open elongated tube (4) with a handle piece (6) having a through channel (7) in axial alignment with the elongated tube and an infusion fitting (9) that opens into the through channel for supplying a liquid or gaseous medium. An energy guide (16) or a catheter (10) housing such energy guide is arranged in the elongated tube and sealed from the outside. An energy-releasing zone of the energy guide is located in an energy-transparent section of the elongated tube. The medium, introduced into an annular flow channel between the energy guide or catheter and the elongated tube, serves as coolant for the energy-releasing zone and as heat transport medium in the tissue, and can also function as an ablation agent and as a contrast agent for inspection using imaging techniques.

    摘要翻译： 没有开放手术的用于组织消融的组织存取系统包括具有手柄片（6）的远端开放的细长管（4），所述手柄件具有与所述细长管轴向对准的通道（7）和通向所述导管 用于供应液体或气体介质的通道。 容纳这种能量引导件的能量引导件（16）或导管（10）布置在细长管中并从外部密封。 能量引导件的能量释放区位于细长管的能量透明部分中。 引入能量引导件或导管与细长管之间的环形流动通道的介质用作用于能量释放区的冷却剂，并且用作组织中的热传输介质，并且还可用作消融剂和作为对比 使用成像技术检查的代理。

    Fluid-containing plastic disposable syringe that is to be sterilized and a process for filling and sealing same
    80.
    发明授权
    Fluid-containing plastic disposable syringe that is to be sterilized and a process for filling and sealing same 失效
    要进行灭菌的含流体的塑料一次性注射器和用于填充和密封的过程

    公开(公告)号：US6129711A

    公开(公告)日：2000-10-10

    申请号：US817758

    申请日：1997-06-19

    申请人： Ulrich Speck

    发明人： Ulrich Speck

    IPC分类号： A61M5/00 ,  A61M5/28 ,  A61M5/31 ,  A61M5/315 ,  A61M5/32 ,  A61M5/34 ,  B65B3/00

    CPC分类号： A61M5/34 ,  A61M5/28 ,  A61M5/315 ,  B65B3/003 ,  A61M2005/3104 ,  A61M2005/3118 ,  A61M2005/3139 ,  A61M2005/3279 ,  A61M2207/00 ,  A61M5/001 ,  A61M5/1782 ,  A61M5/3134 ,  A61M5/31505 ,  A61M5/32

    摘要： A process for filling and sealing a fluid-containing plastic disposable syringe that is to be sterilized, wherein the disposable syringe includes a barrel having a front end, a nozzle part having a sealing element, a plunger plug, and a plunger stop element that is placed in the area of a cylinder gripping plate, the process includes inserting and pushing the plunger plug into the front end of the barrel, using pressure and forcing a fluid medium into the barrel via the nozzle part, whereby the fluid medium pushes the plunger plug in the direction of the plunger stop element, and sealing the sealing element of the nozzle part by plastic deformation after the barrel and the nozzle part are filled.

    摘要翻译： PCT No.PCT / DE95 / 01523 Sec。 371日期：1997年6月19日 102（e）日期1996年6月19日PCT提交1995年10月27日PCT公布。 公开号WO96 / 13289 日期1996年5月9日一种用于填充和密封待灭菌的含流体的塑料一次性注射器的方法，其中一次性注射器包括具有前端的筒，具有密封元件的喷嘴部分，柱塞塞和柱塞 该止动元件被放置在气缸夹持板的区域中，该过程包括使用压力将柱塞塞插入并推压到桶的前端，并通过喷嘴部分迫使流体介质进入筒体，由此流体介质 沿柱塞止动件的方向推动柱塞塞，并且在筒体和喷嘴部件被填充之后通过塑性变形来密封喷嘴部件的密封元件。