摘要:
The invention describes a novel test structure and process to create the structure for performing automatic dynamic stress testing of PMOS devices for Negative Bias Temperature Instability (NB TI). The invention consists of an integrated inverter, two integrated electronic switches for switching from stress mode to device DC characterization measurement mode, and a PMOS FET device under test (DUT). The inverter assures the proper 180 degree phase relationship between the test device source and gate voltage while the imbedded electronic switches provide isolation of the test device during DC characterization testing. Another embodiment of the invention enables the testing of multiple devices under test (DUTs).
摘要:
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
摘要翻译:包含SEQ ID NO:2的氨基酸序列的IL-1β结合抗体或IL-1β结合片段,以及相关的核酸,载体,细胞和组合物,以及其用于治疗或预防疾病的方法 以及制备亲和力成熟的IL-1β结合多肽的方法。 提供具有期望的亲和力和效力的IL-1β结合抗体或其IL-1β结合片段。
摘要:
An optical device includes an input optical source that provides and optical signal to the optical device. A surface phonon polariton (SPP) nanostructure receives the optical signal that interacts with the SPP nanostructure to excite a Raman process and produce a Raman light signal. The Raman light signal comprises a broad spectral range from near infrared to far infrared.
摘要:
A photovoltaic device comprises: a first cladding material; a photosensitive material having an index of refraction larger than the first cladding material index of refraction, the photosensitive material disposed adjacent the first cladding material; and a second cladding material having an index of refraction smaller than the photosensitive material index of refraction, the photosensitive material disposed between the first cladding material and the second cladding material so as to form a waveguide for confining propagating photons; and first and second electrodes in electrical contact with the photosensitive material.
摘要:
A method of detecting and isolating cells that produce any secreted protein of interest (POI), comprising: a) constructing a cell line transiently or stably expressing a cell surface capture molecule, which binds the POI, by transfecting the cell line with a nucleic acid that encodes such cell surface capture molecule; b) transfecting said cell simultaneously or subsequently with a second nucleic acid that encodes a POI wherein such POI is secreted; c) detecting the surface-displayed POI by contacting the cells with a detection molecule, which binds the POI; and d) isolating cells based on the detection molecule.
摘要:
Systems and methods are presented for real-time realistic river modeling. In one implementation, when provided with the physical features of a modeled terrain, the systems and methods described herein automatically determine a watercourse route in relation to the terrain and calculate river borders. The systems and methods then calculate a surface structure for the river between the borders and map texture coordinates to the surface structure. The systems and methods apply textures at the texture coordinates to provide an animated, view-dependent representation of wave geometries for the modeled water surface including reflection, refraction, and Fresnel effects.
摘要:
A method for effecting a kickdown shift in a transmission of an automotive vehicle controls turbine speed change based on a continuous desired acceleration calculation. The method determines an initial speed of a turbine that transmits torque between an engine and a plurality of gears through a plurality of releasing and engaging elements. A target speed of one of the plurality of gears is determined. A desired time required to increase the turbine speed to the target speed is determined. A desired acceleration of the turbine is calculated according to the initial speed, the target speed, and the desired time. Turbine speed change rate is controlled through controlling the clutch torque of one or more of the releasing and engaging elements based on the desired acceleration.
摘要:
A transmission control system includes a first gear engagement element that receives fluid and engages a first gear. An electromagnetic actuator selectively interrupts fluid flow to the first gear engagement element based on a duty cycle of a control signal. A control module adjusts the duty cycle so that a fluid flow rate continuously decreases as the first gear engagement element produces a first torque sufficient to hold the first gear. The flow rate is based on a first estimated volume of the fluid necessary for the first gear engagement element to produce the first torque. The control module computes a current volume of the fluid when the first gear engagement element produces the first torque. The control module adjusts a value of the first estimated volume for subsequent transmission control when a difference between the current volume and the first estimated volume is greater than a predetermined volume.
摘要:
The present invention provides bipyrimidinyl diphosphine compounds of the formula wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R′ and R″ are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; or an enantiomer thereof; or an enantiomeric mixture thereof. The compounds of the formula (I) are chiral atropisomeric bipyrimidinyl diphosphine compounds and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions, e.g., in palladium catalyzed asymmetric allylic substitution reactions. The compounds of the present invention are easily accessible in high enantiomeric purity according to the methods disclosed herein.
摘要:
Techniques for producing a glass structure having interconnected macroscopic pores, including providing a polymeric structure having interconnected macroscopic pores; providing polymerizable glass precursors; filling pores in the polymeric structure with the polymerizable glass precursors; polymerizing the polymerizable glass precursors to yield a filled polymeric structure; and decomposing the filled polymeric structure to produce a glass structure having interconnected macroscopic pores. Techniques for filling pores of such glass structure with a material having a high refractive index, and for then removing the glass structure. Structures can be produced having interconnected macroscopic pores and high refractive index contrasts, which can be used, for example, as photonic band gaps.