摘要:
A hybrid nanotube, high-performance, dynamically reconfigurable architecture, NATURE, is provided, and a design optimization flow method and system, NanoMap. A run-time reconfigurable architecture is provided by associating a non-volatile universal memory to each logic element to enable cycle-by-cycle reconfiguration and logic folding, while remaining CMOS compatible. Through logic folding, significant logic density improvement and flexibility in performing area-delay tradeoffs are possible. NanoMap incorporates temporal logic folding during the logic mapping, temporal clustering and placement steps. NanoMap provides for automatic selection of a best folding level, and uses force-direct scheduling to balance resources across folding stages. Mapping can thereby target various optimization objectives and user constraints. A high-density, high-speed carbon nanotube RAM can be implemented as the universal memory, allowing on-chip multi-context configuration storage, enabling fine-grain temporal logic folding, and providing a significant increase in relative logic density.
摘要:
Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided.
摘要:
A method and system for extracting coronary vessels fluoroscopic image sequences using coronary digital subtraction angiography (DSA) are disclosed. A set of mask images of a coronary region is received, and a sequence of contrast images for the coronary region is received. For each contrast image, vessel regions are detected in the contrast image using learning-based vessel segment detection and a background region of the contrast image is determined based on the detected vessel regions. Background motion is estimated between one of the mask images and the background region of the contrast image, and the mask image is warped based on the estimated background motion to generate an estimated background layer. The estimated background layer is subtracted from the contrast image to extract a coronary vessel layer for the contrast image.
摘要:
For cognitive radio systems, the transmit power of a cognitive radio device is controlled so that the cognitive, unlicensed radio device does not interfere with the use of a shared spectrum by a primary, licensed device. Controlling the transmit power includes determining a distance, or a function of the distance, between a primary transmitter of the primary device and the cognitive radio device based on sensing information from a spectrum sensing process. The maximum transmit power of the cognitive radio device is then dynamically controlled based on the distance, or the function of the distance, while considering a worst case scenario of an underlying cognitive radio model, to guarantee a quality of service requirement of the primary device.
摘要:
A magnetic element includes a pinned layer, a nonferromagnetic spacer layer, and a free layer. The nonferromagnetic spacer layer resides between the pinned layer and the free layer. The free layer has a track width of not more than 0.08 micron.
摘要:
The present invention relates generally to organic chemistry, biochemistry, pharmacology and medicine. More particularly, it relates to 3-benzylidene-indolin-2-one derivatives and their physiologically acceptable salts and prodrugs which modulate the activity of protein kinases (“PKs”), especially protein tyrosine kinase, and, therefore, are expected to exhibit a salutary effect against disorders related to abnormal PK activity. The present invention is further directed to methods of using of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of protein kinase-mediated diseases and disorders, such as cancer.
摘要:
The invention relates to novel polymers or oligomers containing at least sulfinate groups (P—(SO2)nX, X=1-(n=1), 2-(n=2) or 3-(n=3) valent metal cation or H+ or ammonium ion NR4+ where R=alkyl, aryl, H), which are obtained by completely or partially reducing polymers or oligomers containing at least SO2Y-groups (Y═F, Cl, Br, I, OR, NR2 (R=alkyl and/or aryl and/or H), N-imidazolyl, N-pyrazolyl) by means of suitable reducing agents in a suspension or in a solution form.Polymer and polymer(blend)membranes which are obtained by further reacting the received sulfinated polymers, especially by alkylation of the sulfinate groups with mono- di- or oligo functional electrophiles. The invention further relates to methods for producing the sulfinated polymers and for further reacting the sulfinated polymers with electrophiles by S-alkylation.
摘要:
The linear vibrator includes a base forming a hollow space, a suspension fixed on the base, and an oscillating portion suspended in the hollow space by the suspension. The suspension defines a flat part, a connecting portion bent downward from the flat part, and a spring portion extended horizontally in a direction parallel to flat part from the end of the connecting portion. The suspension is directly connected with the outside component, thereby transmitting the vibration to the outside component rapidly.
摘要:
Imaging agents of formulas (I)-(V) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formulas (I)-(V) capable of binding to tau proteins and β-amyloid peptides are presented herein. The invention also relates to methods of imaging Aβ and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formulas (I)-(V) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders.