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    Detection of Stenosis
    71.
    发明申请
    Detection of Stenosis 审中-公开
    狭窄检测

    公开(公告)号：US20080139951A1

    公开(公告)日：2008-06-12

    申请号：US11608578

    申请日：2006-12-08

    申请人： Abhilash Patangay ,  Marina Brockway ,  Jeffrey E. Stahmann ,  Yi Zhang ,  Gerrard M. Carlson

    发明人： Abhilash Patangay ,  Marina Brockway ,  Jeffrey E. Stahmann ,  Yi Zhang ,  Gerrard M. Carlson

    IPC分类号： A61B5/026 ,  A61F2/82

    CPC分类号： A61B5/411 ,  A61B5/0031 ,  A61B5/02007 ,  A61B5/02158 ,  A61B5/026 ,  A61B5/0402 ,  A61B5/076 ,  A61B2562/0204 ,  A61B2562/0219 ,  A61F2/02 ,  A61F2/91 ,  A61F2250/0002

    摘要： A system for detecting stenosis in a patient. The system includes an implantable sensing unit having a turbulence sensor and a communication device for transmitting a signal from the turbulence sensor. The system also includes a cardiac sensor for generating a signal corresponding to cardiac activity and a processing device configured to receive signals from the sensing unit and from the cardiac sensor. The processing device is configured to determine a time window corresponding to cardiac activity, to determine a turbulence level from the turbulence signal within the time window, and to detect the presence of stenosis from the turbulence level.

    摘要翻译： 一种用于检测患者狭窄的系统。 该系统包括具有湍流传感器的可植入感测单元和用于从湍流传感器发送信号的通信装置。 该系统还包括用于产生对应于心​​脏活动的信号的心脏传感器和被配置为从感测单元和心脏传感器接收信号的处理装置。 处理装置被配置为确定对应于心脏活动的时间窗口，以确定在时间窗口内的湍流信号的湍流水平，并且从湍流水平检测狭窄的存在。

    Method and system for remote hemodynamic monitoring
    72.
    发明申请
    Method and system for remote hemodynamic monitoring 审中-公开
    远程血液动力学监测方法与系统

    公开(公告)号：US20080097227A1

    公开(公告)日：2008-04-24

    申请号：US11881809

    申请日：2007-07-27

    申请人： Mark Zdeblick ,  Joseph Ruggio

    发明人： Mark Zdeblick ,  Joseph Ruggio

    IPC分类号： A61B5/0215

    CPC分类号： A61B5/0205 ,  A61B5/02028 ,  A61B5/02158 ,  A61B5/029 ,  A61B5/1107 ,  A61B5/1473 ,  A61B5/6882 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/36585 ,  A61N1/3684 ,  A61N1/3702

    摘要： A cardiac sensor system includes implanted cardiac sensor assemblies and an external controller which receives information from the implanted sensors. The sensors permit direct measurement of a number of physiologic parameters. The external controller permits calculation of a variety of performance values based on the measured physiological parameters. Optionally, patient oxygen consumption can be measured externally and combined with the internally measured physiologic parameters in order to calculate a variety of unique performance values.

    摘要翻译： 心脏传感器系统包括植入的心脏传感器组件和从植入的传感器接收信息的外部控制器。 传感器允许直接测量多个生理参数。 外部控制器允许基于测量的生理参数计算各种性能值。 任选地，可以外部测量患者的氧气消耗量并结合内部测量的生理参数，以便计算各种独特的性能值。

    Methods and systems for measuring cardiac parameters
    73.
    发明申请
    Methods and systems for measuring cardiac parameters 审中-公开
    测量心脏参数的方法和系统

    公开(公告)号：US20070161914A1

    公开(公告)日：2007-07-12

    申请号：US11636404

    申请日：2006-12-08

    申请人： Mark Zdeblick ,  Joseph Ruggio

    发明人： Mark Zdeblick ,  Joseph Ruggio

    IPC分类号： A61B5/02

    CPC分类号： A61B5/0205 ,  A61B5/02028 ,  A61B5/02158 ,  A61B5/029 ,  A61B5/1107 ,  A61B5/1473 ,  A61B5/6882

    摘要： Methods and systems of the present invention provide for measurement of various cardiac parameters. Methods generally involve causing a change in volume and/or pressure in a heart chamber, measuring the change, and calculating at least one cardiac parameter based on the change. Systems typically include at least one actuator, at least one sensor, and a catheter or other device for positioning at least partially in a heart chamber. In some embodiments, the system may also include a controller, such as a computer or other processor, an external actuator, an external sensor, and/or an ECG device. Methods and systems of the invention may be used to more accurately diagnose cardiac conditions in order to make more informed treatment decisions.

    摘要翻译： 本发明的方法和系统提供各种心脏参数的测量。 方法通常包括引起心室中体积和/或压力的变化，测量变化，以及基于变化计算至少一个心脏参数。 系统通常包括至少一个致动器，至少一个传感器，以及用于至少部分地定位在心室中的导管或其它装置。 在一些实施例中，系统还可以包括诸如计算机或其他处理器的控制器，外部致动器，外部传感器和/或ECG设备。 可以使用本发明的方法和系统来更准确地诊断心脏病状，以便做出更明智的治疗决定。

    Method and apparatus for enhancing cardiac pacing
    74.
    发明授权
    Method and apparatus for enhancing cardiac pacing 有权
    用于增强心脏起搏的方法和装置

    公开(公告)号：US07200439B2

    公开(公告)日：2007-04-03

    申请号：US10764429

    申请日：2004-01-23

    申请人： Mark Zdeblick ,  Joseph M. Ruggio

    发明人： Mark Zdeblick ,  Joseph M. Ruggio

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365 ,  A61B5/02028 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/02158 ,  A61B5/026 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/1459 ,  A61B5/6883 ,  A61N1/3627 ,  A61N1/36528 ,  A61N1/3655 ,  A61N1/36557 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36585 ,  A61N1/3682 ,  A61N1/3684

    摘要： Methods, apparatus and systems for enhancing cardiac pacing generally provide for measuring at least one cardiac characteristic, calculating at least one cardiac performance parameter based on the measured characteristic(s), and adjusting at least one functional parameter of a cardiac pacing device. Devices may include at least one catheter (such as a multiplexed catheter with one or more sensors and/or actuators), at least one implant (such as a sensor implantable in a heart wall), or a combination of both. Various cardiac performance parameters and/or pacing device performance parameters may be weighted, and the parameters and their respective weights may be used to determine one or more adjustments to be made to the pacing device. In some instances, the adjustments are made automatically.

    摘要翻译： 用于增强心脏起搏的方法，装置和系统通常提供测量至少一个心脏特征，基于所测量的特征来计算至少一个心脏性能参数，以及调整心脏起搏装置的至少一个功能参数。 装置可以包括至少一个导管（例如具有一个或多个传感器和/或致动器的多路导管），至少一个植入物（例如可植入心脏壁的传感器）或两者的组合。 可以对各种心脏性能参数和/或起搏装置性能参数进行加权，并且可以使用参数及其各自的权重来确定对起搏装置进行的一项或多项调整。 在某些情况下，会自动进行调整。

    Sensing device and method for measuring features in a fluid
    75.
    发明授权
    Sensing device and method for measuring features in a fluid 失效
    用于测量流体特征的感测装置和方法

    公开(公告)号：US06938474B2

    公开(公告)日：2005-09-06

    申请号：US10240089

    申请日：2001-03-22

    申请人： Patrik Melvås

    发明人： Patrik Melvås

    IPC分类号： A61B5/0215 ,  A61B5/026 ,  G01D21/02 ,  G01K1/04 ,  G01L19/00 ,  G01F1/68

    CPC分类号： G01L19/0092 ,  A61B5/02158 ,  A61B5/026 ,  G01D21/02 ,  G01K1/045

    摘要： A method and a device for measuring features in a fluid such as pressure, flow rate, and temperature measurements is disclosed. The sensing device includes at least two sensing elements, all of which are mounted and/or fabricated on a chip and connected to a chip circuit, and a power supply and measuring circuit placed outside the chip and connected to the chip circuit. According to the invention the power supply and measuring circuit is controllable to feed at least two different kinds of signaling to the chip circuit. Furthermore the sensing elements are connected to each other and to the power supply and measuring circuit such that at least one of the sensing elements, controllable by the signaling from the power supply, can be individually measured. The chip is adapted to be mounted on a catheter or a guide wire.

    摘要翻译： 公开了用于测量流体中的特征的方法和装置，例如压力，流速和温度测量。 感测装置包括至少两个感测元件，它们都被安装和/或制造在芯片上并连接到芯片电路，以及放置在芯片外部并连接到芯片电路的电源和测量电路。 根据本发明，电源和测量电路是可控的，以将至少两种不同类型的信令馈送到芯片电路。 此外，感测元件彼此连接并且连接到电源和测量电路，使得可以单独测量通过来自电源的信令可控的感测元件中的至少一个。 芯片适于安装在导管或导丝上。

    Implantable device for monitoring aneurysm sac parameters
    76.
    发明授权
    Implantable device for monitoring aneurysm sac parameters 失效
    用于监测动脉瘤囊参数的植入式装置

    公开(公告)号：US06890303B2

    公开(公告)日：2005-05-10

    申请号：US10116782

    申请日：2002-04-04

    申请人： Matthew Joseph Fitz

    发明人： Matthew Joseph Fitz

    IPC分类号： A61B5/00 ,  A61B5/0215 ,  A61B5/07

    CPC分类号： A61B5/02014 ,  A61B5/0031 ,  A61B5/02158 ,  A61B5/076 ,  A61B2560/0257

    摘要： A device for measuring physiological parameters within an aneurysm sac that has been excluded from blood flow by an endoprosthesis. The device is comprised of at least two sensors, one placed in the aneurysm sac and another in a systemic artery. A differential between the readings of the two sensors can then be calculated, making the device easily calibrated in vivo and insensitive to changes in atmospheric pressure.

    摘要翻译： 一种用于测量动脉瘤囊内的生理参数的装置，其通过内置假体排除在血流之外。 该装置由至少两个传感器组成，一个放置在动脉瘤囊中，另一个位于全身动脉中。 然后可以计算两个传感器的读数之间的差异，使得器件容易在体内校准，并且对大气压力的变化不敏感。

    Implantable acoustic bio-sensing system and method
    77.
    发明授权
    Implantable acoustic bio-sensing system and method 有权
    植入式声学生物传感系统及方法

    公开(公告)号：US06432050B1

    公开(公告)日：2002-08-13

    申请号：US09303644

    申请日：1999-05-03

    申请人： Yariv Porat ,  Avi Penner ,  Eyal Doron

    发明人： Yariv Porat ,  Avi Penner ,  Eyal Doron

    IPC分类号： A61B500

    CPC分类号： A61B5/02158 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/031 ,  A61B5/413 ,  A61B2562/028 ,  A61M2205/3523 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1138 ,  H04R17/00

    摘要： An implantable biosensor system for monitoring and optionally alleviating a physiological condition in a patient is provided and includes (a) at least one sensor for sensing at least one parameter of a physiological condition and for generating electrical sensor signals representative of the physiological condition; and (b) a first acoustic activatable transducer being directly or indirectly coupled with the at least one sensor, the first acoustic activatable transducer being for converting a received acoustic interrogation signal from outside the patient's body into an electrical power for energizing the processor, the first acoustic activatable transducer further being for converting the electrical sensor signals of the at least one sensor into acoustic signals receivable out of the patient's body, such that information pertaining to the at least one parameter of the physiological condition can be relayed outside the patient's body upon generation of an acoustic interrogation signal.

    摘要翻译： 提供了一种用于监测和任选地减轻患者生理状况的植入式生物传感器系统，其包括（a）至少一个用于感测至少一个生理状态参数并用于产生代表生理状态的电传感器信号的传感器; 所述第一声学可激活换能器用于将接收到的来自患者身体外部的声学询问信号转换成用于激励所述处理器的电力，所述第一声学可激活换能器与所述至少一个传感器直接或间接耦合， 声学可激活的换能器还用于将至少一个传感器的电传感器信号转换成可从患者身体接收的声信号，使得与生理状况的至少一个参数相关的信息可以在生成后被中继到患者体外 的声讯讯号。

    Heart failure monitor quicklook summary for patient management systems
    78.
    发明申请
    Heart failure monitor quicklook summary for patient management systems 有权
    心力衰竭监测器病人管理系统的概要

    公开(公告)号：US20010025137A1

    公开(公告)日：2001-09-27

    申请号：US09809915

    申请日：2001-03-16

    发明人： James D. Webb ,  Tom Dean Bennett

    IPC分类号： A61B005/00

    CPC分类号： A61B5/0031 ,  A61B5/02055 ,  A61B5/02158 ,  G06F19/00

    摘要： Continuous remote monitoring of patients based on data obtained from an implantable hemodynamic monitor provides an interactive patient management system. Using network systems, patients are remotely monitored to continuously diagnose and treat heart-failure conditions. A screen displayable summary provides continuous feedback and information to physicians, patients and authorized third parties. The quick look summary includes various sites and presentation tailored to match the patients' and physicians' needs. The quick look summary further includes intelligent features that understand and retain the user's interests, preferences and use patterns. Patients, physicians and other caregivers are seamlessly connected to monitor and serve the chronic needs of heart-failure patients in a reliable and economic manner.

    摘要翻译： 基于从可植入血液动力学监测器获得的数据对患者的连续远程监测提供了交互式患者管理系统。 使用网络系统，对患者进行远程监控，以不断诊断和治疗心力衰竭状况。 屏幕可显示的摘要为医生，患者和授权的第三方提供持续的反馈和信息。 快速查看摘要包括各种网站和演示文稿，以满足患者和医生的需求。 快速概述进一步包括了解和保留用户兴趣，偏好和使用模式的智能功能。 患者，医生和其他照顾者无缝连接，以可靠和经济的方式监测和服务于心力衰竭患者的长期需求。