公开(公告)号：US10828622B2

公开(公告)日：2020-11-10

申请号：US15736721

申请日：2016-06-28

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Mukhles Ibrahim Sowwan ,  Cathal Cassidy ,  Vidya Dhar Singh

IPC: B01J37/34 ,  B01J23/44 ,  B01J35/00 ,  B01J23/58 ,  H01M4/92 ,  B01J23/02 ,  B01J33/00 ,  B01J37/00 ,  B01J37/02 ,  B01J37/14 ,  H01M8/1011

Abstract: A novel catalyst includes a plurality of nanoparticles, each nanoparticle including a core made of a catalytic metal and a porous shell surrounding the core, made of metal oxide, the porous shell preserving a catalytic function of the core and reducing reduction of the core and coalescence of the nanoparticles.

公开(公告)号：US10435383B2

公开(公告)日：2019-10-08

申请号：US15560858

申请日：2016-02-01

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Fujie Tanaka ,  Sherida Johnson

IPC: C07D307/22 ,  C07D309/14

Abstract: The present invention can provide novel C-glycoside derivatives which are biologically important under high stereoselective, mild, atom economical condition.

公开(公告)号：US20190169125A1

公开(公告)日：2019-06-06

申请号：US16321137

申请日：2016-09-28

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Fujie TANAKA ,  Feng YIN

IPC: C07D209/54 ,  C07D207/16 ,  C07C205/51

Abstract: The present invention relates to a process for preparing 3-pyrrolidine carboxylic acid derivatives, and particularly a simple process for preparing 5-substituted 3-pyrrolidine carboxylic acid derivatives. In addition, the present invention relates to a novel pyrrolidine carboxylic acid derivative, its manufacture, pharmaceutical compositions containing it and its use as a catalyst.

公开(公告)号：US20190086876A1

公开(公告)日：2019-03-21

申请号：US16130469

申请日：2018-09-13

Applicant: FUJITSU LIMITED ,  Okinawa Institute of Science and Technology School Corporation

Inventor： Tomotake Sasaki ,  Eiji Uchibe ,  Kenji Doya ,  Hirokazu Anai ,  Hitoshi Yanami ,  Hidenao Iwane

IPC: G05B13/02 ,  G06F15/18 ,  G06F17/16

Abstract: A non-transitory, computer-readable recording medium stores a program of reinforcement learning by a state-value function. The program causes a computer to execute a process including calculating a TD error based on an estimated state-value function, the TD error being calculated by giving a perturbation to each component of a feedback coefficient matrix that provides a policy; calculating based on the TD error and the perturbation, an estimated gradient function matrix acquired by estimating a gradient function matrix of the state-value function with respect to the feedback coefficient matrix for a state of a controlled object, when state variation of the controlled object in the reinforcement learning is described by a linear difference equation and an immediate cost or an immediate reward of the controlled object is described in a quadratic form of the state and an input; and updating the feedback coefficient matrix using the estimated gradient function matrix.

公开(公告)号：US20190033527A1

公开(公告)日：2019-01-31

申请号：US16036517

申请日：2018-07-16

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Rafino Miguel James Murphy ,  Fuchuan Lei ,  Jonathan Ward ,  Sile Nic Chormaic ,  Yong Yang

IPC: G02B6/26 ,  C03B37/15 ,  B23K26/00 ,  B23K26/073 ,  B23K26/0622 ,  B23K26/04 ,  B23K26/354 ,  B23K26/352 ,  B23K26/06

Abstract: A tunable, all-optical, coupling method for a high-Q silica microsphere and an optical waveguide is disclosed. By means of a novel optical nanopositioning method, induced thermal expansion of an asymmetric microsphere stem for laser powers up to 211 mW is observed and used to fine tune the microsphere-waveguide coupling. Microcavity displacements ranging from (0.61±0.13)−(3.49±0.13) μm and nanometer scale sensitivities varying from (2.81±0.08)−(17.08±0.76) nm/mW are obtained. Additionally, an apparent linear dependency of coupling distance on stem laser heating is achieved. Using these methods, coupling can be altered such that the differing and customizable coupling regimes can be achieved.

公开(公告)号：US10125074B2

公开(公告)日：2018-11-13

申请号：US15560868

申请日：2016-02-01

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Fujie Tanaka ,  Dongxin Zhang

IPC: C07C49/00 ,  C07C69/00 ,  C07C227/30 ,  C07C49/753 ,  C07C69/738 ,  C07D333/22 ,  C07D333/24 ,  C07C227/10 ,  C07C229/34 ,  C07C49/255 ,  C07C49/747 ,  C07C227/34 ,  C07C227/42 ,  A61K31/02 ,  A61K31/045

Abstract: The present invention relates to novel tertiary alcohol derivatives substituted with aryl and trifluoromethyl, and optical isomers thereof. In addition, the present invention also relates to methods for the preparation and use as enantiomer recognition agent thereof. The present invention provides pharmaceutical composition and use as therapeutically active substance thereof.

公开(公告)号：US20180193820A1

公开(公告)日：2018-07-12

申请号：US15736721

申请日：2016-06-28

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Mukhles Ibrahim SOWWAN ,  Cathal CASSIDY ,  Vidya Dhar SINGH

IPC: B01J23/44 ,  B01J23/02 ,  B01J35/00 ,  B01J33/00 ,  B01J37/34 ,  B01J37/00 ,  B01J37/02 ,  B01J37/14

Abstract: A novel catalyst includes a plurality of nanoparticles, each nanoparticle including a core made of a catalytic metal and a porous shell surrounding the core, made of metal oxide, the porous shell preserving a catalytic function of the core and reducing reduction of the core and coalescence of the nanoparticles.

公开(公告)号：US20180178207A1

公开(公告)日：2018-06-28

申请号：US15754091

申请日：2016-08-18

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Stephan STEINHAUER ,  Vidya Dhar SINGH ,  Mukhles Ibrahim SOWWAN

IPC: B01J37/02 ,  B01J23/89 ,  B01J35/00 ,  B01J35/06 ,  B01J37/14 ,  B01J37/34 ,  C23C16/40

CPC classification number: B01J37/0226 ,  B01J23/892 ,  B01J23/8926 ,  B01J35/0013 ,  B01J35/06 ,  B01J37/14 ,  B01J37/347 ,  B82Y30/00 ,  B82Y40/00 ,  C01G3/02 ,  C01P2004/03 ,  C01P2004/04 ,  C01P2004/16 ,  C01P2004/80 ,  C23C16/40 ,  C30B29/16 ,  C30B29/60 ,  C30B33/00

Abstract: A method for manufacturing nanoparticle decorated nanowires by a vacuum deposition system having a deposition chamber and an aggregation chamber connected thereto includes: mounting a metal member in the deposition chamber; performing thermal oxidization of the metal member in the deposition chamber in an oxygen atmosphere so as to grow metal oxide nanowires on a surface of the metal member; without breaking vacuum in the vacuum deposition system, generating a vapor of a catalytic metal particles clusters in the aggregation chamber that is connected to the deposition chamber; and without breaking vacuum in the vacuum deposition system, transporting the generated catalytic metal particles clusters to the deposition chamber so as to decorate the metal oxide nanowires with catalytic metal nanoparticles made of the catalytic metal particles.

公开(公告)号：US20180118703A1

公开(公告)日：2018-05-03

申请号：US15560858

申请日：2016-02-01

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Fujie TANAKA ,  Sherida JOHNSON

IPC: C07D307/22 ,  C07D309/14

CPC classification number: C07D307/22 ,  C07D309/14

Abstract: The present invention can provide novel C-glycoside derivatives which are biologically important under high stereoselective, mild, atom economical condition.

公开(公告)号：US20170338430A1

公开(公告)日：2017-11-23

申请号：US15523500

申请日：2015-11-05

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Yabing Qi ,  Min-Cherl Jung ,  Sonia Ruiz Raga

IPC: H01L51/42 ,  H01L51/00

CPC classification number: H01L51/4246 ,  H01L51/001 ,  H01L51/002 ,  H01L51/0083 ,  H01L51/4226 ,  H01L51/4293 ,  Y02E10/549 ,  Y02P70/521

Abstract: An optoelectronic device is provided, the p-doped HTL device comprising an active layer comprising organometal halide perovskite and a hole transport layer (HTL) formed by vacuum evaporation and configured to transport hole carriers. The HTL includes a first sublayer comprising a hole transport material (HTM) doped with an n-dopant and disposed adjacent to the active layer, a second sublayer comprising the HTM that is undoped and disposed adjacent to the first sublayer, and a third sublayer comprising the HTM doped with a p-dopant and disposed adjacent to the second sublayer. The doping concentration of the n-dopant for the n-doped sublayer is determined to match the highest occupied molecular orbital energy level of the n-doped sublayer with the valence band maximum energy level of the perovskite active layer.