公开(公告)号：US20170341079A1

公开(公告)日：2017-11-30

申请号：US15162837

申请日：2016-05-24

申请人： Taj King

发明人： Taj King

IPC分类号： B01L9/06 ,  B04B15/00

CPC分类号： B01L9/06 ,  B01L2200/025 ,  B01L2200/087 ,  B01L2300/028 ,  B01L2300/0809 ,  B01L2300/0848 ,  B01L2300/12 ,  B01L2300/1894 ,  B04B15/00

摘要： A centrifuge tube holding assembly includes a body having a front side, a back side, a top edge, a bottom edge, a first lateral edge and a second lateral edge. The top edge has a plurality of apertures extending downwardly therein and each of the apertures may be used for removably receiving an ultracentrifuge tube. The front wall has an opening therein for viewing an open space positioned below the top edge. A panel is positioned over the opening. The panel is transparent to allow viewing through the panel.The panel has measurement indicia thereon configured to be positioned to be alignable with the ultracentrifuge tube.

公开(公告)号：US09651412B2

公开(公告)日：2017-05-16

申请号：US13982742

申请日：2012-01-31

申请人： Elmar Swiegot ,  Alan Shinn ,  Chiko Fan ,  David King ,  Elias Elias

发明人： Elmar Swiegot ,  Alan Shinn ,  Chiko Fan ,  David King ,  Elias Elias

IPC分类号： B67D1/00 ,  G01F11/02 ,  B01L3/02

CPC分类号： G01F11/023 ,  B01L3/0206 ,  B01L3/0217 ,  B01L2300/028 ,  G01F11/021 ,  G01F11/025

摘要： The invention relates to a dosing device for dispensing and/or receiving a dosed amount of a liquid, comprising a piston device being disposed in a housing and a device for determining the stroke of the piston and/or the position of the piston, wherein the device for determining the stroke of the piston and/or the position of the piston features at least one scalar element and at least one measuring device, wherein the scalar element is fixedly disposed at the housing of the piston device and the measuring device is directly or indirectly connected to the piston and can be moved together with the piston, or wherein the scalar element is disposed at the piston so as to be movable with the piston and the measuring device is fixedly disposed at the housing, and wherein the scalar element is designed as an absolutely coded scale.

公开(公告)号：US20170087546A1

公开(公告)日：2017-03-30

申请号：US15375767

申请日：2016-12-12

申请人： Forward Biotech, Inc.

发明人： Ian K. Glasgow ,  Brian Kolb ,  Andrea Habura

IPC分类号： B01L3/02 ,  G01F17/00 ,  G01F25/00

CPC分类号： B01L3/0293 ,  B01L3/5027 ,  B01L2200/148 ,  B01L2300/028 ,  B01L2300/0838 ,  B01L2400/0406 ,  G01F17/00 ,  G01F25/0084 ,  G01F25/0092

摘要： A measurement device containing one or more capillaries to measure the volume of a dispensed fluid and determine the volumetric accuracy of the dispensing device. The measurement device can contain a reservoir containing the fluid to be measured and there may be an additional reservoir for a secondary fluid. A viewing window is necessary to complete a manual measurement and may include a magnifying lens. The liquid well by the capillary inlet may be shaped such that the measurement fluid is directed toward the capillary. The well may have features designed to position the dispensing device toward the capillary, or to position the well proximal to the capillary after it is filled. The well may also have surfaces or coatings which attract or do not attract various types of substances. The measurement device may interface with sensors to output measurement data.

公开(公告)号：US09555171B2

公开(公告)日：2017-01-31

申请号：US12894271

申请日：2010-09-30

申请人： Mehmet Ziya Sengun ,  William Parrish ,  Brooks J. Story ,  Kristian DiMatteo ,  Gregory R. Whittaker ,  Douglas Allen Fifolt

发明人： Mehmet Ziya Sengun ,  William Parrish ,  Brooks J. Story ,  Kristian DiMatteo ,  Gregory R. Whittaker ,  Douglas Allen Fifolt

IPC分类号： A01N1/02 ,  B01D21/26 ,  B01D21/00 ,  A61M1/02 ,  A61M1/36 ,  B01L3/00

CPC分类号： B04B11/04 ,  A61K35/16 ,  A61K35/19 ,  A61M1/029 ,  A61M1/3693 ,  A61M2202/0427 ,  B01D21/262 ,  B01D2221/10 ,  B01L3/5021 ,  B01L2300/028 ,  B01L2300/0832 ,  B01L2400/0409 ,  B01L2400/0478 ,  B01L2400/0622 ,  B04B5/0414 ,  B04B2011/046

摘要： A method provides for procuring platelet rich plasma (PRP) from a sample of whole blood in a vial. The method includes the steps of: separating the whole blood into layers through centrifugation with an upper layer containing platelet poor plasma (PPP) and a PRP layer below the upper layer containing PRP; adjusting an end point of a first range of motion of an extractor relative to a position of the PRP layer; moving the extractor through the first range of motion through the vial, PPP passing out from the upper layer through the extractor; and after the extractor reaches the end point of the first range of motion, extracting the PRP through the extractor and collecting the PRP.

摘要翻译： 一种方法提供从小瓶中的全血样品中获得富血小板血浆（PRP）。 该方法包括以下步骤：通过离心将全血分离成含有血小板不足等离子体（PPP）的上层和含有PRP的上层下方的PRP层; 调整提取器相对于PRP层的位置的第一运动范围的终点; 将提取器移动通过小瓶的第一运动范围，PPP从上层通过提取器传出; 并且在提取器到达第一运动范围的终点之后，通过提取器提取PRP并收集PRP。

公开(公告)号：US09517464B2

公开(公告)日：2016-12-13

申请号：US14096940

申请日：2013-12-04

申请人： Ian K. Glasgow ,  Brian Kolb ,  Andrea Habura

发明人： Ian K. Glasgow ,  Brian Kolb ,  Andrea Habura

IPC分类号： G01F25/00 ,  B01L3/02 ,  B01L3/00

CPC分类号： B01L3/0293 ,  B01L3/5027 ,  B01L2200/148 ,  B01L2300/028 ,  B01L2300/0838 ,  B01L2400/0406 ,  G01F17/00 ,  G01F25/0084 ,  G01F25/0092

摘要： A measurement device containing one or more capillaries to measure the volume of a dispensed fluid and determine the volumetric accuracy of the dispensing device. The measurement device can contain a reservoir containing the fluid to be measured and there may be an additional reservoir for a secondary fluid. A viewing window is necessary to complete a manual measurement and may include a magnifying lens. The liquid well by the capillary inlet may be shaped such that the measurement fluid is directed toward the capillary. The well may have features designed to position the dispensing device toward the capillary, or to position the well proximal to the capillary after it is filled. The well may also have surfaces or coatings which attract or do not attract various types of substances. The measurement device may interface with sensors to output measurement data.

摘要翻译： 包含一个或多个毛细管以测量分配的流体的体积并确定分配装置的体积精度的测量装置。 测量装置可以容纳包含要测量的流体的储存器，并且可以存在用于次级流体的另外的储存器。 观察窗口是完成手动测量所必需的，并且可以包括放大镜。 通过毛细管入口的液体阱可以被成形为使得测量流体被引向毛细管。 井可以具有设计成将分配装置朝向毛细管定位的特征，或者在将其充满后将孔定位在毛细管附近。 井也可能具有吸引或不吸引各种物质的表面或涂层。 测量设备可以与传感器连接以输出测量数据。

公开(公告)号：US20160305876A1

公开(公告)日：2016-10-20

申请号：US14688331

申请日：2015-04-16

申请人： Advanced Technology Applications, LLC

发明人： Jeffery R.X. Auld ,  James E. Smith

IPC分类号： G01N21/55 ,  G01N21/31

CPC分类号： B01L3/5027 ,  B01L2300/028 ,  B01L2300/0803 ,  B01L2300/16 ,  B01L2300/168 ,  G01N21/253 ,  G01N21/31 ,  G01N21/314 ,  G01N35/00069 ,  G01N2201/061

摘要： A method may include steps of binding an analyte to a ligand, exposing the analyte to light of differing wavelengths, and observing a difference in spectral response of the analyte at the differing wavelengths. Further steps may include comparing the observed difference with a known difference in spectral response of a reference substance at the differing wavelengths, and determining whether the observed difference meets a predetermined threshold of identity with the known difference. The method may be performed with reference to a surface having a reflective area with a known size a non-reflective area adjacent to the reflective area. The method may thus include the steps of providing a ligand in alignment with the non-reflective area of the surface, and binding an analyte to the ligand in a position reaching across the reflective area. Further steps may include forming an image of the analyte and the reflective area, observing the size of analyte relative to the reflective area in the image, and comparing the observed size of the analyte with a known size of a reference subject to determine a degree of identity between the analyte and the reference subject.

摘要翻译： 方法可以包括将分析物结合到配体，将分析物暴露于不同波长的光并且观察分析物在不同波长处的光谱响应差异的步骤。 另外的步骤可以包括将观察到的差异与在不同波长处的参考物质的光谱响应中的已知差异进行比较，以及确定观察到的差异是否满足具有已知差异的预定的身份阈值。 该方法可以参照具有已知尺寸的具有与反射区域相邻的非反射区域的反射区域的表面来执行。 因此，该方法可以包括以下步骤：提供与表面的非反射区域对准的配体，以及将分析物与配体结合到穿过反射区域的位置。 另外的步骤可以包括形成分析物和反射区域的图像，观察分析物相对于图像中的反射区域的大小，以及将观察到的分析物的大小与参考对象的已知大小进行比较，以确定分析物的程度 分析物与参考对象之间的身份。

公开(公告)号：US20150037833A1

公开(公告)日：2015-02-05

申请号：US14388200

申请日：2013-03-27

申请人： Mark James Fisher ,  Sally M. McFall ,  Robert D. Hillman ,  Zachary J. Walker ,  Jacqueline Rene Groves ,  Jennifer Reed ,  David M. Kelso

发明人： Mark James Fisher ,  Sally M. McFall ,  Robert D. Hillman ,  Zachary J. Walker ,  Jacqueline Rene Groves ,  Jennifer Reed ,  David M. Kelso

IPC分类号： C12Q1/24

CPC分类号： C12Q1/24 ,  B01L3/50825 ,  B01L2200/025 ,  B01L2300/028 ,  B01L2300/042 ,  B01L2300/044 ,  B01L2300/0654

摘要： The present invention relates to a system for collecting and preparing a body fluid sample, the system comprising a sample container (10) comprising a sample cup (38) for receiving the sample, said sample cup comprising graduated indicator markings (14) corresponding to equal increments of sample volume, a removable lid (16) for sealably covering said sample cup, said lid having an access point which is sealed by a septum, and a removable cap (22) which is effective to cover said access point, and a delivery device for containing a plurality of predetermined reagent doses which are to be added to a sample within the sample container in the predetermined doses relative to the volume of the sample.

摘要翻译： 本发明涉及一种用于收集和制备体液样品的系统，该系统包括样品容器（10），样本容器（10）包括用于接收样品的样品杯（38），所述样品杯包括对应于相等的刻度指示符标记（14） 样品体积增量，用于密封地覆盖所述样品杯的可移除盖（16），所述盖具有由隔膜密封的接入点和可有效覆盖所述接入点的可移除盖（22），以及递送 用于以预定剂量相对于样品的体积容纳要添加到样品容器内的样品的多个预定试剂剂量的装置。

公开(公告)号：US20140260698A1

公开(公告)日：2014-09-18

申请号：US13797456

申请日：2013-03-12

申请人： TAICHUNG VETERANS GENERAL HOSPITAL

发明人： Ming-Feng WU

IPC分类号： B01L3/02

CPC分类号： B01L3/021 ,  B01L3/0272 ,  B01L2300/028 ,  B01L2400/0481 ,  G01F19/00

摘要： A transparent liquid suction measuring device comprises a conduit portion, a main body, and a suction generating portion. Liquid can be sucked into the main body via the conduit portion. The main body comprises a chamber to accommodate the liquid. The chamber has many inward projecting elements, a corresponding area, and many outward projecting elements. The inward projecting elements occupy an inward projecting volume that is compensated by an outward projecting volume formed by the outward projecting elements. So, an accommodating volume of the chamber is constantly maintained. When the inward projecting elements are visually observing from a corresponding area through the chamber, magnifying effect is generated. These outward projecting elements can be observed to acquire the liquid volume. Therefore, the advantages includes magnifying scales through liquid lens effects, having a compensation design to maintain measuring accuracy, and having a rough structure to make scales much visually obvious.

摘要翻译： 透明的液体吸入测量装置包括导管部分，主体和抽吸产生部分。 液体可以通过管道部分被吸入主体。 主体包括容纳液体的室。 该室具有许多向内突出的元件，相应的区域和许多向外突出的元件。 向内突出的元件占据由向外突出的体积，其由外向突出的元件形成的向外突出的体积补偿。 因此，恒定地保持腔室的容纳容积。 当向内突出的元件从通过该室的对应区域目视观察时，产生放大效果。 可以观察到这些向外突出的元件以获得液体体积。 因此，优点包括通过液晶透镜效果的放大镜，具有补偿设计以保持测量精度，并且具有粗糙的结构，使得尺寸在视觉上显得明显。

公开(公告)号：US08211365B2

公开(公告)日：2012-07-03

申请号：US13270758

申请日：2011-10-11

申请人： Joseph M. Chiapperi ,  Mary Kay Golisano

发明人： Joseph M. Chiapperi ,  Mary Kay Golisano

IPC分类号： G01N21/03 ,  G01N33/86

CPC分类号： B01L3/5025 ,  B01L2200/143 ,  B01L2300/028 ,  B01L2400/0409 ,  G01N33/5304 ,  Y10S436/809 ,  Y10T436/25

摘要： An immunodiagnostic test card includes a plurality of transparent chambers wherein each chamber includes a quantity of testing material that combines with a patient sample, when mixed, to produce an agglutination reaction. A plurality of indicia are disposed to aid in the manufacture and determining the usability of the cards prior to test and also in objectively grading the agglutination reactions that are formed or lack of agglutination.

摘要翻译： 免疫诊断测试卡包括多个透明室，其中每个室包括与混合的患者样品组合的一定数量的测试材料以产生凝集反应。 设置多个标记以帮助制造和确定试验前卡的可用性，并且还客观地分级形成的凝集反应或不凝集。

公开(公告)号：US08210057B2

公开(公告)日：2012-07-03

申请号：US12609379

申请日：2009-10-30

申请人： Robert E. Thorne ,  Guanhan Chew

发明人： Robert E. Thorne ,  Guanhan Chew

IPC分类号： G01N1/00

CPC分类号： G01N1/286 ,  B01L3/505 ,  B01L3/5088 ,  B01L2200/147 ,  B01L2300/028

摘要： Microfabricated tools useful for manipulating small, delicate samples are formed from thin plastic films. The films have a small thickness (preferably 5 to 50 micrometers and typically 10 micrometers) and small lateral dimensions (preferably 2 mm or less and typically 0.1 to 1 mm) so that they are reasonably flexible, but are preferably curved by being wrapped around a cylindrical or flat post to give them some rigidity. The softness and thinness of the plastic reduce risk of sample damage during incidental contact with the tool. Its thinness makes it optically and X-ray transparent, so that the samples can be clearly visualized during manipulations and so that the tools can be used to collect X-ray data from samples. As an option, an X-ray sensitive phosphor is incorporated in the film at low concentration. This allows the X-ray beam to be visually located on the mount or tool. The plastic can also be treated to obtain a desired hydrophobicity or hydrophilicity, mechanically embossed or abraded, or coated with films (for example, of polyethylene glycol via pegylation procedures or of PDMS) that promote or inhibit sample adhesion.

摘要翻译： 用于操作小而精细样品的微型工具由薄塑料膜形成。 膜的厚度（优选为5至50微米，典型为10微米）和较小的横向尺寸（优选2mm或更小，通常为0.1至1毫米），使得它们具有相当的柔性，但优选通过围绕 圆柱形或扁平柱，给它们一些刚性。 塑料的柔软性和薄度降低了与工具偶然接触时样品损坏的风险。 其薄度使其光学和X射线透明，使样品在操作过程中可以清晰可视，从而可以使用这些工具从样品采集X射线数据。 作为选择，在低浓度下将X射线敏感性荧光体掺入膜中。 这允许X射线束在视觉上位于安装件或工具上。 也可以处理塑料以获得所需的疏水性或亲水性，机械压花或磨损，或涂覆促进或抑制样品粘附的膜（例如聚乙二醇通过聚乙二醇化程序或PDMS）。